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The Peripheral Actions Of 5 Hydroxytryptamine
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Book Synopsis The Peripheral Actions of 5-hydroxytryptamine by : John R. Fozard
Download or read book The Peripheral Actions of 5-hydroxytryptamine written by John R. Fozard and published by . This book was released on 1989 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the advent of a number of new drugs with therapeutic promise, there has been an increased interest in the properties of 5-hydroxytryptamine (5-HT, serotonin). This book describes the major recent advances in this area, specifically with respect to the actions of 5-HT in the periphery. The scope is broad, covering 5-HT synthesis and catabolism, its receptors and their second messenger transduction systems, and the functional responses to 5-HT in peripheral tissues. Developments in the treatment of cardiovascular, gastrointestinal, and peripheral vascular disease are also discussed. Written by scientists actively working in the field, this book provides an extensive, authoritative, and up-to-date account of this important area of biomedical science.
Book Synopsis Serotonin Receptors in Neurobiology by : Amitabha Chattopadhyay
Download or read book Serotonin Receptors in Neurobiology written by Amitabha Chattopadhyay and published by CRC Press. This book was released on 2007-05-17 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from l
Book Synopsis Handbook of Neurochemistry by : Abel Lajtha
Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of the Behavioral Neurobiology of Serotonin by : Christian P. Muller
Download or read book Handbook of the Behavioral Neurobiology of Serotonin written by Christian P. Muller and published by Academic Press. This book was released on 2009-12-30 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. - The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system - Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others - The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community - Of great value not only for researchers and experts, but also for students and clinicians as a background reference
Book Synopsis Pharmacology of Ionic Channel Function: Activators and Inhibitors by : M. Endo
Download or read book Pharmacology of Ionic Channel Function: Activators and Inhibitors written by M. Endo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells maintain uneven distribution of Na, K and Ca ions across the cell membrane and membranes of intracellular organellae. Cells exert their functions by allowing for some ion to cross the membrane through ion channels which either produces an electrical effect across the membrane or switches on a series of chemical or physicochemical reactions. This is a comprehensive book about these vitally important ion channels with detailed description of the molecular structure and function and especially of activators and inhibitors. All chapters are written by renowned specialists in their field.
Book Synopsis The Serotonin Receptors by : Bryan L. Roth
Download or read book The Serotonin Receptors written by Bryan L. Roth and published by Springer Science & Business Media. This book was released on 2008-08-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Book Synopsis 5-HT4 Receptors in the Brain and Periphery by : Richard M. Eglen
Download or read book 5-HT4 Receptors in the Brain and Periphery written by Richard M. Eglen and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.
Download or read book Serotonin written by Paul M. Pilowsky and published by Academic Press. This book was released on 2018-09-21 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin: The Mediator That Spans Evolution provides a comprehensive review of the widespread roles for serotonin in respiratory, cardiovascular and thermoregulatory control, and for growth and development in early life. This important resource highlights serotonin's role in normal (unstressed) conditions, and in response to a variety of physiological stressors. It focuses on new animal models, comparing and contrasting data from mice and rats. In addition, the book compares and contrasts the physiological effects of brain and blood serotonin systems and includes new data suggesting that the influence of serotonin is in part through the regulation of gene expression. Finally, it discusses the role of serotonin system dysfunction in a variety of pathophysiological conditions, including sleep apnea, obesity and hypertension, and presents compelling evidence that this dysfunction is involved in Sudden Infant Death Syndrome (SIDS). - Includes the latest information on new animal models of serotonin system dysfunction - Explores the wide scope of serotonin's influence on multiple organ and physiological systems - Highlights the autonomous functioning of the brain and body serotonin systems - Provides compelling evidence of serotonin dysfunction in SIDS, a leading cause of death in infancy
Download or read book Serotonin written by Fatima Shad Kaneez and published by BoD – Books on Demand. This book was released on 2017-07-26 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin - A Chemical Messenger Between All Types of Living Cells is a very interesting book on the most ancient neurotransmitter, hormone and trophic factor serotonin or 5-hydroxytryptamine (5-HT). This unique chemical is present in all living cells including plants and animals. This book will take us through a serene journey of the evolutionary history of serotonin and its role from man to mollusk. There are many interesting chapters incorporated in this book, including novel approaches for detecting minor metabolites of serotonin in human plasma, production and function of serotonin in cardiac cells, immuno-thrombotic effects of serotonin in platelets to the identification and localization of serotonin in the nervous system and gonad of bivalve mollusks.
Book Synopsis Biological Aspects of Affective Disorders by : Roger W. Horton
Download or read book Biological Aspects of Affective Disorders written by Roger W. Horton and published by . This book was released on 1991 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological research in the affective disorders has been an international growth industry for several years. Biological Aspects of Affective Disorders is a comprehensive introduction to the biochemical, pharmacological, and genetic aspects constituting the abnormalities that may underline the diseases of depression and mania, together with the current understanding of the clinical features and management of affected patients.It will be of great value especially to young researchers from all disciplines contributing to this area and to trainee psychiatrists.
Download or read book 5-HT2B Receptors written by Luc Maroteaux and published by Springer Nature. This book was released on 2021-03-12 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume provides a comprehensive assessment of the roles played by 5-HT2B receptors in humans. These receptors have been shown to play an important role is the cardiac, intestinal, and central nervous systems as well as in bone marrow formation and growth. In this book, expert researchers present their findings on molecular and physiological/pathological aspects of 5-HT2B receptors. The molecular section includes a discussion of the genetics of 5-HT2B receptors and impulse control. The physiological section covers their role in many biological systems including the nervous system, the heart, and the lungs.
Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Download or read book Serotonin written by E. Mylecharane and published by Springer. This book was released on 2016-01-03 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series contains edited proceedings of the satellite symposia of the ninth IUPHAR congress held in August 1984. This volume examines the properties of serotonin and its actions.
Book Synopsis 5-HT2C Receptors in the Pathophysiology of CNS Disease by : Giuseppe Di Giovanni
Download or read book 5-HT2C Receptors in the Pathophysiology of CNS Disease written by Giuseppe Di Giovanni and published by Springer Science & Business Media. This book was released on 2010-11-30 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of Springer’s “The Receptors,” series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors’ therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson’s disease, Prader-Willi Syndrome, Alzheimer’s disease and epilepsy.
Book Synopsis Serotonin and Sleep: Molecular, Functional and Clinical Aspects by : Jaime M. Monti
Download or read book Serotonin and Sleep: Molecular, Functional and Clinical Aspects written by Jaime M. Monti and published by Springer Science & Business Media. This book was released on 2008-03-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.
Book Synopsis Macromolecular Protein Complexes III: Structure and Function by : J. Robin Harris
Download or read book Macromolecular Protein Complexes III: Structure and Function written by J. Robin Harris and published by Springer Nature. This book was released on 2020-11-30 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Cytokines, Stress, and Depression by : Robert Dantzer
Download or read book Cytokines, Stress, and Depression written by Robert Dantzer and published by Springer Science & Business Media. This book was released on 1999-07-31 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until a few years ago, cytokines were only known to immunologists; now these molecules have burst upon neurosciences and permeated several avenues of current research. This book examines the possible role of cytokines in mental depression, based on recent clinical and experimental data, and constitutes the first attempt to make a synthesis between the exciting new developments in cytokine research and their implications for the pathophysiology of mental disorders.
