The Pandemic Perhaps

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The Pandemic Perhaps

Author : Carlo Caduff
Publisher : Univ of California Press
ISBN 13 : 0520959760
Total Pages : 270 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis The Pandemic Perhaps by : Carlo Caduff

Download or read book The Pandemic Perhaps written by Carlo Caduff and published by Univ of California Press. This book was released on 2015-08-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2005, American experts sent out urgent warnings throughout the country: a devastating flu pandemic was fast approaching. Influenza was a serious disease, not a seasonal nuisance; it could kill millions of people. If urgent steps were not taken immediately, the pandemic could shut down the economy and “trigger a reaction that will change the world overnight.” The Pandemic Perhaps explores how American experts framed a catastrophe that never occurred. The urgent threat that was presented to the public produced a profound sense of insecurity, prompting a systematic effort to prepare the population for the coming plague. But when that plague did not arrive, the race to avert it carried on. Paradoxically, it was the absence of disease that made preparedness a permanent project. The Pandemic Perhaps tells the story of what happened when nothing really happened. Drawing on fieldwork among scientists and public health professionals in New York City, the book is an investigation of how actors and institutions produced a scene of extreme expectation through the circulation of dramatic plague visions. It argues that experts deployed these visions to draw attention to the possibility of a pandemic, frame the disease as a catastrophic event, and make it meaningful to the nation. Today, when we talk about pandemic influenza, we must always say “perhaps.” What, then, does it mean to engage a disease in the modality of the maybe?

The Pandemic Perhaps

Author : Carlo Caduff
Publisher : Univ of California Press
ISBN 13 : 0520284097
Total Pages : 270 pages
Book Rating : 4.5/5 (22 download)

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Book Synopsis The Pandemic Perhaps by : Carlo Caduff

America's Forgotten Pandemic

Author : Alfred W. Crosby
Publisher : Cambridge University Press
ISBN 13 : 1107394015
Total Pages : pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis America's Forgotten Pandemic by : Alfred W. Crosby

Download or read book America's Forgotten Pandemic written by Alfred W. Crosby and published by Cambridge University Press. This book was released on 2003-07-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Between August 1918 and March 1919 the Spanish influenza spread worldwide, claiming over 25 million lives - more people than perished in the fighting of the First World War. It proved fatal to at least a half-million Americans. Yet, the Spanish flu pandemic is largely forgotten today. In this vivid narrative, Alfred W. Crosby recounts the course of the pandemic during the panic-stricken months of 1918 and 1919, measures its impact on American society, and probes the curious loss of national memory of this cataclysmic event. This 2003 edition includes a preface discussing the then recent outbreaks of diseases, including the Asian flu and the SARS epidemic.

The Premonition: A Pandemic Story

Author : Michael Lewis
Publisher : W. W. Norton & Company
ISBN 13 : 0393881563
Total Pages : 211 pages
Book Rating : 4.3/5 (938 download)

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Book Synopsis The Premonition: A Pandemic Story by : Michael Lewis

Download or read book The Premonition: A Pandemic Story written by Michael Lewis and published by W. W. Norton & Company. This book was released on 2021-05-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times Bestseller For those who could read between the lines, the censored news out of China was terrifying. But the president insisted there was nothing to worry about. Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19. The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work. Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

Flu

Author : Gina Kolata
Publisher : Farrar, Straus and Giroux
ISBN 13 : 1429979356
Total Pages : 378 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Flu by : Gina Kolata

Download or read book Flu written by Gina Kolata and published by Farrar, Straus and Giroux. This book was released on 2011-04-01 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

The Business of Pandemics

Author : Jay Liebowitz
Publisher : CRC Press
ISBN 13 : 1000203891
Total Pages : 216 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis The Business of Pandemics by : Jay Liebowitz

Download or read book The Business of Pandemics written by Jay Liebowitz and published by CRC Press. This book was released on 2020-11-18 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nations and businesses across the globe have been working through the difficulties of dealing with the COVID-19 pandemic. Industry, academia, NGOs, and governments have been "feverishly" searching for ways to address this deadly virus, which may continue to spread for at least the next year and perhaps beyond (in terms of a resurgence and different strains). From a business standpoint, there have been dramatic effects on logistics and supply chains, economic downfalls, bailouts of major industries and small businesses, and far-reaching calamities from around the world. Even though the COVID-19 story is still in its making, this book focuses on the business of pandemics as applied to COVID-19. The book brings together a global panel of experts across industries and NGOs to help guide business executives and managers through the complex array of issues affecting business in the time of a pandemic. Offering solutions to the business of pandemics as applied to COVID-19, the book is written for organizational decision makers and leaders, as well as those involved in crisis management, public health, and related fields. Its chapters focus on key areas that relate to the business of pandemics, including Lessons learned to date Big data and simulation Logistics and supply-chain management challenges Conducting global business virtually Global economic impact Media and risk communication IT infrastructure and networking Social impact Online learning and educational innovations The new work-from-home environment Re-opening markets and businesses Crisis decision making using analytics and intuition With chapters authored by experts from leading organizations, including the World Health Organization, the RAND Corporation, and various universities throughout the world, The Business of Pandemics: The COVID-19 Story provides high-level guidance and insight for business leaders who must deal with the complexities and challenges presented by this unprecedented crisis.

The Great Influenza

Author : John M. Barry
Publisher : Penguin
ISBN 13 : 9780143036494
Total Pages : 580 pages
Book Rating : 4.0/5 (364 download)

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Book Synopsis The Great Influenza by : John M. Barry

Download or read book The Great Influenza written by John M. Barry and published by Penguin. This book was released on 2005-10-04 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 New York Times bestseller “Barry will teach you almost everything you need to know about one of the deadliest outbreaks in human history.”—Bill Gates "Monumental... an authoritative and disturbing morality tale."—Chicago Tribune The strongest weapon against pandemic is the truth. Read why in the definitive account of the 1918 Flu Epidemic. Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, "The final lesson of 1918, a simple one yet one most difficult to execute, is that...those in authority must retain the public's trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart." At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

The Threat of Pandemic Influenza

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309095042
Total Pages : 431 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Threat of Pandemic Influenza by : Institute of Medicine

Download or read book The Threat of Pandemic Influenza written by Institute of Medicine and published by National Academies Press. This book was released on 2005-04-09 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

Viral Modernism

Author : Elizabeth Outka
Publisher : Columbia University Press
ISBN 13 : 0231546319
Total Pages : 355 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis Viral Modernism by : Elizabeth Outka

Download or read book Viral Modernism written by Elizabeth Outka and published by Columbia University Press. This book was released on 2019-10-22 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The influenza pandemic of 1918–1919 took the lives of between 50 and 100 million people worldwide, and the United States suffered more casualties than in all the wars of the twentieth and twenty-first centuries combined. Yet despite these catastrophic death tolls, the pandemic faded from historical and cultural memory in the United States and throughout Europe, overshadowed by World War One and the turmoil of the interwar period. In Viral Modernism, Elizabeth Outka reveals the literary and cultural impact of one of the deadliest plagues in history, bringing to light how it shaped canonical works of fiction and poetry. Outka shows how and why the contours of modernism shift when we account for the pandemic’s hidden but widespread presence. She investigates the miasmic manifestations of the pandemic and its spectral dead in interwar Anglo-American literature, uncovering the traces of an outbreak that brought a nonhuman, invisible horror into every community. Viral Modernism examines how literature and culture represented the virus’s deathly fecundity, as writers wrestled with the scope of mass death in the domestic sphere amid fears of wider social collapse. Outka analyzes overt treatments of the pandemic by authors like Katherine Anne Porter and Thomas Wolfe and its subtle presence in works by Virginia Woolf, T. S. Eliot, and W. B. Yeats. She uncovers links to the disease in popular culture, from early zombie resurrection to the resurgence of spiritualism. Viral Modernism brings the pandemic to the center of the era, revealing a vast tragedy that has hidden in plain sight.

The End of October

Author : Lawrence Wright
Publisher : Vintage
ISBN 13 : 0593081145
Total Pages : 401 pages
Book Rating : 4.5/5 (93 download)

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Book Synopsis The End of October by : Lawrence Wright

Download or read book The End of October written by Lawrence Wright and published by Vintage. This book was released on 2021-04-27 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • From the Pulitzer Prize-winning author of The Looming Tower—a riveting thriller and “all-too-convincing chronicle of science, espionage, action and speculation” (The Wall Street Journal). At an internment camp in Indonesia, forty-seven people are pronounced dead with acute hemorrhagic fever. When epidemiologist Henry Parsons travels there on behalf of the World Health Organization to investigate, what he finds will have staggering repercussions. Halfway across the globe, the deputy director of U.S. Homeland Security scrambles to mount a response to the rapidly spreading pandemic leapfrogging around the world, which she believes may be the result of an act of biowarfare. And a rogue experimenter in man-made diseases is preparing his own terrifying solution. As already-fraying global relations begin to snap, the virus slashes across the United States, dismantling institutions and decimating the population. With his own wife and children facing diminishing odds of survival, Henry travels from Indonesia to Saudi Arabia to his home base at the CDC in Atlanta, searching for a cure and for the origins of this seemingly unknowable disease. The End of October is a one-of-a-kind thriller steeped in real-life political and scientific implications, filled with the insight that has been the hallmark of Wright’s acclaimed nonfiction and the full-tilt narrative suspense that only the best fiction can offer.

Bird Flu

Author : Marc Siegel
Publisher : Turner Publishing Company
ISBN 13 : 0470337842
Total Pages : 138 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Bird Flu by : Marc Siegel

Download or read book Bird Flu written by Marc Siegel and published by Turner Publishing Company. This book was released on 2008-05-02 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Marc Siegel is an articulate voice of reason in a world beset by hype and hysteria. We would be well advised to listen closely to what he has to say." -Jerome Groopman, M.D., staff writer, the New Yorker "Siegel cuts through the hype about the 'deadly' this and the 'lethal' that, and applies reason in seeking the answers." -John M. Barry, author of The Great Influenza: The Epic Story of the Deadliest Plague in History "Timely and needed. At such times, we need soothsayers and explicators to redirect the ready-fire-aim mindset. Siegel's book fulfills this role well." -The Journal of the American Medical Association As bird flu sweeps through Asia, the rest of the world has begun to worry that it might spread west and start infecting humans. As many experts have pointed out, an influenza pandemic is only a matter of time and that time could be now. Or is it? In Bird Flu, Dr. Marc Siegel cuts through the hype, the facts, the fears, and the realities to explain what has the experts so worried and why there's still plenty of reason to be calm. Among the questions he answers are: * What is bird flu, and who has it? * What can I do to protect my family? * Should I stockpile Tamiflu? * Will this be like the deadly Spanish flu of 1918? * Why is there no bird flu vaccine? * Will the annual flu shot protect me? In his sensible and entertaining style, Siegel looks at the advances we've made in treatments, the research still to be done, and the challenges ahead for Asia to lay out a realistic plan for ending this global threat. While a bird flu outbreak in the United States may or may not happen this year, there's still a great deal of work to be done in readying America for outbreaks of any kind.

The Pandemic Century

Author : Mark Honigsbaum
Publisher : Oxford University Press
ISBN 13 : 1787382648
Total Pages : 356 pages
Book Rating : 4.7/5 (873 download)

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Book Synopsis The Pandemic Century by : Mark Honigsbaum

Download or read book The Pandemic Century written by Mark Honigsbaum and published by Oxford University Press. This book was released on 2019-03-09 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like sharks, epidemic diseases always lurk just beneath the surface. This fast-paced history of their effect on mankind prompts questions about the limits of scientific knowledge, the dangers of medical hubris, and how we should prepare as epidemics become ever more frequent. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu and the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 'parrot fever' pandemic and the more recent SARS, Ebola, and Zika epidemics, the last 100 years have been marked by a succession of unanticipated pandemic alarms. Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behaviour and technologies play in the emergence and spread of microbial diseases.

The Contagion Next Time

Author : Sandro Galea
Publisher : Oxford University Press
ISBN 13 : 0197576427
Total Pages : 297 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis The Contagion Next Time by : Sandro Galea

Download or read book The Contagion Next Time written by Sandro Galea and published by Oxford University Press. This book was released on 2022 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: A better and healthier time to be alive than ever -- An unhealthy country -- An unhealthy world -- Who we are, the foundational forces -- Where we live, work, and play -- Politics, power, and money -- Compassion -- Social, racial, and economic justice -- Health as a public good -- Understanding what matters most -- Working in complexity and doubt -- Humility and informing the public conversation.

The Red Lotus

Author : Chris Bohjalian
Publisher : Vintage
ISBN 13 : 0385544812
Total Pages : 360 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis The Red Lotus by : Chris Bohjalian

Download or read book The Red Lotus written by Chris Bohjalian and published by Vintage. This book was released on 2020-03-17 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • From the New York Times bestselling author of The Flight Attendant comes a twisting story of love and deceit: an American man vanishes on a rural road in Vietnam, and his girlfriend follows a path that leads her home to the very hospital where they met. Alexis and Austin don’t have a typical “meet cute”—their first encounter involves Alexis, an emergency room doctor, suturing a bullet wound in Austin’s arm. Six months later, they’re on a romantic getaway in Vietnam: a bike tour on which Austin can show Alexis his passion for cycling, and can pay his respects to the place where his father and uncle fought in the war. But then Austin fails to return from a solo ride. Alexis’s boyfriend has vanished, the only clue left behind a bright yellow energy gel dropped on the road. As Alexis grapples with this bewildering loss, she starts to uncover a series of strange lies that force her to wonder: Where did Austin go? Why did he really bring her to Vietnam? And how much danger has he left her in? Set amidst the adrenaline-fueled world of the emergency room, The Red Lotus is a global thriller about those who dedicate their lives to saving people—and those who peddle death to the highest bidder. Look for Chris Bohjalian's new novel, The Lioness!

Very, Very, Very Dreadful

Author : Albert Marrin
Publisher : Knopf Books for Young Readers
ISBN 13 : 1101931485
Total Pages : 208 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Very, Very, Very Dreadful by : Albert Marrin

Download or read book Very, Very, Very Dreadful written by Albert Marrin and published by Knopf Books for Young Readers. This book was released on 2018-01-09 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: From National Book Award finalist Albert Marrin comes a fascinating look at the history and science of the deadly 1918 flu pandemic--and its chilling and timely resemblance to the worldwide coronavirus outbreak. In spring of 1918, World War I was underway, and troops at Fort Riley, Kansas, found themselves felled by influenza. By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself. Of all diseases, the 1918 flu was by far the worst that has ever afflicted humankind; not even the Black Death of the Middle Ages comes close in terms of the number of lives it took. No war, no natural disaster, no famine has claimed so many. In the space of eighteen months in 1918-1919, about 500 million people--one-third of the global population at the time--came down with influenza. The exact total of lives lost will never be known, but the best estimate is between 50 and 100 million. In this powerful book, filled with black and white photographs, nonfiction master Albert Marrin examines the history, science, and impact of this great scourge--and the possibility for another worldwide pandemic today. A Chicago Public Library Best Book of the Year!

Parenting in the Pandemic

Author : Rebecca Lowenhaupt
Publisher : IAP
ISBN 13 : 1648025226
Total Pages : 233 pages
Book Rating : 4.6/5 (48 download)

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Book Synopsis Parenting in the Pandemic by : Rebecca Lowenhaupt

Download or read book Parenting in the Pandemic written by Rebecca Lowenhaupt and published by IAP. This book was released on 2021-05-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: In March of 2020, our daily lives were upended by the COVID pandemic and subsequent school closures. With work and school shifting online, a new and ongoing set of demands has been placed on parents as school moved to online, virtual and hybrid models of learning. Families need to balance professional responsibilities with parenting and supporting their children’s education. As education professors, we find ourselves in a particular position as our expertise collides with the reality of schooling our own children in our homes during a global pandemic. This book focuses on the experiences of education faculty who navigate this relationship as pandemic professionals and pandemic parents. In this collection of personal essays, we explore parenting in the pandemic among education professors. Through our stories, we share our perspectives on this moment of upheaval, as we find ourselves confronting practical (and impractical) aspects of long held theories about what school could be, seeing up close and personally the pedagogy our children endure online, watching education policy go awry in our own living rooms (and kitchens and bathrooms), making high-stakes decisions about our children’s (and other children’s) access to opportunity, and trying to maintain our careers at the same time. In this collision of personal and professional identities, we find ourselves reflecting on fundamental questions about the purpose and design of schooling, the value of our work as education professors, and the precious relationships we hope to maintain with our children through this difficult time. Praise for Parenting in the Pandemic "Lowenhaupt and Theoharis have curated a magnificent collection of essays that captures the hopes, fears, tensions, and possibilities of parenting in a time of crisis. A gift to parents and educators everywhere as we continue to process and reflect on what the pandemic has taught us about what it means to educate others, and perhaps through a renewed imagination, our very own children." - Sonya Douglass Horsford, Teachers College, Columbia University "In this powerful collection of essays, we have a rare window into how the personal and professional worlds of academics collided during the COVID-19 pandemic. What emerges from these reflections is an intimate portrait of the longstanding tensions in our lives as public intellectuals and parents that have long burned as embers, but are now set ablaze by the public health, economic, and educational crisis we have lived through during the last year. Reading these essays will help us to see questions of education policy and practice in a new, more personal light." - Matthew Kraft, Brown University

How to Prevent the Next Pandemic

Author : Bill Gates
Publisher : Vintage
ISBN 13 : 0593534492
Total Pages : 235 pages
Book Rating : 4.5/5 (935 download)

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Book Synopsis How to Prevent the Next Pandemic by : Bill Gates

Download or read book How to Prevent the Next Pandemic written by Bill Gates and published by Vintage. This book was released on 2022-05-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Governments, businesses, and individuals around the world are thinking about what happens after the COVID-19 pandemic. Can we hope to not only ward off another COVID-like disaster but also eliminate all respiratory diseases, including the flu? Bill Gates, one of our greatest and most effective thinkers and activists, believes the answer is yes. The author of the #1 New York Times best seller How to Avoid a Climate Disaster lays out clearly and convincingly what the world should have learned from COVID-19 and what all of us can do to ward off another catastrophe like it. Relying on the shared knowledge of the world’s foremost experts and on his own experience of combating fatal diseases through the Gates Foundation, Gates first helps us understand the science of infectious diseases. Then he shows us how the nations of the world, working in conjunction with one another and with the private sector, how we can prevent a new pandemic from killing millions of people and devastating the global economy. Here is a clarion call—strong, comprehensive, and of the gravest importance.