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The Neutrophils
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Download or read book The Neutrophil written by Patrick Murphy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reflects the personal prejudices I have developed in twenty years of reading the scientific literature. I like monographs; good ones assemble a great deal of information in a logical sequence and in enough detail to enable one to see why current beliefs are held. For this purpose, it is entirely useless to write "as Smith has shown21 ,81,117 •••• " That only means that one must go to the library and turn up Smith's original papers, and one's object in reading a monograph is precisely to avoid that neces sity. One needs to know what Smith did and why he thought his observa tions proved whatever he claimed. Because life is short, it is impossible to deal with several thousand papers in this way, and the author must there fore select a relatively few papers that he regards as crucial. Often, several papers of equal merit might be quoted, and the selection is then arbitrary. I therefore apologize to authorities who do not find their work discussed. Omission does not mean that I thought their work was not valuable; it means only that I preferred to quote twenty references that people might read rather than two thousand that assuredly no one would read. Another strong prejUdice is that the full understanding of present knowledge requires one to know how present views have developed.
Book Synopsis Mast Cells and Basophils by : Gianni Marone
Download or read book Mast Cells and Basophils written by Gianni Marone and published by Academic Press. This book was released on 2000-05-25 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.
Book Synopsis Biochemistry and Physiology of the Neutrophil by : Steven W. Edwards
Download or read book Biochemistry and Physiology of the Neutrophil written by Steven W. Edwards and published by Cambridge University Press. This book was released on 1994-03-25 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic microorganisms. The development of these cells during haematopoiesis is described and the mechanisms that lead to the production of reactive oxidants and the intracellular signal transduction systems that lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally, there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.
Book Synopsis Neutrophil Methods and Protocols by : Mark T. Quinn
Download or read book Neutrophil Methods and Protocols written by Mark T. Quinn and published by Springer Science & Business Media. This book was released on 2007-08-02 with total page 1099 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Scientists and clinicians will find this collection an invaluable aid.
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Book Synopsis Role of Neutrophils in Disease Pathogenesis by : Maitham Khajah
Download or read book Role of Neutrophils in Disease Pathogenesis written by Maitham Khajah and published by BoD – Books on Demand. This book was released on 2017-06-07 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role of neutrophils in health as well as in the pathogenesis of various diseases. Section 1 provides a general background information regarding the mechanisms and various triggers of neutrophil extracellular traps (NETs) formation and their role in various infectious and noninfectious diseases (such as postinjury inflammation). Section 2 provides recent evidence regarding the role of neutrophils in the pathogenesis as well as a therapeutic target for selected disease conditions such as periodontal diseases, rheumatoid arthritis, and cystic fibrosis. Section 3 describes the anti-inflammatory properties of neutrophils with focus regarding their role in graft versus host disease. This book provides a wider picture with regard to the importance of this immune cell type in various diseases with focus on one of its recently discovered properties, NETs. Therapeutic targets aimed to modulate neutrophil functions might provide novel approaches in the treatment of various diseases of infectious and noninfectious origin.
Author :Marco A. Cassatella Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805575521 Total Pages :247 pages Book Rating :4.8/5 (55 download)
Book Synopsis The Neutrophil by : Marco A. Cassatella
Download or read book The Neutrophil written by Marco A. Cassatella and published by Karger Medical and Scientific Publishers. This book was released on 2003-01-01 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, neutrophils were often reduced to their ability to release preformed mediators and kill pathogens. The present volume of Chemical Immunology and Allergy, however, offers a very broad and timely view by highlighting the versatile functions of neutrophils in inflammatory, immune and antitumoral responses. Leading investigators uncover novel aspects of neutrophils, such as their capacity to control gene expression at the transcriptional level, or respond to proinflammatory cytokines, cytokine receptor chains (gc) and endogenous anti-inflammatory lipid mediators. Further points under discussion are neutrophils presenting antigens, activating T cells, participating in chemokine networking, and producing IL-12 and other cytokines during infectious diseases. Among the most original findings presented in this publication figure the observations that neutrophils cause increased vascular permeability during acute inflammation, regulate directly the angiogenic process, and influence tumor development. A final article offers a detailed description of the molecular processes affecting neutrophil cell death and survival. Unique in its field, this valuable volume is recommended reading not only for immunologists and pathologists, but also for cell biologists, hematologists and immunobiologists.
Book Synopsis The Neutrophil: Cellular Biochemistry and Physiology by : Maurice B. Hallett
Download or read book The Neutrophil: Cellular Biochemistry and Physiology written by Maurice B. Hallett and published by CRC Press. This book was released on 2018-01-18 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis and collation of the recent material regarding the role of the neutrophil in basic pathological processes is presented in this volume. The mechanisms of chemotaxis, secretion, phagocytosis, intracellular killing, oxygen radical production and arachidonate production are comprehensively reviewed. Stimulus response coupling in the neutrophil, with chapters on intracellular Ca2+, C-Kinase, phospholipid metabolism, microfilaments and membrane electrophysiology are extensively discussed. Each chapter provides a critical review by experts with over 1,000 cited references. Invaluable to graduate students and medical and scientific researchers, this book provides a unique, up-to-date account of cellular biochemistry and physiology of the neutrophil.
Download or read book The Neutrophil written by Jon S. Abramson and published by Oxford University Press, USA. This book was released on 1993 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third book in the group devoted to the "natural" immune system, this volume provides the ideal detailed, up-to-date overview of neutrophil function. Distilling new information alongside observations of the past, the book focuses on some of the most critical developments in currentneutrophil research. Specific examples of diseases resulting from neutrophil dysfunction and deficiency are brought to life by clinical case studies. An essential source of current research into this exciting field, this volume will be invaluable for advanced students and researchers in immunology,cell biology, and medicine.
Book Synopsis Neutrophils, The: New Outlook For Old Cells by : Dmitry I Gabrilovich
Download or read book Neutrophils, The: New Outlook For Old Cells written by Dmitry I Gabrilovich and published by World Scientific. This book was released on 1999-03-26 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable volume, written by group of internationally established scientists, presents an overview of the most recent findings on the biology of neutrophils. These cells have become a focus of attention in recent years because of their fascinating biochemistry and molecular biology and their ability to affect the functions of other cells. The book describes, in detail, the molecular events leading to neutrophil activation, migration, microbial killing, production of oxidative radicals and cytokines, and eventually to the death of these cells. It presents new information that has never been discussed in monographs before. It also gives a unique overview of the neutrophil's role in viral diseases, including Aids. Finally, the book describes how to improve the function of neutrophils and use these cells in the treatment of diseases.
Book Synopsis Encyclopedia of Medical Immunology by : Ian R. Mackay
Download or read book Encyclopedia of Medical Immunology written by Ian R. Mackay and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.
Author :Dmitry I. Gabrilovich Publisher :World Scientific Publishing Company ISBN 13 :9781860940828 Total Pages :362 pages Book Rating :4.9/5 (48 download)
Book Synopsis The Neutrophils by : Dmitry I. Gabrilovich
Download or read book The Neutrophils written by Dmitry I. Gabrilovich and published by World Scientific Publishing Company. This book was released on 1999 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable volume, written by group of internationally established scientists, present an overview of the most recent findings on the biology of neutrophils. These cells have become a focus of attention in recent years because of their fascinating biochemistry and molecular biology and their ability to affect the function of other cells. The book describes, in detail, the molecular events leading to neutrophil activation, migration, microbial killing, production of oxidative radicals and cytokines, and eventually to the death of these cells. It presents new information that has never been discussed in monographs before. It also gives a unique overview of the neutrophil's role in vital diseases, including Aids. Finally, the book describes how to improve the function of neutrophils and use these cells in the treatment of diseases.
Book Synopsis Neutrophils, The: New Outlook For Old Cells (2nd Edition) by : Dmitry I Gabrilovich
Download or read book Neutrophils, The: New Outlook For Old Cells (2nd Edition) written by Dmitry I Gabrilovich and published by World Scientific. This book was released on 2005-01-24 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a second edition of the book, which presents an overview of the most recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections and have been implicated in anti-tumor response. In addition, neutrophils represent a unique model for studying fundamental questions of cellular biochemistry and molecular biology. This book provides a detailed description of signal transduction, generation of reactive oxygen, and mechanisms of migration of these cells. It contains unique information on the neutrophil's role in viral infectious diseases and cancer. It also presents the recent advances in attempts to improve neutrophil function and use these cells in the treatment of diseases.
Book Synopsis The Resolution of Inflammation by : Adriano Rossi
Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Book Synopsis Cells of the Immune System by : Ota Fuchs
Download or read book Cells of the Immune System written by Ota Fuchs and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.
