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The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part B
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Book Synopsis The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part B by :
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part B written by and published by Academic Press. This book was released on 2022-09-03 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
Book Synopsis The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part A by :
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part A written by and published by Academic Press. This book was released on 2022-07-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome’s complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications. Examines Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating the Gilles de la Tourette Syndrome
Book Synopsis The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part A by :
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part A written by and published by Academic Press. This book was released on 2022-07-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome's complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications.
Book Synopsis The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects by : Peristera Paschou
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects written by Peristera Paschou and published by Frontiers Media SA. This book was released on 2018-03-13 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Book Synopsis Tourette Syndrome by : Davide Martino
Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Book Synopsis Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders by : Roger Kurlan
Download or read book Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders written by Roger Kurlan and published by CRC Press. This book was released on 2004-10-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on To
Book Synopsis Tourette Syndrome by : John T. Walkup
Download or read book Tourette Syndrome written by John T. Walkup and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes. Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Book Synopsis The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects by :
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Book Synopsis Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome by :
Download or read book Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome written by and published by Academic Press. This book was released on 2013-11-27 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome
Book Synopsis Marsden's Book of Movement Disorders by : Ivan Donaldson
Download or read book Marsden's Book of Movement Disorders written by Ivan Donaldson and published by Oxford University Press. This book was released on 2012-03-29 with total page 1512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
Book Synopsis Tourette Syndrome by : Thomas Newell Chase
Download or read book Tourette Syndrome written by Thomas Newell Chase and published by Lippincott Williams & Wilkins. This book was released on 1992 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents an encyclopedic account of the past decade's achievements in the study and treatment of Tourette Syndrome (TS) and associated behavioral and psychiatric disorders. More than 90 of the foremost authorities from all relevant basic science, clinical, and behavioral science disciplines highlight the major recent developments worldwide - from groundbreaking genetic and neurochemical research and studies using state-of-the-art neuroimaging technologies, to new concepts on the clinical spectrum and natural history of TS, increasing recognition of comorbid conditions, and improved strategies for pharmacotherapy and psychosocial management. The contributors assess the practical utility of current diagnostic criteria for TS and present extensive data on its natural history, its range of clinical manifestations, and its associated disorders. The findings indicate that the severity of TS varies widely among patients, that tics tend to diminish during adolescence and adulthood, and that comorbid conditions - such as obsessive-compulsive disorder and attention deficit hyperactivity disorder - are often the chief source of impairment. Much evidence suggests that these disturbances and the tics are manifestations of the same underlying diathesis. Noted investigators document significant findings on the mode of inheritance for TS, define the key methodological issues in genetic linkage studies, and describe molecular approaches to the search for the genetic locus for the syndrome. The book also includes new data implicating specific monoamine neurotransmitters and endogenous opioid peptides in the pathogenesis of TS. Other contributors present neuroimaging studies using MRI, PET, and SPECT to delineate brain mechanisms involved in TS. The book offers definitive guidelines on pharmacotherapy for tics and, particularly, for associated obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). Of special note are the discussions on treatment of OCD with serotonin reuptake inhibitors and on use of clonidine and stimulants for ADHD with comorbid tics. Additional chapters explore the potential of novel drugs and of nutritional interventions such as megavitamin therapy. Full consideration is also given to the role of behavioral and psychosocial therapies and the educational management of children with TS. This volume is an indispensable resource for all clinicians and investigators involved in the treatment or study of neuropsychiatric disorders. It exemplifies the creative application of the full range of current neuroscience and behavioral methodologies to a complex and important syndrome.
Book Synopsis Tourette's Syndrome -- Tics, Obsessions, Compulsions by : James F. Leckman
Download or read book Tourette's Syndrome -- Tics, Obsessions, Compulsions written by James F. Leckman and published by John Wiley & Sons. This book was released on 1998-11-09 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Früher wurde das Tourette-Syndrom (TS) als seltene Störung betrachtet; mittlerweile jedoch wurde erkannt, daß TS häufig in der Kindheit beginnt. Man weiß jetzt auch, daß die Anfälligkeit für TS über Generationen hinweg vererbt wird. Diagnose, Genetik, Phänomenologie, Geschichte und Behandlung von TS werden hier dargestellt, ausgehend von einem einmaligen Ansatz, der Beziehungen zwischen der Störung und dem normalen Entwicklungsweg herstellt. (8/98)
Book Synopsis Georges Gilles de la Tourette by : Olivier Walusinski
Download or read book Georges Gilles de la Tourette written by Olivier Walusinski and published by Oxford University Press, USA. This book was released on 2018-11-20 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19th Century brought many medical advances and discoveries in neurology, with the famed Parisian La Salpètrière hospital at its center. Medical giants such as Jean-Martin Charcot, Joseph Babinski, and even for a short time Sigmund Freud, walked these halls, so it is a wonder that, an equal among these men, very little exists in the literature on Georges Gilles de la Tourette. This biography is the first comprehensive volume to delve into the life, scholarship, writing, and hobbies of the famed doctor. In Part One, we learn Georges' family history, follow his schooling and mentorship under Charcot, travel to the Worlds Fair of 1900, evade an attempted assassination, all before succumbing to death by syphilis. Part Two provides an in-depth analysis of his neurological and psychiatric works, notably the epynomous neurological disorder that will forever remain "Tourette's Syndrome." Part Three looks at the lighter side of Georges, inspecting his favorite past-times as poet, historian, and art critic. Part Four brings an extensive bibliography of Georges' complete body of work. Author Olivier Walusinski pulls together unpublished family archives, Georges' correspondence with the Parisian journalist Georges Montorgueil, journal articles, and police archives to shed an original light on the famed doctor's life and lasting legacy. These archives have never before been studied or made available to the public, making this one of the first and most comprehensive biographies available and a must-have for any medical library.
Book Synopsis Tourette Syndrome by : Mary Robertson
Download or read book Tourette Syndrome written by Mary Robertson and published by OUP Oxford. This book was released on 2008-10-16 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette's Syndrome (TS) is an inherited neuropsychiatric disorder affecting up to 1% of the population. It is characterised by motor and vocal tics, and upsetting anti-social behaviour such as involuntary swearing and obscene gestures. This second edition of Tourette Syndrome: The Facts explains the causes of the syndrome, how it is diagnosed, and how to cope if you or a relative has been recently diagnosed. It provides information on the treatment and therapies that are available, and advice and on how individuals can manage their symptoms. It clearly explains the different presentations that can affected individuals, covering a spectrum from very mild to more uncommon severe forms of TS, and also discusses disorders that can be mistaken for TS. This edition contains a new chapters focussing on 'Education, employment and empowerment', and famous and successful people who achieved their goals despite their diagnosis. Essential reading for Tourette's sufferers, their relatives and friends, Tourette's Syndrome: The Facts will also be of use to clinicians, GPs, schoolteachers, and anyone seeking an accessible introduction to the disorder.
Book Synopsis Tourette's Syndrome and TIC Disorders by : Donald J. Cohen
Download or read book Tourette's Syndrome and TIC Disorders written by Donald J. Cohen and published by Wiley-Interscience. This book was released on 1988-05-10 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette's Syndrome is now recognized as a common, lifelong condition and a ``model'' disorder reflecting the interaction of genetic vulnerability and environmental factors. Along with progress in research on Tourette's and other tic disorders, new approaches to treating this neuropsychiatric disturbance are now attracting wide interest among mental health workers. This book provides the broadest, most up-to-date account of this group of disorders, their features, symptoms, etiology and diagnosis, and various psychosocial disorders with similar symptoms. It also presents a variety of environmental and pharmacological therapeutic approaches that underscore areas of disagreement in the field, as well as new genetic, neurochemical and pharmacologic knowledge. Contributors to this work are all leading researchers or clinicians.
Book Synopsis Pharmacological Treatment of Tics by : Andrea E. Cavanna
Download or read book Pharmacological Treatment of Tics written by Andrea E. Cavanna and published by Cambridge University Press. This book was released on 2020-07-30 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of the assessment, diagnosis, and pharmacological treatment of tics, this is a practical handbook designed for use in busy clinics by trainees and practitioners in a range of disciplines. The most widely used pharmacological treatment options for tics are covered, including first- and second-generation antidopaminergic medications, alpha-2 adrenergic medications, and other tic-suppressing medications. Particular care has been taken in covering the key medications used for tic control, detailing information such as the main pharmacodynamic and pharmacokinetic properties, tolerability profiles, clinically relevant interactions, and recommendations for use in special populations. International guidelines on the pharmacotherapy of tics are defined, with further reading lists of up-to-date literature supporting the reader in developing their knowledge. Delivering evidence-based applied guidance for the assessment and pharmacological treatment of tics, this is an essential manual for clinicians.
Book Synopsis A Transdiagnostic Approach to Obsessions, Compulsions and Related Phenomena by : Leonardo F. Fontenelle
Download or read book A Transdiagnostic Approach to Obsessions, Compulsions and Related Phenomena written by Leonardo F. Fontenelle and published by Cambridge University Press. This book was released on 2019-01-03 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a transdiagnostic framework, this book describes how mental health professionals can diagnose and treat OCD and related disorder.
