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The Mysterious World Of The Human Genome
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Book Synopsis The Mysterious World of the Human Genome by : Frank Ryan
Download or read book The Mysterious World of the Human Genome written by Frank Ryan and published by Prometheus Books. This book was released on 2016-02-16 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human genome is indeed a mysterious world, but, as this fascinating book shows, its vital secrets are now being uncovered. The latest studies are revealing exciting new discoveries, such as how the DNA and related chemical compounds in our cells work together to direct the processes of life. Scientists are not only unraveling how life evolved in the ancient past, but are also finding the keys to creating a healthier future. How does the minuscule chemical cluster in each of our 100 trillion cells accomplish the amazing feat of creating and maintaining our bodies? Frank Ryan, a physician and an evolutionary biologist, describes the complex ways in which the genome operates as a holistic system and not solely through genes coding for proteins—the building blocks of life. Also involved are elaborate switching mechanisms that regulate and control portions of our DNA, as well as the interplay of retroviruses and bacteria. This groundbreaking book explains that we are on the cusp of an amazing era of disease treatment and eradication.
Book Synopsis Mysterious Commonplace, The: A Life In Science by : Charles Delisi
Download or read book Mysterious Commonplace, The: A Life In Science written by Charles Delisi and published by World Scientific. This book was released on 2021-10-28 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acclaimed biomedical scientist Charles DeLisi tells the story of the rewards and frustrations of a life in science. The memoir spans half a century beginning in grade school when we find a somewhat shy boy deeply affected by the profoundly saddening sight of trees and woods in his beloved Bronx neighborhood being displaced by tons of steel and concrete. The reader is taken inside the mind of a complex non-conformist as he struggles with personal tragedy and ambivalence and moves from physics to history back to physics, and eventually into a career as a biomedical scientist. Among the most important parts of the memoir are his personal recollections of the years as director of the Department of Energy's Health and Environmental Research Programs when he fought the mighty battles that would move two Federal Agencies and place the Human Genome Project, including a unique ethical component, on the National Agenda. We watch an uncannily successful strategist and leader; who sees himself as an ordinary person, distinguished only by an intense passion for science, as he and his colleagues successfully engage Congressmen, his superiors at the DOE, and scientists of different backgrounds. The story closes where it began, with environmental change dominating the emotional landscape, as he and his colleagues struggle to fight the battle against a changing climate.
Download or read book DNA written by James D. Watson and published by Knopf. This book was released on 2009-01-21 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.
Download or read book DNA written by James D. Watson and published by Knopf. This book was released on 2017-08-22 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive insider's history of the genetic revolution--significantly updated to reflect the discoveries of the last decade. James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact--practical, social, and ethical--on our society and our world.
Book Synopsis Cracking the Genome by : Kevin Davies
Download or read book Cracking the Genome written by Kevin Davies and published by Simon and Schuster. This book was released on 2001-01-05 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1953, James Watson and Francis Crick discovered the double helix structure of DNA. The discovery was a profound, Nobel Prize-winning moment in the history of genetics, but it did not decipher the messages on the twisted, ladderlike strands within our cells. No one knew what the human genome sequence actually was. No one had cracked the code of life. Now, at the beginning of a new millennium, that code has been cracked. Kevin Davies, founding editor of the leading journal in the field, Nature Genetics, has relentlessly followed the story as it unfolded, week by week, for ten years. Here for the first time, in rich human, scientific, and financial detail, is the dramatic story of one of the greatest scientific feats ever accomplished: the mapping of the human genome. In 1990, the U.S. government approved a 15-year, $3 billion plan to launch the Human Genome Project, whose goal was to sequence the 3 billion letters of human DNA. At the helm of the project was James Watson, who resigned after only a couple of years, following a feud with National Institutes of Health (NIH) Director Bernadine Healy over gene patenting. His successor was the brilliant young medical geneticist Francis Collins, who had made his name discovering the gene for cystic fibrosis. As Davies reports, Collins is a devout Christian who has traveled to Africa to work in a missionary hospital. He believes the human genome sequence is "the language of God." Just as Collins became project director, J. Craig Venter, a maverick DNA sequencer and Vietnam veteran, was leaving the NIH to start his own private research institute. Venter had developed a simple "shotgun" strategy for sequencing DNA, and his fame skyrocketed when his new institute proved his sequencing system worked by becoming the first to sequence the entire genome of a microorganism. Only 3 percent of the human genome had been sequenced by early 1998, the public project's halfway point. That same year, Venter was approached by PE Corporation to launch a private human genome project. He stunned the world when he announced the formation of a new company to sequence the human genome in a mere three years for $300 million. A war of words broke out between public and private researchers. Undeterred, Venter built Celera Genomics with the motto "Speed matters. Discovery can't wait." and an $80 million supercomputer. While the insults intensified, Celera's stock price soared, tumbled, and soared again. Negotiations for cooperation between the public and private institutes began, only to fall apart in acrimony. Then in the spring of 2000 President Clinton stepped in, telling his science adviser to restart negotiations. History was about to be made. Davies captures the drama of this momentous achievement, drawing on his own genetics expertise and interviews with key scientists including Venter and Collins, as well as Eric Lander, an MIT computer wizard who refers to the public genome project as "the forces of good"; Kari Stefánsson, the genetics entrepreneur who is remaking Iceland's economy; and John Sulston, chief of the UK genome project, who led the charge against gene patenting. Davies has visited geneticists around the world to illustrate a vast international enterprise working on the frontier of human knowledge. Cracking the Genome is the definitive account of how the code that holds the answers to the origin of life, the evolution of humanity, and the future of medicine was broken.
Download or read book Decoding Life written by Ron Fridell and published by Twenty-First Century Books. This book was released on 2005-01-01 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery and purpose of DNA, as well as what understanding the human genome means for the future, are competently outlined in this volume. Pros and cons of many ethical issues are covered--from stem cell research to designer babies.
Book Synopsis The Mysterious Epigenome by : Thomas Woodward
Download or read book The Mysterious Epigenome written by Thomas Woodward and published by Kregel Publications. This book was released on 2011-12-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this creative and inventive treatment, authors Thomas E. Woodward and James P. Gills take readers on an exploration of the human epigenome. Acting as tour guides leading visitors through a 3-D model of a human cell, Woodward and Gills bring to life the human molecular makeup. Readers (as visitors) will get up close and personal with the minute details of human molecular structure, including E. coli, flagellum, a DNA helix, an RNA molecule, and more. By seeing it with their own eyes, readers will gain a better understanding of their genetic systems and a better appreciation for the Creator who put this all into place.
Book Synopsis Introduction to Genomics by : Arthur M. Lesk
Download or read book Introduction to Genomics written by Arthur M. Lesk and published by Oxford University Press. This book was released on 2017 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. The Online Resource Center accompanying Introduction to Genomics features: For students: *Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field *Hints and answers to end-of-chapter problems and exercises support your self-directed learning *Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research *Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature *Rotating figures allow you to visualize complex structures For instructors: *Downloadable figures from the book.
Book Synopsis Curiosity Guides: The Human Genome by : John Quackenbush
Download or read book Curiosity Guides: The Human Genome written by John Quackenbush and published by Charlesbridge Publishing. This book was released on 2011-02-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
Book Synopsis The Human Genome Project by : Thomas F. Lee
Download or read book The Human Genome Project written by Thomas F. Lee and published by . This book was released on 2014-09-01 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Curiosity Guides: The Human Genome by : John Quackenbush
Download or read book Curiosity Guides: The Human Genome written by John Quackenbush and published by Charlesbridge. This book was released on 2011-02-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
Download or read book Virusphere written by Frank Ryan and published by Rowman & Littlefield. This book was released on 2020-02-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating and long overdue examination of viruses - from what they are and what they do, to the vital role they have played in human history.What are viruses? Do they rely on genes, like all other forms of life? Do they follow the same patterns of evolution as plants and animals?Dr. Frank Ryan answers these questions and many more in a sweeping tour of illnesses caused by viruses. He examines the common cold, measles, chicken pox, herpes, mumps, and rubella, as well as less familiar maladies, such as rabies, "breakbone fever," hemorrhagic fevers like Ebola, and virus-induced cancers. Along the way, readers will learn about the behaviors of viruses and what drives them to infect a human host. Ryan explains the role of viruses in the evolution of life, revealing how viruses have changed us at the most intimate level, helping to make us quintessentially human.
Book Synopsis Economic Systems in the New Era: Stable Systems in an Unstable World by : Svetlana Igorevna Ashmarina
Download or read book Economic Systems in the New Era: Stable Systems in an Unstable World written by Svetlana Igorevna Ashmarina and published by Springer Nature. This book was released on 2020-10-10 with total page 901 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings book presents outcomes of the Innovative Economic Symposium – 2020 organized by the Institute of Technology and Business in České Budějovice (VŠTE) in Russia in collaboration with two universities: Financial University under the Government of the Russian Federation (Moscow) and Samara State University of Economics (Samara). The symposium aims to bring together experts and young scientists in economy, management, international relations, finance, marketing, and professional education from Asian and European countries, to share knowledge and experience and discuss issues related to stable economic development, international business, entrepreneurship, Industry 4.0, cooperation between educational and business structures, strategic decision-making, and processes of economic globalization and fragmentation. The book consists of two parts corresponding to the thematic symposium areas. The book content covers two sections: stable development in unstable world and globalization and fragmentation forces of the current world economy. The main topics included in the book are as follows: - Where is the world moving to and where is the economy in it? - Institutionalization of innovations. - Network architecture of economic relations. - Competences for the future. - Smart change management. - Monetary and fiscal policy development as a factor of economic modernization. - Role of international trade in the economy globalization. - Impact of globalization and economic fragmentation on the enterprise’s internal environment. - Financial conditions for entrepreneurship under the economic modernization. - Impact of scientific and technological progress on globalization and fragmentation of the economy.
Book Synopsis Anatomy and Physiology for Midwives E-Book by : Jane Coad
Download or read book Anatomy and Physiology for Midwives E-Book written by Jane Coad and published by Elsevier Health Sciences. This book was released on 2019-09-06 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a new edition of a highly popular text which presents the fascinating field of reproductive anatomy and physiology in a style which is perfect for student midwives. Presenting often complex information in an easy-to-understand manner, this useful volume builds up from the founding principles of human structure and function through to conception, embryological development and foetal growth, parturition and the transition to neonatal life. Fully updated throughout with the latest advances in the field, additional topics include sexual differentiation and behaviour, human genetics and genetic disorders, immunology, and maternal and infant nutrition. Containing over 200 line artworks to support the text, each chapter comes with Learning Outcome boxes, Case Studies, Key Points and Application to Practice boxes, all of which reinforce learning and help ‘bring the subject to life’. A well-established introduction to the science underpinning modern midwifery practice, Anatomy and Physiology for Midwives 4th edition will be ideal for all students of midwifery, including anyone returning to practice. Highly popular midwifery resource that explains the principles of reproductive A&P in an accessible and friendly manner Learning Objectives at the start of each chapter help readers structure their study time Case Studies ‘bring the subject to life’ and provide an opportunity to reflect on the implications for clinical practice Acknowledges the importance of underlying research and integrates theory and practice End of chapter Key Points and Application to Practice boxes further reinforce learning Helps midwives deal with questions from increasingly informed ‘parents to be’ More than 200 illustrations help clarify sometimes complex anatomical, physiological and clinical information New authorship brings additional expertise into the areas of cell physiology and research, particularly its clinical application to fertility and parturition An upgraded artwork program enhances the look and feel of the book Contains updates in the fast-moving field of reproductive physiology such as recent advances in fertility treatment, postnatal care of premature infants, and the impact of the gestational environment and early nutrition on later health Updated case studies reflect areas of advancing midwifery practice
Book Synopsis Civilizations development and species origin technologies by : Вадим Корпачев
Download or read book Civilizations development and species origin technologies written by Вадим Корпачев and published by Litres. This book was released on 2020-08-13 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin of life on Earth is the basic view of the world’s concept. At present, its origin and development are treated either from the scientific evolutionary theory points of view or religious mythological ones. At the same time, the evolutionary theory fails to provide grounded explanations to a lot of events which have happened and are observed in nature. The data related to the complexity of life processes genetic programming and many biology and palaeontological facts cast doubt on the possibility of spontaneous occurrence of protein organisms during evolutionary transformations. They indicate that the protein life development occurred in the direction of the planned improvement through the complex technology’s implementation which requires specific scientific knowledge. Therefore, the necessity to formulate the new technological concept of the life appearance on Earth which is provided by the given book has occurred. It summarizes numerous well-known facts which are being interpreted as the result of the highly developed civilization technological developments. The stated views have more grounds for existence than the evolutionary theory and biblical ideas about the divine creation of the world. The fact that society treats all the ideas of the life creation as religious ones and that they are used by the theologians turns out to be the ideological problem. The book is aimed at overcoming the barrier of such non-perception. The analysis performed allows the reader to understand in which cases random events occur, and in which ones there is a logical purposeful intelligent activity, the result of which is the development of self-replicating protein organisms programmed to perform the work necessary to meet the needs of their creators on Earth. Reflections on the possible material nature of the highly developed mind carriers are given.According to the author, a human being is not a passive observer of random evolutionary changes in nature, but has his mission in the artificially developed system of energy supply of Earth along with other protein organisms. If the protein world, including humans, has been created for a specific purpose, then mankind must not violate its implementation and should follow its mission. A new worldview should introduce changes in the main mankind’s activity spheres: science, politics, religion and the human being’s personal life.The book is designed for a wide range of readers of various specialties. Conceptually, it is important for people who do not share the evolutionary theory provisions and existing religious beliefs.
Download or read book The Genome War written by James Shreeve and published by Random House LLC. This book was released on 2005 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: An account of the race to solve the world's greatest scientific challenge--the sequencing of the human genome--describes the competition between rival researchers Craig Venter and Francis Collins.
Download or read book The Puzzle Solver written by Tracie White and published by Legacy Lit. This book was released on 2021-01-05 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Father, His Son, and an Unrelenting Quest for a Cure At the age of twenty-seven, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. Finally, even the sound of a footstep in his room became unbearable. The Puzzle Solver follows several years in which he desperately sought answers from specialist after specialist, where at one point his 6'3" frame dropped to 115 lbs. For years, he underwent endless medical tests, but doctors told him there was nothing wrong. Then, finally, a diagnosis: Chronic Fatigue Syndrome, also known as myalgic encephalomyelitis. In the 80s, when an outbreak of people immobilized by an indescribable fatigue were reported near Lake Tahoe, Nevada, doctors were at a loss to explain the symptoms. The condition would alternatively be nicknamed Raggedy Ann Syndrome or the Yuppie Disease, and there was no cure or answers about treatment. They were to remain sick. But there was one answer: Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition. In The Puzzle Solver, journalist Tracie White, who first wrote a viral and award-winning piece on Davis and his family in Stanford Medicine, tells his story. In gripping prose, she masterfully takes readers along on this journey with Davis to solve one of the greatest mysteries in medicine. In a piercing investigative narrative, closed doors are opened, and masked truths are exposed as Davis uncovers new proof confirming that Chronic Fatigue Syndrome is a biological disease. At the heart of this book is a moving story that goes far beyond medicine, this is a story about how the power of love -- and science -- can shine light in even the darkest, most hidden, corners of the world.
