The Molecular Control of Blood Cells

Download The Molecular Control of Blood Cells PDF Online Free

Author :
Publisher : Harvard University Press
ISBN 13 : 9780674581579
Total Pages : 182 pages
Book Rating : 4.5/5 (815 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Blood Cells by : Donald Metcalf

Download or read book The Molecular Control of Blood Cells written by Donald Metcalf and published by Harvard University Press. This book was released on 1988 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a masterful overview of the mechanics of blood cell formation and the factors that control blood cell growth. Cells circulating in the blood perform functions essential for the survival of organisms, yet blood cells and associated blood-cell-forming (hemopoietic) tissues have certain features that make them quite different from other vital organs in the body. These features include the short life span of mature blood cells, the multiplicity of blood cell types, and the wide dispersion of hemopoietic tissue in the body. The regulation of hemopoiesis in response to emergencies such as blood loss or infections is an exceedingly complex process. However, our knowledge of hemopoietic growth factors, known generally as colony-stimulating factors or CSFs, has made exciting advances in recent years. This book provides a leading authority's review of the purification and cloning of CSFs and their actions in regulating white blood cell production in the body. Donald Metcalf also examines the role of CSFs in controlling resistance to infections and in the initiation and suppression of myeloid leukemia. Metcalf's involvement at the center of this research from its inception to the present day enables him to give a historical view as well as a lucid summary of recent research. In addition, he addresses the broader question of the relation between growth control and cancer development. This excellent synopsis should be of particular interest to hematologists, virologists, general clinicians, and medical students.

The Molecular Control of Blood Cells

Download The Molecular Control of Blood Cells PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.:/5 (223 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Blood Cells by : Donald Metcalf

Download or read book The Molecular Control of Blood Cells written by Donald Metcalf and published by . This book was released on 1990 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of the Cell

Download Molecular Biology of the Cell PDF Online Free

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

DOWNLOAD NOW!


Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Control of Haemopoiesis

Download Molecular Control of Haemopoiesis PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470513896
Total Pages : 242 pages
Book Rating : 4.4/5 (75 download)

DOWNLOAD NOW!


Book Synopsis Molecular Control of Haemopoiesis by : Gregory R. Bock

Download or read book Molecular Control of Haemopoiesis written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The many different kinds of blood cells found in the human body are derived from multi-potential stem cells, which are induced to differentiate into one or another cell type by the action of regulatory proteins or growth factors. This volume looks at the way that binding of these proteins to specific receptors causes changes in gene expression in the nucleus and the activity of certain enzymes in the cytoplasm, committing the cell to a particular developmental pathway. Also discussed are recently established clinical applications and clinical trials of new techniques.

Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development

Download Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642451985
Total Pages : 414 pages
Book Rating : 4.6/5 (424 download)

DOWNLOAD NOW!


Book Synopsis Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development by : Constanze Bonifer

Download or read book Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development written by Constanze Bonifer and published by Springer Science & Business Media. This book was released on 2014-03-12 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never cause a problem again. In this book we will therefore make a journey from asking how more primitive organisms use the epigenetic regulatory machinery to balance growth with differentiation control towards digging deep into what controls the function of specialized cells of the human immune system. We will first discover that flies make blood but exist without blood vessels, why fish make blood cells in the kidney and which precise genetic circuitries are required for these developmental pathways. We will then learn the regulatory principles that drive the differentiation of mature blood cells from stem cells and what controls their function in mammals. In the process, we will find out what unites hematopoietic stem cells and endothelial cells. Finally, we will shed light on the molecular mechanisms that either alter hematopoietic cell differentiation or lead to the development of cells with impaired function.

Regulation of Tissue Oxygenation, Second Edition

Download Regulation of Tissue Oxygenation, Second Edition PDF Online Free

Author :
Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

DOWNLOAD NOW!


Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Molecular Control of Proliferation and Differentiation

Download Molecular Control of Proliferation and Differentiation PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0323158072
Total Pages : 279 pages
Book Rating : 4.3/5 (231 download)

DOWNLOAD NOW!


Book Synopsis Molecular Control of Proliferation and Differentiation by : John Papaconstantinou

Download or read book Molecular Control of Proliferation and Differentiation written by John Papaconstantinou and published by Elsevier. This book was released on 2012-12-02 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Control of Proliferation and Differentiation documents the proceedings of the 35th symposium of The Society for Developmental Biology entitled "Molecular Control of Proliferation and Differentiation," held at Asilomar, Monterey Peninsula, California, June 8-11, 1976. The contributions made by researchers at the symposium are organized into seven parts. Part I presents a paper on cell communication in embryological development. Part II includes studies on growth factors, including fibroblast growth factor and epidermal growth factor. Part III examines the factors affecting nerve cell differentiation and function. It includes papers on nerve growth factor and peptides as central nervous system neurotransmitters. Part IV focuses on cell interactions in blood cell development. It includes studies on factors affecting the differentiation of blood cells and the proliferation of hemopoietic stem cells in vitro. Part V examines cell interactions in the immune system. Part VI deals with cell interactions in organogenesis. Part VII covers the factors effecting differentiation in lower eukaryotes.

The Molecular Control of Cellular Activity

Download The Molecular Control of Cellular Activity PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 ( download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Cellular Activity by : John M. Allen

Download or read book The Molecular Control of Cellular Activity written by John M. Allen and published by . This book was released on 1962 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Molecular Control of Cellular Activity (Classic Reprint)

Download The Molecular Control of Cellular Activity (Classic Reprint) PDF Online Free

Author :
Publisher : Forgotten Books
ISBN 13 : 9780266933656
Total Pages : 340 pages
Book Rating : 4.9/5 (336 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Cellular Activity (Classic Reprint) by : John M. Allen

Download or read book The Molecular Control of Cellular Activity (Classic Reprint) written by John M. Allen and published by Forgotten Books. This book was released on 2017-10-29 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from The Molecular Control of Cellular Activity Accordingly, unless we follow through with the second step, the historian of the future will rightly blame us for partial blindness. This second step, which we have been slack in taking, is the study of the orderly interdependence of the partial mechanisms of the cell of which the identified molecules or particles are the tools. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Blood Groups and Red Cell Antigens

Download Blood Groups and Red Cell Antigens PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (225 download)

DOWNLOAD NOW!


Book Synopsis Blood Groups and Red Cell Antigens by : Laura Dean

Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cerebral Circulation

Download The Cerebral Circulation PDF Online Free

Author :
Publisher : Biota Publishing
ISBN 13 : 1615047239
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)

DOWNLOAD NOW!


Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

The Red Cell Life-Cycle From Erythropoiesis to Clearance

Download The Red Cell Life-Cycle From Erythropoiesis to Clearance PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889457028
Total Pages : 238 pages
Book Rating : 4.8/5 (894 download)

DOWNLOAD NOW!


Book Synopsis The Red Cell Life-Cycle From Erythropoiesis to Clearance by : Lars Kaestner

Download or read book The Red Cell Life-Cycle From Erythropoiesis to Clearance written by Lars Kaestner and published by Frontiers Media SA. This book was released on 2019-02-05 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen delivery under stress conditions such as exercising to the limit, diving or living in anaerobic aquatic habitats or at high altitude? Within the approximately 120 days (or 40 in a mouse, or 150-170 in a horse) life span of 'healthy' red blood cells, many cellular properties change leading to aged mixed cell populations in the circulation. Red blood cells seem to be genetically terminated by the time they become red blood cells and the contributions of this eBook increase the understanding of this process. There are surprisingly versatile remodeling processes happening during the red blood cell life span. Numerous disorders are associated with the premature onset of the 'ageing process' of red blood cells. Furthermore, in vitro ageing and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine. Many of the molecular mechanisms behind such effects are elucidated in this eBook.

The Molecular Basis of Blood Diseases

Download The Molecular Basis of Blood Diseases PDF Online Free

Author :
Publisher : Saunders
ISBN 13 :
Total Pages : 1080 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Basis of Blood Diseases by : George Stamatoyannopoulos

Download or read book The Molecular Basis of Blood Diseases written by George Stamatoyannopoulos and published by Saunders. This book was released on 2001 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: The superb Third Edition of this popular text covers all the recent groundbreaking developments which have taken place in this field. Comprehensively revised, it presents all the latest findings on the molecular bases of blood cell functions and disease mechanisms and the impact of these discoveries on the state of medicine. This edition includes new chapters such as signaling and antigen presentation by B-lymphocytes, molecular oncogenesis and more!

The Molecular Control of Cellular Activity

Download The Molecular Control of Cellular Activity PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (61 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Cellular Activity by : John M. Allen

Download or read book The Molecular Control of Cellular Activity written by John M. Allen and published by . This book was released on 1962 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Molecular Control of Cellular Activity

Download The Molecular Control of Cellular Activity PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

DOWNLOAD NOW!


Book Synopsis The Molecular Control of Cellular Activity by : J. M. Allen

Download or read book The Molecular Control of Cellular Activity written by J. M. Allen and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Control of Cellular Activity

Download Molecular Control of Cellular Activity PDF Online Free

Author :
Publisher : Hassell Street Press
ISBN 13 : 9781013833120
Total Pages : 222 pages
Book Rating : 4.8/5 (331 download)

DOWNLOAD NOW!


Book Synopsis Molecular Control of Cellular Activity by : John M Allen

Download or read book Molecular Control of Cellular Activity written by John M Allen and published by Hassell Street Press. This book was released on 2021-09-09 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Molecular Control of Cell Differentiation and Morphogenesis

Download Molecular Control of Cell Differentiation and Morphogenesis PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.:/5 (43 download)

DOWNLOAD NOW!


Book Synopsis Molecular Control of Cell Differentiation and Morphogenesis by : Gerhard D. Wassermann

Download or read book Molecular Control of Cell Differentiation and Morphogenesis written by Gerhard D. Wassermann and published by . This book was released on 1972 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: