Disorders of Sex Development

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Publisher : Springer Science & Business Media
ISBN 13 : 3642229646
Total Pages : 311 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Disorders of Sex Development by : John M. Hutson

Download or read book Disorders of Sex Development written by John M. Hutson and published by Springer Science & Business Media. This book was released on 2012-01-14 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.

The Molecular Basis of Sex and Differentiation

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Publisher : Springer Science & Business Media
ISBN 13 : 1461252601
Total Pages : 228 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The Molecular Basis of Sex and Differentiation by : Milton H. Saier

Download or read book The Molecular Basis of Sex and Differentiation written by Milton H. Saier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Man's mind stretched to a new idea never goes back to its original dimensions Oliver Wendell Holmes Our current understanding of sex and biological differentiation results from the application of three principal experimental approaches to these subjects: those of the physiologist, the biochemist, and the geneticist. These three approaches are illustrated by the materials presented in the chapters of this volume. Chapters 1-5 emphasize conceptualization of developmental processes, describing systems principally from the standpoint of the physiologist. Structures and functions are defined with only occasional reference to specific molecular details. Chapters 6- 10 present the views of the biochemist, attempting to describe functions influ encing or regulating cellular behavior at the molecular level. And Chapters 11- 14 illustrate the approaches of the modem-day geneticist in his attempts to gain a detailed understanding of processes controlling gene expression. While it is possible to delineate these three major sections, each emphasizing a distinct experimental approach, it must be realized that the yield of knowledge increases exponentially with the number of experimental approaches available to the investigator. Information resulting from the application of each of these approaches must converge to give the same answers for anyone biological phenomenon in anyone experimental system. Further, if we can learn of details regarding a particular process by applying different experimental approaches, our postulates concerning the underlying molecular mechanisms are likely to be more accurate. But biological systems are not unrelated.

Exploring the Biological Contributions to Human Health

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Publisher : National Academies Press
ISBN 13 : 0309132975
Total Pages : 287 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Genetics of Sex Differentiation

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Publisher : Elsevier
ISBN 13 : 0323158501
Total Pages : 268 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Genetics of Sex Differentiation by : Ursula Mittwoch

Download or read book Genetics of Sex Differentiation written by Ursula Mittwoch and published by Elsevier. This book was released on 2012-12-02 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics of Sex Differentiation intends to help readers understand the genetic basis of sex differentiation. The book focuses on explaining how the sex chromosomes affect the process of sex differentiation by influencing the rates at which cells divide. The book is composed of seven chapters. It provides overviews of classical genetics and structure of cells. It also explains the chromosomal basis of sex determination and sex determination using Drosophila. Polygenetics and continuous and quasicontinuous variations are also discussed. The book also discusses sex factors, determination, and disorders. Moreover, it explains the heterochromatin, embryological basis of sex differentiation, and triploidy and autosomal effects. In addition, it discusses the relationship of genes, chromosomes, growth, and sex. The book is an excellent ""bedside book"" for students in biology, specifically in genetics and developmental biology. Lecturers and professionals in biology and genetics will also find this book invaluable for their practice.

Sex Determination, Differentiation and Intersexuality in Placental Mammals

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521462181
Total Pages : 360 pages
Book Rating : 4.4/5 (621 download)

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Book Synopsis Sex Determination, Differentiation and Intersexuality in Placental Mammals by : R. H. F. Hunter

Download or read book Sex Determination, Differentiation and Intersexuality in Placental Mammals written by R. H. F. Hunter and published by Cambridge University Press. This book was released on 1995-03-09 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do males become male and females become female? And what are the consequences if the decision is not incisive? Drawing upon interests in animal genetics and molecular biology, the author endeavours to answer these difficult yet fascinating questions. Originally published in 1995, this book describes the genetic determination of sex and examines how sexual organs are differentiated. Using examples of intersexuality, chimaeras and asymmetries, the book describes the underlying molecular basis of sex determination and sexual differentiation, and focuses on the critical role of the rate of embryonic development in these vital processes. Male precocity is a recurrent theme, as is the involvement of Sertoli cells and their secretion of anti-Müllerian hormone. An invaluable book for reproductive physiologists, geneticists and developmental biologists whose interests may extend from animal science through veterinary medicine to human clinical medicine.

Molecular Genetics of Sex Determination

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Author :
Publisher : Academic Press
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Genetics of Sex Determination by : Stephen S. Wachtel

Download or read book Molecular Genetics of Sex Determination written by Stephen S. Wachtel and published by Academic Press. This book was released on 1994 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text is organized into two parts. Firstly, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial and Drosophila systems. Secondly, it covers current human genetics, clinical studies and the syndromes of abnormal sex differentiation.

The Genetics and Biology of Sex Determination

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470843468
Total Pages : 286 pages
Book Rating : 4.8/5 (434 download)

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Book Synopsis The Genetics and Biology of Sex Determination by : Derek J. Chadwick

Download or read book The Genetics and Biology of Sex Determination written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2002-04-26 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.

Genetic Markers of Sex Differentiation

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1489919651
Total Pages : 174 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Genetic Markers of Sex Differentiation by : Florence P. Haseltine

Download or read book Genetic Markers of Sex Differentiation written by Florence P. Haseltine and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Biology of Reproduction

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Publisher : Cambridge University Press
ISBN 13 : 1108499856
Total Pages : 491 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis The Biology of Reproduction by : Giuseppe Fusco

Download or read book The Biology of Reproduction written by Giuseppe Fusco and published by Cambridge University Press. This book was released on 2019-10-10 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: A look into the phenomena of sex and reproduction in all organisms, taking an innovative, unified and comprehensive approach.

Sex Control in Aquaculture

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Publisher : John Wiley & Sons
ISBN 13 : 1119127270
Total Pages : 1810 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Sex Control in Aquaculture by : Hanping Wang

Download or read book Sex Control in Aquaculture written by Hanping Wang and published by John Wiley & Sons. This book was released on 2018-11-08 with total page 1810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awarded Bookauthority's "Best Aquaculture Books of all Time" A comprehensive resource that covers all the aspects of sex control in aquaculture written by internationally-acclaimed scientists Comprehensive in scope, Sex Control in Aquaculture first explains the concepts and rationale for sex control in aquaculture, which serves different purposes. The most important are: to produce monosex stocks to rear only the fastest-growing sex in some species, to prevent precocious or uncontrolled reproduction in other species and to aid in broodstock management. The application of sex ratio manipulation for population control and invasive species management is also included. Next, this book provides detailed and updated information on the underlying genetic, epigenetic, endocrine and environmental mechanisms responsible for the establishment of the sexes, and explains chromosome set manipulation techniques, hybridization and the latest gene knockout approaches. Furthermore, the book offers detailed protocols and key summarizing information on how sex control is practiced worldwide in 35 major aquaculture species or groups, including fish and crustaceans, and puts the focus on its application in the aquaculture industry. With contributions from an international panel of leading scientists, Sex Control in Aquaculture will appeal to a large audience: aquaculture/fisheries professionals and students, scientists or biologists working with basic aspects of fish/shrimp biology, growth and reproductive endocrinology, genetics, molecular biology, evolutionary biology, and R&D managers and administrators. This text explores sex control technologies and monosex production of commercially-farmed fish and crustacean species that are highly in demand for aquaculture, to improve feed utilization efficiency, reduce energy consumption for reproduction and eliminate a series of problems caused by mixed sex rearing. Thus, this book: Contains contributions from an international panel of leading scientists and professionals in the field Provides comprehensive coverage of both established and new technologies to control sex ratios that are becoming more necessary to increase productivity in aquaculture Includes detailed coverage of the most effective sex control techniques used in the world's most important commercially-farmed species Sex Control in Aquaculture is the comprehensive resource for understanding the biological rationale, scientific principles and real-world practices in this exciting and expanding field.

The Molecular Basis of Sex and Differentiation

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis The Molecular Basis of Sex and Differentiation by : Milton H. Saier

Download or read book The Molecular Basis of Sex and Differentiation written by Milton H. Saier and published by Springer. This book was released on 1984-10-10 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Man's mind stretched to a new idea never goes back to its original dimensions Oliver Wendell Holmes Our current understanding of sex and biological differentiation results from the application of three principal experimental approaches to these subjects: those of the physiologist, the biochemist, and the geneticist. These three approaches are illustrated by the materials presented in the chapters of this volume. Chapters 1-5 emphasize conceptualization of developmental processes, describing systems principally from the standpoint of the physiologist. Structures and functions are defined with only occasional reference to specific molecular details. Chapters 6- 10 present the views of the biochemist, attempting to describe functions influ encing or regulating cellular behavior at the molecular level. And Chapters 11- 14 illustrate the approaches of the modem-day geneticist in his attempts to gain a detailed understanding of processes controlling gene expression. While it is possible to delineate these three major sections, each emphasizing a distinct experimental approach, it must be realized that the yield of knowledge increases exponentially with the number of experimental approaches available to the investigator. Information resulting from the application of each of these approaches must converge to give the same answers for anyone biological phenomenon in anyone experimental system. Further, if we can learn of details regarding a particular process by applying different experimental approaches, our postulates concerning the underlying molecular mechanisms are likely to be more accurate. But biological systems are not unrelated.

Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology: Proceedings of the 2nd World Conference

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441980024
Total Pages : 172 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology: Proceedings of the 2nd World Conference by : Maria I. New

Download or read book Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology: Proceedings of the 2nd World Conference written by Maria I. New and published by Springer Science & Business Media. This book was released on 2011-06-21 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 2nd World Conference – Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology. The meeting took place at The Eden Roc Hotel in Miami Beach, Florida, 1/15/10 – 1/17-10. Endocrinology and more specifically, the area of sexual differentiation disorders is an evolving field of medicine. The diagnosis and treatment of Disorders of Sex Development (DSD) is multi-faceted.

Temperature-Dependent Sex Determination in Vertebrates

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Publisher : Smithsonian Institution Scholarly Press
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Temperature-Dependent Sex Determination in Vertebrates by : Nicole Valenzuela

Download or read book Temperature-Dependent Sex Determination in Vertebrates written by Nicole Valenzuela and published by Smithsonian Institution Scholarly Press. This book was released on 2004 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by the world's foremost authorities on the subject, with essays by leading scholars in the field, this work shows how the sex of reptiles and many fish is determined not by the chromosomes they inherit but by the temperature at which incubation takes place.

Genetics of Sex Determination

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Publisher : Elsevier
ISBN 13 : 0080526179
Total Pages : 387 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Genetics of Sex Determination by : R.S. Verma

Download or read book Genetics of Sex Determination written by R.S. Verma and published by Elsevier. This book was released on 1996-04-23 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be true for some species but his suggestion could not take off the ground as gender in Drosophila is determined by the number of X chromosomes. Technical advances in molecular biology have revived the initial thinking of Fisher and dictate that TDF or SRY genes in humans or Tdy in mice are sex determining genes. The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, are quite bewildering traits that have caused much amazement concerning the pairing mechanism(s) of the pseudoautosomal regions of human X and Y chromosomes at meiosis. These findings have opened new avenues to explore further the genetic basis of sex determination at the single gene level.The aim of the fourth volume, titled Genetics of Sex Determination is to reflect on the latest advances and future investigative directions, encompassing 10 chapters. Commissioned several distinguished scientists, all pre-eminent authorities in each field to shed their thoughts concisely but epitomise their chapters with an extended bibliography. Obviously, during the past 60 years, the metoric advances are voluminous and to cover every account of genes, chromosomes, and sex in a single volume format would be a herculean task. Therefore, a few specific topics are chosen, which may be of great interest to scientists and clinicians. The seasoned scientists who love to inquire about the role of genes in sex determination should find the original work of these notable contributors very enlightening. This volume is intended for advanced students who want to keep abreast as well as for those who indulge in the search for genes of sex determination.

Endocrinology of the Testis and Male Reproduction

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Author :
Publisher : Springer
ISBN 13 : 9783319444406
Total Pages : 1364 pages
Book Rating : 4.4/5 (444 download)

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Book Synopsis Endocrinology of the Testis and Male Reproduction by : Manuela Simoni

Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Genetics of Sexual Differentiation and Sexually Dimorphic Behaviors

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Author :
Publisher : Elsevier
ISBN 13 : 0080551602
Total Pages : 287 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Genetics of Sexual Differentiation and Sexually Dimorphic Behaviors by : Daisuke Yamamoto

Download or read book Genetics of Sexual Differentiation and Sexually Dimorphic Behaviors written by Daisuke Yamamoto and published by Elsevier. This book was released on 2011-07-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Nine chapters on the most advanced research on the differentiating behaviors among sexes More than 300 pages of articles from leading international scientists, this volume offers genetic behaviorial information related to drosophila, mice, birds, voles, and mammals Hot topics include sex differences in brain and behavior; genomic imprinting and the evolution of sex differences; gene regulation; peptide pheromone production and reception, and more

Sex Chromosomes and Sex-Linked Genes

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642881785
Total Pages : 201 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Sex Chromosomes and Sex-Linked Genes by : Susumu Ohno

Download or read book Sex Chromosomes and Sex-Linked Genes written by Susumu Ohno and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural selection operates among individual organisms which differ in their genetic constitution. The degree of hereditary variability within a species is greatly enhanced by cross-fertilization. Indeed, the mechanism of sexual reproduction occurred very early in evolution, for it is seen today even in bacteria. In Escherichia coli, fertilization occurs by passage of the single chromosome from the male into the female bacterium (LEDERBERG, 1959). In multicellular organisms, the separation of germ from soma, and the production of haploid gametes became mandatory. The gametes were of two types. One, extremely mobile, was designed to seek out and penetrate the other, which loaded with nutrients, received the mobile gamete and intiated the development of a new individual. The foundation for true bisexuality was thus laid. In the primitive state of bisexuality, whether an individual is to be a sperm-producing male or an egg-producing female appears to be decided rather haphazardly. In the worm, Banelia viridis, the minute males are parasites in the female. Larvae that become attached to the proboscis of an adult female become males, while unattached larvae sink to the bottom and become females (BALTZER, 1935). The more sophisticated state of bisexuality was initiated by setting aside a particular pair of chromosomes for specialization and making either the male or the female a heterogametic sex. Sex chromosomes as we know them were thus born.