The Interaction of Synthetic Mono- and Dinuclear Metal Complexes with DNA, Especially in the Context of Left-handed Z-DNA

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ISBN 13 :
Total Pages : 193 pages
Book Rating : 4.:/5 (695 download)

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Book Synopsis The Interaction of Synthetic Mono- and Dinuclear Metal Complexes with DNA, Especially in the Context of Left-handed Z-DNA by : Bernhard Spingler

Download or read book The Interaction of Synthetic Mono- and Dinuclear Metal Complexes with DNA, Especially in the Context of Left-handed Z-DNA written by Bernhard Spingler and published by . This book was released on 2008 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metal Complex - DNA Interactions

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Publisher : John Wiley & Sons
ISBN 13 : 9781405194105
Total Pages : 544 pages
Book Rating : 4.1/5 (941 download)

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Book Synopsis Metal Complex - DNA Interactions by : Nick Hadjiliadis

Download or read book Metal Complex - DNA Interactions written by Nick Hadjiliadis and published by John Wiley & Sons. This book was released on 2009-03-30 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.

Synthesis of Dinuclear Metal Complexes and Their Interactions with DNA

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ISBN 13 :
Total Pages : 139 pages
Book Rating : 4.:/5 (637 download)

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Book Synopsis Synthesis of Dinuclear Metal Complexes and Their Interactions with DNA by : Alfredo Medina Molner

Download or read book Synthesis of Dinuclear Metal Complexes and Their Interactions with DNA written by Alfredo Medina Molner and published by . This book was released on 2007 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interactions of Dinuclear Transition Metal Compounds with DNA Nucleobases and Related Nitrogen Donor Ligands

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ISBN 13 :
Total Pages : 468 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Interactions of Dinuclear Transition Metal Compounds with DNA Nucleobases and Related Nitrogen Donor Ligands by : Kemal V. Catalan

Download or read book Interactions of Dinuclear Transition Metal Compounds with DNA Nucleobases and Related Nitrogen Donor Ligands written by Kemal V. Catalan and published by . This book was released on 1999 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interactions of Dinuclear Transition Metal Complexes with Amino Acids, Nucleotides, and DNA

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Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Interactions of Dinuclear Transition Metal Complexes with Amino Acids, Nucleotides, and DNA by : Jennifer Simone Hess

Download or read book Interactions of Dinuclear Transition Metal Complexes with Amino Acids, Nucleotides, and DNA written by Jennifer Simone Hess and published by . This book was released on 1998 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hard and Soft Acids and Bases

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Publisher : Hutchinson Ross Publishing Company
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Hard and Soft Acids and Bases by : Ralph G. Pearson

Download or read book Hard and Soft Acids and Bases written by Ralph G. Pearson and published by Hutchinson Ross Publishing Company. This book was released on 1973 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anion Sensing

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540232476
Total Pages : 252 pages
Book Rating : 4.2/5 (324 download)

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Book Synopsis Anion Sensing by : Eric V. Anslyn

Download or read book Anion Sensing written by Eric V. Anslyn and published by Springer Science & Business Media. This book was released on 2005-05-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts

Bioinorganic Photochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9781405193276
Total Pages : 398 pages
Book Rating : 4.1/5 (932 download)

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Book Synopsis Bioinorganic Photochemistry by : Grazyna Stochel

Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.

Polymer Synthesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540217114
Total Pages : 228 pages
Book Rating : 4.2/5 (171 download)

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Book Synopsis Polymer Synthesis by :

Download or read book Polymer Synthesis written by and published by Springer Science & Business Media. This book was released on 2004-10-08 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. T. Takata, N. Kihara, Y. Furusho: Polyrotaxanes and Polycatenanes: Recent Advances in Syntheses and Applications of Polymers Comprising of Interlocked Structures.- 2. M. Suginome, Y. Ito: Transition Metal-Mediated Polymerization of Isocyanides.- 3. K. Osakada, D. Takeuchi: Coordination Polymerization of Dienes, Allenes and Methylenecycloalkanes.

Platinum-Based Drugs in Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Platinum-Based Drugs in Cancer Therapy by : Lloyd R. Kelland

Download or read book Platinum-Based Drugs in Cancer Therapy written by Lloyd R. Kelland and published by Springer Science & Business Media. This book was released on 2000 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs.

Dynamic Combinatorial Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9783527629718
Total Pages : 211 pages
Book Rating : 4.6/5 (297 download)

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Book Synopsis Dynamic Combinatorial Chemistry by : Joost N. H. Reek

Download or read book Dynamic Combinatorial Chemistry written by Joost N. H. Reek and published by John Wiley & Sons. This book was released on 2010-02-02 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This long-awaited first book on this exciting new field in organic and supramolecular chemistry explains the fundamentals as well as possible applications of DCC. Authored by the "Who's Who" of DCC it spans the whole range of topics: catalysts, sensors, polymers, ligands, receptors, concluding with a look at future developments and perspectives. All set to become the standard text in the field, this one-stop reference contains everything organic, catalytic, polymer, physical and biochemists need to know.

Artificial Nucleases

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540201120
Total Pages : 330 pages
Book Rating : 4.2/5 (11 download)

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Book Synopsis Artificial Nucleases by : Marina A. Zenkova

Download or read book Artificial Nucleases written by Marina A. Zenkova and published by Springer Science & Business Media. This book was released on 2004-01-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.

Organic Ligands in Marine Trace Metal Biogeochemistry

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Publisher : Frontiers Media SA
ISBN 13 : 2889453766
Total Pages : 305 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Organic Ligands in Marine Trace Metal Biogeochemistry by : Kristen N. Buck

Download or read book Organic Ligands in Marine Trace Metal Biogeochemistry written by Kristen N. Buck and published by Frontiers Media SA. This book was released on 2018-01-11 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research topic highlights the most recent accomplishments of a Scientific Committee on Oceanic Research (SCOR) Working Group, SCOR WG 139: Organic Ligands - A Key Control on Trace Metal Biogeochemistry in the Ocean.

Drug-DNA Interactions

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Publisher : John Wiley & Sons
ISBN 13 : 0470369167
Total Pages : 475 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Drug-DNA Interactions by : Kazuo Nakamoto

Download or read book Drug-DNA Interactions written by Kazuo Nakamoto and published by John Wiley & Sons. This book was released on 2008-09-08 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy.

Materials Nanoarchitectonics

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Publisher : Elsevier
ISBN 13 : 0323994733
Total Pages : 648 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Materials Nanoarchitectonics by : Katsuhiko Ariga

Download or read book Materials Nanoarchitectonics written by Katsuhiko Ariga and published by Elsevier. This book was released on 2023-12-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials Nanoarchitectonics: From Integrated Molecular Systems to Advanced Devices provides the latest information on the design and molecular manipulation of self-organized hierarchically structured systems using tailor-made nanoscale materials as structural and functional units. The book is organized into three main sections that focus on molecular design of building blocks and hybrid materials, formation of nanostructures, and applications and devices. Bringing together emerging materials, synthetic aspects, nanostructure strategies, and applications, the book aims to support further progress, by offering different perspectives and a strong interdisciplinary approach to this rapidly growing area of innovation. This is an extremely valuable resource for researchers, advanced students, and scientists in industry, with an interest in nanoarchitectonics, nanostructures, and nanomaterials, or across the areas of nanotechnology, chemistry, surface science, polymer science, electrical engineering, physics, chemical engineering, and materials science. Offers a nanoarchitectonic perspective on emerging fields, such as metal-organic frameworks, porous polymer materials, or biomimetic nanostructures Discusses different approaches to utilizing "soft chemistry" as a source for hierarchically organized materials Offers an interdisciplinary approach to the design and construction of integrated chemical nano systems Discusses novel approaches towards the creation of complex multiscale architectures

Metal Nanoparticles in Microbiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642183123
Total Pages : 306 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Metal Nanoparticles in Microbiology by : Mahendra Rai

Download or read book Metal Nanoparticles in Microbiology written by Mahendra Rai and published by Springer Science & Business Media. This book was released on 2011-04-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Metal-Organic Frameworks

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Publisher : John Wiley & Sons
ISBN 13 : 111803516X
Total Pages : 440 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Metal-Organic Frameworks by : Leonard R. MacGillivray

Download or read book Metal-Organic Frameworks written by Leonard R. MacGillivray and published by John Wiley & Sons. This book was released on 2010-12-17 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-organic frameworks represent a new class of materials that may solve the hydrogen storage problem associated with hydrogen-fueled vehicles. In this first definitive guide to metal-organic framework chemistry, author L. MacGillivray addresses state-of-art developments in this promising technology for alternative fuels. Providing professors, graduate and undergraduate students, structural chemists, physical chemists, and chemical engineers with a historical perspective, as well as the most up-to-date developments by leading experts, Metal-Organic Frameworks examines structure, symmetry, supramolecular chemistry, surface engineering, metal-organometallic frameworks, properties, and reactions.