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The Immunology Of Adverse Drug Reactions
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Book Synopsis Adverse Drug Reactions by : Jack Uetrecht
Download or read book Adverse Drug Reactions written by Jack Uetrecht and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.
Author :Werner J. Pichler Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805582692 Total Pages :440 pages Book Rating :4.8/5 (55 download)
Book Synopsis Drug Hypersensitivity by : Werner J. Pichler
Download or read book Drug Hypersensitivity written by Werner J. Pichler and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approaches the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in this book. The book also covers clinical manifestations and new diagnostic methods, and introduces some recetly established animal models. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced.
Book Synopsis Drug Allergy Testing by : David Khan
Download or read book Drug Allergy Testing written by David Khan and published by Elsevier Health Sciences. This book was released on 2017-07-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. - Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. - Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.
Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine
Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Download or read book Drug Allergy written by Brian A. Baldo and published by Springer. This book was released on 2016-05-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine. Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, diagnoses, underlying mechanisms and structure-activity relationships. Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs. In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in science and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.
Book Synopsis Pediatric Allergy: Principles and Practice E-Book by : Donald Y. M. Leung
Download or read book Pediatric Allergy: Principles and Practice E-Book written by Donald Y. M. Leung and published by Elsevier Health Sciences. This book was released on 2010-10-13 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.
Book Synopsis Meyler's Side Effects of Drugs by : Jeffrey K. Aronson
Download or read book Meyler's Side Effects of Drugs written by Jeffrey K. Aronson and published by Elsevier. This book was released on 2015-10-15 with total page 7629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company
Book Synopsis The Immunology of Adverse Drug Reactions by : Patricia Illing
Download or read book The Immunology of Adverse Drug Reactions written by Patricia Illing and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mann's Pharmacovigilance by : Elizabeth B. Andrews
Download or read book Mann's Pharmacovigilance written by Elizabeth B. Andrews and published by John Wiley & Sons. This book was released on 2014-03-24 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly Commended at the BMA Medical Book Awards 2015 Mann’s Pharmacovigilance is the definitive reference for the science of detection, assessment, understanding and prevention of the adverse effects of medicines, including vaccines and biologics. Pharmacovigilance is increasingly important in improving drug safety for patients and reducing risk within the practice of pharmaceutical medicine. This new third edition covers the regulatory basis and the practice of pharmacovigilance and spontaneous adverse event reporting throughout the world. It examines signal detection and analysis, including the use of population-based databases and pharmacoepidemiological methodologies to proactively monitor for and assess safety signals. It includes chapters on drug safety practice in specific organ classes, special populations and special products, and new developments in the field. From an international team of expert editors and contributors, Mann’s Pharmacovigilance is a reference for everyone working within pharmaceutical companies, contract research organisations and medicine regulatory agencies, and for all researchers and students of pharmaceutical medicine. The book has been renamed in honor of Professor Ronald Mann, whose vision and leadership brought the first two editions into being, and who dedicated his long career to improving the safety and safe use of medicines.
Book Synopsis Clinical Aspects of Immunology by : D. K. Peters
Download or read book Clinical Aspects of Immunology written by D. K. Peters and published by Wiley-Blackwell. This book was released on 1992-12-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dermatology in Public Health Environments by : Renan Rangel Bonamigo
Download or read book Dermatology in Public Health Environments written by Renan Rangel Bonamigo and published by Springer. This book was released on 2018-01-26 with total page 1581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a reference guide in the field of dermatology, presenting and discussing its interface with public health. Dermatological diseases are extremely common in populations around the globe, and the systematization of knowledge about these dermatoses and their relationships with different epidemiological factors may help us to understand the challenges that governments and private institutions face and must try to overcome in order to improve global health. Undergraduate and graduate students, dermatologists and general practitioners who study and / or work in the area will find scientific support in this book, which is intended as a reference work for dermatological practice and public health. The book has ten sections addressing carefully selected topics, including: 1. concepts in dermatoepidemiology and the international strategies in programs of Public Health; 2-6. the most significant skin diseases (including dermatology in tropical medicine) ; 7. diseases that are not primarily dermatological, but have a high impact on public health and may have skin and mucosal manifestations; 8. a number of emerging issues in dermatology in public health; 9. clinical approaches (diagnosis and management) to common dermatological symptoms and 10. multidisciplinary approaches in dermatology. The editors have brought together authors with extensive experience in their respective fields in order to provide a reference book for those involved in or with an interest in the relationship between dermatology and public health.
Download or read book Food Allergy written by Dean D. Metcalfe and published by John Wiley & Sons. This book was released on 2011-08-31 with total page 1125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying a scientific approach this unique book covers both pediatric and adult adverse reactions to foods and food additives. Following the successful formula of the previous editions, Food Allergy has established itself asthe comprehensive reference for those treating patients with food allergy or suspected allergy. The book has been thoroughly revised and updated presenting new chapters devoted to food biotechnology and genetic engineering, seafood toxins, future approaches to therapy and hidden food allergens. Food Allergy, fourth edition, is divided into five sections featuring key concept boxes for each chapter. Displayed in a logical manner the book is a practical, readable reference for use in the hospital or private practice setting.
Book Synopsis Vaccines and Autoimmunity by : Yehuda Shoenfeld
Download or read book Vaccines and Autoimmunity written by Yehuda Shoenfeld and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
Book Synopsis Oxford Handbook of Clinical Pharmacy by : Phil Wiffen
Download or read book Oxford Handbook of Clinical Pharmacy written by Phil Wiffen and published by Oxford University Press, USA. This book was released on 2012-01-26 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the definitive quick reference guide to clinical pharmacy, providing practising and student pharmacists with a wealth of practical information.
Download or read book Middleton's Allergy written by and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge.
Book Synopsis Adverse Effects of Pertussis and Rubella Vaccines by : Institute of Medicine
Download or read book Adverse Effects of Pertussis and Rubella Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.
Book Synopsis Allergic Reactions to Drugs by : Meta Alexander
Download or read book Allergic Reactions to Drugs written by Meta Alexander and published by Springer. This book was released on 1983 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs. The main reasons for this state of affairs may be on the one hand that until a few years ago the pathophysiological mechanisms of the various types of allergic reactions were not well understood, and on the other hand that objective diagnosis of a drug allergy is still fraught with serious difficulties. Drug allergy is still an unpopular topic for most allergologists and pharmacologists; this is reflected by the fact that despite their frequency, allergic reactions to drugs still occupy a relatively small proportion of space in most pharmacology handbooks and in classical books devoted to the side effects of drugs. There has recently been considerable progress in research into the immunologi cal and pathophysiological events occurring in allergic reactions, and on that basis investigations of various drug allergies have also yield̃d new objective findings. Consequently, it was natural to attempt a review of the most frequent and important drug allergies in the form of a handbook. We originally intended to present a comprehensive review of all drug allergies, but the realization of this goal soon became more difficult than we had at first imagined.
