Platelets in Thrombotic and Non-Thrombotic Disorders

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Author :
Publisher : Springer
ISBN 13 : 3319474626
Total Pages : 1402 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Platelets in Thrombotic and Non-Thrombotic Disorders by : Paolo Gresele

Download or read book Platelets in Thrombotic and Non-Thrombotic Disorders written by Paolo Gresele and published by Springer. This book was released on 2017-03-08 with total page 1402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

The Immunological Role of Platelet Activation in the Pathophysiology of COVID-19

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832536603
Total Pages : 112 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Immunological Role of Platelet Activation in the Pathophysiology of COVID-19 by : Theresa Marie Rossouw

Download or read book The Immunological Role of Platelet Activation in the Pathophysiology of COVID-19 written by Theresa Marie Rossouw and published by Frontiers Media SA. This book was released on 2023-11-02 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are increasingly recognized for their role as mediators of immune response and inflammation. As major components of the hematological system, they form an important bridge between immunity and coagulation. In the context of viral infections, platelets may suppress viral dissemination but can also support viral persistence. When platelets become hyperactivated in response to an infection, patients can develop immuno-thrombosis and coagulopathy. These derangements of hemostasis are particularly relevant in the context of infection with the novel coronavirus, SARS-CoV-2, and the subsequent development of coronavirus disease, COVID-19, a disease in which thromboembolic events are an important cause of morbidity and mortality.

Heparin-Induced Thrombocytopenia

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Author :
Publisher : CRC Press
ISBN 13 : 0824758846
Total Pages : 660 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Heparin-Induced Thrombocytopenia by : Theodore Warkentin

Download or read book Heparin-Induced Thrombocytopenia written by Theodore Warkentin and published by CRC Press. This book was released on 2003-12-05 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin

Platelet Heterogeneity

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1447117638
Total Pages : 276 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Platelet Heterogeneity by : John Martin

Download or read book Platelet Heterogeneity written by John Martin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Battle is a practical and sometimes lasting way of solving man's problems. It relies on the strength of the combatants and ignores the truth of the dispute. Discussion face to face can dissolve attitudes which have incorrectly determined judgements. The most striking example of this that I know is a Battle in Ireland in the eleventh century, where the king of Leinster fought a Viking prince. The Icelanders had raided Ireland for several generations in search of women, which they lacked since most of the population of Iceland were men who had arrived there by rowing long-boats from Norway. The prince was leading such a raid for the first time. Standing in the prow of the leading boat he saw Irish cavalry galloping along the beach to meet them. As they approached the shore the Irish king rode out of the band to challenge single combat. The Icelander jumped into the surf to meet him. As they raised their swords each realized that the other's face was like his own. When the Irish king spoke the other recognized the language. It had been spoken in Iceland by his grandmother who had been captured and taken there from Ireland. Swords were dropped and replaced by drinking horns. It was soon established that they were cousins. The battle gave way to a life-time of close co-operation.

Mitochondrial Dysfunction

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Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Trauma Induced Coagulopathy

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Publisher : Springer Nature
ISBN 13 : 3030536068
Total Pages : 802 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Trauma Induced Coagulopathy by : Hunter B. Moore

Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

Anticoagulants, Antiplatelets, and Thrombolytics

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Author :
Publisher : Humana
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Anticoagulants, Antiplatelets, and Thrombolytics by : Shaker A. Mousa

Download or read book Anticoagulants, Antiplatelets, and Thrombolytics written by Shaker A. Mousa and published by Humana. This book was released on 2010-08-17 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular BiologyTM series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.

Neurodegeneration in Multiple Sclerosis

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Publisher : Springer Science & Business Media
ISBN 13 : 8847003911
Total Pages : 233 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Neurodegeneration in Multiple Sclerosis by : M. Filippi

Download or read book Neurodegeneration in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field. The context in which this book exists is that there is an increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information.

Sickle Cell Anemia

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Publisher : Springer
ISBN 13 : 3319067133
Total Pages : 439 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Sickle Cell Anemia by : Fernando Ferreira Costa

Download or read book Sickle Cell Anemia written by Fernando Ferreira Costa and published by Springer. This book was released on 2016-03-29 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.

Hematology

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Publisher : Elsevier Health Sciences
ISBN 13 : 1416030069
Total Pages : 836 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Hematology by : Bernadette F. Rodak

Download or read book Hematology written by Bernadette F. Rodak and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook explores key aspects of hematology from normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origin. Includes a revised section on hemostasis and thrombosis. Case studies and chapter summaries are included.

Immunoregulation

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Publisher : Springer Science & Business Media
ISBN 13 : 1468445472
Total Pages : 473 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunoregulation by : Nicola Fabris

Download or read book Immunoregulation written by Nicola Fabris and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.

The Philosophical Disenfranchisement of Art

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Author :
Publisher : Columbia University Press
ISBN 13 : 9780231132275
Total Pages : 254 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis The Philosophical Disenfranchisement of Art by : Arthur C. Danto

Download or read book The Philosophical Disenfranchisement of Art written by Arthur C. Danto and published by Columbia University Press. This book was released on 2005 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this text, first published in 1986, the author explored the inextricably linked but often misunderstood relationship between art and philosophy. In this new edition, Jonathan Gilmore provides a foreword discussing how scholarship has changed in response to it.

Liver Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 331902096X
Total Pages : 482 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Liver Immunology by : M. Eric Gershwin

Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.

Identification, function and mechanisms of interferon induced genes associated with viruses

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832514693
Total Pages : 157 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identification, function and mechanisms of interferon induced genes associated with viruses by : Chang Li

Download or read book Identification, function and mechanisms of interferon induced genes associated with viruses written by Chang Li and published by Frontiers Media SA. This book was released on 2023-02-15 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mast Cells and Basophils

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Publisher : Academic Press
ISBN 13 : 0080535852
Total Pages : 738 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Mast Cells and Basophils by : Gianni Marone

Download or read book Mast Cells and Basophils written by Gianni Marone and published by Academic Press. This book was released on 2000-05-25 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Immunology for Engineers

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Author :
Publisher : Elsevier
ISBN 13 : 0443193517
Total Pages : 580 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Immunology for Engineers by :

Download or read book Immunology for Engineers written by and published by Elsevier. This book was released on 2024-05-17 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy. - Presents the latest in immunological engineering - Delves into timely topics such as antibody engineering - Covers vaccine engineering amongst many other important topics

The Circulating Platelet

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Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Circulating Platelet by : Louis M. Aledort

Download or read book The Circulating Platelet written by Louis M. Aledort and published by . This book was released on 1971 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: