The Immunity Of The Human Foetus And Newborn Infant

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The Immunity of the Human Foetus and Newborn Infant

Author : Ivo Miler
Publisher : Springer
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Immunity of the Human Foetus and Newborn Infant by : Ivo Miler

Download or read book The Immunity of the Human Foetus and Newborn Infant written by Ivo Miler and published by Springer. This book was released on 1983 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: 7 Introduction - what is ontogenesis? 9 Ontogenesis of immunity of the human foetus 12 Development of the cellular substrate of the immune system . . . . . . . 13 Development of the lymphatic system . . . . . . . . . . . . . . . . 14 Synthesis of immunologically active proteins - the complement components and immunoglobulins - in the foetal period 18 Complement components. . . . . . . . . . . . . 18 Immunoglobulin synthesis . . . . . . . . . . . . 23 B lymphocytes with surface membrane immunoglobulins 26 Transmission of antibodies ami immunoglobulins from mother to foetus 29 Transplacental transmission of specific antibodies . . . . . . . * 29 Transplacental transmission of immunoglobulins . . . . . . . . . 33 Physiological conditions for the transmission of immunoglobulins from mother to foetus . . . . . . . . . . . . . . . . . . . . . . . . . 36 Mechanism of transplacental transmission of IgG . . . . . . . . . . 39 Role of the Fc fragment of the IgG molecule and of cell receptors in the transplacental transmission of IgG . . . . . 42 Antibacterial mechanisms of the amniotic fluid . . . . . . . . . . . . 45 Ontogenesis of the foetus's cellular immunity . . . . . . . . . . . . 47 Incidence in the foetus of T lymphocytes forming spontaneous E rosettes 48 Functional activity of the T cell system . . . . . . . . . . . . . . . 49 Response offoetallymphocytes to phytohaemagglutinin (PHA) stimulation in vitro . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Proliferative response of foetal lymphocytes to stimulation by allogenic cells in mi. xed lymphocyte cultures . . . . . . . . . . . . . . . . 51 Effector activity of foetal lymphocytes - cytotoxicity . . . . . . . . 52 Chronological survey of the commencement of foetal immunocompetence 53 Immunity of the physiological neonate Natural (nonspecific) neonatal immunity . , . . . . . . . . . . . . . 61 Cellular factors of natural neonatal immunity. The function of poly morp- nuclear (PMN) leucocytes - the inflammatory reaction . . . . .

Immunity in Compromised Newborns

Author : Per T. Sangild
Publisher : Frontiers Media SA
ISBN 13 : 2889713148
Total Pages : 393 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Immunity in Compromised Newborns by : Per T. Sangild

Download or read book Immunity in Compromised Newborns written by Per T. Sangild and published by Frontiers Media SA. This book was released on 2021-09-14 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neonatal Hematology

Author : Pedro A. de Alarcón
Publisher : Cambridge University Press
ISBN 13 : 1108488986
Total Pages : 501 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Neonatal Hematology by : Pedro A. de Alarcón

Download or read book Neonatal Hematology written by Pedro A. de Alarcón and published by Cambridge University Press. This book was released on 2021-02-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Infectious Diseases of the Fetus and Newborn E-Book

Author : Jack S. Remington
Publisher : Elsevier Health Sciences
ISBN 13 : 1437736378
Total Pages : 1275 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Infectious Diseases of the Fetus and Newborn E-Book by : Jack S. Remington

Download or read book Infectious Diseases of the Fetus and Newborn E-Book written by Jack S. Remington and published by Elsevier Health Sciences. This book was released on 2010-08-27 with total page 1275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Get the latest information on maternal infections when they are pertinent to the infant or developing fetus, including disease transmission through breastfeeding Diagnose, prevent, and treat neonatal infectious diseases with expert guidance from the world's leading authorities and evidence-based recommendations. Incorporate the latest findings about infections found in utero, during delivery, and in the neonatal period. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format Get fresh perspectives from two new associate editors—Drs. Yvonne Maldonado, head of the Pediatric Infectious Disease program at Stanford, and Victor Nizet, Professor of Pediatrics & Pharmacy at University of California, San Diego and UCSD School of Medicine. Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome the clinical challenges in developing countries where access to proper medical care is limited. Apply the latest recommendations for H1N1 virus and vaccines. Identify and treat infections with the latest evidence-based information on fighting life-threatening diseases in the fetus and newborn infants.

Immunology of the Neonate

Author : G.Roberto Burgio
Publisher : Springer Science & Business Media
ISBN 13 : 3642710948
Total Pages : 304 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Immunology of the Neonate by : G.Roberto Burgio

Download or read book Immunology of the Neonate written by G.Roberto Burgio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few years, many new observations have profoundly changed our concepts of the immune competence of the newborn. For the immune system, as for other systems and functions, the neonatal age represents a crucial transition period. In fact the immune characteristics of the fetus are likely to result fro- or be conditioned by - several often contradictory physiological requirements. On the one hand, it would certainly be an advantage for the fetus to acquire a complete immunocompetence as soon as possible in order to be able to cope with the eventual transplacental passage of pathogenic microorganisms and possibly also in order to reject maternal cells occasionally crossing the placental nd barrier. This is actually what occurs, at least in part, during the 2 and Jfd month of gestation when the fetus begins to acquire his biological individuality and at the same time the role of a "biological ego" resulting from the attain ment by the immune system of the capacity to discriminate between self and nonself.

Neonatal Immunity

Author : Constantin Bona
Publisher : Springer Science & Business Media
ISBN 13 : 1592598250
Total Pages : 389 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Neonatal Immunity by : Constantin Bona

Download or read book Neonatal Immunity written by Constantin Bona and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens.

Immunological Aspects of Infection in the Fetus and Newborn

Author : Harold P. Lambert
Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Immunological Aspects of Infection in the Fetus and Newborn by : Harold P. Lambert

Download or read book Immunological Aspects of Infection in the Fetus and Newborn written by Harold P. Lambert and published by . This book was released on 1981 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Infectious Diseases of the Fetus and Newborn Infant

Author : Jack S. Remington
Publisher : W.B. Saunders Company
ISBN 13 :
Total Pages : 1264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Infectious Diseases of the Fetus and Newborn Infant by : Jack S. Remington

Download or read book Infectious Diseases of the Fetus and Newborn Infant written by Jack S. Remington and published by W.B. Saunders Company. This book was released on 1983 with total page 1264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Neonatal Immune System: A Unique Host-Microbial Interface

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis The Neonatal Immune System: A Unique Host-Microbial Interface by :

Download or read book The Neonatal Immune System: A Unique Host-Microbial Interface written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging from the protective environment of the uterus, the newborn is exposed to a myriad of microbes, and quickly establishes a complex microbiome that shapes the infant's biology in ways that are only now beginning to come to light. Among these exposures are a number of potential pathogens. The host responses to these pathogens in the neonatal period are unique, reflecting a developing immune system even with delivery at term. Preterm infants are delivered at a time when host defense mechanisms are even less developed and therefore face additional risk. As such, the organisms that cause disease in this period are different from the pathogens that are common in other age groups, or the disease they cause manifests in more severe fashion. Developmental alterations in both innate and adaptive immune responses in neonates have been documented among many cell types and pathways over the last several decades. Contemporary insights into the human immune system and methodologies that allow an "omics" approach to these questions have continued to provide new information regarding the mechanisms that underlie the human neonate as an "immunocompromised host." This Research Topic highlights studies related to this unique host-pathogen interface. Contributions include those related to the innate or adaptive immune system of neonates, their response to microbial colonization or infection, and/or the pathogenesis of microbes causing disease in neonates.

Host Defenses in the Human Neonate

Author : Michael E. Miller
Publisher : Saunders
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Host Defenses in the Human Neonate by : Michael E. Miller

Download or read book Host Defenses in the Human Neonate written by Michael E. Miller and published by Saunders. This book was released on 1978 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immune Regulation

Author : Marc Feldmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461249961
Total Pages : 384 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Immune Regulation by : Marc Feldmann

Download or read book Immune Regulation written by Marc Feldmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There is strong evidence of the widening horizons of immunology, both technically, with the obviously major impact of molecular biology into our understanding of cellular processes, and also conceptually. Traditionally, the 'proceedings' of these conferences have been published. But have the books produced really recorded the major part of the conference, the informal, friendly, but intense and some times heated exchanges that take place between workers in tackling very similar problems and systems and which are at the heart of every successful conference? Unfortunately this essence cannot be incorpo rated by soliciting manuscripts. For this reason, we have changed the format of publication, retaining published versions of the symposium papers, but requesting the workshop chairmen to produce a summary of the major new observations and areas of controversy highlighted in their sessions, as a vehicle for defining current areas of interest and debate. Not an easy task, as the workshop topics were culled from the abstracts submitted by the participants, rather than being on predefined topics. The unseasonal warmth in Cambridge was reflected in the atmos phere of the conference, the organization of which benefited from the administrative skills of Jean Bacon, Philippa Wells, Mr. Peter Irving, and Mrs.

The Physiology of the Newborn Infant

Author : Clement Andrew Smith
Publisher :
ISBN 13 :
Total Pages : 522 pages
Book Rating : 4.:/5 (38 download)

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Book Synopsis The Physiology of the Newborn Infant by : Clement Andrew Smith

Download or read book The Physiology of the Newborn Infant written by Clement Andrew Smith and published by . This book was released on 1959 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Maternal Immunization

Author : Elke Leuridan
Publisher : Academic Press
ISBN 13 : 0128145838
Total Pages : 394 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Maternal Immunization by : Elke Leuridan

Download or read book Maternal Immunization written by Elke Leuridan and published by Academic Press. This book was released on 2019-11-26 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines. Provides an overview of a quickly evolving topic. This will benefit the reader who wishes to rapidly become informed and up-to-date with new developments in this field Suitable to a broad audience: scientific researchers, obstetricians, gynecologists, neonatologists, vaccinators, pediatricians, students, and industry. Maternal vaccination impacts a wide range of specialists Allows health care professionals/researchers to gain insight into other aspects of vaccination in pregnancy outside of their specialism Is coauthored by specialists from multiple disciplines, providing a diverse view of the subject, increasing its interest and appeal Creates awareness of the current developments in this area of medicine and of the potential of maternal vaccination to improve the health of mothers and infants worldwide

Preterm Birth

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030910159X
Total Pages : 791 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Preterm Birth by : Institute of Medicine

Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.

Baby Medical School: Vaccines

Author : Cara Florance
Publisher : Sourcebooks Jabberwocky
ISBN 13 : 9781492694007
Total Pages : 24 pages
Book Rating : 4.6/5 (94 download)

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Book Synopsis Baby Medical School: Vaccines by : Cara Florance

Download or read book Baby Medical School: Vaccines written by Cara Florance and published by Sourcebooks Jabberwocky. This book was released on 2020-03-15 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: The popular Baby University series has now expanded into Baby Medical School! Inside your body, you have a lot of little helpers that work together to keep you healthy. And vaccines are super helpers that make your immune system even stronger! But how? And with what? Let's find out! Written by experts, the whimsical artwork and humorous text is perfect for enlightening the next generation of geniuses and creating a love for science they will carry for a lifetime! Empower children with knowledge so they can visit the doctor with courage and curiosity!

Immunologic Disorders in Infants and Children

Author : E. Richard Stiehm
Publisher : W.B. Saunders Company
ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunologic Disorders in Infants and Children by : E. Richard Stiehm

Download or read book Immunologic Disorders in Infants and Children written by E. Richard Stiehm and published by W.B. Saunders Company. This book was released on 1980 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunity and Inflammation in Health and Disease

Author : Shampa Chatterjee
Publisher : Academic Press
ISBN 13 : 0128054026
Total Pages : 476 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Immunity and Inflammation in Health and Disease by : Shampa Chatterjee

Download or read book Immunity and Inflammation in Health and Disease written by Shampa Chatterjee and published by Academic Press. This book was released on 2017-08-31 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption