The Identities Of Membrane Steroid Receptors

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The Identities of Membrane Steroid Receptors

Author : Cheryl S. Watson
Publisher : Springer Science & Business Media
ISBN 13 : 1461503396
Total Pages : 220 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Identities of Membrane Steroid Receptors by : Cheryl S. Watson

Download or read book The Identities of Membrane Steroid Receptors written by Cheryl S. Watson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question "how do steroids mediate rapid nongenomic effects?" Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells.

The Identities of Membrane Steroid Receptors

Author : Cheryl S Watson
Publisher :
ISBN 13 : 9781461503408
Total Pages : 224 pages
Book Rating : 4.5/5 (34 download)

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Book Synopsis The Identities of Membrane Steroid Receptors by : Cheryl S Watson

Download or read book The Identities of Membrane Steroid Receptors written by Cheryl S Watson and published by . This book was released on 2003-02-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid Receptors in Health and Disease

Author : Virinder Moudgil
Publisher : Springer Science & Business Media
ISBN 13 : 1468455419
Total Pages : 329 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Steroid Receptors in Health and Disease by : Virinder Moudgil

Download or read book Steroid Receptors in Health and Disease written by Virinder Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.

Diagnosis and Management of Ovarian Disorders

Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 568 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine

Principles of Endocrinology and Hormone Action

Author : Antonino Belfiore
Publisher : Springer
ISBN 13 : 9783319446745
Total Pages : 0 pages
Book Rating : 4.4/5 (467 download)

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Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore

Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Neurobiology of Steroids

Author : E. R. de Kloet
Publisher :
ISBN 13 : 9780121852924
Total Pages : 0 pages
Book Rating : 4.8/5 (529 download)

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Book Synopsis Neurobiology of Steroids by : E. R. de Kloet

Download or read book Neurobiology of Steroids written by E. R. de Kloet and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions. Key Features Comprehensive protocols included for the study of * Steroid kinetics and metabolism * Steroid receptors * Molecular and cellular effects of steroids * Steroid effects on integrated systems

Immunohistochemistry in Tumor Diagnostics

Author : Muin S.A. Tuffaha
Publisher : Springer Nature
ISBN 13 : 3031450248
Total Pages : 373 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Immunohistochemistry in Tumor Diagnostics by : Muin S.A. Tuffaha

Download or read book Immunohistochemistry in Tumor Diagnostics written by Muin S.A. Tuffaha and published by Springer Nature. This book was released on 2024-01-17 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new and updated edition provides an extensive overview of the antibodies employed in diagnostic tumor histopathology, and it presents concise summaries of the immunoprofiles of most tumors. Additionally, it offers practical diagnostic algorithms and invaluable tips to facilitate the interpretation of results. The work includes the newest available antibodies and the most recent 5th edition of the WHO classification of tumors. Furthermore, a chapter on biomarkers for theranostic applications has been added to enhance the book's utility. Designed as a practical and user-friendly bench reference for diagnostic tumor histopathology, this book is recommended to histopathologists of all levels, from aspiring residents to seasoned specialists seeking a reliable and comprehensive resource for tumor diagnostics. Moreover, it is highly recommended for oncologists, hematologists, and researchers involved in these fields.

The Toxicology of Fishes

Author : Richard T. Di Giulio
Publisher : CRC Press
ISBN 13 : 9780203647295
Total Pages : 1096 pages
Book Rating : 4.6/5 (472 download)

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Book Synopsis The Toxicology of Fishes by : Richard T. Di Giulio

Download or read book The Toxicology of Fishes written by Richard T. Di Giulio and published by CRC Press. This book was released on 2008-02-25 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on these organisms has been widely available, until now. Filling this void, The Toxicology of Fishes, written by recognized experts, covers toxic responses ranging from reduced reproduction and/or abnormal development, growth, and differentiation. General Principles — Discusses fundamental topics such as the bioavailability of chemicals present in the aquatic environment to fishes, processes governing chemical distribution within these organisms, how fish metabolize organic chemicals, and fundamental mechanisms of chemical toxicity Key Target Systems and Organismal Effects — Describes key target organ systems for chemical impacts in fish, how chemicals produce cancer in these animals, and how fishes can develop resistance to chemical toxicity Methodologies and Applications — Dovers methods for the assessment of chemical effects on fish such as toxicity tests, biomarkers, simulated ecosystems, and modeling approaches and the use of data from such studies in ecological risk assessments Case Studies — Provides examples of how the principles and approaches presented in earlier units are actually deployed in studies Illustrated by case studies of actual, large-scale field investigations, the book reviews the tools used to assess unwanted effects in laboratory model- and wild fish in detail. With 238 illustrations, 70 tables, and 50 equations, this comprehensive monograph presents detailed information on the boiavailability of chemical pollutants, their distribution, metabolism, and excretion in the host fish and mechanisms and sites of toxic responses.

The Life Cycle of the Corpus Luteum

Author : Rina Meidan
Publisher : Springer
ISBN 13 : 3319432389
Total Pages : 283 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Life Cycle of the Corpus Luteum by : Rina Meidan

Download or read book The Life Cycle of the Corpus Luteum written by Rina Meidan and published by Springer. This book was released on 2016-11-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the life cycle of a unique endocrine gland that is absolutely essential for the establishment and maintenance of pregnancy in all mammalian species. The corpus luteum is unique because it is formed and destroyed every (non-fertile) reproductive cycle. When fertilization occurs, the corpus luteum is rescued or maintained. The processes that control corpus luteum formation, demise (luteolysis), or maintenance are just beginning to be unraveled in recent years; they involve diverse cell types and mechanisms. Some of these processes resemble tumor development—angiogenesis, for instance—but interestingly enough, this resemblance is only up to a point. The corpus luteum uses mechanisms that allow its normal, physiological growth and disappearance. Pulling together key research on the corpus luteum, this volume is of interest to both reproductive endocrinologists and comparative physiologists, with clinical relevance spanning comparative animal studies to women's health.

The Fish Oocyte

Author : Patrick J. Babin
Publisher : Springer Science & Business Media
ISBN 13 : 1402062338
Total Pages : 513 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Fish Oocyte by : Patrick J. Babin

Download or read book The Fish Oocyte written by Patrick J. Babin and published by Springer Science & Business Media. This book was released on 2007-08-20 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the growing needs in deciphering the biological processes associated with fish reproduction, in view of the growth of aquaculture and the dwindling natural stocks of commercially important fish. It presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. With this view in mind, the book includes chapters on oocyte development (oogenesis), hormonal regulation and hormone receptors, formation of the egg envelopes, growth, accumulation of nutrients and maternal transcripts, maturation, hydration, ovulation and fertilization. A special emphasis is placed on using state-of-the-art tools including electron microscopy for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction. Studies on promoting oocyte maturation, ovulation and spawning in farmed fish and preservation of fish oocytes at low temperatures are also included. The book will appeal to University lecturers, students, research scientists and those associated with culture of fish in freshwater or marine aquaculture.

Neuromorphic Olfaction

Author : Krishna C. Persaud
Publisher : CRC Press
ISBN 13 : 1439871728
Total Pages : 237 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Neuromorphic Olfaction by : Krishna C. Persaud

Download or read book Neuromorphic Olfaction written by Krishna C. Persaud and published by CRC Press. This book was released on 2016-04-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Hormonal Carcinogenesis V

Author : Jonathan J. Li
Publisher : Springer Science & Business Media
ISBN 13 : 0387690808
Total Pages : 658 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Hormonal Carcinogenesis V by : Jonathan J. Li

Download or read book Hormonal Carcinogenesis V written by Jonathan J. Li and published by Springer Science & Business Media. This book was released on 2008-04-24 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information gathered from cell-free systems, cell cultures, animal models, and human studies, together provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. A special emphasis is placed on the two major endocrine-related cancers, that is, breast and prostate. The emerging fields of colon, lung, and pancreatic cancers in relation to hormones are examined.

Ecdysone: Structures and Functions

Author : Guy Smagghe
Publisher : Springer Science & Business Media
ISBN 13 : 1402091125
Total Pages : 583 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ecdysone: Structures and Functions by : Guy Smagghe

Download or read book Ecdysone: Structures and Functions written by Guy Smagghe and published by Springer Science & Business Media. This book was released on 2009-03-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecdysone is the steroidal prohormone of the major insect moulting hormone 20-hydroxyecdysone. It groups with its homologues the steroidal molting hormones in arthropods, but they also occur in other phyla where they can play different roles. Besides ecdysteroids appear in many plants mostly as protection agents (toxins or antifeedants) against herbivorous insects. The important developments and achievements in modern ecdysone science since the first edition in 1989 by J. Koolman have led to this new revised, expanded and retitled reference work. New chapters in this edition include RNA interference, the ecdysone receptor crystal structures and structure activity relationships, etc. Each article may also be read independently, as a review of that particular subject. Complete up-to-date coverage of many important topics - the book is divisible into five conceptual areas: (1) Distribution and diversity of ecdysteroids in the two kingdoms is still basis, (2) In the post-genomic era, ecdysteroid genetic hierarchies in insect growth and reproduction, (3) Role of cross talk of genes and growth factors in ecdysteroid titers and signaling, (4) Ecdysteroids function through nuclear and membrane receptors, and (5) Ecdysteroids in modern agriculture, medicine, doping and ecotoxicology. Each of the 23 chapters is written by scientists active in the reviewed research area and a truly distinguished international team of contributors has been chosen. Ecdysone, Structures and Functions will be of immense use and contains essential information for scientists, students, and professionals alike in entomology, endocrinology, physiology, chemistry, and agricultural, plant, biomedicine and environmental sciences.

Advances in Rapid Sex-Steroid Action

Author : Gabriella Castoria
Publisher : Springer Science & Business Media
ISBN 13 : 1461417635
Total Pages : 271 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Advances in Rapid Sex-Steroid Action by : Gabriella Castoria

Download or read book Advances in Rapid Sex-Steroid Action written by Gabriella Castoria and published by Springer Science & Business Media. This book was released on 2011-12-14 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.

The Enzymes

Author : Fuyuhiko Tamanoi
Publisher : Academic Press
ISBN 13 : 9780080460420
Total Pages : 592 pages
Book Rating : 4.4/5 (64 download)

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Book Synopsis The Enzymes by : Fuyuhiko Tamanoi

Download or read book The Enzymes written by Fuyuhiko Tamanoi and published by Academic Press. This book was released on 2011-09-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein methylation has recently emerged as one of the most exciting areas of study on posttranslational modification. A large family of protein methyltransferases has been identified and their structural properties have been characterized. These studies have provided novel insights into how methylation regulates a variety of biological functions including DNA and RNA metabolism, protein synthesis and signal transduction. Methylation also plays important roles in aging. This volume is intended to capture these recent developments concerning protein methyltransferases.

Textbook of Receptor Pharmacology

Author : John C. Foreman
Publisher : CRC Press
ISBN 13 : 1420052551
Total Pages : 314 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Textbook of Receptor Pharmacology by : John C. Foreman

Download or read book Textbook of Receptor Pharmacology written by John C. Foreman and published by CRC Press. This book was released on 2010-09-10 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from this course, the perennially bestselling Textbook of Receptor Pharmacology has presented in-depth coverage of this rapidly expanding area of research. This third edition continues to combine current understanding of classica

Endocrinology of the Testis and Male Reproduction

Author : Manuela Simoni
Publisher : Springer
ISBN 13 : 9783319444406
Total Pages : 1364 pages
Book Rating : 4.4/5 (444 download)

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Book Synopsis Endocrinology of the Testis and Male Reproduction by : Manuela Simoni

Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.