Animal Models for the Study of Human Disease

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Publisher : Academic Press
ISBN 13 : 0124159125
Total Pages : 1108 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Animal Models for the Study of Human Disease by : P. Michael Conn

Download or read book Animal Models for the Study of Human Disease written by P. Michael Conn and published by Academic Press. This book was released on 2013-05-29 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Precision Medicine and the Reinvention of Human Disease

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Publisher : Academic Press
ISBN 13 : 0128143940
Total Pages : 398 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Precision Medicine and the Reinvention of Human Disease by : Jules J. Berman

Download or read book Precision Medicine and the Reinvention of Human Disease written by Jules J. Berman and published by Academic Press. This book was released on 2018-01-26 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine. Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine. Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter. Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way. Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field.

Viruses and Human Disease

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Publisher : Elsevier
ISBN 13 : 9780080553160
Total Pages : 480 pages
Book Rating : 4.5/5 (531 download)

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Book Synopsis Viruses and Human Disease by : Ellen G. Strauss

Download or read book Viruses and Human Disease written by Ellen G. Strauss and published by Elsevier. This book was released on 2007-09-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Introduction to Human Disease (book)

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Publisher : Jones & Bartlett Publishers
ISBN 13 : 128405540X
Total Pages : 544 pages
Book Rating : 4.2/5 (84 download)

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Book Synopsis Introduction to Human Disease (book) by : Agnes G. Loeffler

Download or read book Introduction to Human Disease (book) written by Agnes G. Loeffler and published by Jones & Bartlett Publishers. This book was released on 2014-01-06 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Human Disease: Pathophysiology for Health Professionals, Sixth Edition provides a broad overview of the most common and important human diseases for students pursuing careers in the health professions. Comprehensive yet accessible, it addresses the aspects of disease epidemiology, diagnosis, and treatment that are essential to clinical practice. The Sixth Edition of this popular text has been thoroughly updated to cover the latest advances in medical knowledge and practice, especially with regard to mental health and nutritional disorders. It also includes additional clinical information on treatments for diseases. Designed to facilitate learning, this essential reference features new full-color photos and illustrations, learning objectives, and practice questions for review and assessment. Introduction to Human Disease: Pathophysiology for Health Professions, Sixth Edition will help students gain a solid foundation in disease pathology and medical terminology to help them throughout their medical education. KEY FEATURES - Provides a comprehensive introduction to the essential aspects of human disease - Covers the most common and important human diseases, including mental illnesses - Facilitates learning with chapter objectives, key terms, and practice questions - Includes more than 400 full-color illustrations, photos, and tables NEW TO THE SIXTH EDITION - New photos and illustrations - New and updated resources for instructors and students - Updated content reflects the current state of medical knowledge and practice - More clinical information, including general and specific treatments for diseases with an emphasize on common laboratory tests - Chapter 26: Infectious Diseases and Chapter 27: Immunologic Diseases are revised and now included in Section 4: Multiple Organ System Diseases - Chapters 24: Mental Illness and 30: Nutritional Disorders are revised, to bring them up-to-date with current health problems (e.g. obesity), concepts, and terminologies

Epigenetics in Human Disease

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Publisher : Academic Press
ISBN 13 : 0123884152
Total Pages : 618 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Epigenetics in Human Disease by : Trygve O. Tollefsbol

Download or read book Epigenetics in Human Disease written by Trygve O. Tollefsbol and published by Academic Press. This book was released on 2012-07-26 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Essentials of Human Disease

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Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449643892
Total Pages : 573 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Essentials of Human Disease by : Leonard V. Crowley

Download or read book Essentials of Human Disease written by Leonard V. Crowley and published by Jones & Bartlett Publishers. This book was released on 2014 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protozoa and Human Disease

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Publisher : Garland Science
ISBN 13 : 1136738169
Total Pages : 255 pages
Book Rating : 4.1/5 (367 download)

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Book Synopsis Protozoa and Human Disease by : Mark F Wiser

Download or read book Protozoa and Human Disease written by Mark F Wiser and published by Garland Science. This book was released on 2010-11-18 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protozoa and Human Disease is a textbook on medically important protozoa and the diseases they cause for advanced undergraduate students, graduate students, and professionals. It combines a taxonomic and medical approach and is therefore suitable for a parasitology, microbiology, medical, and public health readership. In addition to the basics such as morphological features, life cycles, and the clinical manifestations of the diseases, topics like the molecular and immunological basis of pathogenesis, metabolic pathways, specialized subcellular structures, ecology of disease transmission, antigenic variation, and molecular epidemiology are discussed for many of the protozoan pathogens. At the end of the book is an extensive glos

The Origins of Human Disease

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Publisher : Wiley-Blackwell
ISBN 13 : 9780631179382
Total Pages : 240 pages
Book Rating : 4.1/5 (793 download)

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Book Synopsis The Origins of Human Disease by : Thomas McKeown

Download or read book The Origins of Human Disease written by Thomas McKeown and published by Wiley-Blackwell. This book was released on 1991-08-26 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a history of the diseases of humankind and their causes from earliest times to the present day. It is a tour de force drawing upon the author's extensive work on the history of infection, as well upon evidence drawn from archaeology, history and demography.

DNA Methylation and Complex Human Disease

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Publisher : Academic Press
ISBN 13 : 0127999205
Total Pages : 552 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis DNA Methylation and Complex Human Disease by : Michel Neidhart

Download or read book DNA Methylation and Complex Human Disease written by Michel Neidhart and published by Academic Press. This book was released on 2015-08-11 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field Describes wholly new concepts, including the linking of metabolic pathways with epigenetics Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases

Human Disease and Health Promotion

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Publisher : John Wiley & Sons
ISBN 13 : 0470589086
Total Pages : 480 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Human Disease and Health Promotion by : Leslie Beale

Download or read book Human Disease and Health Promotion written by Leslie Beale and published by John Wiley & Sons. This book was released on 2017-04-10 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential tools and methodologies for real-world patient education Human Disease and Health Promotion offers a comprehensive introduction to health advocacy and patient education in a real-world context. Covering the epidemiology and pathology of major communicable and non-communicable diseases, this book details up-to-date health promotion strategies and communication approaches designed to engage diverse populations. These methodologies can inform health promotion efforts. You'll learn how to partner with the patient to navigate healthcare systems and services and how to manage the relationship to avoid patient dependence and advocate burn-out. An extensive guide to common diseases includes details on mechanism, treatment, epidemiology, pathology, and attendant psychosocial implications, and prevention and control are emphasized to the degree that the patient has the capacity to obtain, process, and understand the information and services needed to make appropriate health decisions. Rich in examples, tools, and exercises, this text includes access to a downloadable workbook that provides additional exercises to reinforce concepts and build essential practical skills. Public health education and advocacy is an enormous undertaking with many variables. This book helps provides a real-world picture of the depth and breadth of the field, with clear guidance toward current theory and practice. Apply current health literacy theories and participatory patient education strategies Design, implement, and evaluate programs targeting various groups Analyze and apply new technologies in patient education and health advocacy Understand the mechanisms, treatments, and epidemiology of common diseases Nine out of ten adults may lack the skills needed to manage their health and prevent disease, and over half find it a challenge to self-manage chronic diseases and use health services appropriately. Human Disease and Health Promotion helps you develop your role as health educator and advocate so you can connect patients with the care and information they need.

Essential Human Disease for Dentists

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Publisher : Elsevier Health Sciences
ISBN 13 : 0443100985
Total Pages : 322 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Essential Human Disease for Dentists by : Chris Sproat

Download or read book Essential Human Disease for Dentists written by Chris Sproat and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering general medicine and the implications of medical conditions for dental practice, this is a pocketbook for dental students and general dental practitioners.

Genetic Variation and Human Disease

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Publisher : Cambridge University Press
ISBN 13 : 9780521336604
Total Pages : 384 pages
Book Rating : 4.3/5 (366 download)

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Book Synopsis Genetic Variation and Human Disease by : Kenneth M. Weiss

Download or read book Genetic Variation and Human Disease written by Kenneth M. Weiss and published by Cambridge University Press. This book was released on 1993 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.

Crowley's An Introduction to Human Disease

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Publisher : Jones & Bartlett Publishers
ISBN 13 : 1284050238
Total Pages : 849 pages
Book Rating : 4.2/5 (84 download)

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Book Synopsis Crowley's An Introduction to Human Disease by : Reisner

Download or read book Crowley's An Introduction to Human Disease written by Reisner and published by Jones & Bartlett Publishers. This book was released on 2016-08-02 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by An introduction to human disease / Leonard V. Crowley. 9th ed. c2013.

The Human Microbiota and Chronic Disease

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Publisher : John Wiley & Sons
ISBN 13 : 1118982878
Total Pages : 564 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis The Human Microbiota and Chronic Disease by : Luigi Nibali

Download or read book The Human Microbiota and Chronic Disease written by Luigi Nibali and published by John Wiley & Sons. This book was released on 2016-10-03 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

Polyphenols in Human Health and Disease

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Publisher : Academic Press
ISBN 13 : 0128130091
Total Pages : 484 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polyphenols in Human Health and Disease by : Ronald Ross Watson

Download or read book Polyphenols in Human Health and Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2018-08-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Molecular Pathology

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Publisher : Academic Press
ISBN 13 : 0128027878
Total Pages : 802 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular Pathology by : William B. Coleman

Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

The Story of the Human Body

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Publisher : Vintage
ISBN 13 : 030774180X
Total Pages : 482 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis The Story of the Human Body by : Daniel Lieberman

Download or read book The Story of the Human Body written by Daniel Lieberman and published by Vintage. This book was released on 2014-07-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: A landmark book of popular science that gives us a lucid and engaging account of how the human body evolved over millions of years—with charts and line drawings throughout. “Fascinating.... A readable introduction to the whole field and great on the making of our physicality.”—Nature In this book, Daniel E. Lieberman illuminates the major transformations that contributed to key adaptations to the body: the rise of bipedalism; the shift to a non-fruit-based diet; the advent of hunting and gathering; and how cultural changes like the Agricultural and Industrial Revolutions have impacted us physically. He shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning a paradox: greater longevity but increased chronic disease. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes even compel us to create a more salubrious environment and pursue better lifestyles.