The Hla System In Clinical Transplantation

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The HLA System in Clinical Transplantation

Author : Bjarte G. Solheim
Publisher : Springer Science & Business Media
ISBN 13 : 3642775063
Total Pages : 431 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The HLA System in Clinical Transplantation by : Bjarte G. Solheim

Download or read book The HLA System in Clinical Transplantation written by Bjarte G. Solheim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: With this book we· want to address young graduate students, clini cians involved in transplantation, and technicians in transplantation immunology laboratories. The volume should give a comprehensive but basic, up to date introduction to the structure, function, and clinical importance of the HLA system. We believe that there is a need for such a survey, and think that the present level of our knowledge is an optimal occasion for publication. A significant number of ques tions have now been resolved, and our knowledge has reached a level of sophistication that provides the basis for additional questions and answers. Although the emphasis of this book is on the role of HLA anti gens in clinical transplantation, their involvement in other clinical contexts is also discussed. The main focus is on the human MHC an tigenic system, but MHC systems in other species are described as they contribute to our understanding of the structural and functional characteristics of HLA antigens. Some important issues related to laboratory techniques are also covered. The contributors have a close affiliation to the field of transplan tation immunology. A majority have even been playing important roles in unraveling the HLA system and its functions. We believe this has contributed significantly to the quality and clinical and practical relevance of the book. As editors, we drew up the principal guidelines and took care that the chapters can be read as separate entities, although this invariably results in some overlapping.

The HLA System in Clinical Transplantation

Author : Bjarte Gees Solheim
Publisher : Springer
ISBN 13 : 9783540554561
Total Pages : 429 pages
Book Rating : 4.5/5 (545 download)

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Book Synopsis The HLA System in Clinical Transplantation by : Bjarte Gees Solheim

Download or read book The HLA System in Clinical Transplantation written by Bjarte Gees Solheim and published by Springer. This book was released on 1992-12-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: With this book we· want to address young graduate students, clini cians involved in transplantation, and technicians in transplantation immunology laboratories. The volume should give a comprehensive but basic, up to date introduction to the structure, function, and clinical importance of the HLA system. We believe that there is a need for such a survey, and think that the present level of our knowledge is an optimal occasion for publication. A significant number of ques tions have now been resolved, and our knowledge has reached a level of sophistication that provides the basis for additional questions and answers. Although the emphasis of this book is on the role of HLA anti gens in clinical transplantation, their involvement in other clinical contexts is also discussed. The main focus is on the human MHC an tigenic system, but MHC systems in other species are described as they contribute to our understanding of the structural and functional characteristics of HLA antigens. Some important issues related to laboratory techniques are also covered. The contributors have a close affiliation to the field of transplan tation immunology. A majority have even been playing important roles in unraveling the HLA system and its functions. We believe this has contributed significantly to the quality and clinical and practical relevance of the book. As editors, we drew up the principal guidelines and took care that the chapters can be read as separate entities, although this invariably results in some overlapping.

The HLA Complex in Biology and Medicine

Author : Narinder K Mehra
Publisher : Boydell & Brewer Ltd
ISBN 13 : 9788184488708
Total Pages : 616 pages
Book Rating : 4.4/5 (887 download)

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Book Synopsis The HLA Complex in Biology and Medicine by : Narinder K Mehra

Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.

The HLA System

Author : John Lee
Publisher : Springer Science & Business Media
ISBN 13 : 1461234549
Total Pages : 337 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The HLA System by : John Lee

Download or read book The HLA System written by John Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.

Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition

Author : Michael Laposata
Publisher : McGraw Hill Professional
ISBN 13 : 1260116808
Total Pages : 592 pages
Book Rating : 4.2/5 (61 download)

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Book Synopsis Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition by : Michael Laposata

Download or read book Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition written by Michael Laposata and published by McGraw Hill Professional. This book was released on 2019-01-04 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acclaimed full-color guide to selecting the correct laboratory test and interpreting the results –- covering ALL of clinical pathology A Doody’s Core Title for 2019! Laboratory Medicine is the most comprehensive, user-friendly, and well-illustrated guide available for learning how to order the correct laboratory test and understand the clinical significance of the results. The book features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. With new, increasingly expensive and complicated tests appearing almost daily, Laboratory Medicine, Third Edition is required reading for medical students, clinical laboratory scientists, and healthcare professionals who want to keep abreast of the latest testing procedures and maximize accuracy and patient safety. Features: •48 clinical laboratory methods presented in easy-to-understand illustrations that include information on the expense and complexity of the assays •More than 200 tables and full-color algorithms that encapsulate important information and facilitate understanding •Full-color blood-smear micrographs that demonstrate common abnormal morphologies of red blood cells •Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction -- and new to this edition: chapter-ending self-assessment Q&A •Logical systems-based organization that complements most textbooks •Extensive table of Clinical Laboratory Reference Values that show the conversions between U.S. and SI units for each value

HLA and Disease Associations

Author : J.L. Tiwari
Publisher : Springer
ISBN 13 : 9781461385479
Total Pages : 0 pages
Book Rating : 4.3/5 (854 download)

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Book Synopsis HLA and Disease Associations by : J.L. Tiwari

Download or read book HLA and Disease Associations written by J.L. Tiwari and published by Springer. This book was released on 2011-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.

Transplantation Immunology

Author : Philip Hornick
Publisher : Springer Science & Business Media
ISBN 13 : 1597450499
Total Pages : 430 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Transplantation Immunology by : Philip Hornick

Download or read book Transplantation Immunology written by Philip Hornick and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

HLA and Disease Associations

Author : Jawahar L. Tiwari
Publisher :
ISBN 13 : 9783540960812
Total Pages : 472 pages
Book Rating : 4.9/5 (68 download)

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Book Synopsis HLA and Disease Associations by : Jawahar L. Tiwari

Download or read book HLA and Disease Associations written by Jawahar L. Tiwari and published by . This book was released on 1985 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Issues and Future Direction in Kidney Transplantation

Author : Thomas Rath
Publisher : BoD – Books on Demand
ISBN 13 : 9535109855
Total Pages : 494 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Current Issues and Future Direction in Kidney Transplantation by : Thomas Rath

Download or read book Current Issues and Future Direction in Kidney Transplantation written by Thomas Rath and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.

HLA in Health and Disease

Author : Robert Lechler
Publisher : Academic Press
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HLA in Health and Disease by : Robert Lechler

Download or read book HLA in Health and Disease written by Robert Lechler and published by Academic Press. This book was released on 2000-05-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field

The European Blood and Marrow Transplantation Textbook for Nurses

Author : Michelle Kenyon
Publisher : Springer
ISBN 13 : 3319500260
Total Pages : 311 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis The European Blood and Marrow Transplantation Textbook for Nurses by : Michelle Kenyon

Download or read book The European Blood and Marrow Transplantation Textbook for Nurses written by Michelle Kenyon and published by Springer. This book was released on 2018-03-14 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

HLA Typing

Author : Sebastian Boegel
Publisher : Humana
ISBN 13 : 9781493985456
Total Pages : 0 pages
Book Rating : 4.9/5 (854 download)

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Book Synopsis HLA Typing by : Sebastian Boegel

Download or read book HLA Typing written by Sebastian Boegel and published by Humana. This book was released on 2018-06-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the rapidly evolving field of HLA typing and its use in both the laboratory setting and in silico methods. The chapters in this book discuss high-throughput methods for HLA typing; wet lab protocols; microarray data and its uses; in silico tools for the identification of HLA alleles from DNA and RNA next-generation-sequencing data, as well as HLA haplotype frequency estimation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, HLA Typing: Methods and Protocols is a valuable resource for any researcher interested in learning more about this developing field.

The EBMT Handbook

Author : Nicolaus Kröger
Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

HLA-DR Antigens

Author : Melvin Madsen
Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.:/5 (37 download)

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Book Synopsis HLA-DR Antigens by : Melvin Madsen

Download or read book HLA-DR Antigens written by Melvin Madsen and published by . This book was released on 1983 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

The HLA System

Author : Scott Murphy
Publisher : American Association of Blood Banks (AABB)
ISBN 13 : 9781563951244
Total Pages : 184 pages
Book Rating : 4.9/5 (512 download)

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Book Synopsis The HLA System by : Scott Murphy

Download or read book The HLA System written by Scott Murphy and published by American Association of Blood Banks (AABB). This book was released on 1999 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Allogeneic Stem Cell Transplantation

Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.