The Flaviviruses Structure Replication And Evolution

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The Flaviviruses: Structure, Replication and Evolution

Author :
Publisher : Elsevier
ISBN 13 : 0080493815
Total Pages : 403 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Flaviviruses: Structure, Replication and Evolution by :

Download or read book The Flaviviruses: Structure, Replication and Evolution written by and published by Elsevier. This book was released on 2003-12-18 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase. Includes new, detailed information on the evolution, viral structure and replication of the Flavivirus family The only complete reference book on a major virus family Descibes the technologies that have contributed to our current knowledge about Flaviviruses Identifies the major problems faced in understanding the virus-host interactions that result in disease

The Flaviviruses: Detection, Diagnosis and Vaccine Development

Author :
Publisher : Elsevier
ISBN 13 : 0080493831
Total Pages : 607 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Flaviviruses: Detection, Diagnosis and Vaccine Development by :

Download or read book The Flaviviruses: Detection, Diagnosis and Vaccine Development written by and published by Elsevier. This book was released on 2003-12-18 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions Descibes the technologies that have contributed to our current knowledge about the Flaviviruses Identifies the major problems faced in understanding the virus-host interactins that result in disease An exhaustive compendium of current and past knowledge on the Flavivirus family

The Togaviridae and Flaviviridae

Author : Sondra Schlesinger
Publisher : Springer Science & Business Media
ISBN 13 : 1475707851
Total Pages : 464 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis The Togaviridae and Flaviviridae by : Sondra Schlesinger

Download or read book The Togaviridae and Flaviviridae written by Sondra Schlesinger and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this volume of The Viruses entitled The Togaviridae and Flaviviridae comes at an appropriate time. The structure and rep lication strategies of these viruses are now known to be sufficiently di verse to warrant the removal of flaviviruses from the Togaviridae family and establish them as an independent family. Flaviviridae have a special place in the history of virology. The prototype virus-yellow fever virus was the first virus to be identified as the cause of a human disease. Some of the history of this discovery is described in Chapter 1 of this volume; in Chapter 10 the complete sequence of the RNA genome of the virus is presented. This sequence not only defines the primary structure of the viral proteins, it also clarifies the mechanism of translation of the fla vivirus genome. Knowledge of the sequence of the structural proteins of these viruses represents an important step in the potential goal of using purified flavivirus glycoproteins as vaccines. Many of the chapters in this volume focus on the structure and replication of the Togaviridae. These viruses have provided valuable models for studies in cell biology, partic ularly with regard to the cotranslational and posttranslational steps re quired for the synthesis and localization of membrane glycoproteins. Fur thermore, Togaviridae have been pivotal in our growing understanding of how enveloped viruses enter and exit from cells. The broad outlines of the structure and gene expression of Togavir idae and Flaviviridae are known, but important questions remain.

Molecular Biology of the Flavivirus

Author : Matthias Kalitzky
Publisher : Taylor & Francis
ISBN 13 : 9781904933229
Total Pages : 380 pages
Book Rating : 4.9/5 (332 download)

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Book Synopsis Molecular Biology of the Flavivirus by : Matthias Kalitzky

Download or read book Molecular Biology of the Flavivirus written by Matthias Kalitzky and published by Taylor & Francis. This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flaviviruses constitute a family of linear, single-stranded RNA(+) viruses. They cause approximately 70 different diseases which have a major impact on national economies and health authorities worldwide. This book reviews the most significant cutting edge discoveries in the flavivirus field. Aspects of molecular biology common to flaviviruses are explored in depth. Topics include the evolution and function of flavivirus RNA, flavivirus replication, laboratory diagnosis and vaccine development. Individual chapters are devoted to the molecular biology of yellow fever virus, dengue virus, Japanese encephalitis virus, and hepatitis C virus. This book is essential for all flavivirus researchers and a recommended text for all virology laboratories.

Origin and Evolution of Viruses

Author : Esteban Domingo
Publisher : Elsevier
ISBN 13 : 0080564968
Total Pages : 573 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Origin and Evolution of Viruses by : Esteban Domingo

Download or read book Origin and Evolution of Viruses written by Esteban Domingo and published by Elsevier. This book was released on 2008-06-23 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

The Togaviruses

Author : Walter R Schlesinge
Publisher : Elsevier
ISBN 13 : 0323138268
Total Pages : 704 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Togaviruses by : Walter R Schlesinge

Download or read book The Togaviruses written by Walter R Schlesinge and published by Elsevier. This book was released on 2012-12-02 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Togaviruses: Biology, Structure, Replication deals with the biology, structure, and replication of rotaviruses. This book covers topics such as the biochemistry of rotaviruses and the biological and medical challenges they pose. It also gives an account of their mechanisms of replication that might lead to perceptions of the capacity to solve biological and epidemiological problems through the concepts and technology of molecular biology. This text is comprised of 21 chapters that explore clinical details, routine procedures for diagnostic virus isolation and identification and for serological tests; immunological host responses; the role of interferons; antiviral chemotherapy; and vaccine development. The discussion begins with a historical overview of arboviruses, followed by a description of all the viruses that belong to Togaviridae. These include alpha- and flaviviruses, rubiviruses, pestiviruses, and other ""non-arbo"" togaviruses. The next chapters focus on the arthropod-vertebrate-arthropod transmission cycle and its experimental equivalents, along with the viruses' structure, composition, and replication. This book concludes with a summary of physicochemical, morphological, and clinical data on non-arbo togaviruses. This reference material will be of interest to physicians, veterinarians, ecologists, entomologists, epidemiologists, cell biologists, immunologists, virologists, physical chemists, biochemists, molecular biologists, and geneticists.

Molecular Virology and Control of Flaviviruses

Author : Pei-Yong Shi
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455929
Total Pages : 0 pages
Book Rating : 4.4/5 (559 download)

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Book Synopsis Molecular Virology and Control of Flaviviruses by : Pei-Yong Shi

Download or read book Molecular Virology and Control of Flaviviruses written by Pei-Yong Shi and published by Caister Academic Press Limited. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure * virus replication * the NS1 glycoprotein * the NS3 protein * the NS5 protein * innate immunity and flavivirus infection * host responses to flavivirus infection * flavivirus fitness and transmission. The Virus Prevention section includes: vaccines * antibody therapy * small molecule antiviral development * flavivirus diagnostics * vector-virus interactions * vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.

The Togaviridae and Flaviviridae

Author : Sondra Schlesinger
Publisher :
ISBN 13 : 9781475707861
Total Pages : 472 pages
Book Rating : 4.7/5 (78 download)

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Book Synopsis The Togaviridae and Flaviviridae by : Sondra Schlesinger

Download or read book The Togaviridae and Flaviviridae written by Sondra Schlesinger and published by . This book was released on 1986-05-31 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Author : Jan Gorodkin
Publisher : Humana
ISBN 13 : 9781627037082
Total Pages : 0 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods by : Jan Gorodkin

Download or read book RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods written by Jan Gorodkin and published by Humana. This book was released on 2014-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.

Virus Bioinformatics

Author : Manja Marz
Publisher : MDPI
ISBN 13 : 3039218824
Total Pages : 330 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Virus Bioinformatics by : Manja Marz

Download or read book Virus Bioinformatics written by Manja Marz and published by MDPI. This book was released on 2020-02-21 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.

Virus as Populations

Author : Esteban Domingo
Publisher : Academic Press
ISBN 13 : 0128163321
Total Pages : 426 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Virus as Populations by : Esteban Domingo

Download or read book Virus as Populations written by Esteban Domingo and published by Academic Press. This book was released on 2019-11-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Japanese Encephalitis and West Nile Viruses

Author : John Mackenzie
Publisher : Springer Science & Business Media
ISBN 13 : 3642594034
Total Pages : 423 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Japanese Encephalitis and West Nile Viruses by : John Mackenzie

Download or read book Japanese Encephalitis and West Nile Viruses written by John Mackenzie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.

Dengue and Zika: Control and Antiviral Treatment Strategies

Author : Rolf Hilgenfeld
Publisher : Springer
ISBN 13 : 981108727X
Total Pages : 375 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Dengue and Zika: Control and Antiviral Treatment Strategies by : Rolf Hilgenfeld

Download or read book Dengue and Zika: Control and Antiviral Treatment Strategies written by Rolf Hilgenfeld and published by Springer. This book was released on 2018-05-29 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.

Human Viruses: Diseases, Treatments and Vaccines

Author : Shamim I. Ahmad
Publisher : Springer Nature
ISBN 13 : 303071165X
Total Pages : 745 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Human Viruses: Diseases, Treatments and Vaccines by : Shamim I. Ahmad

Download or read book Human Viruses: Diseases, Treatments and Vaccines written by Shamim I. Ahmad and published by Springer Nature. This book was released on 2021-05-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses current evidence on human viruses and provides an extensive coverage of newly emerged viruses and current strategies for treatment. Offering a new perspective in view of the re-emergence of Ebola in African countries and Dengue in India and Pakistan, the contents include chapters on emergence, pathogenicity, epidemiology and vaccine uptake. Human Viruses: Diseases, Treatments and Vaccines: The New Insights discusses a range of viruses from the most common such as Influenza and Hepatitis to Zika, Poliomyelitis and Chikungunya among many others. It is authored by a team of experts on viral disease and will be of immense use to virologists, public health experts and clinicians.

Studies in Viral Ecology, Volume 1

Author : Christon J. Hurst
Publisher : John Wiley & Sons
ISBN 13 : 1118025652
Total Pages : 389 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Studies in Viral Ecology, Volume 1 by : Christon J. Hurst

Download or read book Studies in Viral Ecology, Volume 1 written by Christon J. Hurst and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the ecology of viruses by examining their interactive dynamics with their hosting species (in this volume, in microbes and plants), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles, and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.

Mosquitoes, Communities, and Public Health in Texas

Author : Mustapha Debboun
Publisher : Academic Press
ISBN 13 : 0128145463
Total Pages : 420 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mosquitoes, Communities, and Public Health in Texas by : Mustapha Debboun

Download or read book Mosquitoes, Communities, and Public Health in Texas written by Mustapha Debboun and published by Academic Press. This book was released on 2019-09-14 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mosquitoes, Communities, and Public Health in Texas focuses on 87 known species of mosquitoes found throughout Texas. It includes information on the ecology, medical and public health importance, and biological diversity of each species. In addition, it provides detailed identification keys for both larval and adult stages of all mosquito genera and species known to occur in Texas, along a review of surveillance and control strategies. The expansion of invasive mosquitoes from other regions (including Mexico), together with climate change occurrences increase the likelihood for an increase in diseases, such as West Nile Virus, Yellow Fever, Dengue, Chikungunya and Zika. This unique work is the first unified reference and resource rich in mosquito information for medical entomologists, mosquito and vector control professionals, pest management professionals, biologists, environmentalists, wildlife professionals, government regulators, instructors of medical entomology and public health professionals who have disease or vector responsibilities, mosquito taxonomists, epidemiologists, entomology students, academia, pest control industry, and libraries, etc., with utility for medical, veterinary and health professionals. Brings into one volume the previously fragmented or unavailable information on the species of mosquitoes found in Texas and neighboring states of Mexico Provides a variety of audiences with key data on mosquito biology, distribution and how to identify each Includes a geographic distribution map, habitat associations, and medical importance on Zika, West Nile virus, Dengue and Chikungunya for each species

Molecular Virology

Author : Susanne Modrow
Publisher : Springer
ISBN 13 : 9783642207174
Total Pages : 0 pages
Book Rating : 4.2/5 (71 download)

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Book Synopsis Molecular Virology by : Susanne Modrow

Download or read book Molecular Virology written by Susanne Modrow and published by Springer. This book was released on 2013-09-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.