The Evolutionary Genetics Of Recombination And Segregation In Drosophila

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The Evolutionary Genetics of Recombination and Segregation in Drosophila

Author : Cara L.. Brand
Publisher :
ISBN 13 :
Total Pages : 123 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis The Evolutionary Genetics of Recombination and Segregation in Drosophila by : Cara L.. Brand

Download or read book The Evolutionary Genetics of Recombination and Segregation in Drosophila written by Cara L.. Brand and published by . This book was released on 2018 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: "During meiosis, sexually reproducing eukaryotes exchange genetic material via recombination and segregate homologous chromosomes into gametes. Surprisingly, some genes involved in meiotic recombination and chromosomal segregation experience frequent evolutionary turnover. Growing evidence suggests selfish genetic elements? DNA entities that promote their own transmission at the expense of other genes in the genome? are a significant evolutionary force driving rapid molecular evolution at genes involved in an otherwise conserved biological process. The research in this dissertation integrates classical, molecular, and population genetics to study the evolution of recombination rates and biased chromosomal segregation in Drosophila. First, in Chapters 2-4, I focus on the evolution of recombination rates in Drosophila. In Chapter 2, I perform an evolutionary screen to identify a meiosis gene with a history of recurrent positive selection that might contribute to differences in the rate of crossing over between two closely related Drosophila species. I then use a transgenic approach to show this gene, mei-217/mei-218, mediates the species differences in the rate and patterning of crossing over. In Chapter 3, I use further transgenic analyses to functionally dissect mei-217/mei-218 to determine which gene regions control the species differences in crossing over. In Chapter 4, I explore the long-term molecular evolution of mei-217/mei-218 and find evidence for frequent positive selection during the phylogenetic history of Drosophila. I find that mei-217/mei-218 wildtype alleles of two additional Drosophila species have also functionally diverged in their control of crossing over. I speculate that recurrent bouts of adaptive functional evolution at mei-217/-218 might reflect a history of coevolution with selfish genetic elements. Next, in Chapter 5, I turn to the evolution of a meiotic drive system, Segregation Distorter, that causes biased segregation in Drosophila melanogaster. I use molecular and population genetic tools to investigate the age, geographic origins, and population dynamics of Segregation Distorter chromosomes. I find that despite its stable frequency, Segregation Distorter chromosomes experience frequent selective sweeps and replacement events."--Pages xi-xii.

Ecological and Evolutionary Genetics of Drosophila

Author : J.S.F. Barker
Publisher : Springer Science & Business Media
ISBN 13 : 146848768X
Total Pages : 528 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Ecological and Evolutionary Genetics of Drosophila by : J.S.F. Barker

Download or read book Ecological and Evolutionary Genetics of Drosophila written by J.S.F. Barker and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecological and evolutionary genetics span many disciplines and virtually all levels of biological investigation, from the genetic information itself to the principles governing the complex organization of living things. The ideas and informa tion generated by ecological and evolutionary genetics provide the substance for strong inferences on the origins, changes and patterns of structural and functional organization in bio logical communi ties. It is the coordination of these ideas and thoughts that will provide the answers to many fundamental questions in biology. There is no doubt that Drosophilids provide strong model systems amenable to experimental manipulation and useful for testing pertinent hypotheses in ecological and evolutionary genetics. The chapters in this volume represent efforts to use Drosophila species for such a purpose. The volume consists of a dedication to William B. Heed, followed by four major sections: Ecological Genetics, Habitat Selection, Biochemical Genetics and Molecular Evolution. Each section is introduced by a short statement, and each chapter has an independent summary. The chapters contain the sub stance of talks given at a joint Australia-US workshop held January 5-10, 1989 at the University of New England, New South Wales, Australia. We are indebted to the Division of International Programs of the National Science Foundation (USA) and to the Science and Technology Collaboration Section of the Department of Industry, Technology and Commerce (Australia) for the provi sion of financial support under the US/Australia Science and Technology Agreement. Many people contributed to the preparation of this volume.

Molecular and Evolutionary Genetics of the Segregation Distorter System of Meiotic Drive in Drosophila Melanogaster

Author : Michael F. Palopoli
Publisher :
ISBN 13 :
Total Pages : 272 pages
Book Rating : 4.:/5 (86 download)

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Book Synopsis Molecular and Evolutionary Genetics of the Segregation Distorter System of Meiotic Drive in Drosophila Melanogaster by : Michael F. Palopoli

Download or read book Molecular and Evolutionary Genetics of the Segregation Distorter System of Meiotic Drive in Drosophila Melanogaster written by Michael F. Palopoli and published by . This book was released on 1995 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recombination Variability and Evolution

Author : A.B. Korol
Publisher : Springer Science & Business Media
ISBN 13 : 9780412494109
Total Pages : 384 pages
Book Rating : 4.4/5 (941 download)

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Book Synopsis Recombination Variability and Evolution by : A.B. Korol

Download or read book Recombination Variability and Evolution written by A.B. Korol and published by Springer Science & Business Media. This book was released on 1994-08-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in the fields of evloutionary genetics of recombination, the analysis of genetic markers and breeding applications. The authors analyse recombination through a consideration of computer models, large Drosophila populations and an empirical approach to current theories. Practically-orientated readers will be interested in the discussion of a wide spectrum of mapping methods and the new algorithms proposed for genetic mapping of quantitative loci.

Recombination and Meiosis

Author : Richard Egel
Publisher : Springer Science & Business Media
ISBN 13 : 3540689842
Total Pages : 406 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Recombination and Meiosis by : Richard Egel

Download or read book Recombination and Meiosis written by Richard Egel and published by Springer Science & Business Media. This book was released on 2008-07-25 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm – in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.

Evolutionary Genetics

Author : M. Prakash
Publisher : Discovery Publishing House
ISBN 13 : 9788183561921
Total Pages : 384 pages
Book Rating : 4.5/5 (619 download)

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Book Synopsis Evolutionary Genetics by : M. Prakash

Download or read book Evolutionary Genetics written by M. Prakash and published by Discovery Publishing House. This book was released on 2007 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dimensions of Gender Problems: Policies and Prospects is the outcome of the papers contributed by eminent scholars in the filed social science. There are 14 selected papers relating to the various issues on gender problem. Women are constantly living under pressure of the incidents like distorted personality development due to discrimination, threat of or actual occurrences of deception, rape, kidnapping, dowry tortures, murder, etc. The contributors of this volume drawn from different faculties have presented their well considered judicious views in rare style on various issues pertaining to development of society. The study is of paramount importance in understanding and formulating policy relating to various dimensions related to gender problems. It is hoped that researchers of social science, women studies, developmental studies, population studies and general readers interested in the problem would appreciate the work.

The Evolution of Sex

Author : Richard E. Michod
Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Evolution of Sex by : Richard E. Michod

Download or read book The Evolution of Sex written by Richard E. Michod and published by Sinauer Associates, Incorporated. This book was released on 1988 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essays on the genetic aspects of sex, genetic recombination, and genetics and the evolutionary process by molecular biologists, population geneticists, and ecologists.

A History of Genetics

Author : Alfred Henry Sturtevant
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A History of Genetics by : Alfred Henry Sturtevant

Download or read book A History of Genetics written by Alfred Henry Sturtevant and published by . This book was released on 1965 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics of Speciation

Author : David L. Jameson
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetics of Speciation by : David L. Jameson

Download or read book Genetics of Speciation written by David L. Jameson and published by . This book was released on 1977 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature of populations, races, subspecies, and species. Genetic basis of isolation. Origin of isolation - theoretical. Origin of isolation - experimental. The nature of the speciation process.

Statistical Population Genomics

Author : Julien Y Dutheil
Publisher :
ISBN 13 : 9781013271403
Total Pages : 464 pages
Book Rating : 4.2/5 (714 download)

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Book Synopsis Statistical Population Genomics by : Julien Y Dutheil

Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The Princeton Guide to Evolution

Author : David A. Baum
Publisher : Princeton University Press
ISBN 13 : 1400848067
Total Pages : 888 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Princeton Guide to Evolution by : David A. Baum

Download or read book The Princeton Guide to Evolution written by David A. Baum and published by Princeton University Press. This book was released on 2013-11-04 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Princeton Guide to Evolution is a comprehensive, concise, and authoritative reference to the major subjects and key concepts in evolutionary biology, from genes to mass extinctions. Edited by a distinguished team of evolutionary biologists, with contributions from leading researchers, the guide contains some 100 clear, accurate, and up-to-date articles on the most important topics in seven major areas: phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society. Complete with more than 100 illustrations (including eight pages in color), glossaries of key terms, suggestions for further reading on each topic, and an index, this is an essential volume for undergraduate and graduate students, scientists in related fields, and anyone else with a serious interest in evolution. Explains key topics in some 100 concise and authoritative articles written by a team of leading evolutionary biologists Contains more than 100 illustrations, including eight pages in color Each article includes an outline, glossary, bibliography, and cross-references Covers phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society

The Cooperative Gene

Author : Mark Ridley
Publisher : Simon and Schuster
ISBN 13 : 0743201612
Total Pages : 344 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis The Cooperative Gene by : Mark Ridley

Download or read book The Cooperative Gene written by Mark Ridley and published by Simon and Schuster. This book was released on 2001 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Why isn's all life pond-scum? Why are there multimillion-celled, long-lived monsters like us, built from tens of thousands of cooperating genes? Mark Ridley presents a new explanation of how complex large life forms like ourselves came to exist, showing that the answer to the greatest mystery of evolution for modern science is not the selfish gene; it is the cooperative gene." "In this thought-provoking book, Ridley breaks down how two major biological hurdles had to be overcome in order to allow living complexity to evolve: the proliferation of genes and gene-selfishness. Because complex life has more genes than simple life, the increase in gene numbers poses a particular problem for complex beings."--BOOK JACKET.

Rice Genomics, Genetics and Breeding

Author : Takuji Sasaki
Publisher : Springer
ISBN 13 : 9811074615
Total Pages : 556 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Rice Genomics, Genetics and Breeding by : Takuji Sasaki

Download or read book Rice Genomics, Genetics and Breeding written by Takuji Sasaki and published by Springer. This book was released on 2018-02-14 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in rice genomics, genetics and breeding, with a special focus on their importance for rice biology and how they are breathing new life into traditional genetics. Rice is the main staple food for more than half of the world’s population. Accordingly, sustainable rice production is a crucial issue, particularly in Asia and Africa, where the population continues to grow at an alarming rate. The book’s respective chapters offer new and timely perspectives on the synergistic effects of genomics and genetics in novel rice breeding approaches, which can help address the urgent issue of providing enough food for a global population that is expected to reach 9 billion by 2050.

Handbook of Statistical Genetics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 9780470997628
Total Pages : 1616 pages
Book Rating : 4.9/5 (976 download)

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Book Synopsis Handbook of Statistical Genetics by : David J. Balding

Download or read book Handbook of Statistical Genetics written by David J. Balding and published by John Wiley & Sons. This book was released on 2008-06-10 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.

Stem Cells in Reproductive Medicine

Author : Carlos Simón
Publisher : Cambridge University Press
ISBN 13 : 1107034477
Total Pages : 199 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Stem Cells in Reproductive Medicine by : Carlos Simón

Download or read book Stem Cells in Reproductive Medicine written by Carlos Simón and published by Cambridge University Press. This book was released on 2013-07-04 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.

Gene Drives on the Horizon

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309437873
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Gene Drives on the Horizon by : National Academies of Sciences, Engineering, and Medicine

Download or read book Gene Drives on the Horizon written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

Heterochromatin

Author : Ram Sagar Verma
Publisher : Cambridge University Press
ISBN 13 : 9780521334808
Total Pages : 324 pages
Book Rating : 4.3/5 (348 download)

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Book Synopsis Heterochromatin by : Ram Sagar Verma

Download or read book Heterochromatin written by Ram Sagar Verma and published by Cambridge University Press. This book was released on 1988-05-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The material included in Heterochromatin is impressively comprehensive and provides timely, authoritative information that would otherwise be difficult to obtain.' BioScience