Pain Management and the Opioid Epidemic

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Author :
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

The Hypothalamus-Pituitary-Adrenal Axis

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Author :
Publisher : Elsevier
ISBN 13 : 0080559360
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Hypothalamus-Pituitary-Adrenal Axis by :

Download or read book The Hypothalamus-Pituitary-Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later

Pain Modulation

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Author :
Publisher : Elsevier Publishing Company
ISBN 13 : 9780444809841
Total Pages : 454 pages
Book Rating : 4.8/5 (98 download)

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Book Synopsis Pain Modulation by : Howard L. Fields

Download or read book Pain Modulation written by Howard L. Fields and published by Elsevier Publishing Company. This book was released on 1988-01-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.

Acute Pain Management

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Author :
Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Magnesium in the Central Nervous System

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Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Masters Abstracts International

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Author :
Publisher :
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Masters Abstracts International by :

Download or read book Masters Abstracts International written by and published by . This book was released on 1993 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Society for Neuroscience Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 998 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Society for Neuroscience Abstracts by : Society for Neuroscience. Meeting

Download or read book Society for Neuroscience Abstracts written by Society for Neuroscience. Meeting and published by . This book was released on 1992 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Essence of Analgesia and Analgesics

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1139491989
Total Pages : 551 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Essence of Analgesia and Analgesics by : Raymond S. Sinatra

Download or read book The Essence of Analgesia and Analgesics written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2010-10-14 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endorphins and Opiate Antagonists in Psychiatric Research

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468411195
Total Pages : 490 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Endorphins and Opiate Antagonists in Psychiatric Research by : Nandkumar S. Shah

Download or read book Endorphins and Opiate Antagonists in Psychiatric Research written by Nandkumar S. Shah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux.

Pain Models

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331931
Total Pages : 663 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pain Models by : Hermann O. Handwerker

Download or read book Pain Models written by Hermann O. Handwerker and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model.

Stress-induced Analgesia

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stress-induced Analgesia by : M. D. Tricklebank

Download or read book Stress-induced Analgesia written by M. D. Tricklebank and published by John Wiley & Sons. This book was released on 1984 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Practical Management of Pain

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323083404
Total Pages : 1379 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Practical Management of Pain by : Honorio MD Benzon

Download or read book Practical Management of Pain written by Honorio MD Benzon and published by Elsevier Health Sciences. This book was released on 2013-09-12 with total page 1379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Understand and apply the latest developments in pain medicine with brand-new chapters covering disability assessment, central post-stroke pain, chronic widespread pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned experts in the field. Read the full text and view all the images online at expertconsult.com. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).

Case Studies in Pain Management

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107682894
Total Pages : 547 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Case Studies in Pain Management by : Alan David Kaye

Download or read book Case Studies in Pain Management written by Alan David Kaye and published by Cambridge University Press. This book was released on 2014-10-16 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by internationally recognized pain experts, this book offers 73 clinically relevant cases, accompanied by discussion in a question-and-answer format.

Psychopharmacology Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 1144 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Psychopharmacology Abstracts by :

Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1979 with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tachykinins

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540206903
Total Pages : 596 pages
Book Rating : 4.2/5 (69 download)

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Book Synopsis Tachykinins by : Peter Holzer

Download or read book Tachykinins written by Peter Holzer and published by Springer Science & Business Media. This book was released on 2004-06-17 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.

Rang & Dale's Pharmacology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0702074462
Total Pages : 809 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Rang & Dale's Pharmacology by : James M. Ritter

Download or read book Rang & Dale's Pharmacology written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2018-11-04 with total page 809 pages. Available in PDF, EPUB and Kindle. Book excerpt: World-renowned coverage of today's pharmacology at your fingertips - Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. - Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. - Features a color-coded layout for faster navigation and cross-referencing. - Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.