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Author : William F. Loomis
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.X/5 (1 download)
Download or read book The Development of Dictyostelium Discoideum written by William F. Loomis and published by . This book was released on 1982 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development Of Dictyostelium Discoideum ...
Author : Ludwig Eichinger
Publisher : Springer Science & Business Media
ISBN 13 : 1597451444
Total Pages : 556 pages
Book Rating : 4.5/5 (974 download)
Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.
Author : William Loomis
Publisher : Elsevier
ISBN 13 : 032315980X
Total Pages : 225 pages
Book Rating : 4.3/5 (231 download)
Download or read book Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.
Author : Richard H. Kessin
Publisher : Cambridge University Press
ISBN 13 : 0521583640
Total Pages : 318 pages
Book Rating : 4.5/5 (215 download)
Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.
Author : Maria Romeralo
Publisher : Springer Science & Business Media
ISBN 13 : 3642384870
Total Pages : 259 pages
Book Rating : 4.6/5 (423 download)
Download or read book Dictyostelids written by Maria Romeralo and published by Springer Science & Business Media. This book was released on 2013-07-16 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.
Author : William Loomis
Publisher : Elsevier
ISBN 13 : 0323145663
Total Pages : 570 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.
Author : Laurence Marechal-Drouard
Publisher : Academic Press
ISBN 13 : 0123942799
Total Pages : 486 pages
Book Rating : 4.1/5 (239 download)
Download or read book Mitochondrial Genome Evolution written by Laurence Marechal-Drouard and published by Academic Press. This book was released on 2012-10-03 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on Mitochondrial genome evolution. Publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences Features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology This thematic volume features reviews on mitochondrial genome evolution
Author : George M. Briggs
Publisher :
ISBN 13 : 9781942341826
Total Pages : pages
Book Rating : 4.3/5 (418 download)
Download or read book Inanimate Life written by George M. Briggs and published by . This book was released on 2021-07-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : T.V.N. Persaud
Publisher : Springer Science & Business Media
ISBN 13 : 9401159106
Total Pages : 240 pages
Book Rating : 4.4/5 (11 download)
Download or read book Teratogenic Mechanisms written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. This book brings together some of the more recent and important research findings related to the mechanisms and pathogenesis of abnormal develop ment. It is not only a documentation of the latest experimental work, but it also points out future directions that seem productive and challenging.
Author : Kenneth Bryan Raper
Publisher : Princeton University Press
ISBN 13 : 1400856566
Total Pages : 467 pages
Book Rating : 4.4/5 (8 download)
Download or read book The Dictyostelids written by Kenneth Bryan Raper and published by Princeton University Press. This book was released on 2014-07-14 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kenneth Raper tells how dictyostelids are isolated, cultivated, and conserved in the laboratory; how myxamoebae aggregate to form multicellular pseudoplasmodia; how fructifications arise by transformation of amoeboid cells into stalk cells and spores; and how similar cells can, under certain conditions, enter a sexual phase. For each known dictyostelid Professor Raper includes a complete description and photographic illustrations; one new species is described. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Author : Robert T. Gerlai
Publisher : Academic Press
ISBN 13 : 0128041161
Total Pages : 710 pages
Book Rating : 4.1/5 (28 download)
Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts
Author :
Publisher : Academic Press
ISBN 13 : 0123813506
Total Pages : 549 pages
Book Rating : 4.1/5 (238 download)
Download or read book Microtubules: in vivo written by and published by Academic Press. This book was released on 2010-09-24 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microtubules: in vivo includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton. The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation. - Includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton - The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation
Author : Daniele D’Ambrosio
Publisher : Springer Science & Business Media
ISBN 13 : 1592594352
Total Pages : 283 pages
Book Rating : 4.5/5 (925 download)
Download or read book Cell Migration in Inflammation and Immunity written by Daniele D’Ambrosio and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angiogenesis, tissue architecture, and organogenesis. The basis for such diversified activities rests, on one hand, upon the ubiquitous nature of chemokine production and chemokine receptor expression. Virtually every cell type can produce chemokines and expresses a unique combination of chemokine receptors. On the other hand, chemokine receptors make use of a flexible and complex network of intracellular signaling machineries that can regulate a variety of cellular functions ranging from cell migration, growth, and differentiation to death. As knowledge of the size of chemokine and chemokine receptor families rapidly reaches completeness, much is still to be uncovered in terms of fu- tional architecture of the chemokine system. The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand–receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.
Author : Paul Harrison
Publisher : CRC Press
ISBN 13 : 9814411981
Total Pages : 484 pages
Book Rating : 4.8/5 (144 download)
Download or read book Extracellular Vesicles in Health and Disease written by Paul Harrison and published by CRC Press. This book was released on 2014-05-02 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on "Microvesicles and Nanovesicles in Health and Disease" held at Magdalen College, Oxford, in 2010. The purpose of the meeting was to bring together, for the first time, a range of experts from around the world to discuss the latest advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A major section of the meeting focused on a range of exciting new technologies which have been developed for this purpose. The presentations at this meeting form the basis of this book, which will appeal to basic scientists, clinicians, and those developing technology for the measurement of extracellular vesicles.
Author : Kinko Tsuji
Publisher : Springer
ISBN 13 : 3030057984
Total Pages : 297 pages
Book Rating : 4.0/5 (3 download)
Download or read book Spirals and Vortices written by Kinko Tsuji and published by Springer. This book was released on 2019-04-04 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book explores the fascinating and ubiquitous occurrence of spirals and vortices in human culture and in nature. Spiral forms have been used as elements in the arts for thousands of years, whereas their role in nature and science – from DNA and sea shells to galaxies – is still a topic of investigation in numerous fields. Following an introduction to the cultural history of spiral forms, the book presents contributions from leading experts, who describe the origins, mechanisms and dynamics of spirals and vortices in their special fields. As a whole the book provides a valuable source of information, while also taking the reader on an aesthetic and scientific journey through the world of spiral forms.
Author : Mary S. Tyler
Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.X/5 (4 download)
Download or read book Developmental Biology written by Mary S. Tyler and published by Sinauer Associates, Incorporated. This book was released on 1994 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hirobumi Suzuki
Publisher :
ISBN 13 : 9781839623868
Total Pages : 0 pages
Book Rating : 4.6/5 (238 download)
Download or read book Bioluminescence written by Hirobumi Suzuki and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains seven chapters on bioluminescence techniques and organisms. On the technical side, the four chapters presented the fluorescent markers of proteins and nanocrystals, imidazopyrazine-type luciferin that emits light when bound to human serum albumin, firefly luciferin that emits near-infrared light, and imaging technique for visualization of promoter activity in fruiting body formation of cellular slime molds Dictyostelium. On the organismal side, the three chapters presented recommendations for the commercial use of fireflies in urban areas from the perspective of conservation biology, the origin of luciferin by predation in marine luminescent organisms, and the ecology and behavior of luminescent organisms from sea to land, which will be of interest to both professionals and students.
