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The Contribution Of K Ion Channels And The Ca2 Permeable Trpm8 Channel To Breast Cancer Cell Proliferation
Download The Contribution Of K Ion Channels And The Ca2 Permeable Trpm8 Channel To Breast Cancer Cell Proliferation full books in PDF, epub, and Kindle. Read online The Contribution Of K Ion Channels And The Ca2 Permeable Trpm8 Channel To Breast Cancer Cell Proliferation ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis The Contribution of K+ Ion Channels and the Ca2+-permeable TRPM8 Channel to Breast Cancer Cell Proliferation by : Jeremy Roy
Download or read book The Contribution of K+ Ion Channels and the Ca2+-permeable TRPM8 Channel to Breast Cancer Cell Proliferation written by Jeremy Roy and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Voltage Gated Sodium Channels by : Peter C. Ruben
Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
Download or read book Ion Channels in Cancer written by and published by Elsevier. This book was released on 2023-11-15 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion Channels in Cancer, Volume 92 in the Current Topics in Membranes series, highlights advances in the field, including chapters on the Interplay of calcium and potassium signals in cell cycle and cancer, Non-conducting functions of ion channels in cancer and neurological disease, Sodium channels and progression of solid tumors, The Elusive Nav1.7: From Pain to Cancer, Signaling Pathways in cancer: Channels Interactome as a novel therapeutic target, Ion channels in cancer drugs resistance, CLIC1: A potential therapeutic target for malignant glioma, Beyond the Building Blocks: Amino Acids as modulators of ion channels and transporters, and Activation of potassium channels unveils tumor vulnerability.
Book Synopsis Autophagy and Cancer by : Hong-Gang Wang
Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it.
Book Synopsis Calcium Entry Channels in Non-Excitable Cells by : Juliusz Ashot Kozak
Download or read book Calcium Entry Channels in Non-Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Book Synopsis Tumor Microenvironment Signaling Networks in Pathophysiology and Therapeutics by : Francesca Pirini
Download or read book Tumor Microenvironment Signaling Networks in Pathophysiology and Therapeutics written by Francesca Pirini and published by Frontiers Media SA. This book was released on 2022-10-19 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tumor Vascularization by : Domenico Ribatti
Download or read book Tumor Vascularization written by Domenico Ribatti and published by Academic Press. This book was released on 2020-01-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels. Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment
Book Synopsis Transient Receptor Potential (TRP) Channels by : Veit Flockerzi
Download or read book Transient Receptor Potential (TRP) Channels written by Veit Flockerzi and published by Springer Science & Business Media. This book was released on 2007-02-07 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression.
Book Synopsis TRP Channels as Therapeutic Targets by : Arpad Szallasi
Download or read book TRP Channels as Therapeutic Targets written by Arpad Szallasi and published by Academic Press. This book was released on 2015-04-09 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them
Book Synopsis Handbook of Ion Channels by : Jie Zheng
Download or read book Handbook of Ion Channels written by Jie Zheng and published by CRC Press. This book was released on 2015-02-25 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
Author :Rosalyn D. Blumenthal Publisher :Springer Science & Business Media ISBN 13 :1592598692 Total Pages :234 pages Book Rating :4.5/5 (925 download)
Book Synopsis Chemosensitivity by : Rosalyn D. Blumenthal
Download or read book Chemosensitivity written by Rosalyn D. Blumenthal and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity, Volume 1: In Vitro Assays provides a panel of 16 in vitro measures of chemosensitivity in adherent and non-adherent cells for single agents and combinations of agents. In addition to immunohistochemical and imaging approaches, these assays include clonogenic, colorimetric, fluorometric, and physiological assays. Highlights include image analysis to assess drug sensitivity, high throughput approaches using green fluorescent protein, DIMSCAN (a microcomputer fluorescence-based assay), and the ChemoFx assay used in biotechnology. A companion volume, Volume 2: In Vivo Models, Imaging, and Molecular Regulators, provides protocols for classifying tumors into response categories and customizing chemotherapy regimens to individual patients.
Book Synopsis Nanoscale Biophysics of the Cell by : Mohammad Ashrafuzzaman
Download or read book Nanoscale Biophysics of the Cell written by Mohammad Ashrafuzzaman and published by Springer. This book was released on 2018-04-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macroscopic cellular structures and functions are generally investigated using biological and biochemical approaches. But these methods are no longer adequate when one needs to penetrate deep into the small-scale structures and understand their functions. The cell is found to hold various physical structures, molecular machines, and processes that require physical and mathematical approaches to understand and indeed manipulate them. Disorders in general cellular compartments, perturbations in single molecular structures, drug distribution therein, and target specific drug-binding, etc. are mostly physical phenomena. This book will show how biophysics has revolutionized our way of addressing the science and technology of nanoscale structures of cells, and also describes the potential for manipulating the events that occur in them.
Book Synopsis Handbook of Essential Oils by : K. Husnu Can Baser
Download or read book Handbook of Essential Oils written by K. Husnu Can Baser and published by CRC Press. This book was released on 2009-12-28 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Egyptian hieroglyphs, Chinese scrolls, and Ayurvedic literature record physicians administering aromatic oils to their patients. Today society looks to science to document health choices and the oils do not disappoint. The growing body of evidence of their efficacy for more than just scenting a room underscores the need for production standards, quality control parameters for raw materials and finished products, and well-defined Good Manufacturing Practices. Edited by two renowned experts, the Handbook of Essential Oils covers all aspects of essential oils from chemistry, pharmacology, and biological activity, to production and trade, to uses and regulation. Bringing together significant research and market profiles, this comprehensive handbook provides a much-needed compilation of information related to the development, use, and marketing of essential oils, including their chemistry and biochemistry. A select group of authoritative experts explores the historical, biological, regulatory, and microbial aspects. This reference also covers sources, production, analysis, storage, and transport of oils as well as aromatherapy, pharmacology, toxicology, and metabolism. It includes discussions of biological activity testing, results of antimicrobial and antioxidant tests, and penetration-enhancing activities useful in drug delivery. New information on essential oils may lead to an increased understanding of their multidimensional uses and better, more ecologically friendly production methods. Reflecting the immense developments in scientific knowledge available on essential oils, this book brings multidisciplinary coverage of essential oils into one all-inclusive resource.
Book Synopsis Mammalian Transient Receptor Potential (TRP) Cation Channels by : Bernd Nilius
Download or read book Mammalian Transient Receptor Potential (TRP) Cation Channels written by Bernd Nilius and published by Springer. This book was released on 2014-06-24 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
Book Synopsis Bioactive Essential Oils and Cancer by : Damião Pergentino de Sousa
Download or read book Bioactive Essential Oils and Cancer written by Damião Pergentino de Sousa and published by Springer. This book was released on 2015-09-10 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a general overview of the therapeutic potential of the essential oils in cancer and highlights some promising future directions. It integrates chemistry, pharmacology, and medicine while discussing bioactive essential oils in experimental models and clinical studies of cancer. The book is a valuable resource for all engaged in the study of natural products and their synthetic derivatives, particularly for those interested in academic research and pharmaceutical and food industries dedicated in the discovery of useful agents for the therapy or prevention of cancer.
Book Synopsis Fascinating Facts About Phytonutrients in Spices and Healthy Food by : Louis S. Premkumar
Download or read book Fascinating Facts About Phytonutrients in Spices and Healthy Food written by Louis S. Premkumar and published by Xlibris Corporation. This book was released on 2014-03-25 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, there have been claims that healthy food garnished with exotic spices and condiments provides vital nutrients that help ward off diseases, especially preventable diseases such as diabetes and heart disease (hypertension, coronary artery disease) and promote longevity. The purpose of writing this book is to update the public about the health benefits of ingredients (phytochemicals) in spices and healthy food using existing scientific evidence. The ultimate proof of health benefits will be deciphered by the isolation and identification of specific phytochemicals acting on specific receptors in the body exerting their biological effects. The important point being emphasized is that if the physiological effect of an ingredient is glaring, it is considered to elicit a significant response. However, when the effect of an ingredient is significant, yet the effect is not readily perceivable then the usefulness goes unnoticed and can be questioned as a myth. For example, coffee has several ingredients, but only caffeine acting on the adenosine receptors stimulates the central nervous system and promotes wakefulness. Similarly, the specific active ingredient in hot chili pepper, capsaicin, activates a member of a recently identified family of receptors called transient receptor potential (TRP) channels. TRP vanilloid 1 (TRPV1), which is involved in certain modalities of pain, promotes the release of hormones in the gastrointestinal (GI) tract. Although, the bioavailability of the active ingredients is low, it is important to realize that these ingredients can cause significant local effects in the GI tract by preventing cholesterol regeneration by subduing microbiota, inhibiting precancerous growth by promoting calcium influx and stimulating nerve endings to transmit information and to release of gut hormones that are involved in regulating a variety of functions including appetite and satiety.
Book Synopsis Ion Channel Signalling in Cancer: From Molecular Mechanisms to Therapeutics by : Elena Adinolfi
Download or read book Ion Channel Signalling in Cancer: From Molecular Mechanisms to Therapeutics written by Elena Adinolfi and published by Frontiers Media SA. This book was released on 2021-08-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt:
