The Collagens Biochemistry And Pathophysiology

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The Collagens: Biochemistry and Pathophysiology

Author : Eugene J. Kucharz
Publisher : Springer Science & Business Media
ISBN 13 : 3642761976
Total Pages : 429 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Collagens: Biochemistry and Pathophysiology by : Eugene J. Kucharz

Download or read book The Collagens: Biochemistry and Pathophysiology written by Eugene J. Kucharz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.

Biochemistry of Collagen

Author : Gopalasamudram Ramachandran
Publisher : Springer Science & Business Media
ISBN 13 : 1475746024
Total Pages : 546 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biochemistry of Collagen by : Gopalasamudram Ramachandran

Download or read book Biochemistry of Collagen written by Gopalasamudram Ramachandran and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.

Connective Tissues

Author : R. Fricke
Publisher : Springer Science & Business Media
ISBN 13 : 3642619320
Total Pages : 469 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Connective Tissues by : R. Fricke

Download or read book Connective Tissues written by R. Fricke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: connective tissues are essential for the physical functioning of the animals's body. The condition of the various connective tissues is governed by biochemical factors, anabolism and catabolism, that are controlled by specific enzymes. Any change outside the normal range of metabolism, for instance induced by immunological reactions, may induce a pathological disturbance. The result can be acute or chronic inflammation, or loss of normal function, expressed in loosening, dilatation, breaking, wear, stiffness, shrinking, scars, stenosis, and cirrhosis or any other kind of fibrosis. A first step toward improving our understanding of the feedback mecha nism that maintains the biological status and texture of a given connective tissue is to combine what is known about synthesis and enzymatic degradation of the components of fibers and ground substance. Common pathological phenomena like chronic inflammation of immune reactions can be either the result of the cause of disturbances in the sensitive balance of connective tissue metabolism. Nowadays con nective tissues are less and less regarded as brady trophic tissue but rather as a stimulating and many-sided problem of research. Before we can understand the pathogenesis of the connective tissue diseases that result in the destructive processes mentioned above, basic research will be necessary. This research will be furthered by a constant exchange of information and the results of· observations. To promote this exchange of information between scientists, symposia on connective tissue research are organized at regular intervals.

Biochemistry of Collagens, Laminins and Elastin

Author : Morten Karsdal
Publisher : Academic Press
ISBN 13 : 0128098996
Total Pages : 272 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal

Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Academic Press. This book was released on 2016-07-29 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. Provides a comprehensive introduction to collagen and structural proteins Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation Includes a chapter dedicated to the biomarkers of structural proteins Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states

Structure, Molecular Biology, and Pathology of Collagen

Author : Raul Fleischmajer
Publisher :
ISBN 13 :
Total Pages : 618 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis Structure, Molecular Biology, and Pathology of Collagen by : Raul Fleischmajer

Download or read book Structure, Molecular Biology, and Pathology of Collagen written by Raul Fleischmajer and published by . This book was released on 1990 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Collagen

Author : Marcel E. Nimni
Publisher : CRC Press
ISBN 13 : 135108769X
Total Pages : 587 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Collagen by : Marcel E. Nimni

Download or read book Collagen written by Marcel E. Nimni and published by CRC Press. This book was released on 2018-01-18 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Progress in Heritable Soft Connective Tissue Diseases

Author : Jaroslava Halper
Publisher : Springer Science & Business Media
ISBN 13 : 9400778937
Total Pages : 246 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Progress in Heritable Soft Connective Tissue Diseases by : Jaroslava Halper

Download or read book Progress in Heritable Soft Connective Tissue Diseases written by Jaroslava Halper and published by Springer Science & Business Media. This book was released on 2014-01-18 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them. Progress in Heritable Soft Connective Tissue Diseases features very prominent physicians and scientists as contributors who bring their most recent discoveries to the benefit of readers. Their expertise will help clinicians with proper diagnosis of sometimes elusive and uncommon heritable diseases of soft connective tissues. This book also offers an update on the pathophysiology of these diseases, including an emphasis on unifying aspects such as connections between embryonic development of the different types of connective tissues and systems, and the role of TGF-beta in development and physiology of soft tissues. This new set of data explains, at least in part, why many of these disorders are interconnected, though the primary pathophysiological events, such as gene mutations, may be different for each disorder.

Connective Tissue Disease

Author : Jouni Uitto
Publisher : CRC Press
ISBN 13 : 1000447227
Total Pages : 576 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Connective Tissue Disease by : Jouni Uitto

Download or read book Connective Tissue Disease written by Jouni Uitto and published by CRC Press. This book was released on 2021-07-29 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.

COLLAGEN BIOCHEMISTRY

Author : Marcel E. Nimni
Publisher : Springer
ISBN 13 :
Total Pages : 318 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis COLLAGEN BIOCHEMISTRY by : Marcel E. Nimni

Download or read book COLLAGEN BIOCHEMISTRY written by Marcel E. Nimni and published by Springer. This book was released on 1988-02-29 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Collagen Biochemistry & Biomechanics

Author : Marcel E. Nimni
Publisher : Springer
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Collagen Biochemistry & Biomechanics by : Marcel E. Nimni

Download or read book Collagen Biochemistry & Biomechanics written by Marcel E. Nimni and published by Springer. This book was released on 1988-02-29 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Cell Biology of Extracellular Matrix

Author : E.D. Hay
Publisher : Springer Science & Business Media
ISBN 13 : 1461537703
Total Pages : 478 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cell Biology of Extracellular Matrix by : E.D. Hay

Download or read book Cell Biology of Extracellular Matrix written by E.D. Hay and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Connective Tissues

Author : Fritz Hartmann
Publisher :
ISBN 13 : 9780354006675
Total Pages : 309 pages
Book Rating : 4.0/5 (66 download)

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Book Synopsis Connective Tissues by : Fritz Hartmann

Download or read book Connective Tissues written by Fritz Hartmann and published by . This book was released on 1974 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Pathology of Connective Tissues

Author : Ruy Pérez-Tamayo
Publisher :
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Pathology of Connective Tissues by : Ruy Pérez-Tamayo

Download or read book Molecular Pathology of Connective Tissues written by Ruy Pérez-Tamayo and published by . This book was released on 1973 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over forty speeches by the leaders of twenty-two tribes reflect the Indian's thoughts and feelings on the advance of white settlers.

Molecular Biology of Collagen Matrix in the Heart

Author : Mahboubeh Eghbali-Webb
Publisher : Springer
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Biology of Collagen Matrix in the Heart by : Mahboubeh Eghbali-Webb

Download or read book Molecular Biology of Collagen Matrix in the Heart written by Mahboubeh Eghbali-Webb and published by Springer. This book was released on 1995-01-20 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the molecular and cellular biology of the collagen matrix of the heart. It is now recognized that the remodeling of the fibrillar collagen matrix that occurs under various pathophysiological conditions may adversely alter myocardial stiffness and ultimately lead to heart failure. This book begins with a comprehensive introductory chapter on the collagen matrix in general, including information on collagen types and their tissue specificity. The book then focuses on different aspects of the molecular and cellular biology of the collagen matrix in the heart, the impact of growth factors on the expression of the myocardial collagen matrix, and myocardial collagen gene regulation under pathophysiological conditions.

Extracellular Matrix Biochemistry

Author : Karl A. Piez
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Extracellular Matrix Biochemistry by : Karl A. Piez

Download or read book Extracellular Matrix Biochemistry written by Karl A. Piez and published by Elsevier Publishing Company. This book was released on 1984 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biochemistry of Collagen

Author : Gopalasamudram Ramachandran
Publisher :
ISBN 13 : 9781475746037
Total Pages : 558 pages
Book Rating : 4.7/5 (46 download)

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Book Synopsis Biochemistry of Collagen by : Gopalasamudram Ramachandran

Download or read book Biochemistry of Collagen written by Gopalasamudram Ramachandran and published by . This book was released on 2014-01-15 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Collagen

Author : Peter Fratzl
Publisher : Springer Science & Business Media
ISBN 13 : 0387739068
Total Pages : 516 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Collagen by : Peter Fratzl

Download or read book Collagen written by Peter Fratzl and published by Springer Science & Business Media. This book was released on 2008-05-10 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.