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The Chemistry Of Lactams
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Book Synopsis The Chemistry of β-Lactams by : M.I. Page
Download or read book The Chemistry of β-Lactams written by M.I. Page and published by Springer. This book was released on 2012-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Book Synopsis The Chemistry of β-Lactams by : M.I. Page
Download or read book The Chemistry of β-Lactams written by M.I. Page and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Book Synopsis The Organic Chemistry of B [beta]-lactams by : Gunda I. Georg
Download or read book The Organic Chemistry of B [beta]-lactams written by Gunda I. Georg and published by . This book was released on 1992 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of β-Lactam Antibiotics by : Alle Bruggink
Download or read book Synthesis of β-Lactam Antibiotics written by Alle Bruggink and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Download or read book Beta-Lactams written by Bimal K. Banik and published by Springer. This book was released on 2017-05-11 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Book Synopsis The Chemistry of [beta]-lactams by : Michael I. Page
Download or read book The Chemistry of [beta]-lactams written by Michael I. Page and published by . This book was released on 1992 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heterocyclic Scaffolds I by : Bimal K. Banik
Download or read book Heterocyclic Scaffolds I written by Bimal K. Banik and published by Springer Science & Business Media. This book was released on 2010-06-08 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams
Book Synopsis Chemistry of Penicillin by : Hans T. Clarke
Download or read book Chemistry of Penicillin written by Hans T. Clarke and published by Princeton University Press. This book was released on 2015-12-08 with total page 1116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book makes available, for interested scientists to procure, absorb, and evaluate, the vast body of information on the research and results of the work on the chemistry of penicillin done in England and the United States during the war. The National Academy of Sciences arranged for the preparation of this summary, Dr. H. T. Clarke and Dr. J. R. Johnson representing the United States on the editorial board, and Sir Robert Robinson representing Britain. The body of the work was prepared by more than 60 outstanding biochemists and biophysicists, who describe the phases of research to which they contributed the most. The work of 23 academic, medical, industrial, and government laboratories is reported. Originally published in 1949. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Book Synopsis Heterocyclic Scaffolds I by : Bimal K. Banik
Download or read book Heterocyclic Scaffolds I written by Bimal K. Banik and published by Springer. This book was released on 2010-06-01 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams
Book Synopsis β-Lactams: Unique Structures of Distinction for Novel Molecules by : Bimal K. Banik
Download or read book β-Lactams: Unique Structures of Distinction for Novel Molecules written by Bimal K. Banik and published by Springer. This book was released on 2012-09-28 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: I. Ojima • E. S. Zuniga • J. D. Seitz: Advances in the Use of Enantiopure β-Lactams for the Synthesis of Biologically Active Compounds of Medicinal Interests.- I. Fernández • Miguel A. Sierra: β -Lactams from Fischer Carbene Complexes: Scope, Limitations, and Reaction Mechanism.- Bablee Mandal • Basudeb Basu: Synthesis of β-Lactams Through Alkyne–Nitrone Cycloadditions.- T. T. Tidwell: Preparation of Bis-β-Lactams by Ketene–Imine Cycloadditions.- Edward Turos: The Chemistry and Biology of N-Thiolated β-Lactams.- Indrani Banik • Bimal K. Banik: Synthesis of β-Lactams and Their Chemical Manipulations Via Microwave-Induced Reactions.
Book Synopsis Activity-Based Protein Profiling by : Stephan A. Sieber
Download or read book Activity-Based Protein Profiling written by Stephan A. Sieber and published by Springer Science & Business Media. This book was released on 2012-02-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: ABPP Methodology: Introduction and Overview, by Matthew B. Nodwell und Stephan A. Sieber Activity-Based Protein Profiling for Natural Product Target Discovery, by Joanna Krysiak und Rolf Breinbauer Photoaffinity Labeling in Activity-Based Protein Profiling, by Paul P. Geurink, Laurette M. Prely, Gijs A. van der Marel, Rainer Bischoff und Herman S. Overkleeft Application of Activity-Based Protein Profiling to the Study of Microbial Pathogenesis, by William P. Heal und Edward W. Tate Functional Analysis of Protein Targets by Metabolomic Approaches, by Yun-Gon Kim und Alan Saghatelian
Book Synopsis Beta-lactams: Natural and Synthetic by : Maghar S. Manhas
Download or read book Beta-lactams: Natural and Synthetic written by Maghar S. Manhas and published by John Wiley & Sons. This book was released on 1971 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Isocyanide-based Multicomponent Reactions by : Jonathan G. Rudick
Download or read book Isocyanide-based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Chemistry and Biology of [beta]-lactam Antibiotics by : Robert B. Morin
Download or read book Chemistry and Biology of [beta]-lactam Antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Natural Lactones and Lactams by : Tomasz Janecki
Download or read book Natural Lactones and Lactams written by Tomasz Janecki and published by John Wiley & Sons. This book was released on 2013-09-03 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there are numerous books on heterocycles and natural products, this text fills the need for an up-to-date summary focusing on recently developed and improved synthetic methods for the preparation of the most important classes of lactones and lactams - all in one volume. Comprehensive in its coverage, this book also provides readers with a brief description of the occurrence and biological or pharmaceutical activity of the compounds, and each chapter deals with a certain class of lactones or lactames to enable quick access to the information needed. A valuable resource for organic chemists, biochemists and medicinal chemists in academia and industry wanting to learn about successful synthetic routes leading to important natural products and use this as inspiration for their own work in the lab.
Book Synopsis Recent Progress in the Chemical Synthesis of Antibiotics by : Gabor Lukacs
Download or read book Recent Progress in the Chemical Synthesis of Antibiotics written by Gabor Lukacs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class have also reached an important place in the medical treatment of human cancer. Although, the discovery of most of these agents came from more or less sophisticated screening programs of soil microrganisms, many of the important antibiotics used today in clinical practice are derived from the original biosynthetic products by the application of often novel and generally elaborated chemical synthetic methodologies. In fact the antibiotics have represented (and still represent) for a generation of organic chemists an endless source of molecular structures whose varied assemblage of carbon atom backbones and chemical functions was beyond any possibility of imagination. Perhaps a similar repertoire of chemotypes was formerly offered by the natural products, namely the alkaloids, the terpenes, the vitamins and hormones as well as the pigments of the animal and plant kingdoms, albeit the chemical arrange ments of the antibiotic molecules appeared much more surprising and diverse to the admiring eyes of cultivated organic chemists. The idea of this book, certainly a landmark in the field, came during the Symposium of EUCHEM on Chemical Synthesis of Antibiotics, that was held at Aussois in Savoy, France (May 2-6, 1988), the initiative being taken by Gabor Lukacs to whom Masaji Ohno readily associated as a co-editor.
Book Synopsis The Chemistry and Biology of Beta-Lactams by : Daniel Zerong Wang
Download or read book The Chemistry and Biology of Beta-Lactams written by Daniel Zerong Wang and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This new volume, The Chemistry and Biology of Beta-Lactams, provides the most updated information about beta-lactams relating to both the pharmaceutical industry and synthetic chemistry. It provides valuable information regarding antibiotic activities as well as chemical reactivities of beta-lactams, which are important because they are commonly applied as antibiotics in the treatment of bacterial infections. Presenting the most up-to-date literature information on beta-lactams, the volume provides comprehensive coverage of most of the known beta-lactam antibiotics with both structural and biological information, antibiotic mechanisms, self-defense mechanisms of bacteria, nearly all known synthetic methods for the preparation of beta-lactams, and possible reactions in which beta-lactams can participate. Key features: • Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures, CAS number, IUPAC names and associated biological activities • Offers a comprehensive collection of beta-lactamase databases, where the features of each database have been described • Explains the self-defense mechanisms of bacteria for surviving, including the formation of biofilm and conversion into L-form, as well as secretion of beta-lactamase to deactivate the beta-lactam antibiotics • Provides a comprehensive survey on the synthetic methods to make beta-lactams • Gives all of the possible reactions involving beta-lactams as the starting materials • Surveys over 1000 research works and includes all available DOI information The important information provided here will be a valuable resource on the antibiotic activities as well as chemical reactivities of beta-lactams for researchers and scientists, faculty, and advanced students, as well as for industry professionals working in medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, proteins and peptides."--
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