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The Characterisation Of A Novel Larval Drosophila Melanogaster Model Of Cancer Cachexia
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Book Synopsis The Drosophila Model in Cancer by : Wu-Min Deng
Download or read book The Drosophila Model in Cancer written by Wu-Min Deng and published by Springer Nature. This book was released on 2019-09-13 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression. Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use. This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems. This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.
Book Synopsis Drosophila Models for Human Diseases by : Masamitsu Yamaguchi
Download or read book Drosophila Models for Human Diseases written by Masamitsu Yamaguchi and published by Springer. This book was released on 2018-06-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis 17th Edition of the Spanish Society for Developmental Biology Meeting: New Trends in Developmental Biology by : Rosa Barrio
Download or read book 17th Edition of the Spanish Society for Developmental Biology Meeting: New Trends in Developmental Biology written by Rosa Barrio and published by Frontiers Media SA. This book was released on 2022-05-05 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hormones, Metabolism and the Benefits of Exercise by : Bruce Spiegelman
Download or read book Hormones, Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Book Synopsis Model Organisms in Drug Discovery by : Pamela M. Carroll
Download or read book Model Organisms in Drug Discovery written by Pamela M. Carroll and published by John Wiley & Sons. This book was released on 2004-04-21 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signalling pathways which "define" humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer’s disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems. Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future. Leading experts in the field provide detailed accounts of model organism research that have impacted on specific therapeutic areas and they examine state-of-the-art applications of model systems, describing real life applications and their possible impact in the future. This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.
Book Synopsis Animal Growth Regulation by : Dennis R. Campion
Download or read book Animal Growth Regulation written by Dennis R. Campion and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnological advances of recent years have put us on the brink of unprecedented gains in animal productivity. Manipulation of animal growth rate and composition of gain is now possible by a variety of techniques. Ex amples include ingestion of beta-adrenergic agonists, injection of somatotropin, castration, immunization, and gene insertion. Animal Growth Regulation ad dresses modem concepts of growth regulation with an emphasis on agricul turally important animals. This emphasis is not exclusive, as many situations exist in which the only information available was generated in other species, and this information has been included for the sake of clarity and completeness. However, because of the overall orientation of this volume, particular attention has been given to the regulation of skeletal muscle, adipose tissue, and bone growth. Certain hormones and growth factors have a profound influence on growth regulation and this basic physiological knowledge is being harnessed to maniplilate growth. Thus, considerable emphasis has been given to growth hor mone-somatomedinlinsulinlike growth factor regulation of cell and tissue growth. The involvement of peptides coded by protooncogenes and of negative growth regulators, such as transforming growth factor-l3, represents an emerging area of molecular biology wherein basic knowledge offers potential exploitation for growth manipulation. Opportunities also exist for regulation of protein turn over, especially from the standpoint of protein degradation. Therefore, a place was reserved for these topics in order to provide relevant basic knowledge.
Book Synopsis The Animal Parasites of Man by : Harold Benjamin Fantham
Download or read book The Animal Parasites of Man written by Harold Benjamin Fantham and published by . This book was released on 1916 with total page 946 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Life Extension by : Alexander M. Vaiserman
Download or read book Life Extension written by Alexander M. Vaiserman and published by Springer. This book was released on 2015-06-09 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in bio gerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans. Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of health span, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine. This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.
Book Synopsis Germline Stem Cells by : Michael Buszczak
Download or read book Germline Stem Cells written by Michael Buszczak and published by Humana. This book was released on 2016-10-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and new chapters on selected genetic, molecular, biochemical, and cell biological techniques. Chapter’s guide readers through methods and principles on primordial germ cells and germline stem cells, however many of these principles can be applied to different types of adult stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Germline Stem Cells: Second Edition aims to present the new findings and techniques that have developed since the first edition.
Book Synopsis Pathology, Prevention and Therapeutics of Neurodegenerative Disease by : Sarika Singh
Download or read book Pathology, Prevention and Therapeutics of Neurodegenerative Disease written by Sarika Singh and published by Springer. This book was released on 2018-09-24 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases
Book Synopsis Mild Stress and Healthy Aging by : Eric Le Bourg
Download or read book Mild Stress and Healthy Aging written by Eric Le Bourg and published by Springer Science & Business Media. This book was released on 2008-01-24 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can improve various biological parameters. This book brings together some of the world leaders in this area of research who present a critical analysis of the ongoing research with respect to the effects and mechanisms of action of various types of mild stress. Novel approaches to improving health and longevity are introduced.
Book Synopsis Foodborne Microbial Pathogens by : Arun K. Bhunia
Download or read book Foodborne Microbial Pathogens written by Arun K. Bhunia and published by Springer. This book was released on 2018-05-21 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book primarily covers the general description of foodborne pathogens and their mechanisms of pathogenesis, control and prevention, and detection strategies, with easy-to-comprehend illustrations. The book is an essential resource for food microbiology graduate or undergraduate students, microbiology professionals, and academicians involved in food microbiology, food safety, and food defense-related research or teaching. This new edition covers the significant progress that has been made since 2008 in understanding the pathogenic mechanism of some common foodborne pathogens, and the host-pathogen interaction. Foodborne and food-associated zoonotic pathogens, responsible for high rates of mortality and morbidity, are discussed in detail. Chapters on foodborne viruses, parasites, molds and mycotoxins, and fish and shellfish are expanded. Additionally, chapters on opportunistic and emerging foodborne pathogens including Nipah virus, Ebola virus, Aeromonas hydrophila, Brucella abortus, Clostridium difficile, Cronobacter sakazakii, and Plesiomonas shigelloides have been added. The second edition contains more line drawings, color photographs, and hand-drawn illustrations.
Download or read book Parasitology written by Alan Gunn and published by John Wiley & Sons. This book was released on 2012-04-30 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitology: An Integrated Approach, provides a concise, student-friendly account of parasites and parasite relationships that is supported by case studies and suggestions for student projects. The book focuses strongly on parasite interactions with other pathogens and in particular parasite-HIV interactions, as well as looking at how host behaviour contributes to the spread of infections. There is a consideration of the positive aspects of parasite infections, how humans have used parasites for their own advantage and also how parasite infections affect the welfare of captive and domestic animals. The emphasis of Parasitology is on recent research throughout and each chapter ends with a brief discussion of future developments. This text is not simply an updated version of typical parastitology books but takes an integrated approach and explains how the study of parasites requires an understanding of a wide range of other topics from molecular biology and immunology to the interactions of parasites with both their hosts and other pathogens.
Book Synopsis Antioxidant Properties of Spices, Herbs and Other Sources by : Denys J. Charles
Download or read book Antioxidant Properties of Spices, Herbs and Other Sources written by Denys J. Charles and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific world and modern society today is experiencing the dawning of an era of herbal medicine. Extensive research has shown that aromatic plants are important anti-inflammatory, antioxidant, anti aging and immune boosting delectable foods, with the magic and miracle to boost our immune system providing us with extended and an improved quality of life. Apart from making bland recipes into welcoming or interesting victories, herbs and spices have stirred the minds of the research community to look deeper into its active components from a functional perspective. It is essential to present the scientific and medicinal aspect of herbs and spices together with the analysis of constituents, its medicinal application, toxicology and its physiological effects. Herbs and spices with high levels of antioxidants are in great demand as they tend to promote health and prevent diseases naturally assuring increased safety and reliability for consumers. Herbs and spices are not only known for taste and flavor, but today research has opened up a new realm in which the antioxidant properties of these aromatic plants provide preservation for foods and health benefits for consumers who look forward to concrete scientific research to guide them further and explore herbal medicine. The aim of this book is to create awareness in society about the reliability of medicinal properties of certain herbs and spices through scientific and scholarly research.
Book Synopsis Essays on Developmental Biology Part B by : Paul Wassarman
Download or read book Essays on Developmental Biology Part B written by Paul Wassarman and published by Academic Press. This book was released on 2016-03-10 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or "golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. - Covers the area of developmental processes for a variety of model organisms - International board of authors - Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman
Book Synopsis Review of Medical Physiology by : William F. Ganong
Download or read book Review of Medical Physiology written by William F. Ganong and published by . This book was released on 1969 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
