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Author : Dolph O. Adams
Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.:/5 (31 download)
Download or read book The Cell Biology of Macrophage Activation written by Dolph O. Adams and published by . This book was released on 1984 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Khalid Hussain Bhat
Publisher : BoD – Books on Demand
ISBN 13 : 1789846447
Total Pages : 134 pages
Book Rating : 4.7/5 (898 download)
Download or read book Macrophage Activation written by Khalid Hussain Bhat and published by BoD – Books on Demand. This book was released on 2020-03-25 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are the sentinels of the immune system whose role has evolved beyond providing aseptic conditions to homeostasis, immune regulation, development, and behaviour. These cells have varied ontogenetic origins which reflects in their phenotypic and functional heterogeneity. Macrophage functions are fine-tuned by exogenous and endogenous signals and once tweaked, the information is included in their genetic makeup, albeit not indefinitely. Subversion of the macrophage functions is the hallmark of many pathogenic organisms and modulation of macrophage activity is pivotal to many therapeutic strategies. Fascinating and rapid developments in this field have necessitated the maintenance of currency of knowledge. This book provides a current account of information on varied topics in macrophage biology. Literature surveys have been presented in a captivating and lucid language. The contributing authors have also provided brief accounts of their own research. Every chapter provides a future perspective of what more could be achieved in the context of the current knowledge. The book will be of interest to students and researchers in microbiology, immunobiology, translational research, pathology, and related fields.
Author : Stephen W. Russell
Publisher : Springer Science & Business Media
ISBN 13 : 364277377X
Total Pages : 301 pages
Book Rating : 4.6/5 (427 download)
Download or read book Macrophage Biology and Activation written by Stephen W. Russell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amazing world of the mononuclear phagocytes keeps expanding at a truly awesome pace. As a result, maintaining currency with the latest developments and controversies that pertain to this cell type is increasingly difficult. The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future. The scope of topics ranges from how these cells develop, through the means that are used to regulate them, to the roles that they have in different tissues and in a variety of infectious diseases.
Author : David S. Nelson
Publisher : Academic Press
ISBN 13 : 1483274772
Total Pages : 652 pages
Book Rating : 4.4/5 (832 download)
Download or read book Immunobiology of the Macrophage written by David S. Nelson and published by Academic Press. This book was released on 2014-06-28 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book's contributors—immunologists of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.
Author : Dolph O. Adams
Publisher : Springer Science & Business Media
ISBN 13 : 1475714459
Total Pages : 276 pages
Book Rating : 4.4/5 (757 download)
Download or read book Macrophage Activation written by Dolph O. Adams and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gabriel Lopez-Berestein
Publisher : CRC Press
ISBN 13 : 9780849347061
Total Pages : 264 pages
Book Rating : 4.3/5 (47 download)
Download or read book Mononuclear Phagocytes in Cell Biology written by Gabriel Lopez-Berestein and published by CRC Press. This book was released on 1992-12-07 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mononuclear Phagocytes in Cell Biology provides a state-of-the-art review of the biological, biochemical, and molecular processes involved in macrophage activation. The book focuses on the role of macrophage "signals" in health and disease, which are discussed with particular attention to the physiological role of macrophages in homeostasis. The role played by macrophages in bone metabolism and the role of cytokines in diseases affecting the macrophage (e.g., HIV and leishmaniasis) are covered as well. The book also exploits the potential of macrophage "mimicry" as a therapeutic tool. Mononuclear Phagocytes in Cell Biology is a practical reference for cell biologists, medical microbiologists, molecular biologists, immunologists, hematologists, immunogeneticists, immunopharmacologists, and other basic and clinical researchers interested in macrophage development, biology, and differentiation.
Author : Claire E. Lewis
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Macrophage written by Claire E. Lewis and published by Oxford University Press, USA. This book was released on 1992 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, the study of immunology has focused to a large extent on the central role of antigen recognition and antibody structure and function in the response of the host to infection. In the last two decades, however, scientists have been turning their attention to the involvement of various cell types in host defense. This volume provides a collection of absorbing reviews written by expert scientists on this developing topic. A broad range of material is included relating to the molecular and cell biology of the macrophage and its host defence activity in human disease. The important role that these cells play in hemopoiesis and the functioning of the nervous system is also discussed. Advanced students and researchers in immunology, cell biology, and medicine will find The Macrophage a valuable source of current research into this emerging field.
Author : Sigurd J. Normann
Publisher : Springer Science & Business Media
ISBN 13 : 1468443941
Total Pages : 814 pages
Book Rating : 4.4/5 (684 download)
Download or read book Macrophages and Natural Killer Cells written by Sigurd J. Normann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the outcome of a meeting held in Davos, Switzerland, February 7-12, 1982 focused primarily on mononuclear phagocytes and on natural killer (NK) cells. This IX International RES Congress was attended by 489 scientists from 31 countries and there were 340 scientific presentations in oral or poster session. The essential purpose of the Congress was to bring together scientists representing various aspects of mononuclear phagocyte biology to review and examine cri~ically the effects and mechanisms of macrophage growth control as well as the participatio~ of these cells in the afferent and efferent limbs of the immune response. Additional topics included the production and distribution of mono nuclear phagocytes; the intrinsic and extrinsic regulation of these cells; and the origin, nature, function and regulation of NK cells. The ultimate goal of the Congress was to enhance communication between scientists in various countries and disciplines so that new research directives could be defined with which to explore basic aspects of macrophage and NK cell participation in the control of cancer and infection.
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Donna M. Paulnock
Publisher : OUP Oxford
ISBN 13 : 0191565784
Total Pages : 228 pages
Book Rating : 4.1/5 (915 download)
Download or read book Macrophages written by Donna M. Paulnock and published by OUP Oxford. This book was released on 2000-09-14 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are an important part of the immune response and are characterized by their ability to phagocytose foreign matter. However the difficulties involved in macrophage isolation mean they are some of the body's least explored cells. Macrophage Methodology describes how to isolate moderate to high yields of viable cells from a variety of specific tissue sites under both normal and pathological conditions and then goes on to give protocols for macrophage purification. The third chapter covers techniques used to identify and measure endocytic and phagocytic capabilities using immunochemistry and fluorescent analysis. Chapter four identifies the key issues relating to the study of macrophages as antigen presenting cells and has protocols for the major assays used to measure antigen processing and presentation. Also covered are the theoretical and practical issues related to the processing and presentation of intracellular pathogens for which macrophages are the major host cell. The methods described for measuring macrophage secretory products concentrate on bioassays for molecules where no ELISA is available. The next two chapters cover measuring macrophage activity in vitro and in vivo. Finally methods are described for the analysis of gene expression in macrophages. A variety of broad techniques have been brought together in one affordable volume to make Macrophage Methodology an essential buy for anyone studying macrophages.
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Robert D. Stout
Publisher : R. G. Landes
ISBN 13 : 9781570592713
Total Pages : 189 pages
Book Rating : 4.5/5 (927 download)
Download or read book T-cell Signaling of Macrophage Activation written by Robert D. Stout and published by R. G. Landes. This book was released on 1995-01-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tamás Röszer
Publisher : Springer Nature
ISBN 13 : 3030504808
Total Pages : 224 pages
Book Rating : 4.0/5 (35 download)
Download or read book The M2 Macrophage written by Tamás Röszer and published by Springer Nature. This book was released on 2020-08-03 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.
Author : Neil E. Reiner
Publisher : Humana Press
ISBN 13 : 9781627038492
Total Pages : 0 pages
Book Rating : 4.0/5 (384 download)
Download or read book Macrophages and Dendritic Cells written by Neil E. Reiner and published by Humana Press. This book was released on 2014-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the critical contributions of macrophages and dendritic cells to diverse inflammatory diseases and to immunity and host defense, state-of-the-art approaches to the investigation of their behavior are essential. In Macrophages and Dendritic Cells: Methods and Protocols, expert researchers contribute laboratory protocols involving these two vital cell types functioning at the junction of the innate and acquired immune systems. The volume delves first into isolation and cell culturing then continues with topics such as phagocytosis, genetic manipulation, macrophage activation, and lipid signaling. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Macrophages and Dendritic Cells: Methods and Protocols provides a timely and useful guide for both seasoned investigators and neophytes pursuing this imperative field of study.
Author : Liana Bolis
Publisher : Elsevier
ISBN 13 : 0323144691
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)
Download or read book Phagocytosis—past and future written by Liana Bolis and published by Elsevier. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phagocytosis—Past and Future is a collection of contributions by investigators who met in the Province of Messina, Sicily, in October 1980 to discuss the functions of phagocytic leukocytes in the host-parasite relationship. The topics discussed are largely in the areas of cell biology, cellular immunology, and biochemistry. They ranged from aspects of cellular movement and the ingestion process per se, to definition of substances that affect the function of phagocytic leukocytes and the nature of cidal mechanisms at the molecular level. This volume is organized into six sections encompassing 33 chapters and begins with an overview of Ilya Ilich Metchnikoff's life as well as his scientific contributions, particularly in the area of bacteriology and his research on mesodermal amoeboid cells. The next chapters focus on the mechanism of phagocytosis, with reference to aspects of cell membrane, cell movement, and ingestion. The reader is methodically introduced to the biochemical aspects of phagocytosis, from molecular modulations to energetics, oxygen radicals, and enzymes. The discussion then shifts to macrophages, their function in antigen recognition, receptor-mediated endocytosis in macrophage cell hybrids, and the role of phagocytosis in macrophage activation. The remaining chapters examine the cidal mechanisms of phagocytic leukocytes and aspects of inflammation. This book will be of interest to scientists and researchers in fields such as biology, biochemistry, immunology, pathology, pharmacology, and physiology.
Author : Stanley Cohen
Publisher : Academic Press
ISBN 13 : 1483271420
Total Pages : 645 pages
Book Rating : 4.4/5 (832 download)
Download or read book Biology of the Lymphokines written by Stanley Cohen and published by Academic Press. This book was released on 2013-09-17 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of the Lymphokines discusses the scope and diversity of lymphokine research. This book focuses on the studies on lymphokines, such as those involving cellular source, chemical nature, purification strategies, and bioassay limitations. The mechanism of lymphokine action, lymphokines in vivo, and value of lymphokine quantitations are also covered. This text describes the repertoire of lymphokines produced by various lymphoblastoid cell lines and its significance for coping with the problem of large scale lymphokine production. The anti-viral and general immunoregulatory properties of interferons and rationale developed for integrating interferons with the family of lymphokines are likewise deliberated. This publication is a good source for students and researchers conducting work on lymphokines.
Author : Malgorzata Kloc
Publisher : Springer
ISBN 13 : 3319540904
Total Pages : 375 pages
Book Rating : 4.3/5 (195 download)
Download or read book Macrophages written by Malgorzata Kloc and published by Springer. This book was released on 2017-04-26 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.
