The Catalyst Rna And The Quest To Unlock Lifes Deepest Secrets

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The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets

Author : Thomas R. Cech
Publisher : W. W. Norton & Company
ISBN 13 : 1324050691
Total Pages : 192 pages
Book Rating : 4.3/5 (24 download)

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Book Synopsis The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets by : Thomas R. Cech

Download or read book The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets written by Thomas R. Cech and published by W. W. Norton & Company. This book was released on 2024-06-04 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of Literary Hub's Most Anticipated Books of 2024 Exploring the most transformative breakthroughs in biology since the discovery of the double helix, a Nobel Prize–winning scientist unveils the RNA age. For over half a century, DNA has dominated science and the popular imagination as the “secret of life.” But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA—long overlooked as the passive servant of DNA—sits at the center of biology’s greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old? In The Catalyst, Cech finally brings together years of research to demonstrate that RNA is the true key to understanding life on Earth, from its very origins to our future in the twenty-first century. A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA’s spectacular powers, to Cech’s own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health. We learn how RNA—once thought merely to transmit DNA’s genetic instructions to the cell’s protein-making machinery—may have jump-started life itself, and how, at the same time, it can cut our individual lives short through viral diseases and cancer. We see how RNA is implicated in the aging process and explore the darker depths of the supposed fountain of youth, telomerase. And we catch a thrilling glimpse into how RNA-powered therapies—from CRISPR, the revolutionary tool that uses RNA to rewrite the code of life, to the groundbreaking mRNA vaccines that have saved millions during the pandemic, and more—may enable us to improve and even extend life beyond nature’s current limits. Written by one of our foremost scientists, The Catalyst is a must-read guide to the present and future of biology and medicine.

RNA

Author : James E. Darnell
Publisher :
ISBN 13 : 9781936113194
Total Pages : 0 pages
Book Rating : 4.1/5 (131 download)

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Book Synopsis RNA by : James E. Darnell

Download or read book RNA written by James E. Darnell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules could function as catalysts. --

Buzz Books2024: Spring/Summer

Author :
Publisher : Publishers Lunch
ISBN 13 : 1948586630
Total Pages : 1050 pages
Book Rating : 4.9/5 (485 download)

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Book Synopsis Buzz Books2024: Spring/Summer by :

Download or read book Buzz Books2024: Spring/Summer written by and published by Publishers Lunch. This book was released on 2024-01-16 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: Buzz Books 2024: Spring/Summer is the 24th volume in our popular sampler series. This Buzz Books presents passionate readers with an insider’s look at nearly sixty of the buzziest books due out this season. Such major bestselling authors as Ally Condie, Christina Dodd, and Emiko Jean are featured, along with literary figures like Mateo Askaripour, Abi Daré, Alison Espach, Peter Nichols and more. Buzz Books has had a particularly stellar track record with highlighting the most talented, exciting and diverse debut authors, and this edition is no exception. Rita Bullwinkel, editor at large for McSweeney’s and deputy editor of The Believer, offers a novel on women boxer, while Lily Samson’s title has already been preempted by Sony Pictures Television. One YA and two nonfiction authors make their adult fiction debuts: Kristen Perrin, Mary Annaïse Heglar and Kate Young, respectively. Among others are Essie Chambers, Katelyn Doyle, Alejandro Puyana, and Rachel Rueckert. Our robust nonfiction section covers such important subjects as suicide and combating racist biases; several memoirs about harrowing childhoods and illnesses; and a biography of the first Asian-American woman pilot to fly during World War II. Finally, we present early looks at new work from young adult authors, including the New York Times bestselling Tracey Baptiste and Morgan Matson. The YA titles also represent more diversity than ever, with Aboriginal, Chinese, Korean, Japanese, Malaysian and Trinidadian novelists. And be sure to look out for Buzz Books 2024: Fall/Winter, coming in May, for next season’s most talked about books.

Gene Machine

Author : Venki Ramakrishnan
Publisher : Basic Books
ISBN 13 : 046509337X
Total Pages : 290 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Gene Machine by : Venki Ramakrishnan

Download or read book Gene Machine written by Venki Ramakrishnan and published by Basic Books. This book was released on 2018-11-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

Catalyst

Author : Chandramouli Venkatesan
Publisher : Portfolio
ISBN 13 : 9780143442479
Total Pages : 208 pages
Book Rating : 4.4/5 (424 download)

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Book Synopsis Catalyst by : Chandramouli Venkatesan

Download or read book Catalyst written by Chandramouli Venkatesan and published by Portfolio. This book was released on 2018-02-15 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: A good job, hard work, IQ, EQ, good communication skills-these are all ingredients for a successful life. The presence of these elements alone, however, does not guarantee success. To convert them into long-term success, you need certain stimuli which precipitate or accelerate your growth. This robustly effective book identifies the various catalysts that you can cultivate and how you can leverage them to propel yourself in your work and life. Accessible, engaging and easy to follow, and written by someone who has experienced all this in real life and not in theory, Catalyst will arm you with the right tools to succeed at your work place and get the most out of every moment, every day.

Lehninger Principles of Biochemistry

Author : Albert L. Lehninger
Publisher : Macmillan
ISBN 13 : 9780716743392
Total Pages : 1256 pages
Book Rating : 4.7/5 (433 download)

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Book Synopsis Lehninger Principles of Biochemistry by : Albert L. Lehninger

Download or read book Lehninger Principles of Biochemistry written by Albert L. Lehninger and published by Macmillan. This book was released on 2005 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: CD-ROM includes animations, living graphs, biochemistry in 3D structure tutorials.

The Antidote

Author : Barry Werth
Publisher : Simon and Schuster
ISBN 13 : 1451655665
Total Pages : 448 pages
Book Rating : 4.4/5 (516 download)

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Book Synopsis The Antidote by : Barry Werth

Download or read book The Antidote written by Barry Werth and published by Simon and Schuster. This book was released on 2014-02-04 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.

The Quest for a Universal Theory of Life

Author : Carol E. Cleland
Publisher : Cambridge University Press
ISBN 13 : 052187324X
Total Pages : 261 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis The Quest for a Universal Theory of Life by : Carol E. Cleland

Download or read book The Quest for a Universal Theory of Life written by Carol E. Cleland and published by Cambridge University Press. This book was released on 2019-09-12 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores fundamental philosophical and scientific questions about the nature of life, particularly in relation to the search for extraterrestrial life.

Red Pill

Author : Hari Kunzru
Publisher : Vintage
ISBN 13 : 0451493729
Total Pages : 305 pages
Book Rating : 4.4/5 (514 download)

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Book Synopsis Red Pill by : Hari Kunzru

Download or read book Red Pill written by Hari Kunzru and published by Vintage. This book was released on 2020-09-01 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: ONE OF THE NEW YORK TIMES'S 100 NOTABLE BOOKS OF 2020 ONE OF NPR's BEST BOOKS OF 2020 ONE OF THE A.V. CLUB'S 15 FAVORITE BOOKS OF 2020 From the widely acclaimed author of White Tears, a bold new novel about searching for order in a world that frames madness as truth. After receiving a prestigious writing fellowship in Germany, the narrator of Red Pill arrives in the Berlin suburb of Wannsee and struggles to accomplish anything at all. Instead of working on the book he has proposed to write, he takes long walks and binge-watches Blue Lives--a violent cop show that becomes weirdly compelling in its bleak, Darwinian view of life--and soon begins to wonder if his writing has any value at all. Wannsee is a place full of ghosts: Across the lake, the narrator can see the villa where the Nazis planned the Final Solution, and in his walks he passes the grave of the Romantic writer Heinrich von Kleist, who killed himself after deciding that "no happiness was possible here on earth." When some friends drag him to a party where he meets Anton, the creator of Blue Lives, the narrator begins to believe that the two of them are involved in a cosmic battle, and that Anton is "red-pilling" his viewers--turning them toward an ugly, alt-rightish worldview--ultimately forcing the narrator to wonder if he is losing his mind.

Secret Life

Author : Michael Ryan
Publisher : Vintage
ISBN 13 : 9780679767763
Total Pages : 0 pages
Book Rating : 4.7/5 (677 download)

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Book Synopsis Secret Life by : Michael Ryan

Download or read book Secret Life written by Michael Ryan and published by Vintage. This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the age of five, Michael Ryan was molested by a neighbor. Nearly 40 years later, he found himself methodically preparing to seduce a girl who was barely more than a child. As Ryan describes his free fall into sexual obsession, he creates an autobiography that is at once harrowing and redemptive, heartbreaking and profoundly moral. "By turns repelling and seductive . . . absorbing and disquieting."--New York Times Book Review.

RNA Methodologies

Author : Robert E. Farrell Jr.
Publisher : Elsevier
ISBN 13 : 0080454763
Total Pages : 794 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis RNA Methodologies by : Robert E. Farrell Jr.

Download or read book RNA Methodologies written by Robert E. Farrell Jr. and published by Elsevier. This book was released on 2010-07-22 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: This laboratory guide represents a growing collection of tried, tested and optimized laboratory protocols for the isolation and characterization of eukaryotic RNA, with lesser emphasis on the characterization of prokaryotic transcripts. Collectively the chapters work together to embellish the RNA story, each presenting clear take-home lessons, liberally incorporating flow charts, tables and graphs to facilitate learning and assist in the planning and implementation phases of a project. RNA Methodologies, 3rd edition includes approximately 30% new material, including chapters on the more recent technologies of RNA interference including: RNAi; Microarrays; Bioinformatics. It also includes new sections on: new and improved RT-PCR techniques; innovative 5’ and 3’ RACE techniques; subtractive PCR methods; methods for improving cDNA synthesis. * Author is a well-recognized expert in the field of RNA experimentation and founded Exon-Intron, a well-known biotechnology educational workshop center * Includes classic and contemporary techniques * Incorporates flow charts, tables, and graphs to facilitate learning and assist in the planning phases of projects

Strengthening Forensic Science in the United States

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309142393
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Strengthening Forensic Science in the United States by : National Research Council

Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.

The Mystery of Life's Origin

Author : Charles B. Thaxton
Publisher :
ISBN 13 : 9781936599745
Total Pages : 486 pages
Book Rating : 4.5/5 (997 download)

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Book Synopsis The Mystery of Life's Origin by : Charles B. Thaxton

Download or read book The Mystery of Life's Origin written by Charles B. Thaxton and published by . This book was released on 2020-01-27 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin of life from non-life remains one of the most enduring mysteries of modern science. This book investigates how close scientists are to solving that mystery and explores what we are learning about the origin of life from current research in chemistry, physics, astrobiology, biochemistry, and more.

Atomic Evidence

Author : David S. Goodsell
Publisher : Springer
ISBN 13 : 3319325108
Total Pages : 182 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Atomic Evidence by : David S. Goodsell

Download or read book Atomic Evidence written by David S. Goodsell and published by Springer. This book was released on 2016-08-04 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. The book will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.

Family Secrets

Author : David Leitch
Publisher : Heinemann
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Family Secrets by : David Leitch

Download or read book Family Secrets written by David Leitch and published by Heinemann. This book was released on 1984 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Hadal Zone

Author : Alan Jamieson
Publisher : Cambridge University Press
ISBN 13 : 1316060721
Total Pages : 397 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis The Hadal Zone by : Alan Jamieson

Download or read book The Hadal Zone written by Alan Jamieson and published by Cambridge University Press. This book was released on 2015-01-29 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hadal zone represents one of the last great frontiers in marine science, accounting for 45% of the total ocean depth range. Despite very little research effort since the 1950s, the last ten years has seen a renaissance in hadal exploration, almost certainly as a result of technological advances that have made this otherwise largely inaccessible frontier, a viable subject for research. Providing an overview of the geology involved in trench formation, the hydrography and food supply, this book details all that is currently known about organisms at hadal depths and linkages to the better known abyssal and bathyal depths. New insights on how, where and what really survives and thrives in the deepest biozone are provided, allowing this region to be considered when dealing with sustainability and conservation issues in the marine environment.

A Crack In Creation

Author : Jennifer A. Doudna
Publisher : HarperCollins
ISBN 13 : 0544716965
Total Pages : 307 pages
Book Rating : 4.5/5 (447 download)

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Book Synopsis A Crack In Creation by : Jennifer A. Doudna

Download or read book A Crack In Creation written by Jennifer A. Doudna and published by HarperCollins. This book was released on 2017-06-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY | Finalist for the Los Angeles Times Book Prize “A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “An invaluable account . . . We owe Doudna several times over.” — Guardian