The B-Side of B Cells

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Publisher : Frontiers Media SA
ISBN 13 : 2889715205
Total Pages : 113 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The B-Side of B Cells by : Maria Manuela Rosado

Download or read book The B-Side of B Cells written by Maria Manuela Rosado and published by Frontiers Media SA. This book was released on 2021-10-21 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Janeway's Immunobiology

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Author :
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular Biology of B Cells

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Publisher : Academic Press
ISBN 13 : 9780123979339
Total Pages : 0 pages
Book Rating : 4.9/5 (793 download)

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Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo

Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.

B Cell Receptor Signaling

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Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 231 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis B Cell Receptor Signaling by : Tomohiro Kurosaki

Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

B Cells in Immunity and Tolerance

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Publisher : Springer
ISBN 13 : 9789811535345
Total Pages : 181 pages
Book Rating : 4.5/5 (353 download)

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Book Synopsis B Cells in Immunity and Tolerance by : Ji-Yang Wang

Download or read book B Cells in Immunity and Tolerance written by Ji-Yang Wang and published by Springer. This book was released on 2021-05-07 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

Normal and Malignant B-Cell

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 178985430X
Total Pages : 163 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Normal and Malignant B-Cell by : Mourad Aribi

Download or read book Normal and Malignant B-Cell written by Mourad Aribi and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book will be interesting and useful for clinicians, biologists, researchers, teachers, and graduate students of both doctoral and master's degrees in the field of immunology.

B Cell Protocols

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597963
Total Pages : 294 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis B Cell Protocols by : Hua Gu

Download or read book B Cell Protocols written by Hua Gu and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming and often very difficult for a student or just any bench-side worker to identify a reliable experimental protocol in the ocean of the literature. The aim of B Cell Protocols is to provide a collection of diverse protocols ranging from the latest inventions and applications to some classic, but still frequently used methods in B-cell biology. The authors of the various chapters are all highly qualified scientists who are either the inventors or expert users of these methods. Their extensive experience in mastering a particular method provides not only the step-by-step details of a reproducible protocol, but also useful troubleshooting tips that readers will appreciate in their daily work. We hope that this book will be helpful for both beginning and experienced researchers in the field in designing or modifying an experimental approach, and exploring a biological question from multiple angles.

Lymphocyte Updates

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Publisher : BoD – Books on Demand
ISBN 13 : 9535133438
Total Pages : 194 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Lymphocyte Updates by : Gheorghita Isvoranu

Download or read book Lymphocyte Updates written by Gheorghita Isvoranu and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a synergic effort of an international team of specialists in immunology to expand the scientific achievements in the field of lymphocytes. It offers important and specific updated information to researchers, students, teachers, and medical professionals. Moreover, considering the remarkable dynamics of immunology and immunotherapy, this book "Lymphocyte Updates - Cancer, Autoimmunity, and Infection" aims to represent a significant source of concise scientific data and advancement of knowledge in this field. The chapters offer new insights into the latest scientific progress on lymphocyte roles in protective immunity, as well as their involvement in pathogenesis of various disorders.

Molecular Biology of B Cells

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Publisher : Elsevier
ISBN 13 : 9780080479507
Total Pages : 600 pages
Book Rating : 4.4/5 (795 download)

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Book Synopsis Molecular Biology of B Cells by : Michael Reth

Download or read book Molecular Biology of B Cells written by Michael Reth and published by Elsevier. This book was released on 2004-02-19 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.

New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Disease Biology and Signaling

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889742415
Total Pages : 164 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Disease Biology and Signaling by : Jérôme Paggetti

Download or read book New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Disease Biology and Signaling written by Jérôme Paggetti and published by Frontiers Media SA. This book was released on 2022-01-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

B Lymphocytes in Human Disease

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Publisher :
ISBN 13 :
Total Pages : 554 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis B Lymphocytes in Human Disease by : Angus Graham Bird

Download or read book B Lymphocytes in Human Disease written by Angus Graham Bird and published by . This book was released on 1988 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past two decades, cells of the B-lymphocyte lineage have been the subject of intensive research. B-lymphocytes and antibodies play a crucial role in the body's defense against infection, but can also be responsible for producing certain diseases. This volume provides an up-to-date discussion of the cellular and molecular biology of antibodies and the cells that produce them. Researchers discuss the fundamentals of B-cell biology that are crucial to understanding how cells and their antibody products generate a range of malignant, autoimmune and immunodeficiency disorders. The discussion of human diseases in the second part of the book provides an interface between recent advances in B-cell biology and B-cell related disease processes.

B Cell Activation and Differentiation: New Perspectives on an Enduring Topic

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Publisher : Frontiers Media SA
ISBN 13 : 2889719588
Total Pages : 213 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis B Cell Activation and Differentiation: New Perspectives on an Enduring Topic by : Zhenming Xu

Download or read book B Cell Activation and Differentiation: New Perspectives on an Enduring Topic written by Zhenming Xu and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Humoral Primary Immunodeficiencies

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Publisher : Springer
ISBN 13 : 3319917854
Total Pages : 383 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Humoral Primary Immunodeficiencies by : Mario Milco D'Elios

Download or read book Humoral Primary Immunodeficiencies written by Mario Milco D'Elios and published by Springer. This book was released on 2018-12-29 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.e., disorders arising from impaired antibody production due to defects intrinsic to B cells or defective interaction between B and T cells. There is extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the B cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel humoral PID genes and related clinical applications, mucosal B cells, and the various clinical phenotypes of humoral PIDs. Aspects such as differential diagnosis, clinical management in children and adults, and the role of vaccines are also addressed. The authors are all recognized experts from Europe, Australia, and the United States. Humoral Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD and PhD students.

Antibodies

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Publisher : Springer Science & Business Media
ISBN 13 : 1461318734
Total Pages : 208 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Antibodies by : A. Szentivanyi

Download or read book Antibodies written by A. Szentivanyi and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is based on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their structure, synthesis, function, and clinical applicability in disease. Organization of this symposium by the University of South Florida College of Medicine was prompted by the unparalleled current expansion of information on these topics in general, and in the field of antibody diver sity, in particular. The issues that surround the last named dimension of this field, began to surface in the late 1950's with the first conclusive genetic studies having been answered, and a new set of concepts has been de fined. As we see it from the material presented in this volume, now new and different questions are being raised and answered by studies in progress, and it may be expected that there will be other questions that will be with us for a considerably longer time. We believe that the symposium brought together many prominent investi gators with different backgrounds and training experiences such as immunolo gists, microbiologists, biochemists, molecular biologists, and clinical sci entists, thus providing an excellent example of the interdisciplinary value of modern immunology and modern biomedical science in general. We believe, therefore, that bringing these complex topics to a wide audience of bio medical scientists through this symposium as well as this volume is of value to the scientific and to the medical community.

B Cell Biology in Autoimmunity

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805574541
Total Pages : 281 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis B Cell Biology in Autoimmunity by : David Ahmad Nemazee

Download or read book B Cell Biology in Autoimmunity written by David Ahmad Nemazee and published by Karger Medical and Scientific Publishers. This book was released on 2003 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: B cells play a central role not only in adaptive immunity, but also in autoimmunity. To understand how B cells are normally prevented from reacting to self-tissue, what goes wrong in autoimmunity, and how B cells contribute to it is the aim of this book. This volume includes more than a dozen in-depth reviews by researchers specializing in various aspects of basic B cell biology that have relevance to autoimmune diseases. These up-to-date chapters present the latest information on B cell signal transduction, apoptosis, genetics and molecular biology. Also featured are chapters with special reference to particular autoimmune diseases in which B cells have been shown to play a critical role, such as type 1 diabetes, chronic graft-versus-host disease and lupus erythematosus. Further topics covered include the role of the complement system, rheumatoid factors, and anti-DNA autoantibodies as well as important related areas such as natural autoantibodies, B cell immune tolerance, Toll receptor signaling, and the immunobiology of BAFF/BLyS. Both basic researchers and clinician scientists who wish to understand the role of B lymphocytes in immune tolerance and autoimmunity will benefit from this timely publication.

B Lymphocytes

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis B Lymphocytes by : G. G. B. Klaus

Download or read book B Lymphocytes written by G. G. B. Klaus and published by Oxford University Press, USA. This book was released on 1990 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely review of our current knowledge of the cellular and molecular biology of B lymphocytes. These cells play a key role in the immune system. B cells recognize antigens by means of specific cell surface antibody molecules, and in recent years there has been rapid progress in our understanding of these responses. Considerable advances have also been made in unravelling the regulation of B cell activation by T cells and the cytokines they produce, and how microenvironmental factors determine whether B cells become antibody-producing cell or memory cells. Intended for undergraduates and graduate students in biology and medicine, this work covers new topics and ideas not adequately covered in existing textbooks. It provides in-depth knowledge in an easy-to-read format, with two-color diagrams for increased clarity.

Humanized Mice for HIV Research

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Author :
Publisher : Springer
ISBN 13 : 1493916556
Total Pages : 538 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Humanized Mice for HIV Research by : Larisa Y. Poluektova

Download or read book Humanized Mice for HIV Research written by Larisa Y. Poluektova and published by Springer. This book was released on 2015-02-18 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. Humanized Mice for HIV Research provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An expansion of twelve review articles that were published in Humanized Mice by Springer in 2008 (Eds: Nomura T, Watanabe T, Habu S), this book expertly captures the outstanding progress that has been made in the development, improvement, implementation, and validation of humanized mouse models. The first two parts of this book cover the basics of human-to-mouse xenotransplantation biology, and provide critical information about human immune cell development and function based on individual models created from different immunodeficient strains of mice. The third and fourth parts investigate HIV-1 biology, including different routes of transmission, prevention, treatment, pathogenesis, and the development of adaptive immunity in humanized mice. The fifth part shows the broad applicability of humanized mice for therapeutic development, from long-acting antiretroviral combinations to genetic manipulations with human cells and cell-based approaches. The sixth part includes liver tissue engineering and the expansion of humanized mice for many other human cell-tropic pathogens.