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The Anti Obesity Effects Of Dietary Trans Trans Conjugated Linoleic Acid Rich Soy Oil In Obese Zucker Rats
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Book Synopsis The Anti-obesity Effects of Dietary Trans-trans Conjugated Linoleic Acid-rich Soy Oil in Obese Zucker Rats by : William Clayton Gilbert
Download or read book The Anti-obesity Effects of Dietary Trans-trans Conjugated Linoleic Acid-rich Soy Oil in Obese Zucker Rats written by William Clayton Gilbert and published by . This book was released on 2010 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Stearidonic Acid-enriched Soybean Oil on Metabolic Profile and Fatty Acid Composition in Lean and Obese Zucker Rats by : John Casey
Download or read book Effects of Stearidonic Acid-enriched Soybean Oil on Metabolic Profile and Fatty Acid Composition in Lean and Obese Zucker Rats written by John Casey and published by . This book was released on 2013 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background, Consumption of marine-based oils high in omega-3 polyunsaturated fatty acids (n3PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is known to protect against obesity-related pathologies. It is less clear whether traditional vegetable oils with high omega-6 polyunsaturated fatty acid (n6PUFA) content exhibit similar therapeutic benefits. As such, this study examined the metabolic effects of a plant-based n3PUFA, stearidonic acid (SDA), in polygenic obese rodents. Methods, Lean (LZR) and obese Zucker (OZR) rats were provided either a standard westernized control diet (CON) with a high n6PUFA to n3PUFA ratio (i.e., 16.2/1.0) or experimental diet modified with flaxseed (FLAX), menhaden (FISH), or SDA oil that resulted in n6PUFA to n3PUFA ratios of 1.7/1.0, 1.3/1.0, and 1.0/0.8, respectively. Results, After 12 weeks, total adiposity, dyslipidemia, glucose intolerance, and hepatic steatosis were all greater, whereas n3PUFA content in liver, adipose, and muscle was lower in OZR vs. LZR rats. Obese rodents fed modified FISH or SDA diets had lower serum lipids and hepatic fat content vs. CON. The omega-3 index (i.e., ÓEPA + DHA in erythrocyte membrane) was 4.0, 2.4, and 2.0-fold greater in rodents provided FISH, SDA, and FLAX vs. CON diet, irrespective of genotype. Total hepatic n3PUFA and DHA was highest in rats fed FISH, whereas both hepatic and extra-hepatic EPA was higher with FISH and SDA groups. Conclusions, these data indicate that SDA oil represents a viable plant-derived source of n3PUFA, which has therapeutic implications for several obesity-related pathologies.
Book Synopsis Effects of Dietary Gamma-linolenic Acid on Somatic and Central Nervous System Fatty Acid Composition in Lean (Fa/Fa) and Obese (fa/fa) Zucker Rats by : Debbie Carolyn Thurmond
Download or read book Effects of Dietary Gamma-linolenic Acid on Somatic and Central Nervous System Fatty Acid Composition in Lean (Fa/Fa) and Obese (fa/fa) Zucker Rats written by Debbie Carolyn Thurmond and published by . This book was released on 1992 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Update on Trans Fatty Acids and Health by : Great Britain. Scientific Advisory Committee on Nutrition
Download or read book Update on Trans Fatty Acids and Health written by Great Britain. Scientific Advisory Committee on Nutrition and published by Stationery Office Books (TSO). This book was released on 2007 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current guideline for the consumption of trans fatty acids (trans FA) is that they should not exceed 2% of food energy. Due to health concerns, the Food Standards Agency was asked to consider the case for a reduction in this recommendation to less than 1% and the Scientific Advisory Committee on Nutrition has thus tasked with examining recent scientific evidence on the health effects of trans FA. It concludes that there is consistent evidence to support a moderate effect of trans FA on increasing the risk of coronary heart disease but evidence related to other diseases is limited and no reliable risk assessment can be made. There is however no firm scientific basis for a change in the current recommendation of not exceeding 2% of food energy. There is also insufficient evidence to justify the differentiation of trans FA from vegetable oil and animal sources.
Book Synopsis The Effect of Dietary Alpha-linolenic Acid-rich Flaxseed Oil Intervention on Immune and Adipose Tissue Function in Obese Zucker Rats by : Maria Baranowski
Download or read book The Effect of Dietary Alpha-linolenic Acid-rich Flaxseed Oil Intervention on Immune and Adipose Tissue Function in Obese Zucker Rats written by Maria Baranowski and published by . This book was released on 2009 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Anti-obesity Mechanisms of Conjugated Linoleic Acid (CLA) by : Wan Shen
Download or read book Anti-obesity Mechanisms of Conjugated Linoleic Acid (CLA) written by Wan Shen and published by . This book was released on 2015 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Overweight and obesity are the most widespread nutritional diseases in the U.S., which greatly increase chronic disease risks and mortality. Therefore, it is urgent to develop a relatively efficacious and safe strategy for the weight management. Consumption of conjugated linoleic acid (CLA) supplements or one of its isomers, trans-10, cis-12 (10,12) CLA, has consistently demonstrated reductions in body weight or body fat in human and animal studies. Our lab has demonstrated that 10,12 CLA triggered calcium release from endoplasmic reticulum in human primary adipocytes, which activated downstream inflammatory signaling, resulting in impaired uptake of glucose and fatty acid, and delipidation. However, the upstream signals responsible for these actions are unknown. Therefore, my Aim 1 investigated the upstream mechanism by which 10,12 CLA increases intracellular calcium and inflammatory signaling in human primary adipocytes. The results indicated that phospholipase C plays an important role in 10,12 CLA-mediated activation of intracellular calcium accumulation, inflammatory signaling, delipidation, and insulin resistance in human primary adipocytes. It has been demonstrated that 10,12 CLA increased mRNA levels and protein levels of cyclooxygenase-2 (COX-2) and pro-inflammatory prostaglandins, which have been linked to increased energy expenditure associated with white adipose tissue (WAT) browning and uncoupling of ATP synthesis. It also has been shown that relatively high doses of 10,12 CLA lead to more significant reductions in body fat, but cause a greater level of inflammation, insulin resistance, and steatosis in animals. Therefore, Aims 2 and Aim 3 determined the extent to which a relative low dose of 10,12 CLA or a CLA isomer mixture increases markers of browning in mice and its dependence in inflammatory signaling. In Aim 2, a low threshold dose of 10,12 CLA was found that prevented body fat accumulation with minimum metabolic side-effects in non-obese mice. It was also found that 10,12 CLA-induced browning in WAT was accompanied by increases in mRNA levels of COX-2 and other markers of inflammation. In Aim 3, a relatively low dose of 10,12 CLA reduced body fat and increased browning of WAT in overweight mice, which were independent of inflammatory signaling. Collectively, these findings provide critical insights for the development of reliable dietary strategies for people who take CLA as method to lose weight. However, we still do not know (i) if 10,12 CLA supplementation would effectively reduce body fat in overweight mice when they are continuously fed an American-type, high-fat diet; (ii) potential risks of impaired regulation of body temperature, inflammation, and steatosis due to 10,12 CLA consumption in high fat-fed mice; and (iii) potential mechanisms by which 10,12 CLA reduces body fat in high fat-fed mice."--Abstract from author supplied metadata.
Book Synopsis Metabolic Syndrome by : Satinath Mukhopadhyay
Download or read book Metabolic Syndrome written by Satinath Mukhopadhyay and published by Academic Press. This book was released on 2023-11-10 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Syndrome: From Mechanisms to Interventions covers all aspects of this complex and multifactorial disease, providing a cutting-edge understanding of the problem of MetS, with a particular focus on its prevention and clinical management. The book discusses practical implementable approaches to its reversal in clinical practice, encompassing the entire spectrum of MetS, from molecular understanding to clinical therapeutics and prevention. This book is a valuable resource for clinicians in multiple specialties, including endocrinologists, diabetologists, hepatologists, gynecologists and researchers in related fields who need a deep understanding of the full range of scientific and clinical aspects of metabolic syndrome. Presents a holistic, preventative strategy involving each and every aspect of metabolic syndrome, from pathophysiologic to clinical management Discusses recent research on the role of inflammation, adipokines and myokines in metabolic syndrome Includes cutting-edge information on the impact of bariatric surgery and role of gut microbiota in MetS Provides flowcharts and diagrams to simplify pathophysiologic aspects and their association between risk factors
Book Synopsis Effects of Dietary Trans-10, Cis-12 Conjugated Linoleic Acid on Food Intake and Body Weight Regulation Via Central and Peripheral Mechanisms by : Hon-Hon So
Download or read book Effects of Dietary Trans-10, Cis-12 Conjugated Linoleic Acid on Food Intake and Body Weight Regulation Via Central and Peripheral Mechanisms written by Hon-Hon So and published by . This book was released on 2017-01-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Dietary Hydrogenated Soybean Oil Upon Rat Dams and Offspring by : Robert Frederic Borgman
Download or read book Effects of Dietary Hydrogenated Soybean Oil Upon Rat Dams and Offspring written by Robert Frederic Borgman and published by . This book was released on 1979 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Trans 10, CIS 12 Conjugated Linoleic Acid (T10, C12 CLA) is the Isomer Responsible for the Beneficial Effect of Dietary CLA in the Kidneys of Obese, Insulin-resistant Rats by : Dielle Janet Herchak
Download or read book Trans 10, CIS 12 Conjugated Linoleic Acid (T10, C12 CLA) is the Isomer Responsible for the Beneficial Effect of Dietary CLA in the Kidneys of Obese, Insulin-resistant Rats written by Dielle Janet Herchak and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Adiposity by Dietary Conjugated Linoleic Acid by : Xiaofang Xu
Download or read book Regulation of Adiposity by Dietary Conjugated Linoleic Acid written by Xiaofang Xu and published by . This book was released on 2002 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Effect of a Soy Protein Diet on Attenuation of Obesity-related Pathologies in Obese Zucker Rats by : James Cain
Download or read book The Effect of a Soy Protein Diet on Attenuation of Obesity-related Pathologies in Obese Zucker Rats written by James Cain and published by . This book was released on 2010 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Conjugated Linoleic Acid Isomers on Eicosanoid Metabolism in Kidney and Liver Tissues of Obese Zucker Rats by : Hong Shi
Download or read book Effects of Conjugated Linoleic Acid Isomers on Eicosanoid Metabolism in Kidney and Liver Tissues of Obese Zucker Rats written by Hong Shi and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: CLA -- Zucker rat -- eicosanoids -- tissues.
Book Synopsis Effects of Dietary TRANS-10, CIS-12 Conjugated Linoleic Acid on Food Intake and Body Weight Regulation Via Central and Peripheral Mechanisms by : Hon-hon So
Download or read book Effects of Dietary TRANS-10, CIS-12 Conjugated Linoleic Acid on Food Intake and Body Weight Regulation Via Central and Peripheral Mechanisms written by Hon-hon So and published by . This book was released on 2009 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Effect of Dietary Triglyceride Chain Length on Obesity in Rats Fed High Fat Diets by : Joanne Huseman Fino
Download or read book The Effect of Dietary Triglyceride Chain Length on Obesity in Rats Fed High Fat Diets written by Joanne Huseman Fino and published by . This book was released on 1973 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Treatment Effects of Dietary Oils on Diet-induced Obesity, Lipidemia, and Insulin Resistance in Skeletal Muscle Tissue of Obese Prone Rats by : Karin Dunthorne
Download or read book The Treatment Effects of Dietary Oils on Diet-induced Obesity, Lipidemia, and Insulin Resistance in Skeletal Muscle Tissue of Obese Prone Rats written by Karin Dunthorne and published by . This book was released on 2011 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity -- Metabolism -- Nutrition -- Diabetes -- Canola -- Oil.
Book Synopsis The Effect of Dietary Conjugated Linoleic Acid on Growth, Body Composition, and Immune Status in the Rat by : Matthew Sisk
Download or read book The Effect of Dietary Conjugated Linoleic Acid on Growth, Body Composition, and Immune Status in the Rat written by Matthew Sisk and published by . This book was released on 1999 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
