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Author : Mohammad Amjad Kamal
Publisher : Frontiers Media SA
ISBN 13 : 2832514200
Total Pages : 223 pages
Book Rating : 4.8/5 (325 download)
Download or read book The alzheimer’s disease challenge, volume II written by Mohammad Amjad Kamal and published by Frontiers Media SA. This book was released on 2023-02-09 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mohammad Amjad Kamal
Publisher : Frontiers Media SA
ISBN 13 : 2832547737
Total Pages : 202 pages
Book Rating : 4.8/5 (325 download)
Download or read book The Alzheimer's Disease Challenge, Volume II written by Mohammad Amjad Kamal and published by Frontiers Media SA. This book was released on 2024-04-15 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II: “The Alzheimer's Disease Challenge”. The repeated failure of clinical trials on the amyloid-based medications and the pessimistic calculations of Alzheimer's disease cost burden for the next few decades present a severe challenge to humankind with severe social implications. In recent years, several alternative diagnostic and treatment procedures have been presented to treat and manage Alzheimer’s disease as it has been nearly impossible to suggest a holistic solution. Several revelations in human biology have highlighted the multiparametric character of the disease. Besides the amyloid aggregation and neurofibrillary tangles that result in Aβ toxicity and tau phosphorylation, processes such as Gene Mutations, Proteins Misfolding, Brain Biochemical and Histopathological Changes, Behavioral Changes, Nutrition and Metabolism Alterations, and Autonomic Dysfunctions due to Central Nervous System dysregulations are common signs and probably early diagnostic biomarkers in most of the Alzheimer's classification categories.
Author : Athanasios Alexiou
Publisher : Frontiers Media SA
ISBN 13 : 2889631281
Total Pages : 501 pages
Book Rating : 4.8/5 (896 download)
Download or read book The Alzheimer's Disease Challenge written by Athanasios Alexiou and published by Frontiers Media SA. This book was released on 2019-12-04 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
Author : Menghis Bairu
Publisher : Academic Press
ISBN 13 : 0124115306
Total Pages : 428 pages
Book Rating : 4.1/5 (241 download)
Download or read book Global Clinical Trials for Alzheimer's Disease written by Menghis Bairu and published by Academic Press. This book was released on 2013-08-28 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease. Written by leading experts with hands-on experience in designing and running global Alzheimer’s disease and other neurodegenerative diseases clinical trials A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer’s disease global clinical trials in emerging markets and developing countries
Author : Inga Zerr
Publisher : BoD – Books on Demand
ISBN 13 : 9535121375
Total Pages : 374 pages
Book Rating : 4.5/5 (351 download)
Download or read book Alzheimer's Disease written by Inga Zerr and published by BoD – Books on Demand. This book was released on 2015-07-01 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role of lipids and cholesterol has been recognized, but the relevant pathogenetic steps are still to be identified. There is an urgent need to understand molecular disease pathogenesis in order to develop early therapeutic targets for the disease.
Author : Jolanta Dorszewska
Publisher : BoD – Books on Demand
ISBN 13 : 178923462X
Total Pages : 164 pages
Book Rating : 4.7/5 (892 download)
Download or read book Alzheimer's Disease written by Jolanta Dorszewska and published by BoD – Books on Demand. This book was released on 2018-07-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical activity. Moreover, it describes the therapies used in Alzheimer's disease to slow the progression of the disease and delay its onset. Subsequently, the authors discuss experimental and clinical trials used now and in the near future. We hope that this book will help the readers to understand the complex mechanism leading to the development of Alzheimer's disease and indicate effective ways to prevent this disorder.
Author : Hilary W. Poole
Publisher : AV2 by Weigl
ISBN 13 : 9781489679406
Total Pages : 0 pages
Book Rating : 4.6/5 (794 download)
Download or read book Alzheimer's Disease written by Hilary W. Poole and published by AV2 by Weigl. This book was released on 2018-07-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are all forgetful sometimes. As people age, they can become more forgetful still. But when remembering information becomes a daily struggle, a person might be suffering from a condition called Alzheimer's disease. Alzheimer's has been called "the thief," because it steals away the person you loved. Knowing someone with this disease can be hard, but there are ways to encourage your loved ones and help them live happily. The lives of millions of kids are affected by mental illness. And yet it's all too common for kids to feel like they are alone with their problems. Whether you're seeking information for family, friends, or yourself, these books help explain the challenges faced by people with mental disorders.
Author : Joseph Keon
Publisher : Hatherleigh Press
ISBN 13 : 157826944X
Total Pages : 334 pages
Book Rating : 4.5/5 (782 download)
Download or read book The Alzheimer's Revolution written by Joseph Keon and published by Hatherleigh Press. This book was released on 2022-09-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Alzheimer’s Revolution is the all-in-one guidebook for taking control of your risk factors and reclaiming your overall health. Based on cutting-edge research and the most up-to-date studies, Joseph Keon identifies the risk factors that anyone can control and shatters the myth that Alzheimer’s is caused just by genes. The Alzheimer’s Revolution also provides proven strategies to improve cognition and slow progression in those who have already been diagnosed. Everyone is at risk of developing Alzheimer’s disease, and everyone can take steps to prevent it. The Alzheimer’s Revolution is a complete overhaul of how we understand the risk factors of Alzheimer’s disease, challenging every aspect of current thinking on prevention and treatment. It challenges the misguided and disempowering belief that Alzheimer’s disease cannot be prevented or slowed. The book reveals that over half the Alzheimer’s cases today could be prevented by addressing 7 key lifestyle factors that are within everyone’s ability to control. The Alzheimer's Revolution offers a scientific and evidence-based lifestyle program designed to build cognitive resilience that can dramatically reduce the risk of this devastating condition. Alzheimer’s disease is the number-one public health crisis of our time. It’s time to turn our attention and resources toward prevention.
Author : Michael S. Wolfe
Publisher : Academic Press
ISBN 13 : 0128021640
Total Pages : 678 pages
Book Rating : 4.1/5 (28 download)
Download or read book Developing Therapeutics for Alzheimer's Disease written by Michael S. Wolfe and published by Academic Press. This book was released on 2016-05-27 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing Therapeutics for Alzheimer's Disease: Progress and Challenges provides a thorough overview of the latest advances toward the development of therapeutics for Alzheimer’s disease, along with the major hurdles that still must be overcome and potential solutions to these problems. Despite the lack of progress toward developing therapeutics that can slow or stop the progression of this disease, important discoveries have been made and many promising approaches are advancing in preclinical studies and clinical trials. This book outlines the special challenges related to specific targets and approaches, while presenting a realistic, comprehensive and balanced view of drug discovery and development in this area. Written by international leaders in the field, the book assesses prospects for the emergence of effective agents and allows readers to better understand the challenges, failures, and future potential for research in Alzheimer’s disease. This book is a valuable resource to academic scientists carrying out translational research in Alzheimer’s disease, industrial scientists engaged in Alzheimer's drug discovery, executives in biopharmaceutical companies making strategic decisions regarding the direction of internal research and potential outside partnerships, and graduate-level students pursuing courses on Alzheimer's therapeutics. Provides a realistic but promising assessment of the potential of various therapeutic approaches to Alzheimer’s disease Focuses primarily on neuroprotective agents and cognitive enhancers, as well as approaches to targeting the amyloid B-peptide, tau and Apolipoprotein E Discusses alternative approaches, preclinical and clinical development issues, related biomarkers and diagnostics, and prevention and nonpharmacological approaches
Author : Jack A. Klapper
Publisher : Bookbaby
ISBN 13 : 9781543970449
Total Pages : 74 pages
Book Rating : 4.9/5 (74 download)
Download or read book Alzheimer's Disease written by Jack A. Klapper and published by Bookbaby. This book was released on 2019-06-24 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives Alzheimer's Disease patients and their families up to date information about the current understanding of the disease and how to live with it's challenges.
Author : Stephen G. Post
Publisher : JHU Press
ISBN 13 : 0801870151
Total Pages : 176 pages
Book Rating : 4.8/5 (18 download)
Download or read book The Moral Challenge of Alzheimer Disease written by Stephen G. Post and published by JHU Press. This book was released on 2002-11-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Society today, writes Stephen Post, is "hypercognitive": it places inordinate emphasis on people's powers of rational thinking and memory. Thus, Alzheimer disease and other dementias, which over an extended period incrementally rob patients of exactly those functions, raise many dilemmas. How are we to view—and value—persons deprived of what some consider the most important human capacities? In the second edition of The Moral Challenge of Alzheimer Disease, Post updates his highly praised account of the major ethical issues relating to dementia care. With chapters organized to follow the progression from mild to severe and then terminal stages of dementia, Post discusses topics including the experience of dementia, family caregiving, genetic testing for Alzheimer disease, quality of life, and assisted suicide and euthanasia. New to this edition are sections dealing with end-of-life issues (especially artificial nutrition and hydration), the emerging cognitive-enhancing drugs, distributive justice, spirituality, and hospice, as well as a critique of rationalistic definitions of personhood. The last chapter is a new summary of practical solutions useful to family members and professionals.
Author : Stephen Garrard Post
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.:/5 (12 download)
Download or read book The Moral Challenge of Alzheimer Disease written by Stephen Garrard Post and published by . This book was released on 2000 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Serge Gauthier
Publisher : CRC Press
ISBN 13 : 9781853178375
Total Pages : 400 pages
Book Rating : 4.1/5 (783 download)
Download or read book Alzheimer'S Disease 2/E Slide written by Serge Gauthier and published by CRC Press. This book was released on 1999-03-29 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this successful textbook has been completely updated throughout and includes new chapters on electrophysiological tests, biological markers, global staging measures, and management of neuropsychiatric symptoms. There has been steady progress in our understanding of the natural history, prognostic factors and treatments for Alzheimer's disease since the previous edition of this textbook was published in 1999. The chapters deal with the full spectrum of populations at risk, persons in prodromal stages, and patients from mild to severe and even terminal stages. The contributors are opinion leaders from North America and Europe, which gives the book an internationally balanced outlook. This new edition will be essential reading for a wide range of clinical neuroscientists who manage patients with this challenging disease.
Author : Michael S. Wolfe
Publisher : Springer
ISBN 13 : 9783319866291
Total Pages : 202 pages
Book Rating : 4.8/5 (662 download)
Download or read book Alzheimer’s Disease II written by Michael S. Wolfe and published by Springer. This book was released on 2018-07-29 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors
Author : Hilary W. Poole
Publisher : Mason Crest Publishers
ISBN 13 : 9781422233658
Total Pages : 0 pages
Book Rating : 4.2/5 (336 download)
Download or read book Alzheimer's Disease written by Hilary W. Poole and published by Mason Crest Publishers. This book was released on 2015-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are all forgetful sometimes. As people age, they can become more forgetful still. But when remembering information becomes a daily struggle, a person might be suffering from a condition called Alzheimer's disease. Alzheimer's has been called "the thief," because it steals away the person you loved. Knowing someone with this disease can be hard, but there are ways to encourage your loved ones and help them live happily. The lives of millions of kids are affected by mental illness. And yet it's all too common for kids to feel like they are alone with their problems. Whether you're seeking information for family, friends, or yourself, these books help explain the challenges faced by people with mental disorders. Each title in this series contains color photos and back matter including: an index, further reading lists for books and internet resources, and a series glossary. Mason Crest's editorial team has placed Key Icons to Look for throughout the books in this series in an effort to encourage library readers to build knowledge, gain awareness, explore possibilities and expand their viewpoints through our content rich non-fiction books. Key Icons are as follows: Words to Understand are shown at the front of each chapter with definitions. These words are then used in the prose throughout that chapter, and are emboldened, so that the reader is able to reference back to the definitions- building their vocabulary and enhancing their reading comprehension. Sidebars are highlighted graphics with content rich material within that allows readers to build knowledge and broaden their perspectives by weaving together additional information to provide realistic and holistic perspectives. Text Dependent Questions are placed at the end of each chapter. They challenge the reader's comprehension of the chapter they have just read, while sending the reader back to the text for more careful attention to the evidence presented there. Research Projects are provided at the end of each chapter as well and provide readers with suggestions for projects that encourage deeper research and analysis. A Series Glossary is included in the back matter contains terminology used throughout the series. Words found here broaden the reader's knowledge and understanding of terms used in this field.
Author : Khalid Iqbal
Publisher : John Wiley & Sons
ISBN 13 : 0470851740
Total Pages : 888 pages
Book Rating : 4.4/5 (78 download)
Download or read book Alzheimer's Disease written by Khalid Iqbal and published by John Wiley & Sons. This book was released on 2003-01-24 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Author : Jennifer R. Stelter
Publisher : JHU Press
ISBN 13 : 1421441071
Total Pages : 193 pages
Book Rating : 4.4/5 (214 download)
Download or read book The Busy Caregiver's Guide to Advanced Alzheimer Disease written by Jennifer R. Stelter and published by JHU Press. This book was released on 2021-10-19 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Dementia Connection Model is a recipe to connect families in a way that produces positive interactions and preserves their loved one's level of functioning for as long as possible. The model brings together three concepts in dementia care of what is happening to the person with Alzheimer disease and, more importantly, why these things are happening as the person's condition progresses and how to intervene successfully"--
