Radiopharmaceutical Chemistry

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Author :
Publisher : Springer
ISBN 13 : 3319989472
Total Pages : 648 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Radiopharmaceutical Chemistry by : Jason S. Lewis

Download or read book Radiopharmaceutical Chemistry written by Jason S. Lewis and published by Springer. This book was released on 2019-04-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Technetium-99m Pharmaceuticals

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Medical Isotope Production Without Highly Enriched Uranium

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Publisher : National Academies Press
ISBN 13 : 0309130395
Total Pages : 220 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Isotope Production Without Highly Enriched Uranium by : National Research Council

Download or read book Medical Isotope Production Without Highly Enriched Uranium written by National Research Council and published by National Academies Press. This book was released on 2009-06-27 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

Technetium and Rhenium

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Publisher : Springer
ISBN 13 : 9783540594697
Total Pages : 301 pages
Book Rating : 4.5/5 (946 download)

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Book Synopsis Technetium and Rhenium by : Kenji Yoshihara

Download or read book Technetium and Rhenium written by Kenji Yoshihara and published by Springer. This book was released on 1995-11-15 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Radiopharmaceuticals

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119500540
Total Pages : 768 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Handbook of Radiopharmaceuticals by : Michael R. Kilbourn

Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Technetium in Chemistry and Nuclear Medicine 2

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Author :
Publisher : Cortina (Verona)
ISBN 13 :
Total Pages : 396 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Technetium in Chemistry and Nuclear Medicine 2 by : Marino Nicolini

Download or read book Technetium in Chemistry and Nuclear Medicine 2 written by Marino Nicolini and published by Cortina (Verona). This book was released on 1986 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bone and Soft Tissue Pathology

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Publisher : Elsevier Health Sciences
ISBN 13 : 0443066884
Total Pages : 477 pages
Book Rating : 4.4/5 (43 download)

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Book Synopsis Bone and Soft Tissue Pathology by : Andrew L. Folpe, MD

Download or read book Bone and Soft Tissue Pathology written by Andrew L. Folpe, MD and published by Elsevier Health Sciences. This book was released on 2009-08-04 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today's most essential bone and soft tissue pathology know-how into a compact, high-yield format! The book's pragmatic, well-organized approach-complemented by abundant full-color, high-quality illustrations and at-a-glance tables-makes it easy to access the information you need to quickly and accurately identify pathology specimens. Best of all, Expert Consult functionality provides online access to the full text of the book, downloadable illustrations for your personal use, and more. The result is a practical, affordable reference for study and review as well as for everyday clinical practice. Includes access to the complete contents online, fully searchable, downloadable illustrations for your personal use, and more, allowing you to consult the text a quick, convenient manner. Reviews normal histology before examining abnormal findings, enabling you to conveniently compare their characteristics in one place at one time. Covers both neoplastic and non-neoplastic conditions of bone and soft tissue to equip you to meet a wide range of diagnostic challenges. Uses a consistent, user-friendly format to explore each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations...making it easy to locate specific information on a particular entity. Features abundant boxes and tables throughout that enhance the presentation and accessibility of the material. Offers nearly 1,000 full-color, high-quality illustrations that demonstrate the key features of a wide variety of pathologic lesions to facilitate greater accuracy in identification of specimens. The Foundations in Diagnostic Pathology Series answers the call for fresh, affordable, and easy-to-use guidance. Each region-specific volume provides all of the most essential information on the pathologic entities encountered in practice. Series Editor: John R. Goldblum, MD, FACP, FASCP, FACG Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Handbook of Nuclear Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 144190719X
Total Pages : 3762 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Handbook of Nuclear Chemistry by : Attila Vértes

Download or read book Handbook of Nuclear Chemistry written by Attila Vértes and published by Springer Science & Business Media. This book was released on 2010-12-10 with total page 3762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and extended 6 volume handbook set is the most comprehensive and voluminous reference work of its kind in the field of nuclear chemistry. The Handbook set covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of scores of world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Europe, USA, and Asia. The Handbook set is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook set also provides further reading via the rich selection of references.

Technetium-99m Radiopharmaceuticals

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Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Technetium-99m Radiopharmaceuticals by : IAEA.

Download or read book Technetium-99m Radiopharmaceuticals written by IAEA. and published by . This book was released on 2010 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technetium-99m radiopharmaceuticals will continue to have a significant impact in several areas of nuclear medicine. This publication is intended to provide a broad overview of the current status of technetium-99m radiopharmaceuticals. It includes chapters on the most advanced chemical techniques for labelling biomolecules and synthesizing suitable multifunctional ligands that will help in the development of specific radiotracers. Of special interest for the reader are details of recent research to develop technetium-99m tracers for monitoring different biological processes enabling the develo.

Fundamentals of Nuclear Pharmacy

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Publisher : Springer
ISBN 13 : 3319575805
Total Pages : 430 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Joint Replacement Technology

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Publisher : Woodhead Publishing
ISBN 13 : 0128210834
Total Pages : 726 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Joint Replacement Technology by : Peter A. Revell

Download or read book Joint Replacement Technology written by Peter A. Revell and published by Woodhead Publishing. This book was released on 2021-07-28 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons.This edition covers a range of updated and new content, ranging from chapters on materials analysis and selection, to methodologies and techniques used for joint replacement and clinical challenges of replacing specific joints. Key topics include tribological considerations and experiments; challenges in joint bearing surfaces; cementless fixation techniques; healing responses to implants. Clinical challenges and perspectives are covered with the aid of case studies.Thanks to its widespread collaboration and international contributors, Joint Replacement Technology, Third Edition is useful for materials scientists and engineers in both academia and the biomedical industry. Chemists, clinicians, and other researchers in this area will also find this text invaluable. - This third edition provides an updated comprehensive review of recent developments in joint replacement technology - Reviews a range of specific joints, biological and mechanical issues and fixation techniques - Includes revised and new content, such as sections on regulatory affairs, AI techniques and 3D printing

Farr's Physics for Medical Imaging

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Publisher : Elsevier Health Sciences
ISBN 13 : 0702028444
Total Pages : 216 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Farr's Physics for Medical Imaging by : Penelope J. Allisy-Roberts

Download or read book Farr's Physics for Medical Imaging written by Penelope J. Allisy-Roberts and published by Elsevier Health Sciences. This book was released on 2007-11-14 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. The new edition has been fully updated to reflect the latest advances in technology and legislation and the needs of today's radiology trainees. Invaluable reading, particularly for those sitting the primary and final examinations of the Royal College of Radiology, UK, the book will also be of value to radiographers and personnel interested in medical imaging. The concise text is also accompanied by clear line drawings and sample images to illustrate the principles discussed. Closely matches needs of FRCR examination candidates. Updated to reflect changes to FRCR examination. More medically orientated. Covers new legislation concerning radiological safety etc. 'Must-know' summaries at end of each chapter. Completely new design.

Chelation Therapy in the Treatment of Metal Intoxication

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Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chelation Therapy in the Treatment of Metal Intoxication by : Jan Aaseth

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Nuclear Medicine and Molecular Imaging: The Requisites E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323550746
Total Pages : 522 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Nuclear Medicine and Molecular Imaging: The Requisites E-Book by : Janis P. O'Malley

Download or read book Nuclear Medicine and Molecular Imaging: The Requisites E-Book written by Janis P. O'Malley and published by Elsevier Health Sciences. This book was released on 2020-05-20 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its 5th Edition, this outstanding volume in the popular Requisites series thoroughly covers the fast-changing field of nuclear medicine and molecular imaging. Ideal for residency, clinical rotations, and board review, this compact and authoritative volume by Drs. Janis O'Malley and Harvey Ziessman covers the conceptual, factual, and interpretive information you need to know for success on exams and in clinical practice. NEW to this edition: - More content on molecular imaging and the latest advances in clinical applications, including positron emission tomography (PET), SPECT/CT, PET/CT, and PET/MRI hybrid imaging. - Inclusion of newly approved tracers such as Ga68 DOTA, F-18 amyloid, and F-18 PSMA. - Expanded and integrated content on physics and non-interpretive aspects, including regulatory issues, radiation safety, and quality control. - Up-to-date applications of nuclear medicine in the endocrine, skeletal, hepatobiliary, genitourinary, pulmonary, gastrointestinal, central nervous, and cardiac systems, as well as PET applications for oncology. In the outstanding Requisites tradition, the 5th Edition also: - Summarizes key information with numerous outlines, tables, pearls, pitfalls, and frequently asked questions. - Focuses on essentials to pass the certifying board exam and ensure accurate diagnoses in clinical practice. - Helps you clearly visualize the findings you're likely to see in practice and on exams with nearly 200 full-color images.

Morrey's The Elbow and Its Disorders E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323497284
Total Pages : 1171 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Morrey's The Elbow and Its Disorders E-Book by : Bernard F. Morrey

Download or read book Morrey's The Elbow and Its Disorders E-Book written by Bernard F. Morrey and published by Elsevier Health Sciences. This book was released on 2017-05-05 with total page 1171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised to include the most up-to-date surgical techniques and their outcomes, Morrey's The Elbow and Its Disorders, 5th Edition, is an essential reference for today's orthopaedic surgeons, appealing both to those in general practice and those with a subspecialty interest in elbow surgery. This edition by Drs. Bernard Morrey, Mark Morrey, and Joaquin Sanchez-Sotelo, provides a practical focus on technique – both in the text and on dozens of high-quality instructional videos produced at the Mayo Clinic. Authoritative guidance from leading experts enables you to provide optimal care to your patients – even those with the most challenging elbow problems. - Covers all major areas of elbow surgery, including arthroscopy, trauma, sports, pediatrics, arthroplasty, and salvage procedures. - Supplements the text with full-color-photos, illustrations, and diagrams for a more instructive and visually appealing approach. - Provides expanded coverage of key topics in trauma, soft tissue procedures, joint replacement techniques, and innovative techniques for addressing cartilage lesions and restoring joint motion. - Includes over 2 hours of exam and procedural videos – such as arthroscopic procedures, fracture fixation, arthroplasty, and other reconstructive techniques – performed by the experts online for step-by-step guidance. - Features a new section on arthroscopic surgical procedures, now with expanded indications and evolving techniques. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Nuclear Medicine Physics

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Publisher :
ISBN 13 : 9789201438102
Total Pages : 0 pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Nuclear Medicine Physics by : Dale L. Bailey

Download or read book Nuclear Medicine Physics written by Dale L. Bailey and published by . This book was released on 2015-03-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides the basis for the education of medical physicists initiating their university studies in the field of nuclear medicine. The handbook includes 20 chapters and covers topics relevant to nuclear medicine physics, including basic physics for nuclear medicine, radionuclide production, imaging and non-imaging detectors, quantitative nuclear medicine, internal dosimetry in clinical practice and radionuclide therapy. It provides, in the form of a syllabus, a comprehensive overview of the basic medical physics knowledge required for the practice of medical physics in modern nuclear medicine.