Targeted Cancer Therapy In Biomedical Engineering

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Targeted Cancer Therapy in Biomedical Engineering

Author : Rishabha Malviya
Publisher : Springer Nature
ISBN 13 : 9811997861
Total Pages : 949 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Targeted Cancer Therapy in Biomedical Engineering by : Rishabha Malviya

Download or read book Targeted Cancer Therapy in Biomedical Engineering written by Rishabha Malviya and published by Springer Nature. This book was released on 2023-04-11 with total page 949 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs. Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes. This book discusses the advancements and innovations in the field of BME that improve the diagnosis and treatment of cancer. This book is focused on bioengineering approaches to improve targeted delivery for cancer therapeutics, which include particles, targeting moieties, and stimuli-responsive drug release mechanisms. This book is a useful resource for students, researchers, and professionals in BME and medicine.

Bio-Engineering Approaches to Cancer Diagnosis and Treatment

Author : Azadeh Shahidian
Publisher : Academic Press
ISBN 13 : 0128178108
Total Pages : 276 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Bio-Engineering Approaches to Cancer Diagnosis and Treatment by : Azadeh Shahidian

Download or read book Bio-Engineering Approaches to Cancer Diagnosis and Treatment written by Azadeh Shahidian and published by Academic Press. This book was released on 2020-05-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer

Bioengineering Innovative Solutions for Cancer

Author : Sylvain Ladame
Publisher : Academic Press
ISBN 13 : 0128138874
Total Pages : 396 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Bioengineering Innovative Solutions for Cancer by : Sylvain Ladame

Download or read book Bioengineering Innovative Solutions for Cancer written by Sylvain Ladame and published by Academic Press. This book was released on 2019-11-27 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineering Innovative Solutions for Cancer bridges the gap between bioengineering and cancer biology. It focuses on a ‘bottom up’ understanding of the links between molecules, cells, tissues, organs, organisms, and health and functions—all within a bioengineering context. Chapters cover the main methods, technologies and devices that could help diagnose cancer sooner (e.g., ultrasensitive imaging and sensing technologies) and helpful treatments (e.g., new, more targeted therapies). The book takes an interdisciplinary approach that is ideal for those who need the latest information on design techniques and devices that help treat cancer using new, more targeted therapies. By covering the many different ways engineers can deliver innovative solutions to tackle cancer, this book is a valuable read for researchers who have an ambition to make an impact on people’s life in either an academic or industrial setting. Connects bioengineering and cancer biology, providing information on sensors, imaging, therapies and in-vitro models Presents the most comprehensive coverage in the field of cancer engineering to date Provides an academic introduction to (molecular) bioengineering for students, regardless of scientific background (math's, physics, chemistry, biology) Highlights the unmet medical needs for bioengineers and the main technological breakthroughs to cancer biologists

Targeted Cancer Immune Therapy

Author : Joseph Lustgarten
Publisher : Springer Science & Business Media
ISBN 13 : 1441901701
Total Pages : 343 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Targeted Cancer Immune Therapy by : Joseph Lustgarten

Download or read book Targeted Cancer Immune Therapy written by Joseph Lustgarten and published by Springer Science & Business Media. This book was released on 2009-10-09 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stimulation of the immune system’s ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.

Bioengineering and Cancer Stem Cell Concept

Author : Mirjana Pavlovic
Publisher : Springer
ISBN 13 : 331925670X
Total Pages : 144 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Bioengineering and Cancer Stem Cell Concept by : Mirjana Pavlovic

Download or read book Bioengineering and Cancer Stem Cell Concept written by Mirjana Pavlovic and published by Springer. This book was released on 2015-12-22 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the role of cancer stem cells in the diagnosis, treatment, and cure of cancers. This book also tackles novel methodology for cancer stem cell marker identification, cancer stem cell respiration and metabolism, genetic and epigenetic mechanisms including DNA methylation, and mi-RNA assemble. It also emphasizes the role of Bioinformatics techniques, which provide a novel methodology for modeling cancer outcomes. The authors investigate the difference between cancer stem cells and normal stem cells, along with the concept of targeted cancer stem cell therapy. Although the theoretical explanations of cancer stem cell involvement in leukemia and solid cancers are controversial, there is now little doubt that cancer stem cells exist within otherwise heterogeneous cancer cell population. The brief examines the two leading theories, hierarchical and the stochastic/cancer stem cell model. Researchers, professors and advanced-level students focused on bioengineering and computer science will find this book to be a valuable resource. It is a very good source of critical references for understanding of this problem, and a useful tool for professionals in related fields.

Targeted Cancer Imaging

Author : Mehdi Azizi
Publisher : Academic Press
ISBN 13 : 012824514X
Total Pages : 218 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Targeted Cancer Imaging by : Mehdi Azizi

Download or read book Targeted Cancer Imaging written by Mehdi Azizi and published by Academic Press. This book was released on 2021-11-24 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering. Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models. Gives understanding of cancer biology that is appropriate for students and researchers in engineering and nanotechnology Demonstrates cancer targeting strategies of multifunctional nanotechnology-based imaging probes Shows how to design, synthesize and apply cancer imaging nanostructures

Precision Medicine in Cancer Therapy

Author : Daniel D. Von Hoff
Publisher : Springer
ISBN 13 : 3030163911
Total Pages : 283 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Precision Medicine in Cancer Therapy by : Daniel D. Von Hoff

Download or read book Precision Medicine in Cancer Therapy written by Daniel D. Von Hoff and published by Springer. This book was released on 2019-06-17 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Targeted Therapy in Translational Cancer Research

Author : Apostolia-Maria Tsimberidou
Publisher : John Wiley & Sons
ISBN 13 : 1118468686
Total Pages : 320 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Targeted Therapy in Translational Cancer Research by : Apostolia-Maria Tsimberidou

Download or read book Targeted Therapy in Translational Cancer Research written by Apostolia-Maria Tsimberidou and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Author : Anubhab Mukherjee
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1636391052
Total Pages : 100 pages
Book Rating : 4.6/5 (363 download)

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Book Synopsis Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy by : Anubhab Mukherjee

Download or read book Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy written by Anubhab Mukherjee and published by Morgan & Claypool Publishers. This book was released on 2021-04-06 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators, and industrialists.

Bio-Nanomedicine for Cancer Therapy

Author : Flavia Fontana
Publisher : Springer Nature
ISBN 13 : 3030581748
Total Pages : 358 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Bio-Nanomedicine for Cancer Therapy by : Flavia Fontana

Download or read book Bio-Nanomedicine for Cancer Therapy written by Flavia Fontana and published by Springer Nature. This book was released on 2021-02-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Biomaterials for Cancer Therapeutics

Author : Kinam Park
Publisher : Woodhead Publishing
ISBN 13 : 0081029845
Total Pages : 783 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Biomaterials for Cancer Therapeutics by : Kinam Park

Download or read book Biomaterials for Cancer Therapeutics written by Kinam Park and published by Woodhead Publishing. This book was released on 2020-03-05 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Covers synthetic vaccines, proteins and polymers for cancer therapeutics

Cancer Nanotechnology

Author : Stephen R. Grobmyer
Publisher : Humana Press
ISBN 13 : 9781607616139
Total Pages : 366 pages
Book Rating : 4.6/5 (161 download)

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Book Synopsis Cancer Nanotechnology by : Stephen R. Grobmyer

Download or read book Cancer Nanotechnology written by Stephen R. Grobmyer and published by Humana Press. This book was released on 2011-08-25 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechnology: Methods and Protocols, an international panel of experts provide the most recent, cutting-edge, "how-to" approaches developed and employed by researchers in a variety of disciplines to identify cancer specific biomarkers, construct suitable multifunctional targeted nanostructure platforms, along with enhanced imaging and therapeutic applications. Covering such topics as multifunctional and multimodal nanoparticles, nanoparticle mediated cancer theranostics, molecular targets for cancer nanotechnology, and nanoparticles for non-invasive image-guided cancer therapy, the volume addresses the key challenges of the field today, specifically targeted and localized delivery of the drugs. As a volume in the highly successful Methods in Molecular BiologyTM series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Nanotechnology: Methods and Protocols integrates cancer biology, clinical oncology, molecular cancer imaging, materials science and chemical engineering, biomedical engineering, toxicology, computer science, electrical engineering, chemistry, physics, and mathematics in order to achieve the vital goals of nanotechnology-mediated early cancer detection and more efficacious and less toxic therapies for these devastating diseases.

Biomaterials for Cancer Therapeutics

Author : Kinam Park
Publisher : Elsevier
ISBN 13 : 0857096761
Total Pages : 530 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Biomaterials for Cancer Therapeutics by : Kinam Park

Download or read book Biomaterials for Cancer Therapeutics written by Kinam Park and published by Elsevier. This book was released on 2013-11-23 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction. This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics

Advanced Targeted Nanomedicine

Author : Uche Chude-Okonkwo
Publisher : Springer
ISBN 13 : 3030110036
Total Pages : 143 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Advanced Targeted Nanomedicine by : Uche Chude-Okonkwo

Download or read book Advanced Targeted Nanomedicine written by Uche Chude-Okonkwo and published by Springer. This book was released on 2019-01-11 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents medical challenges as communication engineering problems. It offers the reader the interesting perspective of exploring and understanding disease pathology from the point of view of communication engineers. Therefore, diseases and their treatments can be addressed using conventional communication paradigms, approaches, tools and devices; thereby ushering in the interdisciplinary research platform termed advanced targeted nanomedicine. The rudimentary framework for advanced targeted nanomedicine is presented and expatiated across the seven chapters of this book.

Advances in Particle Therapy

Author : Manjit Dosanjh
Publisher : CRC Press
ISBN 13 : 1351662333
Total Pages : 370 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Advances in Particle Therapy by : Manjit Dosanjh

Download or read book Advances in Particle Therapy written by Manjit Dosanjh and published by CRC Press. This book was released on 2018-05-11 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hadron therapy is a groundbreaking new method of treating cancer. Boasting greater precision than other therapies, this therapy is now utilised in many clinical settings and the field is growing. More than 50 medical facilities currently perform (or are planned to perform) this treatment, with this number set to double by 2020. This new text covers the most recent advances in hadron therapy, exploring the physics, technology, biology, diagnosis, clinical applications, and economics behind the therapy. Providing essential and up-to-date information on recent developments in the field, this book will be of interest to current and aspiring specialists from a wide range of backgrounds. Features: Multidisciplinary approach: explores the physics, IT (big data), biology, clinical applications from imaging to treatment, clinical trials, and economics associated with hadron therapy Contains the latest research and developments in this rapidly evolving field, and integrates them into the current global challenges for radiation therapy Edited by recognised leaders in the field, including the co-ordinator of ENLIGHT (the European Network for Light Ion Hadron Therapy), with chapter contributions from international leading experts in the field

Advances in Nanotheranostics II

Author : Zhifei Dai
Publisher : Springer
ISBN 13 : 9811000638
Total Pages : 381 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Advances in Nanotheranostics II by : Zhifei Dai

Download or read book Advances in Nanotheranostics II written by Zhifei Dai and published by Springer. This book was released on 2016-01-11 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Targeted Therapies

Author : Daniel Gioeli
Publisher : Springer Science & Business Media
ISBN 13 : 1607614782
Total Pages : 211 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Targeted Therapies by : Daniel Gioeli

Download or read book Targeted Therapies written by Daniel Gioeli and published by Springer Science & Business Media. This book was released on 2011-06-02 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.