Systems Biology Approaches To Understanding The Cause And Treatment Of Heart Lung Blood And Sleep Disorders

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Systems Biology Approaches to Understanding the Cause and Treatment of Heart, Lung, Blood, and Sleep Disorders

Author : Raimond L Winslow
Publisher : Frontiers E-books
ISBN 13 : 2889192490
Total Pages : 181 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Systems Biology Approaches to Understanding the Cause and Treatment of Heart, Lung, Blood, and Sleep Disorders by : Raimond L Winslow

Download or read book Systems Biology Approaches to Understanding the Cause and Treatment of Heart, Lung, Blood, and Sleep Disorders written by Raimond L Winslow and published by Frontiers E-books. This book was released on 2014-11-21 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of powerful new high- throughput technologies for probing the transcriptome, proteome and metabolome is driving the rapid acquisition of information on the function of molecular systems. The importance of these achievements cannot be understated – they have transformed the nature of both biology and medicine. Despite this dramatic progress, one of the greatest challenges that continues to confront modern biology is to understand how behavior at the level of genome, proteome and metabolome determines physiological function at the level of cell, tissue and organ in both health and disease. Because of the inherent complexity of biological systems, the development, analysis, and validation of integrative computational models based directly on experimental data is necessary to achieve this understanding. This approach, known as systems biology, integrates computational and experimental approaches through iterative development of mathematical models and experimental validation and testing. The combination of these approaches allows for a mechanistic understanding of the function of complex biological systems in health and their dysfunction in disease. The National Heart, Lung, and Blood Institute (NHLBI) has recognized the importance of the systems biology approach for understanding normal physiology and perturbations associated with heart, lung, blood, and sleep diseases and disorders. In 2006, NHLBI announced the Exploratory Program in Systems Biology, followed in 2010 by the NHLBI Systems Biology Collaborations. The goal of these programs is to support collaborative teams of investigators in using experimental and computational strategies to integrate the component parts of biological networks and pathways into computational models that are based firmly on and validated using experimental data. These validated models are then applied to gain insights into the mechanisms of altered system function in disease, to generate novel hypotheses regarding these mechanisms that can be tested experimentally, and to then use the results of experiments to refine the models. The purpose of this Research Topic is to present the range of innovative, new approaches being developed by investigators working in areas of systems biology that couple experimental and modeling studies to understand the cause and possible treatment of heart, lung, blood and sleep diseases and disorders. This Research Topic will be of great interest to the cardiovascular research community as well as to the general community of systems biologists.

Sleep Disorders and Sleep Deprivation

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101115
Total Pages : 425 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine

Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

A Systems Biology Approach to Blood

Author : Seth Joel Corey
Publisher : Springer
ISBN 13 : 9781493920945
Total Pages : 0 pages
Book Rating : 4.9/5 (29 download)

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Book Synopsis A Systems Biology Approach to Blood by : Seth Joel Corey

Download or read book A Systems Biology Approach to Blood written by Seth Joel Corey and published by Springer. This book was released on 2014-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels. A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.

Washington Information Directory 2021-2022

Author : CQ Press
Publisher : CQ Press
ISBN 13 : 1071825070
Total Pages : 1121 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Washington Information Directory 2021-2022 by : CQ Press

Download or read book Washington Information Directory 2021-2022 written by CQ Press and published by CQ Press. This book was released on 2021-07-15 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Washington Information Directory (WID) is a topically organized reference resource that lists contact information for federal agencies and nongovernmental organizations in the Washington metro area along with a brief paragraph describing what each organization does related to that topic. In addition, The Washington Information Directory pulls together 55 organization charts for federal agencies, congressional resources related to each chapter topic, hotline and contact information for various specific areas of interest (from Food Safety Resources to internships in Washington), and an extensive list of active congressional caucuses and contact details.

NIH Almanac

Author : National Institutes of Health (U.S.). Division of Public Information
Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis NIH Almanac by : National Institutes of Health (U.S.). Division of Public Information

Download or read book NIH Almanac written by National Institutes of Health (U.S.). Division of Public Information and published by . This book was released on 2001 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Washington Information Directory 2020-2021

Author : CQ Press,
Publisher : CQ Press
ISBN 13 : 1544384947
Total Pages : 1126 pages
Book Rating : 4.5/5 (443 download)

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Book Synopsis Washington Information Directory 2020-2021 by : CQ Press,

Download or read book Washington Information Directory 2020-2021 written by CQ Press, and published by CQ Press. This book was released on 2020-06-26 with total page 1126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Washington Information Directory (WID) is a topically organized reference resource that lists contact information for federal agencies and nongovernmental organizations in the Washington metro area along with a brief paragraph describing what each organization does related to that topic. In addition, WID pulls together 55 organization charts for federal agencies, congressional resources related to each chapter topic, hotline and contact information for various specific areas of interest (from Food Safety Resources to internships in Washington), and an extensive list of active congressional caucuses and contact details. WID has two appendices, one with thorough information on congresspersons and committees, and the second with governors and embassies.

Washington Information Directory 2019-2020

Author : CQ Press,
Publisher : CQ Press
ISBN 13 : 1544352840
Total Pages : 1123 pages
Book Rating : 4.5/5 (443 download)

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Book Synopsis Washington Information Directory 2019-2020 by : CQ Press,

Download or read book Washington Information Directory 2019-2020 written by CQ Press, and published by CQ Press. This book was released on 2019-07-03 with total page 1123 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Washington Information Directory is the essential one-stop source for information on U.S. governmental and nongovernmental agencies and organizations. This thoroughly researched guide provides capsule descriptions that help users quickly and easily find the right person at the right organization. The Washington Information Directory offers three easy ways to find information: by name, by organization, and through detailed subject indexes. Although it is a “directory, the volume is topically organized, and within the taxonomic structure the relevant organizations are listed not only with contact information but with a brief paragraph describing what the organization (whether government or nongovernmental) does related to that topic. It is focused on Washington—in order to be listed, an organization must have an office in the Washington metropolitan area. These descriptions are not boilerplate advertising material from the organizations; rather, they are hand-crafted by a talented freelance research team. In addition, the Washington Information Directory pulls together 55 organization charts for federal agencies, congressional resources related to each chapter topic, hotline and contact information for various specific areas of interest (from Food Safety Resources to internships in Washington), and an extensive list of active congressional caucuses and contact details. It has two appendices, one with thorough information on congresspersons and committees, and the second with governors and embassies. With more than 10,000 listing and coverage of the new presidential administration, the 2019–2020 Edition features contact information for the following: • 116th Congress and federal agencies • Nongovernmental organizations • Policy groups, foundations, and institutions • Governors and other state officials • U.S. ambassadors and foreign diplomats • Congressional caucuses

Beyond the Molecular Frontier

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1844 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Report of the Director of the National Heart, Lung, and Blood Institute

Author : National Heart, Lung, and Blood Institute
Publisher :
ISBN 13 :
Total Pages : 438 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Report of the Director of the National Heart, Lung, and Blood Institute by : National Heart, Lung, and Blood Institute

Download or read book Report of the Director of the National Heart, Lung, and Blood Institute written by National Heart, Lung, and Blood Institute and published by . This book was released on 1983 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Theory of Endobiogeny

Author : Kamyar M. Hedayat
Publisher : Academic Press
ISBN 13 : 0128173262
Total Pages : 306 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Theory of Endobiogeny by : Kamyar M. Hedayat

Download or read book The Theory of Endobiogeny written by Kamyar M. Hedayat and published by Academic Press. This book was released on 2019-06-18 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Theory of Endobiogeny Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine offers researchers and clinicians a detailed introduction to the theory of Endobiogeny. The book presents a new approach to medicine that is at once scientific and humanistic, quantitative, and qualitative. The philosophical and experimental basis of a global complex systems approach to physiology is presented along with a mathematical approach to modeling the dynamism of the terrain. The importance of the history and physical examination are renewed as a source of “big data readily available to clinicians for greater insight into the patient’s state. Expansion of the therapeutic compendium is proposed based on a rational, clinical approach correlated to mathematical indicators of the physiologic state. What is proposed in this work is a fundamental shift in scientific thinking with a resulting expansion of the boundaries of clinical medicine for the 21st century and beyond. Extends systems biology from the cellular to the integrative physiologic level Moves the functional medicine approach to a higher level of integration and true global systems thinking Presents mathematical tools and proofs of formulas related to the biology of functions: a biological modeling system based on the theory of endobiogeny. The biology of functions has assisted clinicians in conceptualizing, treating, and objectively monitoring the longitudinal effects of treatment through the evolution of the patient’s unique phenotypic expression of terrain

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2003

Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher :
ISBN 13 :
Total Pages : 1776 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2003 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2003 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2002 with total page 1776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Coronary Primary Prevention Trial

Author :
Publisher :
ISBN 13 :
Total Pages : 2 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Coronary Primary Prevention Trial by :

Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrative Preventive Medicine

Author : Richard H. Carmona
Publisher : Oxford University Press
ISBN 13 : 019024125X
Total Pages : 585 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Integrative Preventive Medicine by : Richard H. Carmona

Download or read book Integrative Preventive Medicine written by Richard H. Carmona and published by Oxford University Press. This book was released on 2017-12-12 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: For most clinicians, the science and evidence for many integrative therapies is largely unknown or considered suspect. Most physicians don't have time to learn integrative approaches and aren't sure what to recommend or which approaches have merit or improved outcomes. Here, clinicians have easy access to the best practices in integrative medicine and expectations for outcomes

Integrative and Functional Medical Nutrition Therapy

Author : Diana Noland
Publisher : Springer Nature
ISBN 13 : 3030307301
Total Pages : 1101 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Integrative and Functional Medical Nutrition Therapy by : Diana Noland

Download or read book Integrative and Functional Medical Nutrition Therapy written by Diana Noland and published by Springer Nature. This book was released on 2020-03-27 with total page 1101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the application of the philosophy and principles of Integrative and Functional Medical Nutrition Therapy (IFMNT) in the practice of medicine, and the key role nutrition plays in restoring and maintaining wellness. The textbook provides an overview of recent reviews and studies of physiological and biochemical contributions to IFMNT and address nutritional influences in human heath overall, including poor nutrition, genomics, environmental toxicant exposures, fractured human interactions, limited physical movement, stress, sleep deprivation, and other lifestyle factors. Ultimately, this textbook serves to help practitioners, healthcare systems, and policy makers better understand this different and novel approach to complex chronic disorders. It provides the reader with real world examples of applications of the underlying principles and practices of integrative/functional nutrition therapies and presents the most up-to-date intervention strategies and clinical tools to help the reader keep abreast of developments in this emerging specialty field. Many chapters include comprehensive coverage of the topic and clinical applications with supplementary learning features such as case studies, take-home messages, patient and practitioner handouts, algorithms, and suggested readings. Integrative and Functional Medical Nutrition Therapy: Principles and Practices will serve as an invaluable guide for healthcare professionals in their clinical application of nutrition, lifestyle assessment, and intervention for each unique, individual patient.

The Practical Guide

Author :
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Practical Guide by :

Download or read book The Practical Guide written by and published by . This book was released on 2002 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1997

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1997 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1997 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1996 with total page 2182 pages. Available in PDF, EPUB and Kindle. Book excerpt: