Systems Analysis of Possible Mechanisms of Mammalian Aging

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Systems Analysis of Possible Mechanisms of Mammalian Aging by : W. Donner Denckla

Download or read book Systems Analysis of Possible Mechanisms of Mammalian Aging written by W. Donner Denckla and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Biology of Senescence

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Publisher : CreateSpace
ISBN 13 : 9781456392420
Total Pages : 274 pages
Book Rating : 4.3/5 (924 download)

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Book Synopsis The Biology of Senescence by : Alex Comfort

Download or read book The Biology of Senescence written by Alex Comfort and published by CreateSpace. This book was released on 2010-11-25 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Senescence

Aging and Recovery of Function in the Central Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 1461327059
Total Pages : 228 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Aging and Recovery of Function in the Central Nervous System by : Stephen W. Scheff

Download or read book Aging and Recovery of Function in the Central Nervous System written by Stephen W. Scheff and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian central nervous system is a remarkable structure which has attracted many new investigators, as evidenced by the dramatic increase in scientific publications dealing with neurobiology. Every day basic scientists conduct new and exciting experiments, resulting in remarkable discoveries des tined to help mankind. Unfortunately many of these new findings are slow to be accepted by the clinical world. This is especially true in the area of brain trauma, where the present prognosis is usually very poor. We have known for quite some time that the mammalian central nervous system is capable of compensating for severe damage in many different ways, and under some circumstances behav ioral compensation can be observed. However, much is still to be learned about the various factors and events that lead to functional recovery and those condi tions that do not. It is this challenge that originally excited a number of the contributors to this volume to explore the subject of recovery from brain damage. One factor in particular that is known to change the prognosis of recovery is the age of the organism at the time of the damage. This book is an attempt to explore this important variable. Most of the literature concerning aging deals with widespread degenerative changes and paints a grim picture for the aging central nervous system in terms of recovery of function following trauma.

The Thymus in Health and Senescence

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Publisher : CRC Press
ISBN 13 : 1000694658
Total Pages : 352 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis The Thymus in Health and Senescence by : Nathan F. Cardarelli

Download or read book The Thymus in Health and Senescence written by Nathan F. Cardarelli and published by CRC Press. This book was released on 2019-07-17 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1989: This text was written to provide a relatively broad comprehensive study of the thymus in health and disease, including relationships to the endocrine system, immue system, and again.

Animals, Aging, and the Aged

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Publisher : U of Minnesota Press
ISBN 13 : 0816657165
Total Pages : 247 pages
Book Rating : 4.8/5 (166 download)

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Book Synopsis Animals, Aging, and the Aged by : Leo K. Bustad

Download or read book Animals, Aging, and the Aged written by Leo K. Bustad and published by U of Minnesota Press. This book was released on 1981-02-20 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals, Aging, and the Aged was first published in 1981. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. This volume explores the significant contributions of animals to our understanding of aging, to improving geriatric medicine, and to providing companionship and assistance to the elderly. Leo L. Bustad discusses what can be learned from animal life-span studies about the process of aging, including the problems of cardiovascular disease, cancer, osteoporosis, and age-related mental conditions. The results of these studies suggest that changes in life-style—especially the diet—may modify the effects of chronic degenerative diseases. Other studies show that caring for a pet can contribute greatly to the health and well being of the elderly. Bustad surveys experiments using animals in therapy and he presents, for the first time, evaluative instruments for choosing the appropriate pet. Companion animals allow many elderly people to maintain their independence. Animals are also helpful as aids for those with visual, hearing, and physical impairments. An appendix lists agencies that train dogs as aids to the physically impaired. Animals, Aging, and the Aged is a thoughtful discussion of the physical, psychological, and social problems faced by the elderly, with emphasis on the ways that animals have contributed to the solution of some of those problems. As such, it will be useful for those involved in geriatric medicine and social work and in veterinary medicine and research. This book is volume 5 in the series Wesley W. Spink Lectures in Comparative Medicine.

Immunological Aspects of Neoplasia — The Role of the Thymus

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Publisher : Springer Science & Business Media
ISBN 13 : 1402021852
Total Pages : 212 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Immunological Aspects of Neoplasia — The Role of the Thymus by : Bela Bodey

Download or read book Immunological Aspects of Neoplasia — The Role of the Thymus written by Bela Bodey and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our work began where the greatest classical morphologists left off; their best work was the start of ours. As our work progressed, the rigidity of basic, previous embryological principles was broken down as scientific knowledge advanced. At the same time, the molecular, biological characterization of the cell surface receptor systems progressed enormously with the invention of NUMEROUS monoclonal antibodies. Thus, thymology became once again very important because the thymus is the first and central organ of the human immunological system. Then, the question of immuno-neuroendocrine regulation arose and has only been partially answered. Our book seeks to explore what has not been explored. The topic of thymic epithelial cells is a unique one and has never been explored in any previous book as it is explored in this one. Only a handful of great thymologists remain in the world today, especially after the great loss the medical community suffered with the passing of Dr. Good, the list includes but is not limited to: Dr. Ritter and Dr. Kendall in England, Dr. Savino in Brazil, Dr. Dardenne in France, Dr. von Gaudecker in Germany, a few others in Belgium and Holland, and it is our hope that Dr. Bodey is among them. Nonetheless, a book on the thymus has not been written in the last five years and a book such as this one has never been. This book is based on a 30-year period of research and includes references from a broad range of sources spanning the globe and all sources, even those that were the beginning of thymic research. The book, thus, is uniquely well rounded, more so that previous works.

Brain Aging

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Publisher : CRC Press
ISBN 13 : 9781420005523
Total Pages : 408 pages
Book Rating : 4.0/5 (55 download)

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Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Epigenetics of Aging

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Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Molecular Mechanisms of Aging

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Publisher : Springer Science & Business Media
ISBN 13 : 3642842240
Total Pages : 327 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Molecular Mechanisms of Aging by : Konrad Beyreuther

Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bibliography of Medical Reviews

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Publisher :
ISBN 13 :
Total Pages : 1802 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bibliography of Medical Reviews by :

Download or read book Bibliography of Medical Reviews written by and published by . This book was released on 1976 with total page 1802 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Geroscience

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Publisher : Springer
ISBN 13 : 3319232460
Total Pages : 637 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Advances in Geroscience by : Felipe Sierra

Download or read book Advances in Geroscience written by Felipe Sierra and published by Springer. This book was released on 2015-11-10 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 904 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1977 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt:

CNS Aging and Its Neuropharmacology

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Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805529808
Total Pages : 232 pages
Book Rating : 4.5/5 (298 download)

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Book Synopsis CNS Aging and Its Neuropharmacology by : William Meier-Ruge

Download or read book CNS Aging and Its Neuropharmacology written by William Meier-Ruge and published by S. Karger AG (Switzerland). This book was released on 1979 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Diseases of Aging

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Publisher :
ISBN 13 :
Total Pages : 568 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Diseases of Aging by : Herman T. Blumenthal

Download or read book Handbook of Diseases of Aging written by Herman T. Blumenthal and published by . This book was released on 1983 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Monthly Bibliography of Medical Reviews

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Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Monthly Bibliography of Medical Reviews by :

Download or read book Monthly Bibliography of Medical Reviews written by and published by . This book was released on 1977 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Frontiers in Aging Research

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Publisher :
ISBN 13 :
Total Pages : 588 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Frontiers in Aging Research by :

Download or read book Frontiers in Aging Research written by and published by . This book was released on 1979 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neural Regulatory Mechanisms During Aging

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Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neural Regulatory Mechanisms During Aging by : Richard C. Adelman

Download or read book Neural Regulatory Mechanisms During Aging written by Richard C. Adelman and published by . This book was released on 1980 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: