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Synthetic Vaccines
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Download or read book Synthetic Vaccines written by and published by Academic Press. This book was released on 2012-12-06 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on synthetic vaccines. Contributions from leading authorities Informs and updates on all the latest developments in the field
Download or read book SYNTHETIC VACCINES written by Ruth Arnon and published by CRC-Press. This book was released on 1987-08-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Peptide Vaccine Models by : Mesut Karahan
Download or read book Synthetic Peptide Vaccine Models written by Mesut Karahan and published by CRC Press. This book was released on 2021-02-28 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy
Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Book Synopsis Recombinant and Synthetic Vaccines by :
Download or read book Recombinant and Synthetic Vaccines written by and published by . This book was released on 1994 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Vaccines by : Cornelius Melief
Download or read book Synthetic Vaccines written by Cornelius Melief and published by Academic Press. This book was released on 2012-04-02 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on synthetic vaccines. Contributions from leading authorities Informs and updates on all the latest developments in the field
Book Synopsis Introduction to Recombinant Vaccines by : Dr. Ramesh C.K.
Download or read book Introduction to Recombinant Vaccines written by Dr. Ramesh C.K. and published by Lulu.com. This book was released on 2017-02-14 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system is a network of cells, tissues, and organs that work together to defend the body against attacks by "foreign" invaders. Invaders are primarily microbes such as bacteria, viruses, parasites and fungi. Because the human body provides an ideal environment for many microbes, they try to break in. It is the immune system's job to keep them out or, failing that, to seek out and destroy them. When the immune system hits the wrong target or is crippled, however, it can unleash seversl diseases, including allergy, arthritis or immune disorders.
Book Synopsis Epitope Discovery and Synthetic Vaccine Design by : Clarisa Beatriz Palatnik-de-Sousa
Download or read book Epitope Discovery and Synthetic Vaccine Design written by Clarisa Beatriz Palatnik-de-Sousa and published by Frontiers Media SA. This book was released on 2018-07-12 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Vaccines from Peptide Libraries by : Leslie Jeanne Matthews
Download or read book Synthetic Vaccines from Peptide Libraries written by Leslie Jeanne Matthews and published by . This book was released on 1998 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional approaches to synthetic vaccine design rely on detailed investigation of a pathogen's antigenic structure to locate and characterize candidate natural epitopes with immunogenic potential "Epitope discovery", a new, alternative strategy for identifying synthetic vaccine components, offers several potential advantages over conventional methods. In this strategy antibodies from the blood of diseased or immunized subjects are used to affinity-select peptides from enormous libraries. The affinity-selected peptides are referred to as "antigenic mimics" since they presumably mimic one of the native epitopes that originally elicited the antibody. Such antigenic mimics can serve as synthetic vaccine components if they are able to induce a protective immune response in naive subjects. Unfortunately, efforts to develop synthetic peptide vaccines--whether by traditional methods or epitope discovery--have been hindered by inability to predict which antigenic mimics will ultimately prevail as "immunogenic mimics", able to elicit antibodies that cross-react with the original pathogen. We used bacteriophage T4 as the model "pathogen" in a systematic epitope discovery project aimed at distinguishing properties of antigenic mimics that correlate with good immunogenic mimicry. Anti-pathogen-antibodies raised in mice were used to affinity-select antigenic mimics from constrained and unconstrained random peptide libraries (RPLs), and from a novel, natural peptide library (NPL) consisting of fragments of actual pathogen proteins. All three types of libraries yielded antigenic mimics which bind strongly and specifically to anti-T4-antibodies. To assess the ability of the peptides to induce antibodies that cross-react with the model pathogen, naive mice were hyperimmunized with 22 representative peptides. A few of the antigenic mimics from RPLs succeeded as immunogenic mimics, in that they induced indirect antibodies that cross-react with the pathogen. However, a more rigorous analysis showed that the overall degree of immunogenic mimicry achieved by these peptides is quite small. In contrast, two of four antigenic mimics from the NPL turned out to be exceptionally good immunogenic mimics by our rigorous analysis. Thus, we propose a modified epitope discovery strategy employing NPLs instead of, or in addition to, RPLs, to maximize the chances of finding the best possible immunogenic mimics to include in synthetic peptide vaccines. This novel approach combines the best aspects of both epitope discovery and traditional natural epitope identification, and could hasten development of synthetic peptide vaccines against important diseases of domesticated animals and humans.
Book Synopsis Immunotherapy and Vaccines by : Stanley J. Cryz
Download or read book Immunotherapy and Vaccines written by Stanley J. Cryz and published by Wiley-VCH. This book was released on 1991 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Revolutionizing Vaccines by : Leonel Bolt
Download or read book Revolutionizing Vaccines written by Leonel Bolt and published by Independently Published. This book was released on 2023-12-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Step into the future of healthcare with "Revolutionizing Vaccines: The Era of Synthetic Immunity," a groundbreaking exploration of the cutting-edge advancements propelling us into a new era of disease prevention and immune response. In this illuminating book, delve into the revolutionary landscape of synthetic immunity, where scientific innovation and technology converge to redefine the way we combat infectious diseases. Author [Your Name], a leading expert in the field, takes you on a captivating journey through the latest breakthroughs in vaccine development, revealing the transformative power of synthetic approaches. Discover how synthetic vaccines are poised to redefine the very essence of immunity, offering unprecedented precision and effectiveness. Explore the convergence of artificial intelligence, genetic engineering, and bioinformatics, unlocking the potential to tailor vaccines to individual genetic profiles. Uncover the promise of personalized immunization strategies, ushering in an era where vaccines are finely tuned to match the unique immune landscapes of diverse populations. "Revolutionizing Vaccines" provides a comprehensive overview of the science behind synthetic immunity, breaking down complex concepts into accessible insights. From mRNA vaccines to innovative delivery systems, witness the evolution of vaccination strategies that promise not only to protect against known diseases but also to anticipate and thwart emerging threats. As society navigates the challenges of infectious diseases, this book serves as a beacon of hope, demonstrating how synthetic immunity holds the key to a safer and healthier world. Engage with thought-provoking discussions on ethical considerations, societal impacts, and the potential for global collaboration in shaping the future of preventive medicine. Whether you're a healthcare professional, a science enthusiast, or a curious reader eager to understand the future of medicine, "Revolutionizing Vaccines: The Era of Synthetic Immunity" is your passport to the forefront of scientific progress. Join the conversation, embrace the possibilities, and prepare for a future where synthetic immunity transforms the landscape of public health. Embrace the future today!
Download or read book mRNA Vaccines written by Dong Yu and published by Springer Nature. This book was released on 2023-01-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
Book Synopsis Novel Strategies in the Design and Production of Vaccines by : Sara Cohen
Download or read book Novel Strategies in the Design and Production of Vaccines written by Sara Cohen and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conference, we present some of the recent strategies for the design and production of novel vaccines. The advent of recombinant DNA technology has stimulated the production of several subunit vaccines. In spite of the obvious advantages to this approach, the limited immuno genicity of many subunit candidates has hindered their development. Strategies to enhance the immunogenicity of subunit vaccines is therefore critical. Several approaches toward this goal, including design of novel adjuvants and delivery systems as well as design of advantageous carriers, are presented here. Among the carriers evaluated here are polypep tides (flagellin, HBV core antigen, J3-galactosidase), attenuated virions (Vaccinia, Sindbis), and nonpathogenic licensed bacteria (Salmonella).
Book Synopsis Anti-Idiotypic Vaccines by : Pierre-Andre Cazenave
Download or read book Anti-Idiotypic Vaccines written by Pierre-Andre Cazenave and published by Springer. This book was released on 1991 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine~hat enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti-idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out. A new breed of vaccines is on the horizon that seeks to control fertility.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309465184 Total Pages :189 pages Book Rating :4.3/5 (94 download)
Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine
Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Book Synopsis Synthetic Peptide Vaccine Models by : Mesut Karahan
Download or read book Synthetic Peptide Vaccine Models written by Mesut Karahan and published by CRC Press. This book was released on 2021-02-28 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy
Book Synopsis Development of Synthetic Vaccines for Human Melanoma by : Vishakha Vora
Download or read book Development of Synthetic Vaccines for Human Melanoma written by Vishakha Vora and published by . This book was released on 2000 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
