Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Synthetic Studies Towards The Spiroketal Portion Of Avermectins full books in PDF, epub, and Kindle. Read online Synthetic Studies Towards The Spiroketal Portion Of Avermectins ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Neil Francis Badham
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (598 download)
Download or read book Synthetic Studies Towards the Spiroketal Portion of Avermectins written by Neil Francis Badham and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rosemary O'Mahony
Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.:/5 (196 download)
Download or read book Studies Toward the Total Synthesis of Spiroketal Containing Natural Products written by Rosemary O'Mahony and published by . This book was released on 1988 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ulhas S. Warrier
Publisher :
ISBN 13 :
Total Pages : 118 pages
Book Rating : 4.:/5 (19 download)
Download or read book Synthesis of a Model of the Spiroketal Portion of Avermectin B written by Ulhas S. Warrier and published by . This book was released on 1987 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avermectin Bia is a member of a class of medicinally important natural products known for its potent antiparasitic activity and interesting structural features. In this thesis, synthesis of a model for the spiroketal portion of the avermectins is presented. Oxidation of (S)-2-methylbutanol, followed by a stereoselective chromium mediated reaction with crotyl bromide, gave (3S,4R15S)-3,5- dimethy1-1-hepten-4-ol as the major isomer. After investigating a variety of protecting groups, the alcohol was masked as a t- butyldimethylsilyl ether and subsequent ozonolytic cleavage of the vinyl group afforded the corresponding aldehyde. Reaction of this aldehyde with carbon tetrabromide and triphenylphosphine resulted in its homologation to a dibromoolefin, which underwent elimination with butyllithium to yield (3S,4R15S)-4-t-butyldimethylsiloxy-3 5-dimethy1-1- heptyne. Selective protection of the primary alcohol of R-( - )-1,3- butanediol as its 214,6-triisopropylbenzenesulfonate, followed by the acetylation of the secondary alcohol, provided (2R)-4-(2,416- triisopropylbenzenesulfonyloxy)-2-acetoxybutane. The latter was converted to the corresponding iodide which, when treated with lithium diisopropylamide, cyclized to (R)-S-caprolactone. Alkylation of the S-lactone with either the dibromoolefin or the alkyne after treatment with butyllithium, followed by reaction with methanol on Amberlite ion exchange resin, gave (2RS16R)-2- [(3S,4R15S)-4-t-butyldimethylsiloxy-3,5-dimethyl-l-heptynyl]-2-methoxy -6-methyltetrahydropyran. Deprotection, and then Lindlar hydrogenation of this compound with an acidic workup led to the formation of the target compound (2R13S16R18R)-318-dimethy1-2f(1S)-1-methylpropy11- 1,7-dioxaspiro[5.5]undec-4-ene.
Author : David Diez Martin
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (99 download)
Download or read book Synthetic studies on CP-61,405 and Avermectin B1a written by David Diez Martin and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Part I: Studies Leading to the Synthesis of Avermectin A1[subscript]a; Part II: An Approach Towards the Synthesis of Echinosporin PDF Online Free](https://books.google.com/books/content/images/frontcover/EWnrXwAACAAJ?fife=w200-h370)
Author : Francine Ellen Wincott
Publisher :
ISBN 13 :
Total Pages : 374 pages
Book Rating : 4.:/5 (72 download)
Download or read book Part I: Studies Leading to the Synthesis of Avermectin A1[subscript]a; Part II: An Approach Towards the Synthesis of Echinosporin written by Francine Ellen Wincott and published by . This book was released on 1989 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : George Walter Griesgraber
Publisher :
ISBN 13 :
Total Pages : 478 pages
Book Rating : 4.:/5 (319 download)
Download or read book Roflamycoin: Synthetic Studies and Stereochemical Assignment written by George Walter Griesgraber and published by . This book was released on 1994 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William C. Campbell
Publisher : Springer Science & Business Media
ISBN 13 : 1461236266
Total Pages : 380 pages
Book Rating : 4.4/5 (612 download)
Download or read book Ivermectin and Abamectin written by William C. Campbell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.
Author :
Publisher :
ISBN 13 :
Total Pages : 498 pages
Book Rating : 4.3/5 (91 download)
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 1997 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theses on any subject submitted by the academic libraries in the UK and Ireland.
Author : Gabor Lukacs
Publisher : Springer Science & Business Media
ISBN 13 : 3642756174
Total Pages : 808 pages
Book Rating : 4.6/5 (427 download)
Download or read book Recent Progress in the Chemical Synthesis of Antibiotics written by Gabor Lukacs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class have also reached an important place in the medical treatment of human cancer. Although, the discovery of most of these agents came from more or less sophisticated screening programs of soil microrganisms, many of the important antibiotics used today in clinical practice are derived from the original biosynthetic products by the application of often novel and generally elaborated chemical synthetic methodologies. In fact the antibiotics have represented (and still represent) for a generation of organic chemists an endless source of molecular structures whose varied assemblage of carbon atom backbones and chemical functions was beyond any possibility of imagination. Perhaps a similar repertoire of chemotypes was formerly offered by the natural products, namely the alkaloids, the terpenes, the vitamins and hormones as well as the pigments of the animal and plant kingdoms, albeit the chemical arrange ments of the antibiotic molecules appeared much more surprising and diverse to the admiring eyes of cultivated organic chemists. The idea of this book, certainly a landmark in the field, came during the Symposium of EUCHEM on Chemical Synthesis of Antibiotics, that was held at Aussois in Savoy, France (May 2-6, 1988), the initiative being taken by Gabor Lukacs to whom Masaji Ohno readily associated as a co-editor.
Author : Wade H. Shafer
Publisher : Springer Science & Business Media
ISBN 13 : 1461573947
Total Pages : 430 pages
Book Rating : 4.4/5 (615 download)
Download or read book Masters Theses in the Pure and Applied Sciences written by Wade H. Shafer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Masters Theses in the Pure and Applied Sciences was first conceived, published, and disseminated by the Center for Information and Numerical Oata Analysis and Synthesis (CINOAS) * at Purdue. University in 1957, starting its coverage of theses with the academic year 1955. Beginning with Volume 13, the printing and dissemination phases of the activity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all con cerned if the printing and distribution of the volumes were handled by an interna tional publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Cor poration of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 33 (thesis year 1988) a total of 13,273 theses titles from 23 Canadian and 1 85 United States universities. We are sure that this broader base for these titles reported will greatly enhance the value of this important annual reference work. While Volume 33 reports theses submitted in 1988, on occasion, certain univer sities do report theses submitted in previous years but not reported at the time.
Author : N. Anand
Publisher : Elsevier
ISBN 13 : 0080527523
Total Pages : 525 pages
Book Rating : 4.0/5 (85 download)
Download or read book Approaches to Design and Synthesis of Antiparasitic Drugs written by N. Anand and published by Elsevier. This book was released on 1997-07-10 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.
Author : British Library. Document Supply Centre
Publisher :
ISBN 13 :
Total Pages : 704 pages
Book Rating : 4.3/5 (91 download)
Download or read book British Reports, Translations and Theses written by British Library. Document Supply Centre and published by . This book was released on 1994 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel E. Levy
Publisher : CRC Press
ISBN 13 : 1420027956
Total Pages : 904 pages
Book Rating : 4.4/5 (2 download)
Download or read book The Organic Chemistry of Sugars written by Daniel E. Levy and published by CRC Press. This book was released on 2005-09-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst
Author : G Pattenden
Publisher : Royal Society of Chemistry
ISBN 13 : 1847556272
Total Pages : 466 pages
Book Rating : 4.8/5 (475 download)
Download or read book General and Synthetic Methods written by G Pattenden and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Author : Adilson Beatriz
Publisher : Bentham Science Publishers
ISBN 13 : 1608059022
Total Pages : 285 pages
Book Rating : 4.6/5 (8 download)
Download or read book Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases written by Adilson Beatriz and published by Bentham Science Publishers. This book was released on 2014-08-04 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization (WHO) has reported 14 diseases that are occurring exclusively in tropical areas. Most of these diseases are infectious and mainly affect poor populations. Some of these diseases include malaria, dengue fever, leishmaniasis and Chagas disease. Therefore, an acute need for increasing the arsenal of drugs is required to fight against these neglected diseases for the guaranteed recovery and relief of many patients. This E-book gathers important scientific research performed by scientists worldwide showing the state of the art of Medicinal Chemistry dedicated to the synthesis of compounds that are potentially bioactive against the causative agents of neglected diseases. The contents of this book include chapters on recent advances in synthetic organic compounds for the prevention of Chagas disease, recent advances in the discovery of small organic molecules for the prevention and treatment of dengue fever, leishmaniasis, leprosy, therapeutic arsenal and drug discovery for lymphatic filariasis, therapeutic agents for the treatment of malaria, schistosomiasis and synthetic organic compounds as potential antitubercular drugs. This book is intended for undergraduate and graduate students in institutes, colleges, universities and academies who want to specialize in the field of organic synthesis and medicinal chemistry.This book will also be a valuable resource of information for researchers in this field.
Author :
Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.3/5 (91 download)
Download or read book Chemtracts written by and published by . This book was released on 1998 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consists of reviews, condensations, and commentaries.
Author : John ApSimon
Publisher : John Wiley & Sons
ISBN 13 : 9780471545071
Total Pages : 726 pages
Book Rating : 4.5/5 (45 download)
Download or read book The Total Synthesis of Natural Products, Volume 8 written by John ApSimon and published by John Wiley & Sons. This book was released on 1992-04-16 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemistry's innovative breadth is especially noteworthy in the area of natural products synthesis. Since the early 1970s, this landmark chemical reference has been documenting the newest and most important of these, in a readily understood format, that clearly traces each of their synthetic routes. Volume Eight, the latest in the series, contains a long-awaited look at the synthesis of tri- and tetracyclic diterpenes, along with the synthesis of naturally occurring quinones. Recent interest in the biologically important polysaccharides has led to a detailed consideration of that compound class. Finally, this new volume contains a look at the strategies and methods specific to natural products containing the spiroketal functional group. The Total Synthesis of Natural Products, Volume Eight, continues the meticulous work of the series, providing chemists with an entirely up-to-date and convenient guide to the critical new syntheses essential to organic chemistry's continuing evolution.
