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Synthetic Metabolic Engineering Of Corynebacterium Glutamicum For Bio Based Production Of 15 Diaminopentane
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Book Synopsis Synthetic Metabolic Engineering of Corynebacterium glutamicum for Bio-based Production of 1,5-Diaminopentane by : Stefanie Kind
Download or read book Synthetic Metabolic Engineering of Corynebacterium glutamicum for Bio-based Production of 1,5-Diaminopentane written by Stefanie Kind and published by Cuvillier Verlag. This book was released on 2012-11-05 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Systems Metabolic Engineering by : Christoph Wittmann
Download or read book Systems Metabolic Engineering written by Christoph Wittmann and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Book Synopsis Metabolic Engineering by : Sang Yup Lee
Download or read book Metabolic Engineering written by Sang Yup Lee and published by John Wiley & Sons. This book was released on 2021-06-02 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.
Book Synopsis Engineering Corynebacterium Glutamicum Chassis for Synthetic Biology, Biomanufacturing, and Bioremediation by : Akihiko Kondo
Download or read book Engineering Corynebacterium Glutamicum Chassis for Synthetic Biology, Biomanufacturing, and Bioremediation written by Akihiko Kondo and published by Frontiers Media SA. This book was released on 2022-07-01 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Industrial Biotechnology by : Christoph Wittmann
Download or read book Industrial Biotechnology written by Christoph Wittmann and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
Book Synopsis Corynebacterium glutamicum by : Nami Tatsumi
Download or read book Corynebacterium glutamicum written by Nami Tatsumi and published by Springer Science & Business Media. This book was released on 2012-08-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
Book Synopsis Systems Metabolic Engineering of Corynebacterium Glutamicum Towards Improved Lysine Production by : Judith Becker
Download or read book Systems Metabolic Engineering of Corynebacterium Glutamicum Towards Improved Lysine Production written by Judith Becker and published by . This book was released on 2010 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis From Waste to Value by : Nele Buschke
Download or read book From Waste to Value written by Nele Buschke and published by Cuvillier Verlag. This book was released on 2013-06-27 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time, 1,5-diaminopentane (polyamide monomer) production from xylose was achieved by a recombinant Corynebacterium glutamicum strain. Via rational metabolic engineering the product yield was increased by 54% and the productivity by 100%. The tailor-made strain finally accumulated 103 g L-1 diaminopentane in a fed-batch fermentation, the highest titer ever obtained on xylose. In a two-step process hemicellulose was used as substrate. The monosaccharides were first obtained by hydrolysis and then further used as substrate for the production of 1,5-diaminopentane. Another resource tested was black liquor, a major industrial waste from pulp and paper manufacturing. It turned out that pre-treatment of the black liquor is necessary to obtain bioavailable sugars for subsequent production. The optimized C. glutamicum strain grew well on the black liquor hydrolysate and efficiently converted the containing carbon into 1,5-diaminopentane. The achieved product yield was about 120 % higher than on pure xylose. In this regard, the present work displays a milestone in industrial strain- and bioprocess engineering of C. glutamicum. Die Herstellung des Polyamidmonomers, 1,5-Diaminopentan, aus Xylose, wurde in dieser Arbeit zum ersten Mal, mit Hilfe eines rekombinanten Corynebacterium glutamicum Stammes realisiert. Durch gezieltes Metabolic Engineering konnte die Ausbeute des Stammes um 54%, die Produktivität um 100 % gesteigert werden. In einer Fed-Batch Fermentation wurde mit diesem maßgeschneiderten Stamm 103 g L-1 Diaminopentane, die höchste jemals erreichte Konzentration auf Xylose, produziert. In einem zweistufigen Prozess wurde anschließend Hemicellulose als Substrat für die Produktion eingesetzt. Die Monosaccharide wurden dabei zunächst in einer enzymatischen Hydrolyse aus der Hemicellulose gewonnen und für die biotechnologischen Produktion von 1,5-Diaminopentan eingesetzt. Als weiterer Rohstoff wurde Schwarzlauge, ein industrieller Abfallstoff aus der Papierindustrie, als Substrat eingesetzt. Es stellte sich heraus, dass eine Vorbehandlung der Schwarzlauge notwendig ist, um die Zucker für die darauf folgende Produktion verfügbar zu machen. Der optimierte C. glutamicum Stamm war in der Lage den Kohlenstoff aus dem Schwarzlauge Hydrolysat zu verstoffwechseln und effizient 1,5-Diaminopentane, mit einer um 120 % gesteigerten Produktausbeute, zu produzieren. Die vorliegende Arbeit repräsentiert daher einen Meilenstein der industriellen Stamm- und Bioprozessentwicklung von Corynebacterium glutamicum.
Book Synopsis Lignin Valorization by : Gregg T. Beckham
Download or read book Lignin Valorization written by Gregg T. Beckham and published by Royal Society of Chemistry. This book was released on 2018-03-29 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Chapters will specifically focus on the production of fuels and chemicals from lignin."--Page [4] of cover.
Book Synopsis Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering by : Volker F. Wendisch
Download or read book Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering written by Volker F. Wendisch and published by Springer Science & Business Media. This book was released on 2007-03-24 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the current knowledge of fundamental as well as applied microbiology of amino acids. Coverage details the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The book also examines the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and as food and feed additives.
Book Synopsis Industrial Biotechnology by : Christoph Wittmann
Download or read book Industrial Biotechnology written by Christoph Wittmann and published by John Wiley & Sons. This book was released on 2017-04-10 with total page 789 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Download or read book Bioeconomy written by Iris Lewandowski and published by Springer. This book was released on 2017-12-11 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This book defines the new field of "Bioeconomy" as the sustainable and innovative use of biomass and biological knowledge to provide food, feed, industrial products, bioenergy and ecological services. The chapters highlight the importance of bioeconomy-related concepts in public, scientific, and political discourse. Using an interdisciplinary approach, the authors outline the dimensions of the bioeconomy as a means of achieving sustainability. The authors are ideally situated to elaborate on the diverse aspects of the bioeconomy. They have acquired in-depth experience of interdisciplinary research through the university’s focus on “Bioeconomy”, its contribution to the Bioeconomy Research Program of the federal state of Baden-Württemberg, and its participation in the German Bioeconomy Council. With the number of bioeconomy-related projects at European universities rising, this book will provide graduate students and researchers with background information on the bioeconomy. It will familiarize scientific readers with bioeconomy-related terms and give scientific background for economists, agronomists and natural scientists alike.
Book Synopsis Synthetic Biodegradable and Biobased Polymers by : Andreas Künkel
Download or read book Synthetic Biodegradable and Biobased Polymers written by Andreas Künkel and published by Springer Nature. This book was released on 2023-12-28 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the recent developments in synthetic biodegradable and biobased polymers. The syntheses of many polymer types such as polyesters and polyamides, and also their processing technologies are discussed herein, and new aspects from fundamental and from industrial research are covered. This combination of both perspectives within this volume will be of interest for many research scientists from academia and industry and also for lectures and teachers. Chapters ''BioPBSTM (Polybutylene succinate)'' and ''Polymer biodegradability 2.0: A holistic view on polymer biodegradation in natural and engineered environments'' are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. For further details see license information in the chapter.
Book Synopsis Handbook of Corynebacterium glutamicum by : Lothar Eggeling
Download or read book Handbook of Corynebacterium glutamicum written by Lothar Eggeling and published by CRC Press. This book was released on 2005-03-30 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important organisms in biotechnology, Corynebacterium glutamicum is currently used to produce 2 million tons of amino acids per year for a rapidly expanding market. Until now, research and information have been scattered among individual papers which are often difficult to locate in a timely manner. As the first complete comp
Book Synopsis Biotechnology of Natural Products by : Wilfried Schwab
Download or read book Biotechnology of Natural Products written by Wilfried Schwab and published by Springer. This book was released on 2017-11-16 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text comprehensively covers the analysis, enzymology, physiology and genetics of valuable natural products used in the food industry that are attractive targets for biotechnological production. The focus is on the recent advances made to achieve this goal. This unique work is the first book to focus on biotechnological production of important natural products in food additives, fragrances and flavorings, and other bioactive compounds in food. The chapters offer a deep insight into modern research and the development of low molecular weight natural products. Biotechnology of Natural Products covers products in the Phenolic, Terpenoid, and Alkaloid categories, providing a full overview of the biotechnology of food additives and other low molecular weight natural products. Gene clustering and the evolution of pathways are covered, as well as future perspectives on the topic. Due to limited oil resources and increasing consumer demand for naturalness, bioprocesses are increasingly needed to meet these requirements. Novel sophisticated technologies have facilitated the elucidation of new chemical molecules, their biosynthetic pathways and biological functions. This book provides researchers with a full overview of the technologies and processes involved in the biotechnology of natural products.
Book Synopsis Metabolic Engineering of Corynebacterium Glutamicum for the Production of L-aspartate and Its Derivatives Β-alanine and Ectoine by : Christian Ziert
Download or read book Metabolic Engineering of Corynebacterium Glutamicum for the Production of L-aspartate and Its Derivatives Β-alanine and Ectoine written by Christian Ziert and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Biobased Economy by : Hans Langeveld
Download or read book The Biobased Economy written by Hans Langeveld and published by Routledge. This book was released on 2012 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an illuminating framework as to how policy and market players could and should drive the development of a biobased economy that is effective, sustainable, fair and cost efficient. The result is an essential resource for all those working in or concerned with biobased industries, their policy or research.
