Synthetic Chemistry Of Amides

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Synthetic Chemistry of Amides

Author : Caleb Murphy
Publisher : NY Research Press
ISBN 13 : 9781647254544
Total Pages : 0 pages
Book Rating : 4.2/5 (545 download)

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Book Synopsis Synthetic Chemistry of Amides by : Caleb Murphy

Download or read book Synthetic Chemistry of Amides written by Caleb Murphy and published by NY Research Press. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amides are functional groups in which a carbonyl carbon atom is linked by a single bond to a nitrogen atom, and either a hydrogen or a carbon atom. The general formula of amide is RC (=O)NR, R", where R, R', and R" represent organic groups or hydrogen atoms. Some common examples of amides are benazamide, acetamide, nylon, paracetamol and dimethylformamide. The amide bond is found in many naturally occurring and synthetic compounds. There are several areas of chemistry such as biochemistry, organic synthesis, polymers and drug discovery, wherein the amide groups are used as the fundamental functional group. Amide groups can participate in a wide variety of transformations synthetically and are particularly versatile when exposed to electrochemical conditions. This book aims to shed light on the synthetic chemistry of amides. It presents researches and studies performed by experts across the globe. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this area of study.

Novel Synthetic Chemistry of Ureas and Amides

Author : Marc Hutchby
Publisher : Springer Science & Business Media
ISBN 13 : 3642320511
Total Pages : 179 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Novel Synthetic Chemistry of Ureas and Amides by : Marc Hutchby

Download or read book Novel Synthetic Chemistry of Ureas and Amides written by Marc Hutchby and published by Springer Science & Business Media. This book was released on 2012-08-30 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis, the author investigates the chemistry and application of molecules containing urea and amide bonds. These bonds are some of the strongest known and are fundamental to biological processes. The author describes his discovery that sterically hindered ureas undergo solvolysis at room temperature under neutral conditions. This is a remarkable finding, since ureas are inert under these conditions and a general rule of chemistry is that hindered substrates are less reactive. Remarkably, the author translates these results to the correspondingly sterically hindered amides. This thesis has resulted in a number of outstanding publications in high profile journals. The unique method for breaking urea and amide bonds developed in this study is likely to have far reaching consequences for biological protein manipulation.

Amide Bond Activation

Author : Michal Szostak
Publisher : MDPI
ISBN 13 : 3039212036
Total Pages : 466 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Amide Bond Activation by : Michal Szostak

Download or read book Amide Bond Activation written by Michal Szostak and published by MDPI. This book was released on 2019-07-12 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amide bond represents a privileged motif in chemistry. The recent years have witnessed an explosion of interest in the development of new chemical transformations of amides. These developments cover an impressive range of catalytic N–C bond activation in electrophilic, Lewis acid, radical, and nucleophilic reaction pathways, among other transformations. Equally relevant are structural and theoretical studies that provide the basis for chemoselective manipulation of amidic resonance. This monograph on amide bonds offers a broad survey of recent advances in activation of amides and addresses various approaches in the field.

Amide Bond Activation

Author : Michal Szostak
Publisher : John Wiley & Sons
ISBN 13 : 352734831X
Total Pages : 533 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Amide Bond Activation by : Michal Szostak

Download or read book Amide Bond Activation written by Michal Szostak and published by John Wiley & Sons. This book was released on 2022-10-10 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amide Bond Activation Comprehensive resource on the pivotal role of the amide bond in organic synthesis This book provides the reader with insight into the advances that have taken place in the field of amide bond activation. It focuses on both the fundamental structural properties of the amide bond and the synthetic reactions mediated by transition-metals. By discussing amide bond activation in terms of modern organic synthesis, the reader is provided with a thorough overview of the area and its crucial role in forging carbon-carbon and carbon-heteroatom bonds. Sample topics discussed within the work include: Cross-coupling of amides Amide bond activation by twisting and nitrogen pyramidalization Electrophilic amide bond functionalization Transition metal-catalyzed radical reactions of amides Amide bond esterification, hydrolysis and transamidation Classical bridged lactams and anomeric amides Computational studies of amide C-N bond activation Cross-coupling of esters by C-O activation The book is immensely valuable to synthetic chemists in academia and the pharmaceutical industry who wish to gain an in-depth understanding of the concept of amide bond activation.

Advances in the Use of Synthons in Organic Chemistry

Author : Alessandro Dondoni
Publisher : Elsevier
ISBN 13 : 1483100944
Total Pages : 240 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Advances in the Use of Synthons in Organic Chemistry by : Alessandro Dondoni

Download or read book Advances in the Use of Synthons in Organic Chemistry written by Alessandro Dondoni and published by Elsevier. This book was released on 2013-10-22 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the Use of Synthons in Organic Chemistry: A Research Annual, Volume 1 provides information pertinent to a useful reagent that can perform a certain chemical operation that is otherwise impossible or difficult to carry out. This book presents the developments on established synthons. Organized into four chapters, this volume begins with an overview of the significant role of the formyl group in synthetic methodologies, which has stimulated the search for other reagents. This text then describes trimethysilyldiazomethane as a stable and safe substitute for hazardous diazomethane. Other chapters consider the usefulness of trimethysilyldiazomethane in organic syntheses. This book discusses as well that malonic amides, silylenol ethers, malonic esters, and tetra-donor-substituted allenes serve as synthetic equivalents for the dianions of malonic esters, ketones, and malonic amides. The final chapter deals with the synthesis of biologically-active compounds, which has been one of the major challenges for organic chemists. This book is a valuable resource for practicing synthetic chemists.

The Chemistry of Amides

Author : Jacob Zabicky
Publisher :
ISBN 13 :
Total Pages : 927 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis The Chemistry of Amides by : Jacob Zabicky

Download or read book The Chemistry of Amides written by Jacob Zabicky and published by . This book was released on 1970 with total page 927 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Organic Chemistry

Author : Francis A. Carey
Publisher : Springer Science & Business Media
ISBN 13 : 1461397979
Total Pages : 817 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Advanced Organic Chemistry by : Francis A. Carey

Download or read book Advanced Organic Chemistry written by Francis A. Carey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main theme of Part B is the description of synthetically useful reactions and the illustration of their application. We have attempted to update the material to reflect the most important advances in synthetic methodology. Because of the extensive developments in the use of organic derivatives of transition metals, as well as of silicon and tin, we have separated the organometallic material into three chapters. Chapter 7 emphasizes organolithium and organomagnesium chemistry and also considers the group lIB metals. Transition metal chemistry is discussed in Chapter 8, with emphasis on copper and palladium intermediates. In Chapter 9, the carbon-carbon bond-forming reactions of organoboranes, silanes, and stannanes are discussed. The increased importance of free-radical reactions in synthesis has led to the incorporation of a section on radical reactions into Chapter 10, in which carbocations, carbenes, and nitrenes are also discussed. Certainly a major advance in synthetic chemistry during the 1980s was the development of methods for enantioselective synthesis. We have increased the level of attention to stereochemistry in the discussion of many reactions. In areas in which new stereoselective methods have been well developed, such as in aldol condensa tions, hydroboration, catalytic reduction, and epoxidation, we discuss these methods. The final chapter discusses some of the general issues which must be addressed in multistep synthesis and provides some illustrative syntheses which can provide the basis for more detailed study of this aspect of synthetic chemistry.

The Amide Linkage

Author : Arthur Greenberg
Publisher : John Wiley & Sons
ISBN 13 : 9780471420255
Total Pages : 672 pages
Book Rating : 4.4/5 (22 download)

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Book Synopsis The Amide Linkage by : Arthur Greenberg

Download or read book The Amide Linkage written by Arthur Greenberg and published by John Wiley & Sons. This book was released on 2002-11-11 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative reference to an important and ubiquitous chemical linkage The amide linkage is one of the most fundamental and widespread chemical bonds in nature, underlying the properties of a vast array of organic molecules, polymers, and materials, including peptides and proteins. Arthur Greenberg, Curt Breneman, and Joel Liebman's peerless text provides comprehensive coverage of the experimental, structural, and computational findings that shed light on the chemical and physical properties of the amide linkage, as well as its emerging applications in materials and biotechnology. Chapters in The Amide Linkage highlight how this chemical bond factors in the design of enzyme inhibitors, cyclic peptides, antibacterial agents, and emerging nanotechnology applications. This one-of-a-kind study also: * Discusses selected aspects of chemical reactions, structure, bonding, and energetics of the amide bond, including amide rotational barriers, stereochemistry, complexation, spectroscopy, and thermochemistry * Presents specific applications to supramolecular and stereospecific synthesis * Discusses key aspects of peptide and protein chemistry-such as molecular recognition, conformation, and folding-in terms of the amide linkage * Includes chapters contributed by numerous eminent chemists and biochemists Organic, medicinal, polymer, and physical chemists, as well as biochemists and materials scientists, will find The Amide Linkage to be an invaluable addition to their professional libraries.

Practical Synthetic Organic Chemistry

Author : Stéphane Caron
Publisher : John Wiley & Sons
ISBN 13 : 1119448859
Total Pages : 850 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Practical Synthetic Organic Chemistry by : Stéphane Caron

Download or read book Practical Synthetic Organic Chemistry written by Stéphane Caron and published by John Wiley & Sons. This book was released on 2020-02-05 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale

Organic Synthesis

Author : Belakatte Parameshwarappa Nandeshwarappa
Publisher : BoD – Books on Demand
ISBN 13 : 1789859433
Total Pages : 250 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Organic Synthesis by : Belakatte Parameshwarappa Nandeshwarappa

Download or read book Organic Synthesis written by Belakatte Parameshwarappa Nandeshwarappa and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.

Practical Functional Group Synthesis

Author : Robert A. Stockland, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 1118612809
Total Pages : 697 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Practical Functional Group Synthesis by : Robert A. Stockland, Jr.

Download or read book Practical Functional Group Synthesis written by Robert A. Stockland, Jr. and published by John Wiley & Sons. This book was released on 2016-01-26 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical handbook for chemists performing bond forming reactions, this book features useful information on the synthesis of common functional groups in organic chemistry. • Details modern functional group synthesis through carbon-heteroelement (N, O, P, S, B, halogen) bond forming reactions with a focus on operational simplicity and sustainability. • Summarizes key and recent developments – which are otherwise scattered across journal literature – into a single source • Contains over 100 detailed preparations of common functional groups • Included 25 troubleshooting guides with suggestions and potential solutions to common problems. • Complements the text in enhanced ebook editions with tutorial videos where the author provides an introduction to microwave assisted chemistry

Exercises in Organic Synthesis Based on Synthetic Drugs

Author : Marcus Vinícius Nora de Souza
Publisher : Bentham Science Publishers
ISBN 13 : 9811487545
Total Pages : 250 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Exercises in Organic Synthesis Based on Synthetic Drugs by : Marcus Vinícius Nora de Souza

Download or read book Exercises in Organic Synthesis Based on Synthetic Drugs written by Marcus Vinícius Nora de Souza and published by Bentham Science Publishers. This book was released on 2020-12-23 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercises in Organic Synthesis Based on Synthetic Drugs presents information on topics about the synthesis of biologically active compounds which are used against a range of diseases in both humans and animals. Topics are supplemented by notes and exercises for students to stimulate inquiry and learning in the academic environment. Readers will be equipped with basic knowledge of synthetic techniques used in organic chemistry and pharmaceutical research and development. Key Features: - Presents information about different techniques and strategies for the synthesis of organic compounds - Covers a broad range of biologically active compounds - Easy to read topical presentation - Exercises, with answers, designed for improving concepts in organic synthesis and medicinal chemistry - Wide range of bibliographic references for further reading and exercises presented, Exercises in Organic Synthesis Based on Synthetic Drugs is an essential textbook for students in beginner level courses in organic chemistry, organic synthesis and medicinal chemistry.

Chemoselective Nucleophilic α-Amination of Amides

Author : Miran Lemmerer
Publisher : Springer Nature
ISBN 13 : 3658300205
Total Pages : 60 pages
Book Rating : 4.6/5 (583 download)

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Book Synopsis Chemoselective Nucleophilic α-Amination of Amides by : Miran Lemmerer

Download or read book Chemoselective Nucleophilic α-Amination of Amides written by Miran Lemmerer and published by Springer Nature. This book was released on 2020-04-03 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team. The Author: Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria.

Compendium of Organic Synthetic Methods, Volume 13

Author : Michael B. Smith
Publisher : John Wiley & Sons
ISBN 13 : 1118791509
Total Pages : 740 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Compendium of Organic Synthetic Methods, Volume 13 by : Michael B. Smith

Download or read book Compendium of Organic Synthetic Methods, Volume 13 written by Michael B. Smith and published by John Wiley & Sons. This book was released on 2014-07-07 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Compendium of Organic Synthetic Methods serves as a handy desktop reference for organic chemists to browse new reactions and transformations of interest, facilitating the search for functional group transformations in the original literature of organic chemistry. Volume 13 contains both functional group transformations and carbon-carbon bond forming reactions from the literature in the years 2005-8. It presents examples of published reactions for the preparation of monofunctional compounds. The Compendium of Organic Synthetic Methods series facilitates the search for quality, selected functional group transformations, organized by reacting functional group of starting material and functional group formed, with full references to each reaction Presents examples of published reactions for the preparation of monofunctional compounds from the literature of 2005-8 Provides a handy reference and a valuable tool to the working organic chemist, allowing a quick check of known organic transformations Stringent criteria for inclusion of reactions, including real synthetic utility of reactions, reagents readily available or easily prepared and handled in the laboratory

Metal Amide Chemistry

Author : Michael Lappert
Publisher : John Wiley & Sons
ISBN 13 : 9780470740378
Total Pages : 370 pages
Book Rating : 4.7/5 (43 download)

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Book Synopsis Metal Amide Chemistry by : Michael Lappert

Download or read book Metal Amide Chemistry written by Michael Lappert and published by John Wiley & Sons. This book was released on 2008-12-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognised leaders in the field, Metal Amide Chemistry is the authoritative survey of this important class of compounds, the first since Lappert and Power’s 1980 book “Metal and Metalloid Amides.” An introduction to the topic is followed by in-depth discussions of the amide compounds of: alkali metals alkaline earth metals zinc, cadmium and mercury the transition metals group 3 and lanthanide metals group 13 metals silicon and the group 14 metals group 15 metals the actinide metals Accompanied by a substantial bibliography, this is an essential guide for researchers and advanced students in academia and research working in synthetic organometallic, organic and inorganic chemistry, materials chemistry and catalysis.

Principles of Organic Chemistry

Author : Robert J. Ouellette
Publisher : Academic Press
ISBN 13 : 0128026340
Total Pages : 498 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Organic Chemistry by : Robert J. Ouellette

Download or read book Principles of Organic Chemistry written by Robert J. Ouellette and published by Academic Press. This book was released on 2015-02-13 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization

Imides

Author : Frederick A. Luzzio
Publisher : Elsevier
ISBN 13 : 0128156767
Total Pages : 470 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Imides by : Frederick A. Luzzio

Download or read book Imides written by Frederick A. Luzzio and published by Elsevier. This book was released on 2019-05-17 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imides: Medicinal, Agricultural, Synthetic Applications and Natural Products Chemistry provides a comprehensive overview of imides being developed as pharmaceuticals or experimental therapeutics. Featuring a diverse range of experts in the field of imides, each chapter reviews the state-of-the-art, including the isolation and identification of naturally-occurring imides, as well as the total synthesis of imide natural products. As there is a need for a comprehensive review of imides as a class of naturally-occurring, biologically active molecules, this book will be invaluable to those in pharmaceuticals, academia, and anyone looking for clinical applications. - Features cutting-edge research in the field of imides for pharmaceutical and experimental therapeutic applications - Includes coverage of naturally occurring imides, along with medicinal chemistry-inspired imides - Focuses on the presentation of selected targets for their complex multistep synthesis - Discusses new reagents and strategies for synthesis - Includes contributions from leading experts in the field of imide research, working in both natural product chemistry and medicinal chemistry