Synthetic Biology Genetics And Advanced Topics

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Biodefense in the Age of Synthetic Biology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309465184
Total Pages : 189 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Advances in Synthetic Biology

Author : Vijai Singh
Publisher : Springer Nature
ISBN 13 : 9811500819
Total Pages : 349 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Advances in Synthetic Biology by : Vijai Singh

Download or read book Advances in Synthetic Biology written by Vijai Singh and published by Springer Nature. This book was released on 2020-04-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Synthetic Biology, Genetics and Advanced Topics

Author : Edenilson Brandl
Publisher : Edenilson Brandl
ISBN 13 :
Total Pages : 515 pages
Book Rating : 4./5 ( download)

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Book Synopsis Synthetic Biology, Genetics and Advanced Topics by : Edenilson Brandl

Download or read book Synthetic Biology, Genetics and Advanced Topics written by Edenilson Brandl and published by Edenilson Brandl. This book was released on with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology is a scientific discipline that has the potential to revolutionize the way we understand and manipulate life. Combining knowledge from biology, genetics, engineering and computing, Synthetic Biology opens up new possibilities for creating personalized biological systems, with applications ranging from regenerative medicine to the production of biofuels. In this book, we will explore the principles, techniques, and applications of synthetic biology, with the aim of providing a comprehensive and up-to-date overview of this ever-evolving field. Throughout the chapters, we will delve into the molecular foundations of Synthetic Biology, exploring the biological components and processes involved in building synthetic biological systems. We will present several applications of Synthetic Biology in different sectors, highlighting its role in the pharmaceutical industry, in the production of biofuels, in the development of personalized vaccines and in regenerative medicine. We will see how the manipulation of synthetic stem cells can revolutionize the area of tissue regeneration and how metabolic engineering allows us to design microorganisms capable of producing valuable compounds. Bioinformatics plays a crucial role in Synthetic Biology, and we will dedicate a chapter to exploring how the analysis of genomic data and the use of bioinformatics algorithms contribute to the advancement of this discipline. In addition, we will cover topics such as genome editing using CRISPR technology, synthetic protein engineering, and directed evolution in the laboratory. With the advancement of technology, it has become possible to manufacture living tissue in the laboratory, and we will discuss biofabrication and 3D printing of living tissue, as well as the use of microfluidics in the manipulation and analysis of synthetic biological systems on a microscopic scale. We will also address ethical and biosafety issues related to Synthetic Biology, recognizing the importance of a responsible approach in all its applications. This book is intended for students, researchers, and practitioners interested in exploring the frontiers of synthetic biology. We hope it will be an inspiring source of knowledge, awakening the curiosity and innovative spirit of all readers. We invite you to embark on this exciting journey through Synthetic Biology, in search of a deeper understanding of life and its transformative possibilities.

Positioning Synthetic Biology to Meet the Challenges of the 21st Century

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309225868
Total Pages : 80 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Positioning Synthetic Biology to Meet the Challenges of the 21st Century by : National Research Council

Download or read book Positioning Synthetic Biology to Meet the Challenges of the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2013-08-05 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology -- unlike any research discipline that precedes it -- has the potential to bypass the less predictable process of evolution to usher in a new and dynamic way of working with living systems. Ultimately, synthetic biologists hope to design and build engineered biological systems with capabilities that do not exist in natural systems -- capabilities that may ultimately be used for applications in manufacturing, food production, and global health. Importantly, synthetic biology represents an area of science and engineering that raises technical, ethical, regulatory, security, biosafety, intellectual property, and other issues that will be resolved differently in different parts of the world. As a better understanding of the global synthetic biology landscape could lead to tremendous benefits, six academies -- the United Kingdom's Royal Society and Royal Academy of Engineering, the United States' National Academy of Sciences and National Academy of Engineering, and the Chinese Academy of Science and Chinese Academy of Engineering -- organized a series of international symposia on the scientific, technical, and policy issues associated with synthetic biology. Positioning Synthetic Biology to Meet the Challenges of the 21st Century summarizes the symposia proceedings.

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Regenesis

Author : George M Church
Publisher : Basic Books
ISBN 13 : 0465038654
Total Pages : 305 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Regenesis by : George M Church

Download or read book Regenesis written by George M Church and published by Basic Books. This book was released on 2014-04-08 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Systems Biology and Synthetic Biology

Author : Pengcheng Fu
Publisher : Wiley-AIChE
ISBN 13 : 9780471767787
Total Pages : 658 pages
Book Rating : 4.7/5 (677 download)

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Book Synopsis Systems Biology and Synthetic Biology by : Pengcheng Fu

Download or read book Systems Biology and Synthetic Biology written by Pengcheng Fu and published by Wiley-AIChE. This book was released on 2009-04-20 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.

Synthetic Biology — A Primer

Author :
Publisher : World Scientific
ISBN 13 : 1783268816
Total Pages : 196 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Synthetic Biology — A Primer by :

Download or read book Synthetic Biology — A Primer written by and published by World Scientific. This book was released on 2015-08-24 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology — A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems. Examples of cutting-edge applications designed using synthetic biology principles are presented, including: the production of novel, microbial synthesis of pharmaceuticals and fine chemicalsthe design and implementation of biosensors to detect infections and environmental waste. The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research. Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology. Contents:List of ContributorsPrefaceIntroduction to BiologyBasic Concepts in Engineering BiologyFoundational TechnologiesMinimal Cells and Synthetic LifeParts, Devices and SystemsModelling Synthetic Biology SystemsApplications of Designed Biological SystemsiGEMThe Societal Impact of Synthetic BiologyAppendices:Proforma of Common Laboratory TechniquesGlossaryIndex Readership: Students, professionals, researchers in biotechnology and bioengineering. Keywords:Synthetic Biology;Engineering Principles;Biosociety;Biological Engineering;BiotechnologyKey Features:The book is written in a way that is accessible to students and researchers from different disciplinesThe authors are part of the internationally recognised Centre for Synthetic Biology and Innovation and are among the leaders in this field

Genetics Fundamentals Notes

Author : Debasish Kar
Publisher : Springer Nature
ISBN 13 : 9811670412
Total Pages : 1149 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Genetics Fundamentals Notes by : Debasish Kar

Download or read book Genetics Fundamentals Notes written by Debasish Kar and published by Springer Nature. This book was released on 2022-10-06 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date and comprehensive textbook is essential reading material for advanced undergraduate and graduate students with a course module in genetics and developmental biology. The book provides clear, concise, and rigorous foundational concepts of genetics. It opens with an introductory chapter that provides an overview of genetics. The book includes separate and detailed sections on classical genetics, molecular genetics, and population genetics. It covers basic and foundational principles such as Mendelian genetics, chromosomal theory, transcription, translation, mutation, and gene regulation. It further includes chapters on advanced topics such as molecular genetic techniques, genomics, and applied molecular genetics. The concluding section includes chapters on population genetics, developmental genetics, and evolutionary genetics. The chapters are written by authors with in-depth knowledge of the field. The book is replete with interesting examples, case studies, questions and suggested reading. It is useful to students and course instructors in the field of human genetics, developmental biology, life sciences, and biotechnology. It is also meant for researchers who wish to further their understanding about the fundamental concepts of genetics.

Genetic Techniques for Biological Research

Author : Corinne A. Michels
Publisher : John Wiley & Sons
ISBN 13 : 9780471899198
Total Pages : 264 pages
Book Rating : 4.8/5 (991 download)

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Book Synopsis Genetic Techniques for Biological Research by : Corinne A. Michels

Download or read book Genetic Techniques for Biological Research written by Corinne A. Michels and published by John Wiley & Sons. This book was released on 2002-06-10 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project.

Advanced Molecular Biology

Author : Richard M. Twyman
Publisher : Taylor & Francis
ISBN 13 : 9781859961414
Total Pages : 499 pages
Book Rating : 4.9/5 (614 download)

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Book Synopsis Advanced Molecular Biology by : Richard M. Twyman

Download or read book Advanced Molecular Biology written by Richard M. Twyman and published by Taylor & Francis. This book was released on 1998 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Molecular Biology - A Concise Reference provides in-depth coverage of 30 essential topics in molecular biology with particular focus on genetic information and its expression. The book emphasizes unifying principles and mechanisms, with comprehensive use of tables and boxes to summarize experimental data, gene and protein functions. Advanced Molecular Biology - A Concise Reference is written for upper level undergraduates, postgraduates and academics with an interest in molecular biology who need a convenient entry into the field.

BioBuilder

Author : Natalie Kuldell PhD.
Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1491907533
Total Pages : 238 pages
Book Rating : 4.4/5 (919 download)

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Book Synopsis BioBuilder by : Natalie Kuldell PhD.

Download or read book BioBuilder written by Natalie Kuldell PhD. and published by "O'Reilly Media, Inc.". This book was released on 2015-06-22 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene

Zero to Genetic Engineering Hero

Author : Justin Pahara
Publisher : Maker Media, Inc.
ISBN 13 : 1680457675
Total Pages : 336 pages
Book Rating : 4.6/5 (84 download)

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Book Synopsis Zero to Genetic Engineering Hero by : Justin Pahara

Download or read book Zero to Genetic Engineering Hero written by Justin Pahara and published by Maker Media, Inc.. This book was released on 2021-08-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zero to Genetic Engineering Hero is made to provide you with a first glimpse of the inner-workings of a cell. It further focuses on skill-building for genetic engineering and the Biology-as-a-Technology mindset (BAAT). This book is designed and written for hands-on learners who have little knowledge of biology or genetic engineering. This book focuses on the reader mastering the necessary skills of genetic engineering while learning about cells and how they function. The goal of this book is to take you from no prior biology and genetic engineering knowledge toward a basic understanding of how a cell functions, and how they are engineered, all while building the skills needed to do so.

Plant Biotechnology and Genetics

Author : C. Neal Stewart, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 1118820126
Total Pages : 452 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Plant Biotechnology and Genetics by : C. Neal Stewart, Jr.

Download or read book Plant Biotechnology and Genetics written by C. Neal Stewart, Jr. and published by John Wiley & Sons. This book was released on 2016-03-21 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused on basics and processes, this textbook teaches plant biology and agriculture applications with summary and discussion questions in each chapter. Updates each chapter to reflect advances / changes since the first edition, for example: new biotechnology tools and advances, genomics and systems biology, intellectual property issues on DNA and patents, discussion of synthetic biology tools Features autobiographical essays from eminent scientists, providing insight into plant biotechnology and careers Has a companion website with color images from the book and PowerPoint slides Links with author's own website that contains teaching slides and graphics for professors and students: http://bit.ly/2CI3mjp

Advanced Molecular Genetics

Author : A. Pühler
Publisher : Springer
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advanced Molecular Genetics by : A. Pühler

Download or read book Advanced Molecular Genetics written by A. Pühler and published by Springer. This book was released on 1984 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applied Molecular Genetics

Author : Roger L. Miesfeld
Publisher : John Wiley & Sons
ISBN 13 : 0471156760
Total Pages : 308 pages
Book Rating : 4.4/5 (711 download)

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Book Synopsis Applied Molecular Genetics by : Roger L. Miesfeld

Download or read book Applied Molecular Genetics written by Roger L. Miesfeld and published by John Wiley & Sons. This book was released on 1999-04-13 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text explains the key biochemical and cell biological principles behind some of today's most commonly used applications of molecular genetics, using clear terms and well-illustrated flow schemes. The book is divided into several sections and moves from basic to advanced topics while providing a concise overview of fundamental concepts in modern biotechnology. Each chapter concludes with a Laboratory Practicum describing a hypothetical research objective and the sequence of steps that are most often used to investigate biological questions using molecular genetic methods. In addition, the book provides informative summaries of the latest advances in molecular genetics, using attractive illustrations and a comprehensive reference list. This text also introduces the use of Internet resources through the World Wide Web as a powerful new tool in molecular genetic research. Seven appendices are included in the book, providing a convenient information resource for properties of nucleic acids, protein and restriction enzymes, a description of common E. coli genetic markers and gel electrophoresis parameters, as well as a list of useful Internet address sites.

Genetics and Molecular Biology

Author : Robert F. Schleif
Publisher :
ISBN 13 :
Total Pages : 724 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetics and Molecular Biology by : Robert F. Schleif

Download or read book Genetics and Molecular Biology written by Robert F. Schleif and published by . This book was released on 1993 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first edition of Genetics and Molecular Biology, renowned researcher and award-winning teacher Robert Schleif produced a unique and stimulating text that was a notable departure from the standard compendia of facts and observations. Schleif's strategy was to present the underlying fundamental concepts of molecular biology with clear explanations and critical analysis of well-chosen experiments. The result was a concise and practical approach that offered students a real understanding of the subject. This second edition retains that valuable approach--with material thoroughly updated to include an integrated treatment of prokaryotic and eukaryotic molecular biology. Genetics and Molecular Biology is copiously illustrated with two-color line art. Each chapter includes an extensive list of important references to the primary literature, as well as many innovative and thought-provoking problems on material covered in the text or on related topics. These help focus the student's attention of a variety of critical issues. Solutions are provided for half of the problems. Praise for the first edition: "Schleif's Genetics and Molecular Biology... is a remarkable achievement. It is an advanced text, derived from material taught largely to postgraduates, and will probably be thought best suited to budding professionals in molecular genetics. In some ways this would be a pity, because there is also gold here for the rest of us... The lessons here in dealing with the information explosion in biology are that an ounce of rationale is worth a pound of facts and that, for educational value, there is nothing to beat an author writing about stuff he knows from theinside."--Nature. "Schleif presents a quantitative, chemically rigorous approach to analyzing problems in molecular biology. The text is unique and clearly superior to any currently available."--R.L. Bernstein, San Francisco State University. "The greatest strength is the author's ability to challenge the student to become involved and get below the surface."--Clifford Brunk, UCLA