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Synthetic Biology For The Sustainable Production Of Biochemicals In Engineered Microbes
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Book Synopsis Synthetic Biology for the Sustainable Production of Biochemicals in Engineered Microbes by : Shuobo Shi
Download or read book Synthetic Biology for the Sustainable Production of Biochemicals in Engineered Microbes written by Shuobo Shi and published by Frontiers Media SA. This book was released on 2022-09-23 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Engineering of Microbial Biosynthetic Pathways by : Vijai Singh
Download or read book Engineering of Microbial Biosynthetic Pathways written by Vijai Singh and published by Springer Nature. This book was released on 2020-07-16 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.
Book Synopsis Biomolecular Engineering Solutions for Renewable Specialty Chemicals by : R. Navanietha Krishnaraj
Download or read book Biomolecular Engineering Solutions for Renewable Specialty Chemicals written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-11-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover biomolecular engineering technologies for the production of biofuels, pharmaceuticals, organic and amino acids, vitamins, biopolymers, surfactants, detergents, and enzymes In Biomolecular Engineering Solutions for Renewable Specialty Chemicals, distinguished researchers and editors Drs. R. Navanietha Krishnaraj and Rajesh K. Sani deliver a collection of insightful resources on advanced technologies in the synthesis and purification of value-added compounds. Readers will discover new technologies that assist in the commercialization of the production of value-added products. The editors also include resources that offer strategies for overcoming current limitations in biochemical synthesis, including purification. The articles within cover topics like the rewiring of anaerobic microbial processes for methane and hythane production, the extremophilic bioprocessing of wastes to biofuels, reverse methanogenesis of methane to biopolymers and value-added products, and more. The book presents advanced concepts and biomolecular engineering technologies for the production of high-value, low-volume products, like therapeutic molecules, and describes methods for improving microbes and enzymes using protein engineering, metabolic engineering, and systems biology approaches for converting wastes. Readers will also discover: A thorough introduction to engineered microorganisms for the production of biocommodities and microbial production of vanillin from ferulic acid Explorations of antibiotic trends in microbial therapy, including current approaches and future prospects, as well as fermentation strategies in the food and beverage industry Practical discussions of bioactive oligosaccharides, including their production, characterization, and applications In-depth treatments of biopolymers, including a retrospective analysis in the facets of biomedical engineering Perfect for researchers and practicing professionals in the areas of environmental and industrial biotechnology, biomedicine, and the biological sciences, Biomolecular Engineering Solutions for Renewable Specialty Chemicals is also an invaluable resource for students taking courses involving biorefineries, biovalorization, industrial biotechnology, and environmental biotechnology.
Book Synopsis Microbial Cell Factories Engineering for Production of Biomolecules by : Vijai Singh
Download or read book Microbial Cell Factories Engineering for Production of Biomolecules written by Vijai Singh and published by Academic Press. This book was released on 2021-02-13 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs
Book Synopsis Biorefinery Production Technologies for Chemicals and Energy by : Arindam Kuila
Download or read book Biorefinery Production Technologies for Chemicals and Energy written by Arindam Kuila and published by John Wiley & Sons. This book was released on 2020-10-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers almost all of the diverse aspects of utilizing lignocellulosic biomass for valuable biorefinery product development of chemicals, alternative fuels and energy. The world has shifted towards sustainable development for the generation of energy and industrially valuable chemicals. Biorefinery plays an important role in the integration of conversion process with high-end equipment facilities for the generation of energy, fuels and chemicals. The book is divided into four parts. The first part, "Basic Principles of Biorefinery," covers the concept of biorefinery, its application in industrial bioprocessing, the utilization of biomass for biorefinery application, and its future prospects and economic performance. The second part, "Biorefinery for Production of Chemicals," covers the production of bioactive compounds, gallic acid, C4, C5, and C6 compounds, etc., from a variety of substrates. The third part, "Biorefinery for Production of Alternative Fuel and Energy," covers sustainable production of bioethanol, biodiesel, and biogas from different types of substrates. The last part of this book discusses sequential utilization of wheat straw, material balance, and biorefinery approach. The approaches presented in this book will help readers/users from different areas like process engineering and biochemistry to plan integrated and inventive methods to trim down the expenditure of the industrial manufacture process to accomplish cost-effective feasible products in biorefinery.
Book Synopsis Biomedical Engineering by : Phil Gilberts
Download or read book Biomedical Engineering written by Phil Gilberts and published by Freegulls Publishing House. This book was released on with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical engineering integrates the principles of biology, chemistry, and engineering to develop processes for the large-scale production of valuable biochemicals. This interdisciplinary field plays a crucial role in industries such as pharmaceuticals, biotechnology, food and beverage, and environmental engineering. One of the fundamental aspects of biochemical engineering is fermentation, which involves the controlled growth of microorganisms like bacteria, yeast, or fungi to produce desired compounds. These microorganisms can be genetically engineered or selected for their ability to synthesize specific products, such as antibiotics, vitamins, or biofuels. Biocatalysis is another key area within biochemical engineering, focusing on the use of enzymes or whole cells to catalyze chemical reactions. By harnessing the specificity and efficiency of biological catalysts, biocatalysis offers environmentally friendly and cost-effective solutions for chemical synthesis and manufacturing processes. Bioseparation techniques are essential for isolating and purifying target biomolecules from complex mixtures produced during fermentation or biocatalytic reactions. These techniques include filtration, chromatography, centrifugation, and membrane processes, which enable the recovery of high-purity products for further downstream processing. Bioprocess design involves the optimization of various parameters such as reactor configuration, operating conditions, and media composition to maximize product yield, quality, and efficiency. Computational modeling and simulation techniques play a crucial role in predicting and optimizing bioprocess performance, allowing engineers to design robust and scalable production systems. Overall, biochemical engineering combines scientific principles with engineering methodologies to develop sustainable and economically viable processes for the production of biochemicals with diverse applications in medicine, agriculture, energy, and the environment.
Book Synopsis Sustainable Production Innovations by : Alok Kumar Patel
Download or read book Sustainable Production Innovations written by Alok Kumar Patel and published by John Wiley & Sons. This book was released on 2023-08-02 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: SUSTAINABLE PRODUCTION INNOVATIONS Presenting the latest technologies and practices in this ever-changing field, this groundbreaking new volume covers the gambit for providing solutions and practical applications of smart and efficient energy systems. The global and climate changes we are witnessing are primarily driven by factors such as rising population, economic growth, and industrialization. These changes have led to an increase in atmospheric CO2, pollution, deforestation, water scarcity, and hunger, among other pressing issues. To ensure a green and sustainable future, it is crucial to harness renewable resources for the production of fuels, chemicals, and materials. The book, Sustainable Production Innovations, addresses several bioprocesses that are integral to our daily lives, tackling important topics such as biofuel production, energy and food security, and wastewater management. The commercial interest in biotechnological processes has grown significantly due to their ability to utilize biocatalysts such as enzymes, bacteria, plant cells, or animal cells in bioreactors for the production of medications, health supplements, foods, biofuels, and chemicals. Switching to bioproducts offers key benefits such as the sustainability of third-generation biofuels, CO2 sequestration, effective waste utilization, and meeting the increasing demand for clean water. The book explores various procedures used in biomass biorefineries and bioprocessing for the production of biofuels, biobased chemicals, and bioproducts. It also delves into advancements in utilizing oleaginous microorganisms for biofuels and nutraceuticals, biological wastewater treatment, and microplastic detection techniques in water. Additionally, the book covers topics such as biolubricant technologies, bioprocessing of agricultural and forest waste, biotechnological approaches in the cosmetic industry, and large-scale applications of nanomaterials for water treatment. Authored by experts from leading biotechnology research groups around the world, the book comprises 13 chapters featuring the latest research in each subject. It is a valuable resource for scholars in chemical engineering, applied microbiology, biotechnology, agricultural biotechnology, environmental biotechnology, and related fields, offering new insights into the sustainable use of renewable energy and biochemicals. Professionals, including biochemical engineers, phycologists, bioprocess engineers, chemical engineers, scientists, and researchers in the water, food, pharmaceutical, and renewable energy industries will find this book beneficial. Likewise, students and faculty in the chemical engineering and energy departments will gain valuable knowledge from its contents.
Book Synopsis Biomanufacturing for Sustainable Production of Biomolecules by : Vijai Singh
Download or read book Biomanufacturing for Sustainable Production of Biomolecules written by Vijai Singh and published by Springer. This book was released on 2024-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules. This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.
Book Synopsis Synthetic biology applications in industrial microbiology by : Weiwen Zhang
Download or read book Synthetic biology applications in industrial microbiology written by Weiwen Zhang and published by Frontiers E-books. This book was released on 2014-12-03 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.
Book Synopsis Synthetic Biology – Metabolic Engineering by : Huimin Zhao
Download or read book Synthetic Biology – Metabolic Engineering written by Huimin Zhao and published by Springer. This book was released on 2017-10-27 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Download or read book Microbial Synthetic Biology written by and published by Elsevier. This book was released on 2013-11-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue. Authority or expertise of contributors lLnks to websites for the design and modelling of microbes and microbial metabolism First volume to address the practical issues Discussion on responsible innovation
Book Synopsis One-Carbon Feedstocks for Sustainable Bioproduction by : An-Ping Zeng
Download or read book One-Carbon Feedstocks for Sustainable Bioproduction written by An-Ping Zeng and published by Springer Nature. This book was released on 2022-05-31 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive review of the latest developments, challenges and trends in C1-based (one-carbon based) bioproduction, and it presents an authoritative account of one-carbon compounds as promising alternative microbial feedstocks. The book starts with a perspective on the future of C1 compounds as alternative feedstocks for microbial growth, and their vital role in the establishment of a sustainable circular carbon economy, followed by several chapters in which expert contributors discuss about the recent strategies and address key challenges regarding one or more C1 feedstocks. The book covers topics such as acetogenic production from C1 feedstocks, aerobic carboxydotrophic bacteria potential in industrial biotechnology, bioconversion of methane to value-added compounds, combination of electrochemistry and biology to convert C1 compounds, and bioprocesses based on C1-mixotrophy. Particular attention is given to the current metabolic engineering, systems biology, and synthetic biology strategies applied in this field.
Book Synopsis Systems Biology and Synthetic Biology by : Pengcheng Fu
Download or read book Systems Biology and Synthetic Biology written by Pengcheng Fu and published by Wiley-AIChE. This book was released on 2009-08-13 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.
Book Synopsis Microbial Engineering for Therapeutics by : Mrutyunjay Suar
Download or read book Microbial Engineering for Therapeutics written by Mrutyunjay Suar and published by Springer Nature. This book was released on 2022-10-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
Book Synopsis Quantitative Systems Biology for Engineering Organisms and Pathways by : Hilal Taymaz-Nikerel
Download or read book Quantitative Systems Biology for Engineering Organisms and Pathways written by Hilal Taymaz-Nikerel and published by Frontiers Media SA. This book was released on 2016-05-27 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studying organisms as a whole for potential metabolic(ally) engineering of organisms for production of (bio)chemicals is essential for industrial biotechnology. To this end, integrative analysis of different –omics measurements (transciptomics, proteomics, metabolomics, fluxomics) provides invaluable information. Combination of experimental top-down and bottom-up approaches with powerful analytical tools/techniques and mathematical modeling, namely (quantitative) systems biology, currently making the state of art of this discipline, is the only practice that would improve our understanding for the purpose. The use of high-throughput technologies induced the required development of many bioinformatics tools and mathematical methods for the integration of obtained data. Such research is significant since compiling information from different levels of a living system and connecting them is not an easy task. In particular, construction of dynamic models for product improvement has been one of the goals of many research groups. In this Research Topic, we summarize and bring a general review of the most recent and relevant contributions in quantitative systems biology applied in metabolic modeling perspective. We want to make special emphasis on the techniques that can be widely implemented in regular scientific laboratories and in those works that include theoretical presentations. With this Research Topic we discuss the importance of applying systems biology approaches for finding metabolic engineering targets for the efficient production of the desired biochemical integrating information from genomes and networks to industrial production. Examples and perspectives in the design of new industrially relevant chemicals, e.g. increased titer/productivity/yield of (bio)chemicals, are welcome. Addition to the founded examples, potential new techniques that would frontier the research will be part of this topic. The significance of multi ‘omics’ approaches to understand/uncover the pathogenesis/mechanisms of metabolic disesases is also one of the main topics.
Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Book Synopsis Environmental Geoinformatics by : Joseph Awange
Download or read book Environmental Geoinformatics written by Joseph Awange and published by Springer. This book was released on 2018-12-08 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition includes updated chapters from the first edition as well as five additional new chapters (Light detection and ranging (LiDAR), CORONA historical de-classified products, Unmanned Aircraft Vehicles (UAVs), GNSS-reflectometry and GNSS applications to climate variability), shifting the main focus from monitoring and management to extreme hydro-climatic and food security challenges and exploiting big data. Since the publication of first edition, much has changed in terms of technology, and the demand for geospatial data has increased with the advent of the big data era. For instance, the use of laser scanning has advanced so much that it is unavoidable in most environmental monitoring tasks, whereas unmanned aircraft vehicles (UAVs)/drones are emerging as efficient tools that address food security issues as well as many other contemporary challenges. Furthermore, global navigation satellite systems (GNSS) are now responding to challenges posed by climate change by unravelling the impacts of teleconnection (e.g., ENSO) as well as advancing the use of reflected signals (GNSS-reflectometry) to monitor, e.g., soil moisture variations. Indeed all these rely on the explosive use of “big data” in many fields of human endeavour. Moreover, with the ever-increasing global population, intense pressure is being exerted on the Earth’s resources, leading to significant changes in its land cover (e.g., deforestation), diminishing biodiversity and natural habitats, dwindling fresh water supplies, and changing weather and climatic patterns (e.g., global warming, changing sea level). Environmental monitoring techniques that provide information on these are under scrutiny from an increasingly environmentally conscious society that demands the efficient delivery of such information at a minimal cost. Environmental changes vary both spatially and temporally, thereby putting pressure on traditional methods of data acquisition, some of which are highly labour intensive, such as animal tracking for conservation purposes. With these challenges, conventional monitoring techniques, particularly those that record spatial changes call for more sophisticated approaches that deliver the necessary information at an affordable cost. One direction being pursued in the development of such techniques involves environmental geoinformatics, which can act as a stand-alone method or complement traditional methods.
