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Author : Didier Berthelot
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (594 download)
Download or read book Synthesis of Novel Heterocyclic Alpha-amino Acids written by Didier Berthelot and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author : D. Berthelot
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (776 download)
Download or read book Synthesis of Novel Heterocyclic [alpha]-amino Acids written by D. Berthelot and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Didier Berthelot
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (11 download)
Download or read book Synthesis of Novel Heterocyclic Α-amino Acids written by Didier Berthelot and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Novel Heterocyclic [alpha]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/D5MiMwEACAAJ?fife=w200-h370)
Author : D. Berthelot
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (776 download)
Download or read book Synthesis of Novel Heterocyclic [alpha]-amino Acids written by D. Berthelot and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. M. Williams
Publisher : Elsevier
ISBN 13 : 1483292959
Total Pages : 429 pages
Book Rating : 4.4/5 (832 download)
Download or read book Synthesis of Optically Active Alpha-Amino Acids written by R. M. Williams and published by Elsevier. This book was released on 2013-10-22 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.
Author : Zerong Wang
Publisher : CRC Press
ISBN 13 : 1000738922
Total Pages : 420 pages
Book Rating : 4.0/5 (7 download)
Download or read book Amino Acids: Insights and Roles in Heterocyclic Chemistry written by Zerong Wang and published by CRC Press. This book was released on 2023-05-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on α-amino acids, the potential challenges in working with α-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from alpha-amino acids. These heterocyclic compounds include hydantoins, thiohydantoins (including 2-thiohydantoins, 4-thiohydantoins, 2,4-dithiohydantoins), 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. This is the first resource to comprehensively collect all the heterocycles that can be directly prepared from α-amino acids. In addition, almost all kinds of synthetic methods for a particular type of heterocycles from alpha-amino acids are included, along with the detailed mechanistic discussions and experimental procedures. In Volume 2: Hydantoins, Thiohydantoins, and 2,5-Diketopiperazines compiles the three IUPAC accepted nomenclature systems for heterocyclic compounds, which will be very useful for readers working in the heterocyclic chemistry field for giving synthesized molecules their correct names. In addition, three groups of heterocyclic compounds, i.e., hydantoins, thiohydantoins (including 2-thiohydantoin, 4-thiohydantoin and 2,4-dithiohydantoin), and 2,5-diketopiperazines, have been organized with updated literature information. Particularly, all three groups of heterocyclic compounds have demonstrated many important biological activities, particularly anticancer and antibacterial activities. On the other hand, these three groups of heterocycles can be applied as substrates to make other chemical derivatives, particularly novel unnatural amino acids. All their reactivities have been compiled and updated. The other volumes include: Volume 1: Protecting Groups Volume 3: N-Carboxyanhydrides, N-Thiocarboxyanhydrides, and Sydnones Volume 4: Azlactones and Oxazolidin-5-ones All together, this unique 4-volume set thoroughly covers the two types of heterocyclic compounds that are originated from alpha-amino acids, providing carefully compiled updated information with detailed examples. The author has shared many thoughtful insights based on his strong background in physical organic chemistry. The volumes will be highly valuable for graduate students and senior students, as well as for professors and researchers working in the field of medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, and proteins and peptides.
Author : Michael Smith
Publisher : CRC Press
ISBN 13 : 9780824796044
Total Pages : 392 pages
Book Rating : 4.7/5 (96 download)
Download or read book Methods of Non-a-Amino Acid Synthesis written by Michael Smith and published by CRC Press. This book was released on 1995-05-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a comprehensive overview of, and the most common and useful methods for, the synthesis of non-alpha-amino acids, particularly amino acids that are key synthetic intermediates or important compounds in their own right. Attention is paid to acyclic amino acids C3-C10 including amino alkanoic carboxylic acids, aminoalkenoic acids and aminoalkynoic acids.
Author : Alexander Hugh Harkiss
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)
Download or read book Synthesis of Novel Fluorescent Heterocyclic-derived Α-amino Acids and the Total Syntheses of Piperidine Natural Products written by Alexander Hugh Harkiss and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Optically Active [alpha]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/khfwAAAAMAAJ?fife=w200-h370)
Author : Robert Michael Williams
Publisher : Pergamon
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)
Download or read book Synthesis of Optically Active [alpha]-amino Acids written by Robert Michael Williams and published by Pergamon. This book was released on 1989 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.
Author : Michael Bryant Smith
Publisher : CRC Press
ISBN 13 : 1466577894
Total Pages : 244 pages
Book Rating : 4.4/5 (665 download)
Download or read book Methods of Non-α-Amino Acid Synthesis, Second Edition written by Michael Bryant Smith and published by CRC Press. This book was released on 2013-10-23 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although less common than α-amino acids, non-α-amino acids—where the amino group is not on the carbon immediately adjacent to the carboxyl group but is attached to another carbon in the chain (for example, the β, γ, δ carbon)—are components of biologically important molecules, are significant in the pharmaceutical industry, and are useful starting materials for many areas of organic chemistry. Since the publication of the first edition of this book nearly 20 years ago, synthetic work devoted to the preparation of non- α-amino acids has expanded greatly. Methods of Non-α-Amino Acid Synthesis, Second Edition has been extensively rewritten and reorganized, providing an up-to-date review of strategies and methods for non-α-amino acid synthesis, particularly those amino acids that are key synthetic intermediates or important compounds in their own right. It focuses on acyclic amino acids of C3–C10, but also aminoalkanoic carboxylic acids, aminoalkenoic acids, and aminoalkynoic acids. The new edition contains many updated references and has a greater emphasis on the biological importance of non-α-amino acids. In addition to an array of synthetic methods, the book offers discussions on why non-α-amino acids are important. The book covers synthetic methods that rely on substituent refunctionalization, the conversion of cyclic precursors to acyclic amino acids, conjugate addition reactions, and enolate anion reactions and condensation reactions that lead to non-α-amino acids. It also examines reactions and strategies that lead to good diastereoselectivity and enantioselectivity during synthesis. A chapter devoted to biologically important amino acids includes separate sections on GABA, GABOB, carnitine, DAVA, statine, and other significant amino acids as well as a new section on peptides and proteins that contain non-α-amino acids. The final chapter addresses aminocyclic and heterocyclic amino acids.
Author : Robert Adam Mosey
Publisher :
ISBN 13 :
Total Pages : 468 pages
Book Rating : 4.3/5 (129 download)
Download or read book Synthesis of Novel Quaternary Alpha-amino Acids and 2-imidazolines Derived from Oxazol-5(4H)-ones and Evaluation of Their Proteasoman Inhibition Activity written by Robert Adam Mosey and published by . This book was released on 2010 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Novel [alpha]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/TA2toAEACAAJ?fife=w200-h370)
Author : Irene Warden
Publisher :
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.:/5 (882 download)
Download or read book Synthesis of Novel [alpha]-amino Acids written by Irene Warden and published by . This book was released on 1990 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Zerong Wang
Publisher : CRC Press
ISBN 13 : 1000738876
Total Pages : 433 pages
Book Rating : 4.0/5 (7 download)
Download or read book Amino Acids: Insights and Roles in Heterocyclic Chemistry written by Zerong Wang and published by CRC Press. This book was released on 2023-05-26 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on α-amino acids, the potential challenges in working with α-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from α-amino acids. These heterocyclic compounds include hydantoins, thiohydantoins (including 2-thiohydantoins, 4-thiohydantoins, 2,4-dithiohydantoins), 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. This is the first resource to comprehensively collect all the heterocycles that can be directly prepared from α-amino acids. In addition, almost all kinds of synthetic methods for a particular type of heterocycles from α-amino acids are included, along with the detailed mechanistic discussions and experimental procedures. Volume 1: Protecting Groups collects and discusses the 260 protecting groups relating to amino acids, which have been organized by carboxyl group, amino group, and side chain group. The conditions to introduce these protecting groups as well as their deprotecting procedures have also been incorporated, along with the physical properties, solvent effects, and temperature effects on the solubility of amino acids. It presents the solubility of glycine and phenylalanine in a variety of solvent systems to show the impact on amino acid, where glycine generally represents the polar amino acid whereas phenylalanine represents the amino acid of non-polar side chain. The other volumes include: Volume 2: Hydantoins, Thiohydantoins, and 2,5-Diketopiperazines Volume 3: N-Carboxyanhydrides, N-Thiocarboxyanhydrides, and Sydnones Volume 4: Azlactones and Oxazolidin-5-ones All together, this unique 4-volume set thoroughly covers the two types of heterocyclic compounds that are originated from alpha-amino acids, providing carefully compiled updated information with detailed examples. The author has shared many thoughtful insights based on his strong background in physical organic chemistry. The volumes will be highly valuable for graduate students and senior students, as well as for professors and researchers working in the field of medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, and proteins and peptides.
![Download Synthesis of Novel Trifluoroethylated [alpha]-amino Acids and Peptides PDF Online Free](https://books.google.com/books/content/images/frontcover/OXNyNwAACAAJ?fife=w200-h370)
Author : Changqing Lu
Publisher :
ISBN 13 :
Total Pages : 594 pages
Book Rating : 4.:/5 (72 download)
Download or read book Synthesis of Novel Trifluoroethylated [alpha]-amino Acids and Peptides written by Changqing Lu and published by . This book was released on 2005 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Synthesis of Unnatural Enone-containing [alpha]-amino Acids PDF Online Free](https://books.google.com/books/content/images/frontcover/tKmgAQAACAAJ?fife=w200-h370)
Author : Lindsay S. Fowler
Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.:/5 (784 download)
Download or read book Synthesis of Unnatural Enone-containing [alpha]-amino Acids written by Lindsay S. Fowler and published by . This book was released on 2011 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fast and efficient synthetic route was developed for the synthesis of a novel class of enone-containing alpha-amino acid. An amino acid-derived beta-ketophosphonate ester was subjected to Horner-Wadsworth-Emmons conditions using a variety of aldehydes to produce a diverse library of alpha, beta-unsaturated amino acids. E-Configured enone-containing amino acids were also deprotected using a two-stage approach to give the parent alpha-amino acids. A minor modification to the route enabled the synthesis of Z-configured enones via the Still-Gennari reaction. A small library of Z-enones was produced using various aldehydes. Enone-functionalised alpha-amino acids were employed as substrates for an intramolecular cyclisation reaction to generate 6-substituted-4-oxopipecolic acids. A diastereoselective one-pot reductive amination/cyclisation strategy was developed to gain access to the anti-diastereomer of the chiral N-heterocycles. A small selection of 6-substituted-4-oxopipecolic acids was synthesised. 6-Substituted-4-oxopipecolic acids were also reduced diastereoselectively to generate 4- hydroxypipecolic acid analogues.
Author : Thomas Scott Yokum
Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.:/5 (391 download)
Download or read book Synthesis of Novel Amino Acids and 310- and Alpha-helical Alpha, Alpha-disubstituted Amino Acid Rich Antimicrobial Peptides written by Thomas Scott Yokum and published by . This book was released on 1998 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mala Mistry
Publisher :
ISBN 13 :
Total Pages : 398 pages
Book Rating : 4.:/5 (592 download)
Download or read book Studies Towards the Synthesis of Novel Alpha-amino Acid Derivatives Using Dynamic Kinetic Resolution Methods written by Mala Mistry and published by . This book was released on 2003 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
