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Author : Alan J. Worsley
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)
Download or read book Synthesis of Bisbenzylisoquinoline Alkaloids with Potential Antimalarial Activity written by Alan J. Worsley and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alan J. Worsley
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Synthesis of Bisbenzylisoquinoline Alkaloids with Potential Antimalarialactivity written by Alan J. Worsley and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stephen Bennett
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (593 download)
Download or read book Synthesis of Bisbenzylisoquinoline Alkaloids as Novel Antimalarial Agents written by Stephen Bennett and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Da-Cheng Hao
Publisher : Academic Press
ISBN 13 : 0128142332
Total Pages : 406 pages
Book Rating : 4.1/5 (281 download)
Download or read book Ranunculales Medicinal Plants written by Da-Cheng Hao and published by Academic Press. This book was released on 2018-04-23 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy comprehensively covers this order of flowering plants, detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species, and between Chinese and non-Chinese species, is inferred through molecular phylogeny and based on nuclear and chloroplast DNA sequencing. The book discusses the conflict between chemotaxonomy and molecular phylogeny in the context of drug discovery and development. Users will find invaluable and holistic coverage on the study of Ranunculales that will make this the go-to pharmaceutical resource. - Describes current perceptions of biodiversity and chemodiversity of Ranunculales - Explains how the conceptual framework of plant pharmacophylogeny benefits the sustainable exploitation of Ranunculales - Details how Ranunculales medicinal plants work from the chemical level upward - Covers how the polypharmacology of Ranunculales compounds might inspire new chemical entity design and development for improved treatment outcomes
Author : Sabino Aurelio Bufo
Publisher : MDPI
ISBN 13 : 3039289276
Total Pages : 270 pages
Book Rating : 4.0/5 (392 download)
Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.
Author : A. Douglas Kinghorn
Publisher : Springer Nature
ISBN 13 : 3030898733
Total Pages : 116 pages
Book Rating : 4.0/5 (38 download)
Download or read book Antimalarial Natural Products written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2022-01-02 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
Author : Rosa Martha Pérez Gutiérrez
Publisher : Nova Publishers
ISBN 13 : 9781600213694
Total Pages : 666 pages
Book Rating : 4.2/5 (136 download)
Download or read book Handbook of Compounds with Cytotoxic Activity Isolated from Plants written by Rosa Martha Pérez Gutiérrez and published by Nova Publishers. This book was released on 2007 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: For thousands of years, plants show great importance in applications such as condiments, medicines, fragrances, colorants, ornaments, and thus through time scientific information has been obtained for botany, horticulture, chemistry and pharmacology. It is estimated that more than one billion dollars is spent in the commerce of medicinal plants and spices, and its study has greatly contributed to understand the physiological processes of photosynthesis and ecological relation of plants with the environment. Furthermore, plants continue to provide significant roles in traditional rituals of different societies. Presently, scientific research done by several institutions on natural products, have greatly contributed to the search for potential food and pharmacological products, and has greatly increased the interest of industry in the study of the methodology to explore the ecological, botanical, tissue culture, chemistry and pharmacological relation between plants, thus creating a great demand for professionals and specialists associated with botany, chemistry and pharmacology. For this reason, there is demand for more information about this knowledge, but there exists little scientific information that can provide a deep review of research in medicinal plants. This book presents 1752 compounds isolated and identified from plants that present anticancer activity. These substances have been classified by chemical groups and each provides the most relevant information of its pharmacological activity, action mechanism, chemical structure and other properties.
Author : Kelsey R. Downum
Publisher : Springer Science & Business Media
ISBN 13 : 1489917837
Total Pages : 301 pages
Book Rating : 4.4/5 (899 download)
Download or read book Phytochemical Potential of Tropical Plants written by Kelsey R. Downum and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the tropics, vast areas of rainforest and other biologically diverse lands are being cleared for agricultural or related uses. Rainforests, the most dramatic example of tropical habitat destrucLion, are estimated to be disappearing at the rate of up to 20.4 million hectares per year world-wide (based on FAO estimates; see World Resources 1990-1991, Oxford University Press) more than 2% of the total area covered by tropical rainforests per year. Destruction of these complex habitats results in the irreversible loss of both plant and animal diversity, and dramatically illustraLes the need to investigate these threatened species for potentially useful constituents-especially the identification and characterization of novel biologically-active phytochemicals with pharmacologiical and/or pesticidal properties. This volume is based on papers presented by invited speakers at an international symposium entitled "Phytochemical POlential of Tropical Plants: held in conjunction with the second joint meeting of the Phytochemical nd Societies of Europe and North America, as well as the 32 annual meeting of the latter society. The meeting was held at the Deauville Hotel, Miami Beach, Florida, USA from August 8-12,1992. One hundred and twenty-five participants from more than 20 countries attended this meeting.
Author :
Publisher :
ISBN 13 :
Total Pages : 1340 pages
Book Rating : 4.:/5 (31 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heinz Mehlhorn
Publisher : Springer Science & Business Media
ISBN 13 : 3642398243
Total Pages : 277 pages
Book Rating : 4.6/5 (423 download)
Download or read book Treatment of Human Parasitosis in Traditional Chinese Medicine written by Heinz Mehlhorn and published by Springer Science & Business Media. This book was released on 2013-09-30 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intensively examines the efficacy of plant-derived products that have been used for over a thousand years by practitioners of so-called Traditional Chinese Medicine in the light of recent chemotherapeuticals. The chapters were written by renowned Chinese medical researchers and are supplemented by results obtained in German antiparasitic research projects. Parasites and emerging diseases are a major threat of our time, which is characterized by an enormous increase in the size of the human population and by an unbelievably rapid globalization that has led to the daily transport of millions of humans and containers with goods from one end of the earth to the other. Furthermore the slow but constant global warming offers new opportunities for many agents of diseases to become established in new areas. Therefore it is essential that we develop precautions in order to avoid epidemics or even pandemics in overcrowded megacities or at the large-scale farm animal confinements that are needed to secure a steady flow of food in the crowded regions of the world. Of course intensive research in the field of chemotherapy since 1900 has produced unbelievable breakthroughs in therapies for formerly untreatable and thus deadly diseases. However, a large number of untreatable diseases remain, as well as a constantly growing number of agents of disease that have developed resistances to standard chemical compounds. As such, it is not only worthwhile but also vital to consider the enormous amounts of information that have been obtained by human “high cultures” in the past. Examples from the past (like quinine) or present (like artemisinin, a modern antimalarial drug) show that plant extracts may hold tremendous potential in the fight against parasites and/or against vector-transmitted agents of diseases.
Author : Christophe Wiart
Publisher : Academic Press
ISBN 13 : 0123983711
Total Pages : 430 pages
Book Rating : 4.1/5 (239 download)
Download or read book Lead Compounds from Medicinal Plants for the Treatment of Cancer written by Christophe Wiart and published by Academic Press. This book was released on 2012-10-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.
Author : Steven M. Colegate
Publisher : CRC Press
ISBN 13 : 1420006886
Total Pages : 624 pages
Book Rating : 4.4/5 (2 download)
Download or read book Bioactive Natural Products written by Steven M. Colegate and published by CRC Press. This book was released on 2007-12-14 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the
Author : Kishan Gopal Ramawat
Publisher : Springer
ISBN 13 : 9783642221439
Total Pages : 0 pages
Book Rating : 4.2/5 (214 download)
Download or read book Natural Products written by Kishan Gopal Ramawat and published by Springer. This book was released on 2013-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides a wealth of information regarding medicinal plants and phytochemicals. It is addressed both to researchers and teachers. The handbook describes phytochemicals, which, by the strictest definition, are chemicals that are produced by plants. During the last decades, more and more groups became actively involved in exploring plants for useful metabolites that lead to the identification of several useful curative agents and many promising molecules to fight and/or prevent diseases, including carcinogenesis and stroke. But when we talk about phytochemicals, there are also medicinal plants where not a single molecule is responsible for the observed properties. This reference work therefore reviews and compiles the information on both these aspects. The volumes contain contributions on phytochemicals and herbal extracts. A large number of natural products obtained from plants and microorganisms is used in cosmetic, drug, flavor and fragrance industries. For this compilation, a range of the most important medicinal herbs and phytochemicals were selected and are described by the recognized authors in the field. The present reference work encompasses the information about well established phytochemicals, biology and biotechnology of medicinal plants or their products, their biosynthesis, novel production strategies, demand and uses, metabolism and bioavailability. There is a surge of information published in recent years on herbal medicine and their pharmacologic effects with single books available on varied subjects. However, all this information is widespread and difficult to overview. Researchers who wish to keep a pace with the rapidly developing field of natural products can now consult this newly compiled handbook to find all information about bioactive molecules and medicinal plants thoroughly compiled in one place!
Author : Corrado Tringali
Publisher : CRC Press
ISBN 13 : 0203212312
Total Pages : 704 pages
Book Rating : 4.2/5 (32 download)
Download or read book Bioactive Compounds from Natural Sources written by Corrado Tringali and published by CRC Press. This book was released on 2003-09-02 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.
Author : Victor Kuete
Publisher : Newnes
ISBN 13 : 0124059368
Total Pages : 917 pages
Book Rating : 4.1/5 (24 download)
Download or read book Medicinal Plant Research in Africa written by Victor Kuete and published by Newnes. This book was released on 2013-06-19 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. - The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites - This book explores the essence of natural substances from African medicinal plants and their pharmacological potential - The authors are world reknowned African Scientists
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1681087251
Total Pages : 307 pages
Book Rating : 4.6/5 (81 download)
Download or read book Frontiers in Natural Product Chemistry written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2018-10-08 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. The fourth volume of the series brings seven reviews covering these topics: -natural antiamoebic medicines, analgesics and antimalarials -essential oils and cognitive performance -cannabis and drug development -lectins in biosensors -brassinosteroids
Author : Christophe Wiart
Publisher : Academic Press
ISBN 13 : 0123983835
Total Pages : 415 pages
Book Rating : 4.1/5 (239 download)
Download or read book Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases written by Christophe Wiart and published by Academic Press. This book was released on 2013-12-16 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development. - Incorporates compelling biological activity data and preclinical structure-activity relationships to help you choose promising lead molecules for further research - Includes primary source references to the most recent natural product discoveries in the field of neuroprotection in order to promote new drug discovery in this area - Contains detailed discussions of important neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease - Each plant section includes a critical evaluation of pharmacological, chemical, and toxicological evidence to support the use of the compound in drug discovery research in neurodegeneration
