Synthesis and Photophysics of Platinum(II) Terpyridyl Complexes

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Total Pages : 462 pages
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Book Synopsis Synthesis and Photophysics of Platinum(II) Terpyridyl Complexes by : Zhiqiang JI

Download or read book Synthesis and Photophysics of Platinum(II) Terpyridyl Complexes written by Zhiqiang JI and published by . This book was released on 2009 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design, Synthesis, Photophysics and Self-Assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-Responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest

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Publisher : Open Dissertation Press
ISBN 13 : 9781361368909
Total Pages : pages
Book Rating : 4.3/5 (689 download)

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Book Synopsis Design, Synthesis, Photophysics and Self-Assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-Responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest by : Yik-Sham Clive Chung

Download or read book Design, Synthesis, Photophysics and Self-Assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-Responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest written by Yik-Sham Clive Chung and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest" by Yik-sham, Clive, Chung, 鍾亦琛, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: A series of water-soluble platinum(II) terpyridine complexes with functionalized alkynyl ligands and a boronic acid-containing polymer, PAAPBA, have been synthesized and characterized. The photophysical and electrochemical properties of all the platinum(II) complexes have been studied. Some of the complexes have been demonstrated to show ground-state aggregation in organic solvents and aqueous solutions at high concentrations, leading to Pt...Pt and/or π-π interactions and hence the emergence of metal-metal-to-ligand charge transfer (MMLCT) transitions in both the UV-visible and emission spectra. The induced self-assembly of [Pt(tpy)(C≡CC6H4-CH2NMe3-4)](OTf)2 by PAAPBA has been explored for the development of glucose sensing protocols and α-glucosidase assay by monitoring the triplet metal-metal-to-ligand charge transfer (3MMLCT) emission in the near-infrared (NIR) region. [Pt(tpy){C≡CC6H4- {NHC(=NH2])(NH2)}-4}](OTf)2 has been observed to undergo induced aggregation in the presence of citrate, with good selectivity over other mono- and dicarboxylates in the tricarboxylic acid (TCA) cycle. Enzymatic activity of citrate lyase has also been probed by the emission spectral changes of the complex in the NIR region. A series of water-soluble alkynylplatinum(II) terpyridine complexes and water-soluble conjugated polyelectrolytes (CPEs) have been synthesized and characterized. The UV-vis absorption and emission properties of the platinum(II) complexes and CPEs have been investigated in organic solvents and/or aqueous buffer solutions. The electrochemical properties and ground-state aggregation at high concentrations of the platinum(II) complexes have also been examined. Two-component ensembles containing selected platinum(II) complexes and PPE-SO3- have been studied, and Forster resonance energy transfer (FRET) has been demonstrated from the PPE-SO3- donor to the aggregated complexes as acceptors. The ensemble containing PPE-SO3- and [Pt(tpy)(C≡CC6H4CH2NMe3-4)](OTf)2 has been employed for a "proof-of-principle" label-free detection of human serum albumin (HSA) in pH 3 buffer solutions with high selectivity and sensitivity, while another ensemble containing PPE-SO3- and [Pt{tpy(C6H4CH2NMe3-4)-4'}(C≡CC6H5)](OTf)2 has been utilized for selective label-free detection of G-quadruplex structure of the human telomeric DNA in physiological buffer solutions. A series of water-soluble platinum(II) terpyridine complexes with stimuli-responsive alkynyl ligands and a series of water-soluble platinum(II) metallosupramolecular triblock copolymers have been synthesized and characterized. The photophysical and electrochemical properties as well as the ground-state aggregation of the complexes have been investigated. Some of them have been found to show different electronic absorption and emission properties in aqueous solution at different pHs due to aggregation/deaggregation of the complexes. One of the complexes has been employed for live-cell imaging experiments to locate acidic organelles, such as lysosomes, in MDCK cells. The water-soluble platinum(II) metallosupramolecular triblock copolymers have been found to show an increase in 3MMLCT emission intensity in the red-NIR region with temperature, which has been attribu

Design and Synthesis of Luminescent Mono- And Dinuclear Platinum(ii) Alkynyl Terpyridine Complexes

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Publisher : Open Dissertation Press
ISBN 13 : 9781361426180
Total Pages : pages
Book Rating : 4.4/5 (261 download)

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Book Synopsis Design and Synthesis of Luminescent Mono- And Dinuclear Platinum(ii) Alkynyl Terpyridine Complexes by : Hoi-Yiu Chan

Download or read book Design and Synthesis of Luminescent Mono- And Dinuclear Platinum(ii) Alkynyl Terpyridine Complexes written by Hoi-Yiu Chan and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Design and Synthesis of Luminescent Mono- and Dinuclear Platinum(II) Alkynyl Terpyridine Complexes: From Photophysics to Aggregation and Self-assembly" by Hoi-yiu, Chan, 陳凱耀, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled DESIGN AND SYNTHESIS OF LUMINESCENT MONO- AND DINUCLEAR PLATINUM(II) ALKYNYL TERPYRIDINE COMPLEXES - FROM PHOTOPHYSICS TO AGGREGATION AND SELF-ASSEMBLY submitted by CHAN Hoi Yiu for the degree of Doctor of Philosophy at The University of Hong Kong in August 2006 A series of mononuclear alkynylplatinum(II) terpyridyl complexes, [Pt(trpy)({C{ C} C H )]PF, [Pt(trpy)({C{ C} C H CF -4)]PF, n 6 5 6 n 6 4 3 6 [Pt(trpy)({C{ C} C H CH -4)]PF, and [Pt( Bu trpy)(C{ C C{ C C H )]PF (n = n 6 4 3 6 3 6 5 6 2, 3), have been synthesized. The X-ray crystal structures of the two forms of [Pt(trpy)(C{ C C{ C C H )]PF, [Pt(trpy)(C{ C C{ C C{ C C H CH -4)]PF and 6 5 6 6 4 3 6 [Pt( Bu trpy)(C{ C C{ C C H )]PF have been determined. Dinuclear and 3 6 5 6 trinuclear alkynylplatinum(II) terpyridyl complexes, [1,4- {Pt(trpy)C{ C} C H ](OTf), [1,4-{Pt( Bu trpy)C{ C} C H ](OTf), [2,5- 2 6 4 2 3 2 6 4 2 {Pt(trpy)C{ C} C H S](OTf), [2,5-{Pt( Bu trpy)C{ C} C H S](OTf) and [1,3,5- 2 4 2 2 3 2 4 2 2 {Pt( Bu trpy)C{ C} C H ](OTf) have been successfully synthesized. The X-ray 3 3 6 3 3t crystal structure of [1,4-{Pt( Bu trpy)C{ C} C H ](OTf) has also been 3 2 6 4 2 determined. The luminescence properties of these complexes have been studied and their lowest-lying excited states in fluid solution and in the glass state were tentatively assigned as admixture of MLCT [dS (Pt)ĺ S *(trpy)] and LLCT [S (C{ C)ĺ S *(trpy)] origin, whereas the low-energy emissions in the solid state were attributed to triplet metal metal-to-ligand charge transfer ( MMLCT) phosphorescence, resulting from significant Pt---Pt interactions in the solid state. Besides, a series of luminescent platinum(II) terpyridyl alkynyl complexes with different counter anions, [Pt(trpy)(C{ C C{ C H)]X (X = OTf, PF, ClO, 6 4 BF, BPh ), [Pt(trpy)(C{ C C H )]X (X = OTf, PF, ClO, BF ) and 4 4 6 5 6 4 4 complexes with various substituents on the alkynyl and terpyridyl ligands, [Pt(trpy)(C{ CC H OCH-4)]OTf, [Pt(4'-CH O trpy)(C{ C C H )]OTf, 6 4 3 3 6 5 [Pt( Bu trpy)(C{ C C{ CH)]OTf, [Pt(trpy)(C{ CC H {CH NMe }-4)](OTf), 3 6 4 2 3 2 [Pt(trpy)(C{ C C{ C CH NMe )](OTf) and [Pt(trpy)(C{ C C{ C CH OH)]OTf 2 3 2 2 have been synthesized and their photophysical properties have been stuided. The X-ray crystal structure of [Pt(trpy)(C{ C C H )]ClO and 6 5 4 [Pt( Bu trpy)(C{ C C{ C H)]OTf have been determined. The solid-state absorption and emission spectra showed low-energy bands, which were assigned as derived from MMLCT origin. Solvent-induced aggregation studies of these complexes in solution showed that the color of the aggregates could be very different for different counter-ions, indicating that counter-ions played an important role in governing the degree of aggregation and the extent of interactions within these aggregates. Addition of various anions to solutions of [Pt(trpy)(C{ C C{ C H)]X (X = OTf, PF ) produced anion-induced color 6changes upon solvent-induced aggregation, showing that these complexes might serve as potential colorimetric anion probes. The effect of temperature on the aggregation properties of the complexes has also been explored. New low-energy absorption and emission bands were found upon a reduction of temperature, attributable to the formation o

Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest

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Total Pages : 0 pages
Book Rating : 4.:/5 (843 download)

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Book Synopsis Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest by : Yik-sham Chung (Clive)

Download or read book Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest written by Yik-sham Chung (Clive) and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest

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ISBN 13 :
Total Pages : 774 pages
Book Rating : 4.:/5 (843 download)

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Book Synopsis Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest by : Yik-sham Chung (Clive)

Download or read book Design, Synthesis, Photophysics and Self-assembly Study of Platinum (II) Terpyridine Complexes and Their Utilization as Stimuli-responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest written by Yik-sham Chung (Clive) and published by . This book was released on 2013 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthesis and Photophysics of Platinum(II) Terdentate and Bidentate Complexes

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ISBN 13 :
Total Pages : 218 pages
Book Rating : 4.:/5 (677 download)

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Book Synopsis Synthesis and Photophysics of Platinum(II) Terdentate and Bidentate Complexes by : Jing Yi

Download or read book Synthesis and Photophysics of Platinum(II) Terdentate and Bidentate Complexes written by Jing Yi and published by . This book was released on 2010 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design and Synthesis of Luminescent Mono- and Dinuclear Platinum(II) Alkynyl Terpyridine Complexes

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Total Pages : 0 pages
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Book Synopsis Design and Synthesis of Luminescent Mono- and Dinuclear Platinum(II) Alkynyl Terpyridine Complexes by : Hoi-yiu Chan

Download or read book Design and Synthesis of Luminescent Mono- and Dinuclear Platinum(II) Alkynyl Terpyridine Complexes written by Hoi-yiu Chan and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design and Synthesis of Luminescent Coumarin-Containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies

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Publisher : Open Dissertation Press
ISBN 13 : 9781361303887
Total Pages : pages
Book Rating : 4.3/5 (38 download)

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Book Synopsis Design and Synthesis of Luminescent Coumarin-Containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies by : Tsz-Chung Alvin Liu

Download or read book Design and Synthesis of Luminescent Coumarin-Containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies written by Tsz-Chung Alvin Liu and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Design and Synthesis of Luminescent Coumarin-containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies" by Tsz-chung, Alvin, Liu, 廖子衝, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4716835 Subjects: Platinum compounds - Synthesis Complex compounds - Synthesis Pyridine Alkynes

Synthesis, Structure, Photophysics, and Biological Activity of Platinum (II) Complexes

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ISBN 13 :
Total Pages : 291 pages
Book Rating : 4.:/5 (857 download)

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Book Synopsis Synthesis, Structure, Photophysics, and Biological Activity of Platinum (II) Complexes by : Dileep Atchyuth Kumar Vezzu

Download or read book Synthesis, Structure, Photophysics, and Biological Activity of Platinum (II) Complexes written by Dileep Atchyuth Kumar Vezzu and published by . This book was released on 2013 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis, structure, and photophysical properties of luminescent platinum (II) complexes with different coordination patterns, (C^C*N^N), (N^C*N), (N^N*C) and (N^N^C) are reported, where "C^N or N^N" denotes a bidentate coordination to the platinum to form a five-membered metallacycle and "C*N" denotes a bidentate coordination to the platinum to form a six-membered metallacycle. Sixteen cyclometalated platinum complexes have been synthesized with different coordination patterns, which include six complexes with tridentate N^C*N cyclometalating ligands (13, 14, 15, 16, 17, and 18), five complexes with N^N*C cyclometalating ligands (19a, 19b, 20a, 20b, and 24), three complexes with N^N^C cyclometalating ligands (21a, 21b, and 29) and two complexes with tetradentate C^C*N^N cyclometalating ligands (33 and 34). The structures of the platinum complexes 13, 15, 16, 18, 19a, 19b, 20a, 21a, 21b, 24, 29, 33, and 39 were determined by single crystal X-ray diffraction. In platinum complexes with five-six membered metallacycle (15, 16, 18, 19a, 19b, 20a, 24, and 39), the square geometry of the complexes is improved when compared to that of platinum complexes with five-five membered metallacycle as the biting angle is increased. The tetradentate coordination (C^C*N^N), square planar geometry of complex 33 are revealed from its X-ray crystal structure. The DFT calculations have been carried out on complexes 13, 14, 15, 16, 17, 18, 33, and 34 to examine the molecular orbital character of the complexes, which are used in interpreting the electronic spectra of the complexes. The photophysical properties of the platinum complexes were studied and a majority of the complexes were highly emissive in solution at room temperature. Complex 13 exhibited the highest quantum yield (65%) among all of the complexes. Self quenching was not observed in a majority of the platinum complexes at lower concentrations. The cytotoxicity (IC50) of the complexes in three lung cancerous cell lines and one prostate cancer cell line were determined by MTT assay. The toxic platinum complexes induced the cell death by triggering apoptosis. The interactions of the platinum complexes with plasmid and calf thymus DNA were studied. Activation of caspase -7, PARP, and p53 were also observed in RV1 and HCC827 cell lines when treated with platinum complexes. Complexes 35, 37 and 38 were more potent than the clinically approved drug, cis-platin.

Synthesis and Photophysics of Liquid-crystalline Complexes of Gold(III) and Platinum(IV).

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Total Pages : pages
Book Rating : 4.:/5 (119 download)

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Book Synopsis Synthesis and Photophysics of Liquid-crystalline Complexes of Gold(III) and Platinum(IV). by : Rachel Parker

Download or read book Synthesis and Photophysics of Liquid-crystalline Complexes of Gold(III) and Platinum(IV). written by Rachel Parker and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

SYNTHESES PHOTOPHYSICS & PHOTO

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Publisher : Open Dissertation Press
ISBN 13 : 9781374762886
Total Pages : 308 pages
Book Rating : 4.7/5 (628 download)

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Book Synopsis SYNTHESES PHOTOPHYSICS & PHOTO by : 楊覺茵

Download or read book SYNTHESES PHOTOPHYSICS & PHOTO written by 楊覺茵 and published by Open Dissertation Press. This book was released on 2017-01-27 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Syntheses, Photophysics and Photochemistry of Alkynyl-, Sulfido- and Selenido- Platinum(II) Complexes" by 楊覺茵, Kok-yan, Yeung, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b3123638 Subjects: Platinum - Synthesis Photochemistry Ligands Nuclear magnetic resonance spectroscopy

Design and Synthesis of Luminescent Coumarin-containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies

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ISBN 13 :
Total Pages : 165 pages
Book Rating : 4.:/5 (783 download)

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Book Synopsis Design and Synthesis of Luminescent Coumarin-containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies by : Tsz-chung Liu (Alvin)

Download or read book Design and Synthesis of Luminescent Coumarin-containing Platinum (II) Terpyridine Alkynyl Complexes and Their Spectroscopic, Photophysical and Binding Studies written by Tsz-chung Liu (Alvin) and published by . This book was released on 2011 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design, Synthesis and Photophysical Properties of Dinuclear Platinum (II) Complexes with Varying Bridging and Cyclometalating Ligands

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ISBN 13 :
Total Pages : 189 pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Design, Synthesis and Photophysical Properties of Dinuclear Platinum (II) Complexes with Varying Bridging and Cyclometalating Ligands by : Subhangi Roy

Download or read book Design, Synthesis and Photophysical Properties of Dinuclear Platinum (II) Complexes with Varying Bridging and Cyclometalating Ligands written by Subhangi Roy and published by . This book was released on 2018 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents

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Publisher : Springer
ISBN 13 : 3662467186
Total Pages : 266 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents by : Kenneth Kam-Wing Lo

Download or read book Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents written by Kenneth Kam-Wing Lo and published by Springer. This book was released on 2015-06-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.

Design and Synthesis of Luminescent Metal Polypyridyl Complexes of Platinum(ii), Ruthenium(ii) and Osmium(ii) for Chemosensing and Biological Studies

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Publisher : Open Dissertation Press
ISBN 13 : 9781361428030
Total Pages : pages
Book Rating : 4.4/5 (28 download)

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Book Synopsis Design and Synthesis of Luminescent Metal Polypyridyl Complexes of Platinum(ii), Ruthenium(ii) and Osmium(ii) for Chemosensing and Biological Studies by : Wing-Suen Tang

Download or read book Design and Synthesis of Luminescent Metal Polypyridyl Complexes of Platinum(ii), Ruthenium(ii) and Osmium(ii) for Chemosensing and Biological Studies written by Wing-Suen Tang and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Design and Synthesis of Luminescent Metal Polypyridyl Complexes of Platinum(II), Ruthenium(II) and Osmium(II) for Chemosensing and Biological Studies" by Wing-suen, Tang, 鄧詠璇, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled DESIGN AND SYNTHESIS OF LUMINESCENT METAL POLYPYRIDYL COMPLEXES OF PLATINUM(II), RUTHENIUM(II) AND OSMIUM(II) FOR CHEMOSENSING AND BIOLOGICAL STUDIES Submitted by TANG WING SUEN for the degree of Doctor of Philosophy at The University of Hong Kong in November 2006 A series of platinum(II) terpyridyl alkynyl complexes derivatized with basic amino functionalities and crown ether pendants, [Pt(trpy)(C≡C-R)]X (R = - - -C H -N(CH ) -4, X = OTf; R = -C H -N(CH CH OCH ) -4, X = OTf; R = 6 4 3 2 6 4 2 2 3 2 - - -C H -NH-4, X = OTf; R = -C H -N(CH )-4, X = Cl; R = 6 4 2 6 4 3 2 - - -C H -N(CH CH OCH ) -4, X = Cl; R = -C H -NH -4, X = Cl; R = -B15C5, X 6 4 2 2 3 2 6 4 2 - - = OTf; R = -A15C5, X = OTf ) have been synthesized. The X-ray crystal structure of [Pt(trpy){C≡CC H -N(CH CH OCH )-4}](OTf) has been 6 4 2 2 3 2 determined. The lowest energy absorption of the complexes except [Pt(trpy)(C≡CB15C5)](OTf) were tentatively assigned to originate from a π(C≡C) → π*(trpy) ligand-to-ligand charge transfer (LLCT) transition mixed with some metal-to-ligand charge transfer (MLCT) contribution. The ion-binding and pH dependent properties have also been studied. Their photophysical and spectroscopic properties were shown to be dependent on pH and selected metal ions, and their colorimetric and luminescence chemosensing properties were described. Another series of platinum(II) terpyridyl alkynyl complexes, t - [Pt( Bu trpy)(C≡C-R)]X [R = -C H -NH -4, X = OTf; R = -C H -NCS-4, X = 3 6 4 2 6 4 - - - OTf; R =-C H -NHCOCH I-4, X = OTf; R = -UH-5 (UH = Uracil), X = Cl; 6 4 2 -UMe-5, X = OTf (UMe = 1,3-dimethyluracil)] have been successfully synthesized and characterized. The X-ray crystal structures of t t [Pt( Bu trpy)(C≡C-C H-NCS-4)](OTf), [Pt( Bu trpy)(C≡C-UH-5)]Cl and 3 6 4 3 [Pt( Bu trpy)(C≡C-UMe-5)](OTf) have been determined. Their photophysical and electrochemical behaviour, together with their protein labeling and DNA binding studies, have also been studied. The emission of the complexes in solution at room temperature has been tentatively assigned as originated from a dπ(Pt) → π*( Bu trpy) triplet MLCT excited state. The 77 K butyronitrile glass displayed dual luminescence which were assigned to originate from an intraligand (IL) phosphorescence of the terpyridine ligand and a dπ(Pt) → t 3 t π*( Bu trpy) MLCT phosphorescence. The [Pt( Bu trpy)(C≡C- 3 3 C H-NHCSNH-4)](OTf)-HSA and [Pt( Bu trpy)(C≡C-C H -NHCOCH S- 6 4 3 6 4 2 4)](OTf)-HSA (HSA = human serum albumin) bioconjugates were highly colored and exhibited luminescence in the visible region upon photoexcitation. A series of ruthenium(II) diimine complexes and an osmium(II) diimine complex containing extended π-conjugated ligands, [Ru(bpy) (pmra)](PF ) 2 6 2 [pmra = N-(2-pyridylmethylene)-2-fluorenamine], [Ru(bpy) (pmra)]Cl, 2 2 [Ru(bpy) (pmaa)]Cl [pmaa = N-(2-pyridylmethylene)-2-anthramine], 2 2 [Ru(bpy) (pmpa)]Cl [pmpa = N-(2-pyridylmethylene)-1-pyrenamine], 2 2 [Ru(bpy) (pmfa)]Cl [pmfa = N-(2-pyridylmethylene)-3-fluoranthenamine] 2 2 and [Os(bpy) (pmaa)](PF ), have been synthesized. The lowest energy 2 6 2 absorption bands of the ruthenium(II) complexes w

Design and Synthesis of Cyclometalated Platinum(II) Complexes

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Book Synopsis Design and Synthesis of Cyclometalated Platinum(II) Complexes by : 鄺家煒

Download or read book Design and Synthesis of Cyclometalated Platinum(II) Complexes written by 鄺家煒 and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design, Synthesis, Photophysics and Self-assembly Study of Platinum(II) 2,6-bis(benzimidazol-2'-yl)pyridine Complexes with Conjugated Polyelectrolytes and Their Utilization as Luminescent Probes for Molecules of Biological Interest

Download Design, Synthesis, Photophysics and Self-assembly Study of Platinum(II) 2,6-bis(benzimidazol-2'-yl)pyridine Complexes with Conjugated Polyelectrolytes and Their Utilization as Luminescent Probes for Molecules of Biological Interest PDF Online Free

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Total Pages : 478 pages
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Book Synopsis Design, Synthesis, Photophysics and Self-assembly Study of Platinum(II) 2,6-bis(benzimidazol-2'-yl)pyridine Complexes with Conjugated Polyelectrolytes and Their Utilization as Luminescent Probes for Molecules of Biological Interest by : 陳啟彥

Download or read book Design, Synthesis, Photophysics and Self-assembly Study of Platinum(II) 2,6-bis(benzimidazol-2'-yl)pyridine Complexes with Conjugated Polyelectrolytes and Their Utilization as Luminescent Probes for Molecules of Biological Interest written by 陳啟彥 and published by . This book was released on 2017 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: