Author : Marie Carmelle Serviane Pierre-Bolivar
Publisher :
ISBN 13 :
Total Pages : 139 pages
Book Rating : 4.:/5 (871 download)
Book Synopsis Synthesis and Characterization of Perm-selective SERS-active Silica-coated Gold Nanospheres for the Direct Detection of Small Molecules by : Marie Carmelle Serviane Pierre-Bolivar
Download or read book Synthesis and Characterization of Perm-selective SERS-active Silica-coated Gold Nanospheres for the Direct Detection of Small Molecules written by Marie Carmelle Serviane Pierre-Bolivar and published by . This book was released on 2013 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Above this value, however, uncontrolled nanoparticle aggregation occurred and large but irreproducible SERS signal intensities were monitored. Next, gold nanoparticles were encapsulated with varying silica shell thicknesses and purified using traditional centrifugation steps and/or column chromatography. Relative to the traditionally purified (i.e. centrifuged) samples, the SERS responses from small molecules using the column purified nanoparticle samples followed a well-known SERS distance-dependence model. Thus, surface chemistry cannot form more than a 2 nm thick layer on gold nanospheres if SERS applications were targeted. To overcome these challenges, gold nanospheres encapsulated with a thick silica shell were made SERS-active by etching the internal silica layer near the metal surface.