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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alain Carré
Publisher : CRC Press
ISBN 13 : 9004190783
Total Pages : 545 pages
Book Rating : 4.0/5 (41 download)
Download or read book Surface and Interfacial Aspects of Cell Adhesion written by Alain Carré and published by CRC Press. This book was released on 2011-01-19 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell adhesion comes into play in almost all domains of life. The range of situations in which it occurs, involving organisms, living tissues, microorganisms or single cells, is endless. Cell adhesion is involved in the binding of a cell to a surface, extracellular matrix, or another cell using cell adhesion molecules. It is crucial in the formation and maintenance of coherent multicellular structures. Cell surface adhesion molecules (integrins, for example) which transmit information from the extracellular matrix to the cell play vital roles in numerous cellular processes. Some of these include: cell growth, differentiation, embryogenesis, immune cell transmigration and response, and cancer metastasis. Also cell adhesion is involved in most of pathological situations. This book is divided into four parts as follows: Part 1: Fundamentals of Cell Adhesion; Part 2: Methods to Study Cell Adhesion; Part 3: Surface Treatments to Control Cell Adhesion and Behavior; and Part 4: Cell Adhesion in Medicine and Therapy. A bountiful information is covered in this book which represents the cumulative wisdom of many world-renowned researchers( physicists, materials scientists, chemists and biologists) engaged in unraveling the mechanisms of cell adhesion and how to mitigate or control it. It quite patent from the topics covered in this book that the subject of cell adhesion is truly interdisciplinary. This book should be of great interest and value to anyone interested in cell adhesion which is vitally important to human life.
Author : Jun-Lin Guan
Publisher : CRC Press
ISBN 13 : 9781420049435
Total Pages : 396 pages
Book Rating : 4.0/5 (494 download)
Download or read book Signaling Through Cell Adhesion Molecules written by Jun-Lin Guan and published by CRC Press. This book was released on 2019-04-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of signal transduction research is one of the fastest growing in all of biomedical research in recent years. Signaling through cell adhesion molecules have long been of interest because of their importance in embryonic development, homeostasis, immune responses, wound healing , and malignant transformation. However, it is only recently re
Author : D. Neil Granger
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041656
Total Pages : 99 pages
Book Rating : 4.6/5 (15 download)
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Author : Claudia Mierke
Publisher : Iph001
ISBN 13 : 9780750317511
Total Pages : 500 pages
Book Rating : 4.3/5 (175 download)
Download or read book Physics of Cancer written by Claudia Mierke and published by Iph001. This book was released on 2018-10-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
Author : Roland Kaunas
Publisher : CRC Press
ISBN 13 : 1466553820
Total Pages : 370 pages
Book Rating : 4.4/5 (665 download)
Download or read book Cell and Matrix Mechanics written by Roland Kaunas and published by CRC Press. This book was released on 2014-10-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores a Range of Multiscale Biomechanics/Mechanobiology ConceptsCell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forc
Author : Martin Hjortso
Publisher : CRC Press
ISBN 13 : 9780824789459
Total Pages : 300 pages
Book Rating : 4.7/5 (894 download)
Download or read book Cell Adhesion in Bioprocessing and Biotechnology written by Martin Hjortso and published by CRC Press. This book was released on 1994-10-20 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a detailed introduction to the fundamental phenomena that govern cell adhesion and describes bioengineering processes that employ cell adhesion, focusing on both biochemical and biomedical applications. All industrially relevant issues of cell adhesion - from basic concepts, quantitative experiments, and mathematical models to applications in bioreactors and other process equipment - are examined.
Author : Lewis Wolpert
Publisher : Oxford University Press
ISBN 13 : 0199601194
Total Pages : 153 pages
Book Rating : 4.1/5 (996 download)
Download or read book Developmental Biology: A Very Short Introduction written by Lewis Wolpert and published by Oxford University Press. This book was released on 2011-08-25 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.
Author : Pierre Bongrand
Publisher : Springer Science & Business Media
ISBN 13 : 366203008X
Total Pages : 253 pages
Book Rating : 4.6/5 (62 download)
Download or read book Studying Cell Adhesion written by Pierre Bongrand and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell adhesion - the attachment of cells to any surface such as other cell membranes or tissues - is a complex process. In many physiological and pathological processes adhesion of a cell is the first critical step. A wide spectrum of the most powerful techniques currently available to study the basic parameters of cell adhesion, including binding strength, binding efficiency, membrane-membrane or membrane-substrate interaction, structural properties and dynamics of cell surface molecules, is presented in this strategy book. Sophisticated quantitative approaches as well as comprehensible semi-quantitative methods are described. The detailed theoretical background allows the critical assessment and application of these techniques.
Author : Mario Barbosa
Publisher : Woodhead Publishing
ISBN 13 : 008100852X
Total Pages : 392 pages
Book Rating : 4.0/5 (81 download)
Download or read book Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair written by Mario Barbosa and published by Woodhead Publishing. This book was released on 2017-09-25 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. - Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration - Explores protein and peptides from the fundamentals, to processing and applications - Written by an international group of leading biomaterials researchers
Author : Manfred Schwab
Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)
Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Author : Motomu Shimaoka
Publisher : Humana Press
ISBN 13 : 9781617791659
Total Pages : 0 pages
Book Rating : 4.7/5 (916 download)
Download or read book Integrin and Cell Adhesion Molecules written by Motomu Shimaoka and published by Humana Press. This book was released on 2011-09-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrins play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, immune responses, wound healing, and regulation of cell growth and differentiation, but also in numerous pathological phenomena such as autoimmunity, thrombosis, and cancer metastasis/progression. Therefore, investigations on integrins often demand multi-disciplinary approaches, making researchers long for a handy collection of comprehensive and practical protocols that detail experimental methods for studying integrin and related cell adhesion molecule functionality. Integrin and Cell Adhesion Molecules: Methods and Protocols aims to provide readers not only with basic protocols in studying integrin functions, but also with summaries on those state-of-the-art technologies that have been utilized for understanding integrin functionality at the cellular, molecular, structural, and organismal levels. Divided into six convenient sections, this detailed volume covers basic protocols for the study of integrin and related cell adhesion molecule functionality in vitro, illustrates structural biology approaches for studying integrins and related cell adhesion molecules, focuses on emerging imaging technologies for investigating cell migration, presents strategies to elucidate signaling through cell adhesion molecules, includes experimental techniques to investigate integrin functions at organismal levels in a physiological context, and showcases the most promising methods and technologies for the development of novel therapeutics and diagnostics. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Both experts and non-experts in the scientific community who wish to study cell adhesion molecules and diagnostics will find Integrin and Cell Adhesion Molecules: Methods and Protocols authoritative, easily accessible, and vastly informative.
Author : Andrea Becchetti
Publisher : Springer
ISBN 13 : 9781461425830
Total Pages : 0 pages
Book Rating : 4.4/5 (258 download)
Download or read book Integrins and Ion Channels written by Andrea Becchetti and published by Springer. This book was released on 2012-05-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In other cases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel stimulation often controls integrin activation or expression. From a functional standpoint, studying the interplay between integrin receptors and ion channels clarifies how the extracellular matrix regulates processes as disparate as muscle excitability, synaptic plasticity and lymphocyte activation, just to mention a few. The derangement of these processes has many implications for pathogenesis processes, in particular for tumor invasiveness and some cardiovascular and neurologic diseases. This book provides a general introduction to the problems and methods of this blossoming field.
Author : Ulrike S. Stein
Publisher : Humana
ISBN 13 : 9781071613528
Total Pages : 348 pages
Book Rating : 4.6/5 (135 download)
Download or read book Metastasis written by Ulrike S. Stein and published by Humana. This book was released on 2022-04-03 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the most recent developments and methodologies on metastatic process, formation, and detection. Chapters guide readers through functional metastasis in vitro assays, non-mouse and mice metastasis models, methods for imaging metastasis, analyzing the tumor microenvironment, senescence and inflammation with respect to metastasis, methods to investgate the premetastatic/ metastatic, detecting biomarkers in patient, and bioinformatics to simulate the metastatic process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Metastasis: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.
Author : Seetharama D. Satyanarayanajois
Publisher : Humana Press
ISBN 13 : 9781617790119
Total Pages : 0 pages
Book Rating : 4.7/5 (91 download)
Download or read book Drug Design and Discovery written by Seetharama D. Satyanarayanajois and published by Humana Press. This book was released on 2011-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in the pharmaceutical sciences and medicinal chemistry has taken an important new direction in the past two decades with a focus on large molecules, especially peptides and proteins, as well as DNA therapeutics. In Drug Design and Discovery: Methods and Protocols, leading experts provide an in-depth view of key protocols that are commonly used in drug discovery laboratories. Covering both classic and cutting-edge techniques, this volume explores computational docking, quantitative structure-activity relationship (QSAR), peptide synthesis, labeling of peptides and proteins with fluorescent labels, DNA-microarray, zebrafish model for drug screening, and other analytical screening and biological assays that are routinely used during the drug discovery process. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and accessible, Drug Design and Discovery: Methods and Protocols serve as a vital laboratory reference for pharmaceutical chemists, medicinal chemists, and pharmacologists as well as for molecular biologists.
Author : J. S. Temenoff
Publisher : Pearson Prentice Hall
ISBN 13 : 9780132350440
Total Pages : 478 pages
Book Rating : 4.3/5 (54 download)
Download or read book Biomaterials written by J. S. Temenoff and published by Pearson Prentice Hall. This book was released on 2008 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use in an introductory course on biomaterials, taught primarily in departments of biomedical engineering. The book covers classes of materials commonly used in biomedical applications, followed by coverage of the biocompatibility of those materials with the biological environment. Finally, it covers some in-depth applications of biomaterials. It does all of this with an overall emphasis on tissue engineering.Co-authors, Johnna Temenoff and Antonios Mikos, are the 2010 Meriam/Wiley Distinguished Author Award Recipients for Biomaterials: The Intersection of Biology and Materials Science.
Author : Hugh Chisholm
Publisher :
ISBN 13 :
Total Pages : 1090 pages
Book Rating : 4.A/5 ( download)
Download or read book Encyclopaedia Britannica written by Hugh Chisholm and published by . This book was released on 1910 with total page 1090 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eleventh edition was developed during the encyclopaedia's transition from a British to an American publication. Some of its articles were written by the best-known scholars of the time and it is considered to be a landmark encyclopaedia for scholarship and literary style.
