Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel [beta]-lactam Antibiotics

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Book Synopsis Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel [beta]-lactam Antibiotics by : Simon Baker

Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel [beta]-lactam Antibiotics written by Simon Baker and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics

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Total Pages : 0 pages
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Book Synopsis Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics by : Simon Peter Baker

Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics written by Simon Peter Baker and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics

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Book Synopsis Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics by : Simon Peter Baker

Download or read book Studies Towards the Total Synthesis of BU-4794F and Alkene Metathesis in the Synthesis of Novel Β-lactam Antibiotics written by Simon Peter Baker and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel -lactam Antibiotics

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel -lactam Antibiotics by : Simon Baker

Download or read book Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel -lactam Antibiotics written by Simon Baker and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel {OCLCbr#DD}-lactam Antibiotics

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ISBN 13 :
Total Pages : 554 pages
Book Rating : 4.:/5 (94 download)

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Book Synopsis Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel {OCLCbr#DD}-lactam Antibiotics by :

Download or read book Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel {OCLCbr#DD}-lactam Antibiotics written by and published by . This book was released on 2000 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

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ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards by :

Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2001 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theses on any subject submitted by the academic libraries in the UK and Ireland.

Metathesis in Natural Product Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527642080
Total Pages : 413 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Metathesis in Natural Product Synthesis by : Janine Cossy

Download or read book Metathesis in Natural Product Synthesis written by Janine Cossy and published by John Wiley & Sons. This book was released on 2011-09-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this is a comprehensive view of a hot topic. Written by top international authors, this ready reference is clearly structured and packed with important information, including representative experimental procedures for practical applications. A real must-have for anyone working in natural product synthesis.

Synthesis of Macrocyclic Lactams Related to the Antitumor Antibiotic Geldanamycin by Ring Closing Metathesis

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Publisher :
ISBN 13 : 9783899630503
Total Pages : 270 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis Synthesis of Macrocyclic Lactams Related to the Antitumor Antibiotic Geldanamycin by Ring Closing Metathesis by : Aude Lemarchand

Download or read book Synthesis of Macrocyclic Lactams Related to the Antitumor Antibiotic Geldanamycin by Ring Closing Metathesis written by Aude Lemarchand and published by . This book was released on 2004 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biosynthesis of Antibiotics

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Publisher : Elsevier
ISBN 13 : 0323159192
Total Pages : 247 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Biosynthesis of Antibiotics by : J Snell

Download or read book Biosynthesis of Antibiotics written by J Snell and published by Elsevier. This book was released on 2012-12-02 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosynthesis of Antibiotics, Volume I focuses on research conducted on the properties, compositions, and chemical reactions of antibiotics. Composed of contributions of authors, the book discusses the microbial processes for the preparation of radioactive antibiotics. Areas of discussions include an introduction; microbial methods used in the preparation of radioactive antibiotics; and the presence of radioactive antibiotics prepared through microbial processes. The volume also focuses on the biosynthesis of penicillin and cephalosporins. Areas of interest include biosynthesis of penicillins; penicillin acylases; and cephalosporin C biosynthesis. The text also provides information on the biosynthesis of tetracycline antibiotics, streptomycin, and macrolide antibiotics. Numerical representations and schematic diagrams are presented to show the properties, compositions, and chemical reactions of antibiotics when exposed to varying conditions. This volume is a great source of data for workers, graduate students, and faculties of biological sciences in the conduct of academic and industrial research.

Total Synthesis of Natural Products with Antimicrobial Activity

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Publisher : Springer
ISBN 13 : 9811088063
Total Pages : 285 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Total Synthesis of Natural Products with Antimicrobial Activity by : Andrew Giltrap

Download or read book Total Synthesis of Natural Products with Antimicrobial Activity written by Andrew Giltrap and published by Springer. This book was released on 2018-05-02 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery. It describes the total synthesis of two classes of antimicrobial non-ribosomal peptides (NRPs) – teixobactin and the skyllamycins – with subsequent biological evaluation. The first part describes the first total synthesis of teixobactin by means of a solid-phase peptide synthesis-macrolactamisation approach, yielding a synthetic natural product that can combat a number of clinically relevant Gram-positive bacterial pathogens. The second part describes the first total synthesis of skyllamycins A-C, a family of structurally complex cyclic NRPs, which inhibit the growth of the Pseudomonas aeruginosa biofilms that are responsible for significant mortality among cystic fibrosis patients.

Studies Toward a Total Synthesis of Lactonamycin

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Studies Toward a Total Synthesis of Lactonamycin by : Lewis Preece

Download or read book Studies Toward a Total Synthesis of Lactonamycin written by Lewis Preece and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Work was undertaken towards the synthesis of the promising antibiotic lactonamycin (iii). Following the work of Parsons et al. it was proposed that cyclisation of the ene-diyne (i) would give access to advanced pentacyclic intermediate (ii) and that from this a total synthesis of lactonamycin would be achieved (scheme I). Scheme I : Proposed Parsons, Board, Waters cyclisation to form the pentacycle (iii)(For image refer to pdf). A synthesis towards the cyclisation precursor (i) was carried out and a route to the key tetrasubstituted phthalide (v) established. Further chemistry was proposed to complete the synthesis of lactonamycin (scheme II). Scheme II : Formation of a fully substituted benzolactone.(For image refer to pdf). During attempts to introduce the [beta]-bromoallyl group of key intermediate (v) using a high temperature Claisen rearrangement it was established that the benzodioxin (vii) underwent thermolysis to generate the reactive quinone methide intermediate (viii) and that in the presence of a nucleophilic solvent the adduct (ix) was formed (scheme III). Model studies showed the reaction to be both general and high-yielding. Scheme III : Novel quinone methide methodology. (For image refer to pdf).

Green Metathesis Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 9048134315
Total Pages : 432 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Green Metathesis Chemistry by : Valerian Dragutan

Download or read book Green Metathesis Chemistry written by Valerian Dragutan and published by Springer Science & Business Media. This book was released on 2009-10-26 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: An outstanding international scientific event in the field of metathesis chemistry, the NATO ASI "Green Metathesis Chemistry: Great Challenges in Synthesis, Catalysis and Nanotechnology" has been recently organized in Bucharest, Romania (July 21- August 2, 2008). Numerous renowned scientists, young researchers and students, convened for two weeks to present and debate on the newest trends in alkene metathesis and identify future perspectives in this fascinating area of organic, organometallic, catalysis and polymer chemistry with foreseen important applications in materials science and technology. Following the fruitful practice of NATO Advanced Study Institutes, selected contributions covering plenary lectures, short communications and posters have been compiled in this special volume dedicated to this successful convention on green metathesis chemistry. General interest was primarily focused on relevant "green chemistry" features related to all types of metathesis reactions (RCM, CM, enyne metathesis, ADMET and ROMP). Diverse opportunities for green and sustainable technologies and industrial procedures based on metahesis have been identified. Largely exemplified was the utility of this broadly applicable strategy in organic synthesis, for accessing natural products and pharmaceuticals, and also its ability to fit in the manufacture of smart and nanostructured materials, self-assemblies with nanoscale morphologies, macromolecular engineering.

Studies Towards the Synthesis of -Ebelactone-A And -Maurenone

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Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783848449583
Total Pages : 164 pages
Book Rating : 4.4/5 (495 download)

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Book Synopsis Studies Towards the Synthesis of -Ebelactone-A And -Maurenone by : Ravindar Kontham

Download or read book Studies Towards the Synthesis of -Ebelactone-A And -Maurenone written by Ravindar Kontham and published by LAP Lambert Academic Publishing. This book was released on 2012-03 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph features the studies directed towards the total synthesis of architecturally and biologically interesting polypropionate natural products (-)-Ebelactone-A and (-)-Maurenone utilizing desymmetrization as a key strategy. ( )-Ebelactone A, show structural characteristics in common with macrolide antibiotics. Ebelactones act as potent inhibitors of esterase s, lipases and N-formylmethionine amino peptidases, and they have shown to produce enhance immune responses. They are also reported to inhibit cutinases produced by fungal pathogens. Novel biological activity combined with unique and challenging structure of Ebelactone, made this compound an exciting target for the total synthesis. Secondly, this book described an efficient synthetic protocol for polypropionate natural product (-)-Maurenone, which was isolated by Faulkner et al. in 1986 from specimens of the pulmonate mollusc Siphonaria maura. This monograph is unique in dealing with many interesting synthetic protocols including full experimental procedures, analytical data for all synthetic materials and complete reference sections. This monograph can be served as a good hand book for synthetic organic chemists.

Handbook of Metathesis: Applications in organic synthesis

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ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Metathesis: Applications in organic synthesis by : Robert H. Grubbs

Download or read book Handbook of Metathesis: Applications in organic synthesis written by Robert H. Grubbs and published by . This book was released on 2003 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Directed Towards the Total Synthesis of Bryostatin

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ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.:/5 (26 download)

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Book Synopsis Studies Directed Towards the Total Synthesis of Bryostatin by : Erick Moran Carreira

Download or read book Studies Directed Towards the Total Synthesis of Bryostatin written by Erick Moran Carreira and published by . This book was released on 1990 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards the Total Synthesis of Lactonamycin

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (847 download)

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Book Synopsis Studies Towards the Total Synthesis of Lactonamycin by : Johnathan Board

Download or read book Studies Towards the Total Synthesis of Lactonamycin written by Johnathan Board and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthetic Studies Related to the Biosynthesis of the [beta]-lactam Antibiotics

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ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.:/5 (385 download)

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Book Synopsis Synthetic Studies Related to the Biosynthesis of the [beta]-lactam Antibiotics by : Stephen Robert Herchen

Download or read book Synthetic Studies Related to the Biosynthesis of the [beta]-lactam Antibiotics written by Stephen Robert Herchen and published by . This book was released on 1977 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: