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Studies Toward The Total Synthesis Of Eletefine
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Book Synopsis Studies Toward the Total Synthesis of Eletefine by : Ijaz Ahmed
Download or read book Studies Toward the Total Synthesis of Eletefine written by Ijaz Ahmed and published by . This book was released on 2010 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A method towards the total synthesis of eletefine is described. Two related convergent syntheses are explained which divide the molecule into two fragments. Improvements towards the synthesis of a bis-functionalized isoquinoline fragment are explained. Expansion on the knowledge and understanding of the isoquinoline system is also described. The synthesis illustrated entails a bromination of a triflate functionalized isoquinoline system and a regio-selective Sonogashira reaction. Suggestions towards the completion of the total synthesis are prescribed."--Abstract.
Book Synopsis Studies Toward the Total Synthesis of Eletefine by : Kyle William Rugg
Download or read book Studies Toward the Total Synthesis of Eletefine written by Kyle William Rugg and published by . This book was released on 2013 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Eletefine is a natural product of the stephaoxocane family of alkaloids. It possesses an isoquinoline moiety functionalized with three methoxy groups forming an electron rich aromatic system. Eletefine also possesses a ten-membered ring with a novel bridged vinyl ether functionality, and a remote chiral alcohol, making it a conspicuous and desirable target for the synthetic organic chemist. The plant from which eletefine was first isolated (Cissampelos glaberrima) has been used in traditional medicine for the relief of symptoms from urinary tract infections and asthma. The proposed synthesis of eletefine is a convergent route which features a Sonogashira coupling and a novel alkyne hydration. Herein, methods towards the synthesis of the model system des-hydroxyeletefine are described, in particular attempts towards formation of the AB ring system of des-hydroxyeletefine, as well as C8-C9 bond formation methodology via acylation and Sonogashira coupling."--Abstract.
Book Synopsis Studies Toward the Total Synthesis of (+)-etharvendiol by :
Download or read book Studies Toward the Total Synthesis of (+)-etharvendiol written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Toward the Total Synthesis of Ingenol by : LaToya I. Nevels
Download or read book Studies Toward the Total Synthesis of Ingenol written by LaToya I. Nevels and published by . This book was released on 2002 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Toward the Total Synthesis of Phyllaemblic Acid by : Tyrone Christopher Casey
Download or read book Studies Toward the Total Synthesis of Phyllaemblic Acid written by Tyrone Christopher Casey and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Phyllaemblic acid is a highly oxygenated natural product isolated along with a number of related compounds from the roots of Phyllanthis emblica L. by Zhang et al. in 2000. The roots of this shrub have been used by the people in south-east Asia as an antiscorbutic and in the treatment of diverse ailments, especially those associated with the digestive organs. A total synthesis has yet to be reported. A concise sequence has been developed which rapidly furnishes a range of meso bridged bicyclic ketones, in good yield and with complete diastereocontrol, utilizing on an [alpha],[alpha]'-annelation reaction of 1,3-dioxan-5-ones. The bicyclic systems are shown to adopt chair-boat conformations in both solution and in the solid state. Single diastereomers are obtained in two cases with two different substituents. Stereochemical outcomes have been rationalized using steric and stereoelectronic arguments. Carbon-carbon bond formation at the ketone carbonyl in these bicyclic systems is shown to be problematic. Ortho-acetal hydrolysis and diol reprotection as a bis-TBS ether provides a monocyclic system with increased ketone reactivity, allowing elaboration to an [alpha]-hydroxyaldehyde of appropriate stereochemistry for future application in a synthesis of the natural product. Preliminary studies towards this goal on a simplified model system are reported.
Book Synopsis Studies towards the total synthesis of FR182877 by : Frederick Woolf Goldberg
Download or read book Studies towards the total synthesis of FR182877 written by Frederick Woolf Goldberg and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Toward the Total Synthesis of Longifolene by : Rudolf Robert Bukownik
Download or read book Studies Directed Toward the Total Synthesis of Longifolene written by Rudolf Robert Bukownik and published by . This book was released on 1984 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Emindole DA by :
Download or read book Studies Towards the Total Synthesis of Emindole DA written by and published by . This book was released on 2003 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies towards the total synthesis of obtusallene IV by : Roshni Bhuva
Download or read book Studies towards the total synthesis of obtusallene IV written by Roshni Bhuva and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis Or Ouabain by : Grazia Piizzi, 1970-
Download or read book Studies Towards the Total Synthesis Or Ouabain written by Grazia Piizzi, 1970- and published by . This book was released on 2004 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Towards the Total Synthesis of Ingenol by : Hoon Bae
Download or read book Studies Directed Towards the Total Synthesis of Ingenol written by Hoon Bae and published by . This book was released on 2003 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Phyllaemblic Acid by : Michael Patrick Kyle
Download or read book Studies Towards the Total Synthesis of Phyllaemblic Acid written by Michael Patrick Kyle and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Towards the Total Synthesis of the Natural Products Avarol and Capentin by : Thomas Elliott Jacks
Download or read book Studies Directed Towards the Total Synthesis of the Natural Products Avarol and Capentin written by Thomas Elliott Jacks and published by . This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies in Natural Product Synthesis by : Irina Albrecht
Download or read book Studies in Natural Product Synthesis written by Irina Albrecht and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel -lactam Antibiotics by : Simon Baker
Download or read book Studies Towards the Total Synthesis of BU-479F and Alkene Metathesis in the Synthesis of Novel -lactam Antibiotics written by Simon Baker and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Total Synthesis of Neoliacinic Acid and Related Natural Products by : Carl Antony Baxter
Download or read book Studies Towards the Total Synthesis of Neoliacinic Acid and Related Natural Products written by Carl Antony Baxter and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Directed Toward the Total Synthesis of Longifolene by : Rudolf Robert Bukownik
Download or read book Studies Directed Toward the Total Synthesis of Longifolene written by Rudolf Robert Bukownik and published by . This book was released on 1984 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
