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Studies Toward The Synthesis Of Lomaiviticins A And B And Englerin A
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Book Synopsis Studies Toward the Synthesis of Lomaiviticins A and B and Englerin A by : Srinivas Achanta
Download or read book Studies Toward the Synthesis of Lomaiviticins A and B and Englerin A written by Srinivas Achanta and published by . This book was released on 2009 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part II: Studies toward the total synthesis of englerin A. Englerin A is a new guaiane sesquiterpene isolated recently in 2008. It has been shown to be a selective renal cancer inhibitor. We envisioned the synthesis of englerin A via a novel strategy featuring Wagner-Meerwein rearrangement followed by intramolecular cation trapping. This chapter describes the stereoselective synthesis of the key cis-decalin intermediate from ( - )-carvone and the unsuccessful attempts to realize the skeletal rearrangement.
Book Synopsis Synthetic Studies Toward the Total Synthesis of Lomaiviticin A and B by : Virginia Heather Sharron Grant
Download or read book Synthetic Studies Toward the Total Synthesis of Lomaiviticin A and B written by Virginia Heather Sharron Grant and published by . This book was released on 2006 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis N-Heterocyclic Carbenes in Organocatalysis by : Akkattu T. Biju
Download or read book N-Heterocyclic Carbenes in Organocatalysis written by Akkattu T. Biju and published by John Wiley & Sons. This book was released on 2019-01-07 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.
Book Synopsis Preparative Carbohydrate Chemistry by : Stephen Hanessian
Download or read book Preparative Carbohydrate Chemistry written by Stephen Hanessian and published by CRC Press. This book was released on 1997-01-02 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailing commonly used methods and procedures, this reference discusses the reactions and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the formation, cleavage, and reactions of derivatives and illustrates bond-forming reactions of SN2 types, free radicals, chain extensions, and branching. The contents include: sugar derivatives; selected reactions in carbohydrate chemistry; chemical synthesis of oligosaccharides and O-and N -glycosyl compounds; enzymatic synthesis of sialic acid, KDO, and related deoxyulosonic acids, and of oligosaccharides; synthesis of -glycosyl compounds; carbocycles from carbohydrates; and total synthesis of sugars from non-sugars. This authoritative reference offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. It also contains insightful chapter commentaries and succinct topic histories.
Book Synopsis Carbohydrate-based Drug Discovery by : Chi-Huey Wong
Download or read book Carbohydrate-based Drug Discovery written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates > Development of Carbohydrate-based Drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.
Book Synopsis Total Synthesis of Natural Products by : Jie Jack Li
Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Book Synopsis Organoselenium Chemistry by : Dennis Liotta
Download or read book Organoselenium Chemistry written by Dennis Liotta and published by Wiley-Interscience. This book was released on 1987-03-11 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selenium reactions; Selenocarbonyl compounds, etc..
Book Synopsis Carbohydrate Mimics by : Yves Chapleur
Download or read book Carbohydrate Mimics written by Yves Chapleur and published by Wiley-VCH. This book was released on 1998-09-10 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Mimics Concepts and Methods Edited by Yves Chapleur Apart from the various functions of carbohydrates in natural processes they are important building blocks for drugs, especially antibiotics. In addition, carbohydrates are considered as important structures in the immunological recognition process of the antigen-antibody reaction. The modification of the structure and thereby the chemistry of substrates is a common procedure in nature. This naturally occurring process is reflected in the concept of molecular mimicry, which has become a useful approach in drug discovery. The search for carbohydrate analogues that exhibit better binding activity, biological activity, and stability began with the synthesis of azasugars. A lot of structural modifications around the anomeric center of carbohydrates has been achieved over the last decade, and these are summarized in terms of the different chemical and biological aspects of carbohydrate mimics in one part of this book. In addition to the well established fields of C-glycosides, azasugars and carbasugars the other part of the book focusses on outstanding achievements in carbohydrate mimic research. Everybody who is active in carbohydrate research or is interested in moving into this exciting field will benefit from this up-to-date source of informations. The leading experts in this field describe their scientific approaches to real interdisciplinary puzzles. This book should be an inspiration to scientists in organic, medicinal chemistry, biochemistry, and biology.
Book Synopsis Drug Discovery from Nature by : S. Grabley
Download or read book Drug Discovery from Nature written by S. Grabley and published by Springer Science & Business Media. This book was released on 1998-11-26 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.
Book Synopsis Asymmetric Synthesis by : Mathias Christmann
Download or read book Asymmetric Synthesis written by Mathias Christmann and published by Wiley-VCH. This book was released on 2007-02-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A veritable "Who's who" of asymmetric synthesis introduces the reader to the leaders in the field with a four-page concentrate of their area of research along with a short biography. The book is organized into five chapters, each with an introductory preface. Starting from the key concepts of asymmetric synthesis diastereoselective methods, asymmetric catalysis) the Focus then shifts to its application to the synthesis natural products and industrial processes. Graduate students, academic and industrial researchers will find this book a rich source of inspiration for their own work as well as an indispensable tool for the preparation of seminars and exams. A must for everyone in the field.
Book Synopsis Combinatorial Chemistry by : Hicham Fenniri
Download or read book Combinatorial Chemistry written by Hicham Fenniri and published by Oxford University Press, USA. This book was released on 2000 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry and biology and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It also contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation. The use of automation and robotics is also explained. It is written at a level easily accessible to novices and will enable readers to use combinatorial techniques to the best advantage.
