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Author : Michael Nathan Dubowitz
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (535 download)
Download or read book Studies on the Genetics of Atopy and Atopic Asthma written by Michael Nathan Dubowitz and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael Damon Dubowitz
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.:/5 (452 download)
Download or read book Studies in the Genetics of Atopy and Atopic Asthma written by Michael Damon Dubowitz and published by . This book was released on 1998 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kian Fan Chung
Publisher : European Respiratory Society
ISBN 13 : 1849841047
Total Pages : 360 pages
Book Rating : 4.8/5 (498 download)
Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Author : William Osmond Charles Michael Cookson
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (612 download)
Download or read book The Genetics of Atopy and Atopic Asthma written by William Osmond Charles Michael Cookson and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : I. P. Hall
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetics of Asthma and Atopy written by I. P. Hall and published by S. Karger AG (Switzerland). This book was released on 1996 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergic disease is caused by exposure of genetically predisposed individuals to sensitizing agents. Presenting current reviews on the genetics of asthma and atopy, this volume aims to increase the understanding of the mechanisms underlying this predisposition. It includes general reviews on the role of genetic factors as well as articles specifically dealing with candidate genes or candidate loci likely to be important in the etiology of allergic disease. Other chapters deal with the genetics of airway responsiveness in animal models and work examining the linkage between HLA genotypes and allergic disease. Special attention is given to the role of genes on 11q (including the high affinity IgE receptor) in the development of allergic disease and the contribution of genes on 5q (including TH2 cytokine genes and the beta2-adrenoceptor gene) to the asthma phenotype. A compilation of exciting up-to-date information, this book is ideal for clinicians and basic scientists wishing to keep track of the latest findings in this challenging and fast-moving field.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309450314
Total Pages : 575 pages
Book Rating : 4.3/5 (94 download)
Download or read book Finding a Path to Safety in Food Allergy written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-27 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
Author : A. Barry Kay
Publisher : Wiley-Blackwell
ISBN 13 : 9780865428676
Total Pages : 1872 pages
Book Rating : 4.4/5 (286 download)
Download or read book Allergy and Allergic Diseases written by A. Barry Kay and published by Wiley-Blackwell. This book was released on 1997-07-14 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and up-to-date allergy textbook in the world. Over 100 chapters written by world leading authorities covering virtually every aspect of basic and clinical allergy fully illustrated throughout with numerous overview diagrams and many colour illustrations. Authors contributing are from UK, Europe, North America and Australia.
Author : Kenneth James Wysocki
Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.:/5 (752 download)
Download or read book Leukotriene Receptor Gene Variation and Atopic Asthma written by Kenneth James Wysocki and published by . This book was released on 2011 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atopic asthma is a complex disease process that has a significant social, personal and economic burden across all ages. Leukotriene-receptors are involved in the cascade of inflammation that may result in symptoms of atopy and asthma. Two leukotriene receptors have been identified in the lung. The cysteinyl leukotriene receptor 1 and cysteinyl leukotriene receptor 2 genes (i.e., CYSLTR1 and CYSLTR2) have been sequenced, and a number of single nucleotide polymorphisms (SNPs) within these genes have been identified. The purpose of this study was to: (1) Determine the relationship between CYSLTR1 genotypes, CYSLTR2 genotype, atopy, elevated IgE level, and eosinophilia, (2) Determine the relationship between CYSLTR1 genotypes, CYSLTR2 genotype, asthma, and atopic asthma, and (3) Determine the degree of interaction between CYSLTR2 genetic variation and gender in atopic asthma. Nested within two sub-studies of the Tucson Epidemiological Study of Airway Obstructive Disease (TESAOD) study, a prospective longitudinal cohort, 853 individuals were entered into this study. Study criteria included Non-Hispanic white adults, who consented to genetic testing in the two sub-studies. Tagging SNPs of the CYSLTR1 and CYSLTR2 genes were genotyped. Serum IgE status and eosinophilia were obtained from existing dataset. Questionnaires collected in the parent study were used to obtain demographic and clinical data. SNP rs321006 in the CYSLTR1 gene was associated with atopy among Non-Hispanic white women. Assuming a recessive model, among female Non-Hispanic white adults, the odds of having rs321073 CC genotype was 5.82 times higher among those with atopic asthma than those without atopic asthma. No gene by gender interaction was found between SNP of interest in CYSLTR2 and atopic asthma. Genetic association of SNPs rs321006 with atopy and rs321073 with atopic asthma are novel findings to date. Implications for nurses, clinicians, and scientists include better understanding of associations of these genetic variations with asthma, atopy, and atopic asthma that can generate further inquiry into other mechanisms of atopic asthma. These novel genetic associations with atopy and atopic asthma may have the potential for personalized medicine that might afford patients with appropriate treatment based on their genotype.
Author : Stephen T. Holgate
Publisher : Birkhäuser
ISBN 13 : 3034881371
Total Pages : 204 pages
Book Rating : 4.0/5 (348 download)
Download or read book The Hereditary Basis of Allergic Diseases written by Stephen T. Holgate and published by Birkhäuser. This book was released on 2012-12-06 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Luis Garcia-Marcos
Publisher : Frontiers Media SA
ISBN 13 : 2889455297
Total Pages : 152 pages
Book Rating : 4.8/5 (894 download)
Download or read book The Parallel March of Asthma and Allergy in Childhood: A Multi-Perspective Approach written by Luis Garcia-Marcos and published by Frontiers Media SA. This book was released on 2018-07-24 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has not been yet clarified whether allergy and asthma are part of the same condition or they follow a parallel path. This Research Topic aims to try and put some light in this parallel march going through crucial topics: from prenatal events to later risk factors such as obesity; and from basic immunology to immunotherapy, both subcutaneous and sublingual. We hope the readers can infer their own conclusions as what is first: egg or chicken.
Author : Dirkje S. Postma
Publisher : CRC Press
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetics of Asthma and Chronic Obstructive Pulmonary Disease written by Dirkje S. Postma and published by CRC Press. This book was released on 2007 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment. With contributions by an esteemed team of international authorities on the topic, this source spans the latest developments in the utilization of microarray techniques, linkage and association studies, mapping strategies, comparative genetics, microarray techniques, proteomics, and pharmacogenomics.
Author : S. G. O. Johansson
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805578105
Total Pages : 233 pages
Book Rating : 4.8/5 (55 download)
Download or read book Prevention of Allergy and Allergic Asthma written by S. G. O. Johansson and published by Karger Medical and Scientific Publishers. This book was released on 2004-01-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation In the western world, the prevalence of allergy and asthma has increased two- to threefold over the last 40 years and has reached epidemic proportions. This book represents the first complete document containing recommendations on the prevention of allergy and allergic asthma based on the current understanding of the immunological mechanisms of allergic reactions. Prevention of Allergy and Allergic Asthma was a collaborative project between the WAO (World Allergy Organization) and the WHO, launched in 1999. Following two interim reports, this monograph is the final report of the group of international experts involved in the project, ranging from basic immunologists to clinicians. Both theoretical and practical aspects are discussed, and constructive advice is given. Through its network of more than 70 member societies, the WAO will now promote the concept of prevention of allergies and allergic asthma worldwide to benefit patients prone to become allergic, to prevent the worsening of existing allergic diseases, and to reduce their high cost to society. This publication is recommended to specialists in allergy, pediatrics, pneumology and dermatology as well as to general practitioners, health care professionals, journalists, politicians and patients. Only by increasing the knowledge about allergic diseases throughout society can the right steps be taken for their effective prevention.
Author : Stephen B. Liggett
Publisher : Courier Corporation
ISBN 13 : 9780824797294
Total Pages : 632 pages
Book Rating : 4.7/5 (972 download)
Download or read book The Genetics of Asthma written by Stephen B. Liggett and published by Courier Corporation. This book was released on 1996-08-23 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date resource offers a comprehensive overview of the genetic bases of asthma - examining key pathways, animal models, molecular and genetic techniques, and human genetic studies and furnishing the latest results on genetic analyses involving atopy, human immunoglobulin E (IgE), bronchial hyperresponsiveness, and asthma. Discussing fundamental issues essential in the development of asthma, The Genetics of Asthma describes basic mechanisms that are altered by genetic factors...provides state-of-the-art concepts on the molecular basis of asthma...presents new insights based on traditional animal models and genetically altered mice...explains techniques for conducting genetic studies and statistical approaches for genetic analysis...supplies a critical assessment of issues associated with phenotyping...gives results of human studies on the genetics of asthma...and much more. With over 1900 bibliographic citations and more than 100 explanatory tables, drawings, and photographs, The Genetics of Asthma is an ideal reference for pulmonologists, clinical immunologists, and allergists, physiologists, geneticists, lung biologists, epidemiologists, biochemists, molecular biologists, internists, pediatricians, and graduate and medical school students in these disciplines.
Author : Brunello Wüthrich
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805566557
Total Pages : 223 pages
Book Rating : 4.8/5 (55 download)
Download or read book The Atopy Syndrome in the Third Millennium written by Brunello Wüthrich and published by Karger Medical and Scientific Publishers. This book was released on 1999-01-01 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the International Symposium 'The Atopy Syndrome in the Third Millennium' held in Zurich in October 1998. It focuses on IgE-mediated allergy, beginning from the first manifestation of atopy, atopic eczema in infancy, and leading to its manifestations in children, adolescents and adults, to hay fever, asthma and food allergy. The topics covered give an update and comprehensive review of the different atopic manifestations concerning clinic, diagnosis, pathomechanisms, treatment and prevention. Summarizing the current knowledge on the field of atopy this publication is essential reading for dermatologists, allergologists, otorhinolaryngologists, and pediatricians.
Author : Ruby Pawankar
Publisher : Springer Science & Business Media
ISBN 13 : 4431728023
Total Pages : 445 pages
Book Rating : 4.4/5 (317 download)
Download or read book Allergy Frontiers:Epigenetics, Allergens and Risk Factors written by Ruby Pawankar and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as “Exosomes, naturally occurring minimal antigen presenting units” and “Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.” The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic usually confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease.
Author :
Publisher : Springer
ISBN 13 : 9783030051464
Total Pages : 1001 pages
Book Rating : 4.0/5 (514 download)
Download or read book Allergy and Asthma written by and published by Springer. This book was released on 2019-06-25 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergy and Asthma: The Basics to Best Practices is intended to serve as a single comprehensive reference covering all needed knowledge of allergic diseases. Allergy is a unique and distinctive area of medicine wherein learning the fundamentals requires gathering information from various different disciplines. Allergic diseases affect various organ systems and the practice of a wide range of physicians from otolaryngologists, and pulmonologists, to gastroenterologists, dermatologists, and ophthalmologists. Clinicians and trainees alike will benefit from a resource that introduces the basic concepts, as well as providing comprehensive, consistently up-to-date instruction on intermediate and advanced conditions, research, and treatment strategies. The book is divided into nine sections and is written by some of the foremost experts in the field. Allergy and Asthma opens with an introduction which covers the epidemiology of allergic diseases, fundamentals of allergy and immunology, and a thorough grounding of different types of allergens. Early sections address allergic upper airway diseases, allergic skin diseases, and asthma in detail, using a structured, consistent format from chapter to chapter to provide continuity and ease of reference. Later sections thoroughly cover various food allergies, insect allergies, drug allergy, anaphylaxis, and utilize ample tables and illustrations to provide additional learning tools for the reader. This major reference not only provides basic knowledge on diagnosing and treating allergies, but moves beyond these basics to emphasize using a systematic approach to working up and treating a patient. A variety of techniques used in diagnosing asthma and allergy will be examined, of which include prick skin tests, in-vitro testing, patch testing and non-conventional allergy tests. Concluding this book are sections dedicated to management, therapeutic strategies of allergy and asthma, with a look to future research directions for this unique field. Physicians and residents in allergy and immunology, pulmonology, otolaryngology, gastroenterology, dermatology, ophthalmology and other specialties will find the work of value in enhancing their practice and studies. Researchers in a range of areas especially immunology and food science will also find this text to be a compelling and reliable resource.
