Studies On Simple Repetitive Dna Sequences

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Repetitive DNA Sequences

Author : Andrew G. Clark
Publisher : MDPI
ISBN 13 : 3039283669
Total Pages : 206 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Repetitive DNA Sequences by : Andrew G. Clark

Download or read book Repetitive DNA Sequences written by Andrew G. Clark and published by MDPI. This book was released on 2020-03-05 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the bulk of the genome. Repeats include transposable elements that can self-mobilize and disperse around the genome, and tandemly-repeated satellite DNAs that increase in copy number due to replication slippage and unequal crossing over. Despite their abundance, repetitive DNA is often ignored in genomic studies due to technical challenges in their identification, assembly, and quantification. New technologies and methods are now providing the unprecedented power to analyze repetitive DNAs across diverse taxa. Repetitive DNA is of particular interest because it can represent distinct modes of genome evolution. Some repetitive DNA forms essential genome structures, such as telomeres and centromeres, which are required for proper chromosome maintenance and segregation, whereas others form piRNA clusters that regulate transposable elements; thus, these elements are expected to evolve under purifying selection. In contrast, other repeats evolve selfishly and produce genetic conflicts with their host species that drive adaptive evolution of host defense systems. However, the majority of repeats likely accumulate in eukaryotes in the absence of selection due to mechanisms of transposition and unequal crossing over. Even these neutral repeats may indirectly influence genome evolution as they reach high abundance. In this Special Issue, the contributing authors explore these questions from a range of perspectives.

DNA Fingerprinting: State of the Science

Author : Sergio D. Pena
Publisher : Springer Science & Business Media
ISBN 13 : 9783764329068
Total Pages : 484 pages
Book Rating : 4.3/5 (29 download)

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Book Synopsis DNA Fingerprinting: State of the Science by : Sergio D. Pena

Download or read book DNA Fingerprinting: State of the Science written by Sergio D. Pena and published by Springer Science & Business Media. This book was released on 1993-07-01 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA fingerprinting had a well-defined birthday. In the March 7, 1985 issue of Nature, Alec Jeffreys and coworkers described the first develop ment ofmu1tilocus probes capable of simultaneously revealing hypervari ability at many loci in the human genome and called the procedure DNA fingerprinting. It was a royal birth in the best British tradition. In a few months the emerging technique had permitted the denouement of hith erto insoluble immigration and paternity disputes and was already heralded as a major revolution in forensic sciences. In the next year (October, 1986) DNA fingerprinting made a dramatic entree in criminal investigations with the Enderby murder case, whose story eventually was turned into a best-selling book ("The Blooding" by Joseph Wambaugh). Today DNA typing systems are routinely used in public and commercial forensic laboratories in at least 25 different countries and have replaced conventional protein markers as the methods of choice for solving paternity disputes and criminal cases. Moreover, DNA fingerprinting has emerged as a new domain of intense scientific activity, with myriad applications in just about every imaginable territory of life sciences. The Second International Conference on DNA Fingerprinting, which was held in Belo Horizonte, Brazil in November of 1992, was a clear proof of this.

Ancient DNA

Author : Bernd Herrmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461243181
Total Pages : 275 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Ancient DNA by : Bernd Herrmann

Download or read book Ancient DNA written by Bernd Herrmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ancient DNA refers to DNA which can be recovered and analyzed from clinical, museum, archaeological and paleontological specimens. Ancient DNA ranges in age from less than 100 years to tens of millions of years. The study of ancient DNA is a young field, but it has been revolutionized by the application of polymerase chain reaction technology, and interest is growing very rapidly. Fields as diverse as evolution, anthropology, medicine, agriculture, and even law enforcement have quickly found applications in the recovery of ancient DNA. This book contains contributions from many of the "first generation" researchers who pioneered the development and application of ancient DNA methods. Their chapters present the protocols and precautions which have resulted in the remarkable results obtained in recent years. The range of subjects reflects the wide diversity of applications that are emerging in research on ancient DNA, including the study of DNA to analyze kinship, recovery of DNA from organisms trapped in amber, ancient DNA from human remains preserved in a variety of locations and conditions, DNA recovered from herbarium and museum specimens, and DNA isolated from ancient plant seeds or compression fossils. Ancient DNA will serve as a valuable source of information, ideas, and protocols for anyone interested in this extraordinary field.

Repetitive DNA

Author : M.A. Garrido-Ramos
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021504
Total Pages : 239 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Repetitive DNA by : M.A. Garrido-Ramos

Download or read book Repetitive DNA written by M.A. Garrido-Ramos and published by Karger Medical and Scientific Publishers. This book was released on 2012-06-27 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the impact on genome structure, function and evolution.This publication is targeted at scientists and scholars at every level, from students to faculty members, and, indeed, anyone involved or interested in genetics, molecular evolution, molecular biology as well as genomics will find it a valuable source of up-to-date information.

Fish Cytogenetic Techniques

Author : Catherine Ozouf-Costaz
Publisher : CRC Press
ISBN 13 : 1482211998
Total Pages : 216 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Fish Cytogenetic Techniques by : Catherine Ozouf-Costaz

Download or read book Fish Cytogenetic Techniques written by Catherine Ozouf-Costaz and published by CRC Press. This book was released on 2015-06-17 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in fish cytogenetics have enhanced the interest in chromosome analysis in both fundamental (systematics and comparative genomics among fishes and other vertebrate groups) and applied (aquaculture, conservation and response to pollutants, whole genome sequencing of model fish species) research. Although the genomic material, the chro

Tandem Repeat Polymorphisms

Author : Anthony J. Hannan
Publisher : Springer Science & Business Media
ISBN 13 : 1461454344
Total Pages : 223 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Tandem Repeat Polymorphisms by : Anthony J. Hannan

Download or read book Tandem Repeat Polymorphisms written by Anthony J. Hannan and published by Springer Science & Business Media. This book was released on 2013-07-30 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.

Function and Evolution of Repeated DNA Sequences

Author : Guy-Franck Richard
Publisher : John Wiley & Sons
ISBN 13 : 1789451191
Total Pages : 404 pages
Book Rating : 4.7/5 (894 download)

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Book Synopsis Function and Evolution of Repeated DNA Sequences by : Guy-Franck Richard

Download or read book Function and Evolution of Repeated DNA Sequences written by Guy-Franck Richard and published by John Wiley & Sons. This book was released on 2024-02-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as "junk DNA"!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics.

Progress in Nucleic Acid Research and Molecular Biology

Author :
Publisher : Elsevier
ISBN 13 : 0080522645
Total Pages : 405 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Progress in Nucleic Acid Research and Molecular Biology by :

Download or read book Progress in Nucleic Acid Research and Molecular Biology written by and published by Elsevier. This book was released on 2000-10-19 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. - Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology - Features contributions from leaders in their fields - Contains abundant references

Introduction to Bioinformatics

Author : Stephen A. Krawetz
Publisher : Springer Science & Business Media
ISBN 13 : 1592593356
Total Pages : 720 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Introduction to Bioinformatics by : Stephen A. Krawetz

Download or read book Introduction to Bioinformatics written by Stephen A. Krawetz and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: to Bioinformatics A Theoretical and Practical Approach Edited by Stephen A. Krawetz, PhD Wayne State University School of Medicine, Detroit MI and David D. Womble, PhD Wayne State University School of Medicine, Detroit, MI ~ Springer Science+ ~ Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press !ne. in 2003 Softcover reprint of the hardcover 1 st edition 2003 humanapress.com Ali rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. Ali papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. G) ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials. Production Editor: Mark J. Breaugh. Cover design by Patricia F. Cleary and Paul A. Thiessen. Cover illustration by Paul A. Thiessen, chemicalgraphics.com.

Structural Biology and Functional Genomics

Author : E. Morton Bradbury
Publisher : Springer Science & Business Media
ISBN 13 : 9780792357810
Total Pages : 332 pages
Book Rating : 4.3/5 (578 download)

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Book Synopsis Structural Biology and Functional Genomics by : E. Morton Bradbury

Download or read book Structural Biology and Functional Genomics written by E. Morton Bradbury and published by Springer Science & Business Media. This book was released on 1999-08-31 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Dictionary of Genomics, Transcriptomics and Proteomics, 4 Volume Set

Author : Guenter Kahl
Publisher : John Wiley & Sons
ISBN 13 : 3527328521
Total Pages : 2744 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis The Dictionary of Genomics, Transcriptomics and Proteomics, 4 Volume Set by : Guenter Kahl

Download or read book The Dictionary of Genomics, Transcriptomics and Proteomics, 4 Volume Set written by Guenter Kahl and published by John Wiley & Sons. This book was released on 2015-06-08 with total page 2744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fifth edition and for the first time available as an electronic product with all entries cross-linked. This very successful long-seller has once again been thoroughly updated and greatly expanded. It now contains over 13,000 entries, and comprehensively covering genomics, transcriptomics, and proteomics. Each entry contains an extensive explanation, including a comprehensive listing of synonyms and acronyms, and all formulas have been redrawn to create a uniform style, while most of the figures are custom designed for this dictionary. The ultimate reference for all terms in the -omics fields.

DNA-targeting Molecules as Therapeutic Agents

Author : Michael J Waring
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014286
Total Pages : 432 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis DNA-targeting Molecules as Therapeutic Agents by : Michael J Waring

Download or read book DNA-targeting Molecules as Therapeutic Agents written by Michael J Waring and published by Royal Society of Chemistry. This book was released on 2018-03-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been remarkable advances towards discovering agents that exhibit selectivity and sequence-specificity for DNA, as well as understanding the interactions that underlie its propensity to bind molecules. This progress has important applications in many areas of biotechnology and medicine, notably in cancer treatment as well as in future gene targeting therapies. The editor and contributing authors are leaders in their fields and provide useful perspectives from diverse and interdisciplinary backgrounds on the current status of this broad area. The role played by chemistry is a unifying theme. Early chapters cover methodologies to evaluate DNA-interactive agents and then the book provides examples of DNA-interactive molecules and technologies in development as therapeutic agents. DNA-binding metal complexes, peptide and polyamide–DNA interactions, and gene targeting tools are some of the most compelling topics treated in depth. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.

The Conifers: Genomes, Variation and Evolution

Author : David B. Neale
Publisher : Springer
ISBN 13 : 3319468073
Total Pages : 593 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Conifers: Genomes, Variation and Evolution by : David B. Neale

Download or read book The Conifers: Genomes, Variation and Evolution written by David B. Neale and published by Springer. This book was released on 2019-03-23 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive volume on conifers detailing their genomes, variations, and evolution. The book begins with general information about conifers such as taxonomy, geography, reproduction, life history, and social and economic importance. Then topics discussed include the full genome sequence, complex traits, phenotypic and genetic variations, landscape genomics, and forest health and conservation. This book also synthesizes the research included to provide a bigger picture and suggest an evolutionary trajectory. As a large plant family, conifers are an important part of economic botany. The group includes the pines, spruces, firs, larches, yews, junipers, cedars, cypresses, and sequoias. Of the phylum Coniferophyta, conifers typically bear cones and evergreen leaves. Recently, there has been much data available in conifer genomics with the publication of several crop and non-crop genome sequences. In addition to their economic importance, conifers are an important habitat for humans and animals, especially in developing parts of the world. The application of genomics for improving the productivity of conifer crops holds great promise to help provide resources for the most needy in the world.

Research in Progress, FY 1992

Author : United States. Department of Energy. Office of Health and Environmental Research
Publisher :
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Research in Progress, FY 1992 by : United States. Department of Energy. Office of Health and Environmental Research

Download or read book Research in Progress, FY 1992 written by United States. Department of Energy. Office of Health and Environmental Research and published by . This book was released on 1993 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Author : Robert T. Gerlai
Publisher : Academic Press
ISBN 13 : 0128041161
Total Pages : 710 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai

Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts

Heterochromatin

Author : Ram Sagar Verma
Publisher : Cambridge University Press
ISBN 13 : 9780521334808
Total Pages : 324 pages
Book Rating : 4.3/5 (348 download)

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Book Synopsis Heterochromatin by : Ram Sagar Verma

Download or read book Heterochromatin written by Ram Sagar Verma and published by Cambridge University Press. This book was released on 1988-05-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The material included in Heterochromatin is impressively comprehensive and provides timely, authoritative information that would otherwise be difficult to obtain.' BioScience