Structure Of Bacterial Rna Polymerase Sigma Factors

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Cryo-EM Part A: Sample Preparation and Data Collection

Author :
Publisher : Academic Press
ISBN 13 : 0080956955
Total Pages : 466 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Cryo-EM Part A: Sample Preparation and Data Collection by :

Download or read book Cryo-EM Part A: Sample Preparation and Data Collection written by and published by Academic Press. This book was released on 2010-09-30 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cryo-EM Part A: Sample Preparation and Data Collection is dedicated to a description of the instruments, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the ideas, instrumentation, and methods underlying all cryo-EM approaches, which allow practitioners to easily move between them. Within each section, the articles are ordered according to the most common symmetry of the sample to which their methods are applied. - Includes time-tested core methods and new innovations applicable to any researcher - Methods included are useful to both established researchers and newcomers to the field - Relevant background and reference information given for procedures can be used as a guide

Diagnostic Molecular Biology

Author : Chang-Hui Shen
Publisher : Elsevier
ISBN 13 : 0323986099
Total Pages : 590 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Diagnostic Molecular Biology by : Chang-Hui Shen

Download or read book Diagnostic Molecular Biology written by Chang-Hui Shen and published by Elsevier. This book was released on 2023-06-29 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine. - Provides explanations on how techniques are used to diagnosis at the molecular level - Explains how to use information technology to communicate and assess results in the lab - Enhances our understanding of fundamental molecular biology and places techniques in context - Places protocols into context with practical applications - Includes extra chapters on respiratory viruses (Corona)

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Signal Transduction: Networks and Drug Targets

Author : Ryutaro Utsumi
Publisher : Springer Science & Business Media
ISBN 13 : 0387788859
Total Pages : 257 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Bacterial Signal Transduction: Networks and Drug Targets by : Ryutaro Utsumi

Download or read book Bacterial Signal Transduction: Networks and Drug Targets written by Ryutaro Utsumi and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.

Structure and Function of the Bacterial Genome

Author : Charles J. Dorman
Publisher : John Wiley & Sons
ISBN 13 : 1119308798
Total Pages : 437 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Structure and Function of the Bacterial Genome by : Charles J. Dorman

Download or read book Structure and Function of the Bacterial Genome written by Charles J. Dorman and published by John Wiley & Sons. This book was released on 2020-04-28 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.

Corynebacterium glutamicum

Author : Nami Tatsumi
Publisher : Springer Science & Business Media
ISBN 13 : 3642298575
Total Pages : 415 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Corynebacterium glutamicum by : Nami Tatsumi

Download or read book Corynebacterium glutamicum written by Nami Tatsumi and published by Springer Science & Business Media. This book was released on 2012-08-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.

Avoid Boring People

Author : James D. Watson
Publisher : Vintage
ISBN 13 : 0375727140
Total Pages : 370 pages
Book Rating : 4.3/5 (757 download)

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Book Synopsis Avoid Boring People by : James D. Watson

Download or read book Avoid Boring People written by James D. Watson and published by Vintage. This book was released on 2010-05-04 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Nobel Prize-winning scientist James D. Watson, a living legend for his work unlocking the structure of DNA, comes this candid and entertaining memoir, filled with practical advice for those starting out their academic careers. In Avoid Boring People, Watson lays down a life’s wisdom for getting ahead in a competitive world. Witty and uncompromisingly honest, he shares his thoughts on how young scientists should choose the projects that will shape their careers, the supreme importance of collegiality, and dealing with competitors within the same institution. It’s an irreverent romp through Watson’s colorful career and an indispensable guide to anyone interested in nurturing the life of the mind.

Strategies for Protein Purification and Characterization

Author : Daniel R. Marshak
Publisher :
ISBN 13 : 9780879694494
Total Pages : 420 pages
Book Rating : 4.6/5 (944 download)

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Book Synopsis Strategies for Protein Purification and Characterization by : Daniel R. Marshak

Download or read book Strategies for Protein Purification and Characterization written by Daniel R. Marshak and published by . This book was released on 1996 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Biological Chemistry

Author :
Publisher : Elsevier
ISBN 13 : 0128220406
Total Pages : 0 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Encyclopedia of Biological Chemistry by :

Download or read book Encyclopedia of Biological Chemistry written by and published by Elsevier. This book was released on 2021-07-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Biological Chemistry, Six Volume Set has always been characterized by its unique and comprehensive content. Since publication of the 2nd edition, many important discoveries have been made leading to novel concepts in several areas of biochemistry, and new technologies have advanced our understanding of key processes of life. All of these advances are included in the new and expanded third edition. With its 6 volumes, this is the most up-to-date and complete resource on biochemistry and molecular biology, provided through contributions by leading experts in the field. A ‘one-stop’, comprehensive resource on "the chemistry of life", including a wealth of information and critical summaries to support research and teaching activities Each chapter is written concisely to guide the reader though the topic, using a consistent and unified terminology Clearly organized into seven logical sections, each curated by a world-leader in the field and the Editor in Chief

Foodborne Pathogens

Author : Joshua B. Gurtler
Publisher : Springer
ISBN 13 : 3319568361
Total Pages : 653 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Foodborne Pathogens by : Joshua B. Gurtler

Download or read book Foodborne Pathogens written by Joshua B. Gurtler and published by Springer. This book was released on 2017-06-14 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne illnesses continue to be a major public health concern. All members of a particular bacterial genera (e.g., Salmonella, Campylobacter) or species (e.g., Listeria monocytogenes, Cronobacter sakazakii) are often treated by public health and regulatory agencies as being equally pathogenic; however, this is not necessarily true and is an overly conservative approach to ensuring the safety of foods. Even within species, virulence factors vary to the point that some isolates may be highly virulent, whereas others may rarely, if ever, cause disease in humans. Hence, many food safety scientists have concluded that a more appropriate characterization of bacterial isolates for public health purposes could be by virotyping, i.e., typing food-associated bacteria on the basis of their virulence factors. The book is divided into two sections. Section I, “Foodborne Pathogens and Virulence Factors,” hones in on specific virulence factors of foodborne pathogens and the role they play in regulatory requirements, recalls, and foodborne illness. The oft-held paradigm that all pathogenic strains are equally virulent is untrue. Thus, we will examine variability in virulence between strains such as Listeria, Salmonella, Campylobacter, Cronobacter, etc. This section also examines known factors capable of inducing greater virulence in foodborne pathogens. Section II, “Foodborne Pathogens, Host Susceptibility, and Infectious Dose” , covers the ability of a pathogen to invade a human host based on numerous extraneous factors relative to the host and the environment. Some of these factors include host age, immune status, genetic makeup, infectious dose, food composition and probiotics. Readers of this book will come away with a better understanding of foodborne bacterial pathogen virulence factors and pathogenicity, and host factors that predict the severity of disease in humans.

Nucleic Acid Polymerases

Author : Katsuhiko S. Murakami
Publisher : Springer Science & Business Media
ISBN 13 : 3642397964
Total Pages : 342 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Nucleic Acid Polymerases by : Katsuhiko S. Murakami

Download or read book Nucleic Acid Polymerases written by Katsuhiko S. Murakami and published by Springer Science & Business Media. This book was released on 2013-10-22 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans. Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.

RNA-Based Regulation in Human Health and Disease

Author :
Publisher : Academic Press
ISBN 13 : 0128171944
Total Pages : 446 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis RNA-Based Regulation in Human Health and Disease by :

Download or read book RNA-Based Regulation in Human Health and Disease written by and published by Academic Press. This book was released on 2020-08-19 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. - Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease - Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies - Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic - Features contributions from leading experts in the field

Cell Biology by the Numbers

Author : Ron Milo
Publisher : Garland Science
ISBN 13 : 1317230698
Total Pages : 400 pages
Book Rating : 4.3/5 (172 download)

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Book Synopsis Cell Biology by the Numbers by : Ron Milo

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Bacteriophage T4

Author : Christopher K. Mathews
Publisher :
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bacteriophage T4 by : Christopher K. Mathews

Download or read book Bacteriophage T4 written by Christopher K. Mathews and published by . This book was released on 1983 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guccione's Geriatric Physical Therapy E-Book

Author : Dale Avers
Publisher : Elsevier Health Sciences
ISBN 13 : 0323610153
Total Pages : 738 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Guccione's Geriatric Physical Therapy E-Book by : Dale Avers

Download or read book Guccione's Geriatric Physical Therapy E-Book written by Dale Avers and published by Elsevier Health Sciences. This book was released on 2019-10-24 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Physical Therapy** Offering a comprehensive look at physical therapy science and practice, Guccione's Geriatric Physical Therapy, 4th Edition is a perfect resource for both students and practitioners alike. Year after year, this text is recommended as the primary preparatory resource for the Geriatric Physical Therapy Specialization exam. And this new fourth edition only gets better. Content is thoroughly revised to keep you up to date on the latest geriatric physical therapy protocols and conditions. Five new chapters are added to this edition to help you learn how to better manage common orthopedic, cardiopulmonary, and neurologic conditions; become familiar with functional outcomes and assessments; and better understand the psychosocial aspects of aging. In all, you can rely on Guccione's Geriatric Physical Therapy to help you effectively care for today's aging patient population. - Comprehensive coverage of geriatric physical therapy prepares students and clinicians to provide thoughtful, evidence-based care for aging patients. - Combination of foundational knowledge and clinically relevant information provides a meaningful background in how to effectively manage geriatric disorders - Updated information reflects the most recent and relevant information on the Geriatric Clinical Specialty Exam. - Standard APTA terminology prepares students for terms they will hear in practice. - Expert authorship ensures all information is authoritative, current, and clinically accurate. - NEW! Thoroughly revised and updated content across all chapters keeps students up to date with the latest geriatric physical therapy protocols and conditions. - NEW! References located at the end of each chapter point students toward credible external sources for further information. - NEW! Treatment chapters guide students in managing common conditions in orthopedics, cardiopulmonary, and neurology. - NEW! Chapter on functional outcomes and assessment lists relevant scores for the most frequently used tests. - NEW! Chapter on psychosocial aspects of aging provides a well-rounded view of the social and mental conditions commonly affecting geriatric patients. - NEW! Chapter on frailty covers a wide variety of interventions to optimize treatment. - NEW! Enhanced eBook version is included with print purchase, allowing students to access all of the text, figures, and references from the book on a variety of devices.

Encyclopedia of Genetics

Author : Sydney Brenner
Publisher :
ISBN 13 :
Total Pages : 684 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedia of Genetics by : Sydney Brenner

Download or read book Encyclopedia of Genetics written by Sydney Brenner and published by . This book was released on 2002 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Encyclopedia of Genetics provides the most complete and authoritative coverage of genetics ever published. Dr. Sydney Brenner, the 2002 Nobel Prize winner for Physiology or Medicine, and Professor Jeffrey H. Miller of UCLA have gathered the world's top geneticists to contribute to this outstanding collection. Diverse information is compiled into a single, comprehensive source, containing a clear presentation of cutting-edge knowledge. Easy-to-use and well-organized, the Encyclopedia of Genetics is an invaluable reference work for everyone from the academic researcher to the educated layperson. The Encyclopedia provides: * Comprehensive coverage: at 4 volumes and over 1,700 entries this is the largest Genetics reference work currently available * Complete, up-to-date information * Initial online access to the online version, which includes fully searchable text and numerous hyperlinks to related sites * Cross-references to related articles within the Encyclopedia * 2800 pages; two-color printing throughout text and figures; color plate sections also included."--Provided by publisher

Biology for AP ® Courses

Author : Julianne Zedalis
Publisher :
ISBN 13 : 9781947172401
Total Pages : 1923 pages
Book Rating : 4.1/5 (724 download)

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Book Synopsis Biology for AP ® Courses by : Julianne Zedalis

Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.