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Author : Joseph D. Puglisi
Publisher :
ISBN 13 :
Total Pages : 189 pages
Book Rating : 4.:/5 (112 download)
Download or read book Structure Dynamics and Function of Biological Macromolecules and Assemblies written by Joseph D. Puglisi and published by . This book was released on 2005 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Maria Armenia Carrondo
Publisher : Springer
ISBN 13 : 9400725302
Total Pages : 213 pages
Book Rating : 4.4/5 (7 download)
Download or read book Macromolecular Crystallography written by Maria Armenia Carrondo and published by Springer. This book was released on 2011-12-01 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.
Author : Oleg Jardetzky
Publisher : IOS Press
ISBN 13 : 9781586030322
Total Pages : 212 pages
Book Rating : 4.0/5 (33 download)
Download or read book Dynamics, Structure, and Function of Biological Macromolecules written by Oleg Jardetzky and published by IOS Press. This book was released on 2001 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of articles looking at modern structural biology, summarizing the applications of physical methods - such as x-ray diffraction, high resolution nuclear magnetic resonance and molecular dynamics - to the study of protein structure and dynamics. There is a review of contemporary thoughts within the field, looking at the mechanisms of alloateric transitions and allosteric control, the transmission of information within protein structures and the role of dynamics in determining the specificity of protein - ligand interactions. There is also a look at future innovations.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joseph D. Puglisi
Publisher :
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.X/5 (4 download)
Download or read book Structure, Dynamics and Function of Biological Macromolecules and Assemblies written by Joseph D. Puglisi and published by . This book was released on 2005 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International School of Structural Biology and Magnetic Resonance, held at Erice, Italy, in 2003.
Author : Anders Ehrenberg
Publisher : Springer Science & Business Media
ISBN 13 : 3642717055
Total Pages : 316 pages
Book Rating : 4.6/5 (427 download)
Download or read book Structure, Dynamics and Function of Biomolecules written by Anders Ehrenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a collection of papers presented and discussed at the first EBSA workshop held at Saltsj6baden outside stockholm in Sweden, July 6-10, 1986. The common theme of these papers is dynamics of biomolecules, and how the dynamics depends on the molecular structure and organi zation, and connects to and determines the biological function. This is a rapidly expanding field of research which combines many different aspects of molecular bio physics. Much material is new and presented for the first time. Even if the work so far has been of the kind that is usually called basic research, practical applications are clearly indicated in some articles, and are waiting around the corner in several other cases. At the workshop only one third of the time was used for the formal presentations and two thirds for discussion. To this should also be added discussions during the poster sessions. During these lively and unrecorded discussions fresh viewpoints emerged and new ideas were created. Ad mittedly, our knowledge at present is only fragmentary but when pieces of the puzzle are brought together at a workshop or in a publication of this kind more extended and sometimes unexpected contours and shapes become vi sible. It is our hope that this rapid publication of camera-ready manuscripts will transfer some of the spi rit at the workshop to the reader, and in his or her institute or laboratory initiate further discussions, bring forward more ideas and start new experimental ap roaches.
Author : Miriam Balaban
Publisher :
ISBN 13 :
Total Pages : 516 pages
Book Rating : 4.F/5 ( download)
Download or read book Structural Aspects of Recognition and Assembly in Biological Macromolecules: Proteins and protein complexes ; Fibrous proteins written by Miriam Balaban and published by . This book was released on 1981 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alasdair Steven
Publisher : Garland Science
ISBN 13 : 1134982828
Total Pages : 1396 pages
Book Rating : 4.1/5 (349 download)
Download or read book Molecular Biology of Assemblies and Machines written by Alasdair Steven and published by Garland Science. This book was released on 2016-02-18 with total page 1396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of Assemblies and Machines provides a comprehensive narrative of the ways in which macromolecular structures assemble and how they interact with other complexes and organelles in the cell. Richly illustrated in full color, the text is written for advanced undergraduates, graduate students, and researchers in biochemistry, molecular biology, biophysics, cell biology, chemistry, structural biology, immunology, microbiology, and medicine.
Author : Oleg Jardetzky
Publisher : Springer Science & Business Media
ISBN 13 : 1461558395
Total Pages : 308 pages
Book Rating : 4.4/5 (615 download)
Download or read book Dynamics and the Problem of Recognition in Biological Macromolecules written by Oleg Jardetzky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organize themselves into organs by recognizing each other through macromolecular surface-specific interactions. These recognition processes involve the mu tual adaptation of structures that rely on their flexibility. All sorts of conformational changes occur in proteins involved in through-membrane signal transmission, showing another aspect of the flexibility of these macromolecules. The movement and flexibility are inscribed in the polymeric nature of essential biological macromolecules such as proteins and nucleic acids. For instance, the well-defined structures formed by the long protein chain are held together by weak noncovalent interac tions that design a complex potential well in which the protein floats, permanently fluctuating between several micro- or macroconformations in a wide range of frequencies and ampli tudes. The inherent mobility of biomolecular edifices may be crucial to the adaptation of their structures to particular functions. Progress in methods for investigating macromolecular structures and dynamics make this hypothesis not only attractive but more and more testable.
Author : Greta Pifat-Mrzljak
Publisher : Springer Science & Business Media
ISBN 13 : 9780306486616
Total Pages : 308 pages
Book Rating : 4.4/5 (866 download)
Download or read book Supramolecular Structure and Function 8 written by Greta Pifat-Mrzljak and published by Springer Science & Business Media. This book was released on 2004-08-10 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers some powerful biophysical methods, such as analytical centrifugation, mass spectrometry, fluorescence spectroscopy, electron spin resonance and nuclear magnetic resonance, for the study of complex biological structures, and discusses useful physical concepts as applied to biological and biochemical systems. Case-orientated studies concentrating on particular methodologies are presented and examples are given, addressing some of the most important aspects of structure-function relationship in biological assemblies. Biophysics nowadays collaborates closely with molecular biology and bioinformatics and this is also demonstrated in this book. The book will be of interest both to experienced researchers wishing to widen their insight into molecular structure and function, and to younger scientists at the doctoral and postdoctoral level interested in the molecular nature of fundamental biological entities and phenomena.
Author : Miriam Balaban
Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structural Aspects of Recognition and Assembly in Biological Macromolecules: Nucleic acids and nucleic acid complexes ; Viruses written by Miriam Balaban and published by . This book was released on 1981 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Subrata Pal
Publisher : Academic Press
ISBN 13 : 0128148551
Total Pages : 518 pages
Book Rating : 4.1/5 (281 download)
Download or read book Fundamentals of Molecular Structural Biology written by Subrata Pal and published by Academic Press. This book was released on 2019-09-02 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease
Author : John J. Kasianowicz
Publisher : Springer Science & Business Media
ISBN 13 : 9781402006975
Total Pages : 46 pages
Book Rating : 4.0/5 (69 download)
Download or read book Structure and Dynamics of Confined Polymers written by John J. Kasianowicz and published by Springer Science & Business Media. This book was released on 2002-07-31 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers are essential to biology because they can have enough stable degrees of freedom to store the molecular code of heredity and to express the sequences needed to manufacture new molecules. Through these they perform or control virtually every function in life. Although some biopolymers are created and spend their entire career in the relatively large free space inside cells or organelles, many biopolymers must migrate through a narrow passageway to get to their targeted destination. This suggests the questions: How does confining a polymer affect its behavior and function? What does that tell us about the interactions between the monomers that comprise the polymer and the molecules that confine it? Can we design and build devices that mimic the functions of these nanoscale systems? The NATO Advanced Research Workshop brought together for four days in Bikal, Hungary over forty experts in experimental and theoretical biophysics, molecular biology, biophysical chemistry, and biochemistry interested in these questions. Their papers collected in this book provide insight on biological processes involving confinement and form a basis for new biotechnological applications using polymers. In his paper Edmund DiMarzio asks: What is so special about polymers? Why are polymers so prevalent in living things? The chemist says the reason is that a protein made of N amino acids can have any of 20 different kinds at each position along the chain, resulting in 20 N different polymers, and that the complexity of life lies in this variety.
Author : Finn Wold
Publisher : Prentice Hall
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)
Download or read book Macromolecules: Structure and Function written by Finn Wold and published by Prentice Hall. This book was released on 1971 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we discuss the status of the structure- function analysis of biological macromolecules and macromolecular complexes. The ultimate goal of the analysis must be to explain all the functional properties of the molecules in question in terms of their completely defined three-dimensional structure, and the analysis thus contains three separate components: the determination of structure, the determination and quantitation of function, and final correlation of this information into the structure-function model. The first component, the structural analysis, is reviewed only briefly, and this book therefore leans heavily on Barker's and Van Holde's books in this series for proper background and documentation for this component. The second component, the analysis of functional properties, is given broader consideration (Chapters I, 2, 5, and 9), but the main emphasis has been the step-by-step development of the structure-function models. It is hoped that this approach will clearly illustrate the typical progression of scientific model building from the first clear definition of the problem and the statement of the hypothesis through ever-increasing refinements of experimental tests toward the final answer. It is also hoped that the statements of philosophy, principles, and scientific method that are the bases for this approach are of broad enough validity to survive even after its models have become obsolete. With this approach, it is essential to inform the reader in unequivocal terms that this book is not a summary of final conclusions and complete stories which can be submitted to memory. Each system discussed should be considered very critically, and the models should be evaluated in terms of the available evidence. The only "facts" are the experimental data; the interpretation of this data into models is only convincing to the extent that it makes logical sense to the individual examining it. Since both space and common sense prohibits a continuous reiteration of this statement throughout the book, be prepared to encounter some models and hypotheses which are based on sound experimental evidence as well as some which have no experimental basis at all. In neither case are they "facts," but in either case they represent ideas which can be subjected to further experimental tests. If the book helps to sharpen this critical evaluation of both ideas and the experimental test of the hypotheses, one of its major purposes has been fulfilled.
Author : Eric Westhof
Publisher : World Scientific
ISBN 13 : 9812385002
Total Pages : 417 pages
Book Rating : 4.8/5 (123 download)
Download or read book Folding and Self-assembly of Biological Macromolecules written by Eric Westhof and published by World Scientific. This book was released on 2004 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers - and audience interaction - are edited and illustrated versions of the transcribed oral presentations.
Author : Keith Moffat
Publisher : John Wiley & Sons
ISBN 13 : 1119696283
Total Pages : 292 pages
Book Rating : 4.1/5 (196 download)
Download or read book Dynamics and Kinetics in Structural Biology written by Keith Moffat and published by John Wiley & Sons. This book was released on 2024-01-03 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the latest experimental tools in structural biology with this pioneering work Structural biology seeks to understand the chemical mechanisms and functions of biological molecules, such as proteins, based on their atomic structures. Until recently, these structures have been studied only statically, using procedures which deliberately freeze atomic motion. However, freezing eliminates the rapid structural motions so essential to biological activity and function; the molecules are inactive. But with the recent development of X-ray free electron laser (XFEL) sources, efforts to conduct dynamic experiments have expanded using the principles of dynamics and kinetics to capture active biological molecules as they function. Dynamics and Kinetics in Structural Biology promotes the development of these experiments and their successful application. It grounds readers in the foundational principles of dynamics and kinetics; proceeds through extended discussions of experimental procedures, data analysis techniques; and explores experimental frontiers in structural dynamics. The book will aid researchers to gather and interpret cutting-edge data on the dynamic structure of biological molecules, under conditions where they retain their biological functions. Dynamics and Kinetics in Structural Biology offers readers: Authorship by founding figures in the field In-depth presentation of time-resolved X-ray crystallography, solution scattering, and more A pioneering contribution to a rapidly developing field of study Dynamics and Kinetics in Structural Biology is essential reading for graduate students, scientists, researchers and industry professionals engaged in structural studies of biological systems. Industry professionals considering dynamic studies in the development of new product lines will also benefit.
Author : Miriam Balaban
Publisher :
ISBN 13 :
Total Pages : 546 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structural Aspects of Recognition and Assembly in Biological Macromolecules written by Miriam Balaban and published by . This book was released on 1981 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt:
