Structural Dynamics Of Hiv

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Structural Dynamics of HIV

Author : Deanna Kerrigan
Publisher : Springer
ISBN 13 : 3319635220
Total Pages : 211 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Structural Dynamics of HIV by : Deanna Kerrigan

Download or read book Structural Dynamics of HIV written by Deanna Kerrigan and published by Springer. This book was released on 2017-09-30 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the structural dynamics of HIV among populations at heightened vulnerability to infection as the result of stigma, discrimination and marginalization. It first examines how the socio-structural context shapes HIV risk and how affected populations and national governments and programs have responded to these structural constraints. Chapters focus on structural determinants of HIV risk among transgender women in Guatemala, migrant workers in Mexico, Nigeria and Vietnam, and people who inject drugs in Tanzania. Next, the book examines resilience and community empowerment and mobilization among key populations such as female sex workers in the Dominican Republic and India, and young women and girls in Botswana, Malawi and Mozambique. A third set of chapters explores how national responses to HIV have addressed the role of structural factors in diverse political, geographic and epidemic settings including: Brazil, South Africa, Ukraine and the USA. Ultimately, effective and sustainable responses to HIV among marginalized groups must be grounded in an in-depth understanding of the factors that create vulnerability and risk and impede access to services. Throughout, this book brings together a rigorous social science research perspective with a strong rights-based approach to inform improvements in HIV programs and policies. It offers new insights into how to better address HIV and the health and human rights of historically excluded communities and groups.

Structural Interventions for HIV Prevention

Author : Richard A. Crosby
Publisher : Oxford University Press
ISBN 13 : 0190930802
Total Pages : 384 pages
Book Rating : 4.1/5 (99 download)

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Book Synopsis Structural Interventions for HIV Prevention by : Richard A. Crosby

Download or read book Structural Interventions for HIV Prevention written by Richard A. Crosby and published by Oxford University Press. This book was released on 2018-10-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPREHENSIVE NEW REFERENCE WORK ON STRUCTURAL APPROACHES TO PREVENTING HIV Structural interventions -- changes to environment aimed at influencing health behaviors -- are the most universal and cost-effective tool in preventing new incidences of HIV. They are not easy to get right, however. Structural Interventions for HIV Prevention offers an authoritative reference for both understanding these programs and instituting them to greatest effect. Whether through changes to policy, environment, social/community norms, or a combination of each, this volume offers actionable and attainable blueprints to creating and evaluating programs in any setting or country. It is an essential resource for researchers and practitioners in the continuing fights against HIV.

HIV in US Communities of Color

Author : Bisola O. Ojikutu
Publisher : Springer Nature
ISBN 13 : 303048744X
Total Pages : 256 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis HIV in US Communities of Color by : Bisola O. Ojikutu

Download or read book HIV in US Communities of Color written by Bisola O. Ojikutu and published by Springer Nature. This book was released on 2020-08-21 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book builds upon its previous edition by comprehensively updating important epidemiologic and clinical content of the HIV continuum amongst Black and Latino individuals of the United States, including the epidemiology, prevention, diagnosis, and treatment of HIV within these diverse communities. Illuminating current diagnostic and prevention considerations, as well as its evidence base, the text highlights important concepts and integrates critical aspects of the structural and social environment, such as mass incarceration and neighborhood-level disadvantage, that compromise our ability to decrease HIV risk and improve outcomes. Discussion regarding significant predictors of health inequity, including discrimination, medical mistrust, and stigma, specifically homophobia and transphobia, are included. The book also reviews the impact of significant advances in HIV prevention, such as pre-exposure prophylaxis (PrEP), within Black and Latino communities. Written by experts in their field, this second edition of HIV in US Communities of Color is a comprehensive and dynamic resource for all health care providers who support the care and treatment of Black and Latino individuals at risk for or living with HIV.

Computational Structural Biology

Author : Torsten Schwede
Publisher : World Scientific
ISBN 13 : 9812778780
Total Pages : 790 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Computational Structural Biology by : Torsten Schwede

Download or read book Computational Structural Biology written by Torsten Schwede and published by World Scientific. This book was released on 2008 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Evidence-Based Health Economics

Author : Miranda Mugford
Publisher :
ISBN 13 : 9780470715888
Total Pages : 176 pages
Book Rating : 4.7/5 (158 download)

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Book Synopsis Evidence-Based Health Economics by : Miranda Mugford

Download or read book Evidence-Based Health Economics written by Miranda Mugford and published by . This book was released on 2014-05-28 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text recognises the need for evidence-based principles in economic evaluation, and that they should be based themselves on health economics. It discusses systematic review in economic analysis and suggests how to perform analyses in an evidence-based way.

Mass Spectrometry in Structural Biology and Biophysics

Author : Igor A. Kaltashov
Publisher : John Wiley & Sons
ISBN 13 : 1118232119
Total Pages : 312 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Mass Spectrometry in Structural Biology and Biophysics by : Igor A. Kaltashov

Download or read book Mass Spectrometry in Structural Biology and Biophysics written by Igor A. Kaltashov and published by John Wiley & Sons. This book was released on 2012-03-02 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to mass spectrometry techniques in biology and biophysics The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art. Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics, structural biology, and biopharmaceuticals, the book is a practical guide to understanding the role of MS techniques in biophysical research. Designed to meet the needs of both academic and industrial researchers, it makes mass spectrometry accessible to professionals in a range of fields, including biopharmaceuticals. This new edition has been significantly expanded and updated to include the most recent experimental methodologies and techniques, MS applications in biophysics and structural biology, methods for studying higher order structure and dynamics of proteins, an examination of other biopolymers and synthetic polymers, such as nucleic acids and oligosaccharides, and much more. Featuring high-quality illustrations that illuminate the concepts described in the text, as well as extensive references that enable the reader to pursue further study, Mass Spectrometry in Structural Biology and Biophysics is an indispensable resource for researchers and graduate students working in biophysics, structural biology, protein chemistry, and related fields.

African Americans and HIV/AIDS

Author : Donna Hubbard McCree, PhD, MPH, RPh
Publisher : Springer Science & Business Media
ISBN 13 : 0387783210
Total Pages : 324 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis African Americans and HIV/AIDS by : Donna Hubbard McCree, PhD, MPH, RPh

Download or read book African Americans and HIV/AIDS written by Donna Hubbard McCree, PhD, MPH, RPh and published by Springer Science & Business Media. This book was released on 2010-09-14 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among U. S. racial and ethnic minority populations, African American communities are the most disproportionately impacted and affected by HIV/AIDS (CDC, 2009; CDC, 2008). The chapters in this volume seek to explore factors that contribute to this disparity as well as methods for intervening and positively impacting the e- demic in the U. S. The book is divided into two sections. The first section includes chapters that explore specific contextual and structural factors related to HIV/AIDS transmission and prevention in African Americans. The second section is composed of chapters that address the latest in intervention strategies, including best-evidence and promising-evidence based behavioral interventions, program evaluation, cost effectiveness analyses and HIV testing and counseling. As background for the book, the Introduction provides a summary of the context and importance of other infectious disease rates, (i. e. , sexually transmitted diseases [STDs] and tubercu- sis), to HIV/AIDS prevention and treatment in African Americans and a brief introductory discussion on the major contextual factors related to the acquisition and transmission of STDs/HIV. Contextual Chapters Johnson & Dean author the first chapter in this section, which discusses the history and epidemiology of HIV/AIDS among African Americans. Specifically, this ch- ter provides a definition for and description of the US surveillance systems used to track HIV/AIDS and presents data on HIV or AIDS cases diagnosed between 2002 and 2006 and reported to CDC as of June 30, 2007.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Structural Biology in Drug Discovery

Author : Jean-Paul Renaud
Publisher : John Wiley & Sons
ISBN 13 : 1118900405
Total Pages : 688 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Structural Biology in Drug Discovery by : Jean-Paul Renaud

Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-01-27 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Genomics and computational science for virus research

Author : Hironori Sato
Publisher : Frontiers E-books
ISBN 13 : 2889191265
Total Pages : 183 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Genomics and computational science for virus research by : Hironori Sato

Download or read book Genomics and computational science for virus research written by Hironori Sato and published by Frontiers E-books. This book was released on with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biologically striking and clinically important feature of viruses is their rapid evolutionary dynamics in nature. The continual interactions between viruses and host organisms promote quick changes in virus populations, eventually leading to co-evolution of viruses and hosts for their survival. The structural and functional information on the interactions between viruses and hosts should provide a molecular and biological basis to understand infection, replication, cell/host-tropism, immune escape, pathogenesis, and direction of evolution of viruses. The information is also essential to develop methods to control transmission and replication of pathogenic viruses. However, the integrated information on the structure, function, and evolution of viruses and hosts has remained poorly accumulated, partly due to the limitation of analytical methods. Recent progress in genome science and computational approach may open up a new avenue of research of the interactions between viruses and hosts by integrating information on the structures, functions, and evolution. In this Research Topic, we welcome papers concerning the computer-assisted structural and functional studies based on genomic information, with theoretical or in combination with experimental approaches, for understanding molecules, infection, replication, cell/host-tropism, immune escape, pathogenesis, and evolution of viruses in nature.

Living with HIV in Post-Crisis Times

Author : David A.B. Murray
Publisher : Rowman & Littlefield
ISBN 13 : 1666901490
Total Pages : 255 pages
Book Rating : 4.6/5 (669 download)

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Book Synopsis Living with HIV in Post-Crisis Times by : David A.B. Murray

Download or read book Living with HIV in Post-Crisis Times written by David A.B. Murray and published by Rowman & Littlefield. This book was released on 2021-08-18 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, effective prevention and treatment policies have resulted in global health organizations claiming that the end of the HIV/AIDS crisis is near and that HIV/AIDS is now a chronic but manageable disease. These proclamations have been accompanied by stagnant or decreasing public interest in and financial support for people living with HIV and the organizations that support them, minimizing significant global disparities in the management and control of the HIV pandemic. The contributors to this edited collection explore how diverse communities of people living with HIV (PLHIV) and organizations that support them are navigating physical, social, political, and economic challenges during these so-called “post-crisis” times.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 506 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Molecular Structures and Structural Dynamics of Prion Proteins and Prions

Author : Jiapu Zhang
Publisher : Springer
ISBN 13 : 9401773181
Total Pages : 355 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Molecular Structures and Structural Dynamics of Prion Proteins and Prions by : Jiapu Zhang

Download or read book Molecular Structures and Structural Dynamics of Prion Proteins and Prions written by Jiapu Zhang and published by Springer. This book was released on 2015-09-14 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by the body's own proteins, are invariably fatal and highly infectious neurodegenerative diseases effecting humans and almost all animals for a major public health concern. Prion contains no nucleic acids and it is a misshapen or conformation-changed protein that acts like an infectious agent; thus prion diseases are called “protein structural conformational” diseases. PrPC is predominant in α-helices but PrPSc are rich in β-sheets in the form as amyloid fibrils; so very amenable to be studied by MD techniques. Through MD, studies on the protein structures and the structural conversion are very important for revealing secrets of prion diseases and for structure-based drug design or discovery. Rabbits, dogs, horses and buffaloes are reported to be the few low susceptibility species to prion diseases; this book's MD studies on these species are clearly helpful to understand the mechanism underlying the resistance to prion diseases. PrP(1-120) usually has no clear molecular structures; this book also studies this unstructured region through MD and especially MM techniques from the global optimization point of view. This book is ideal for practitioners in computing of biophysics, biochemistry, biomedicine, bioinformatics, cheminformatics, materials science and engineering, applied mathematics and theoretical physics, information technology, operations research, biostatistics, etc. As an accessible introduction to these fields, this book is also ideal as a teaching material for students.

Epidemiology of the Acquired Immunodeficiency Syndrome (AIDS)

Author : Thomas A. Peterman
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epidemiology of the Acquired Immunodeficiency Syndrome (AIDS) by : Thomas A. Peterman

Download or read book Epidemiology of the Acquired Immunodeficiency Syndrome (AIDS) written by Thomas A. Peterman and published by . This book was released on 1986 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Highly Mutable Animal RNA Viruses: Adaptation and Evolution

Author : Akio Adachi
Publisher : Frontiers Media SA
ISBN 13 : 2889453480
Total Pages : 421 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Highly Mutable Animal RNA Viruses: Adaptation and Evolution by : Akio Adachi

Download or read book Highly Mutable Animal RNA Viruses: Adaptation and Evolution written by Akio Adachi and published by Frontiers Media SA. This book was released on 2017-11-30 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses are widely present in nature, and numerous viral species with a variety of unique characteristics have been identified so far. Even now, new emerging or re-emerging viruses are being found or re-found as novel viral classes or as quasi-species. Indeed, viruses are everywhere. Of note, viruses are pivotal as targets and tools of basic and applied sciences. On one hand, portions of the viruses are infectious for animals including humans, and cause various diseases in infected hosts by distinct mechanisms and at a different level of severity. While many of viruses are known to co-exist quietly with their hosts, pathogenic viruses certainly affect and threaten our society as well as individuals to provoke serious medical or economic attention. We should act against certain dreadful and highly infectious viruses as a global problem. Animal RNA viruses can readily mutate to adapt themselves in their hostile environments for their survival. Resultant viruses may sometimes show essentially altered phenotypes from the original parental strains. This fundamental and general property of animal RNA viruses represents major extensive issues of scientific, medical, and/or economic importance. In this Research Topic, we have focused on the high mutability of animal RNA viruses, and selected relevant articles on animal viruses of broad-ranges such as primate lentiviruses, influenza viruses, paramyxoviruses, flaviviruses, rabies virus, norovirus, picornaviruses, and picobirnavirus. Each article has taken up intriguing aspects of the subject viruses. We are sure that readers acquire important information on virus mutation, adaptation, diversification, and evolution, and hope that researchers in the field related to virology gain some solid hints from the reported articles for further virological and /or medical studies. Finally, we thank all the contributing researchers in this Research Topic, entitled “Highly Mutable Animal RNA Viruses: Adaptation and Evolution”, for their elegant and interesting works.

Aging in Sub-Saharan Africa

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309180090
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Aging in Sub-Saharan Africa by : National Research Council

Download or read book Aging in Sub-Saharan Africa written by National Research Council and published by National Academies Press. This book was released on 2006-11-10 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: In sub-Saharan Africa, older people make up a relatively small fraction of the total population and are supported primarily by family and other kinship networks. They have traditionally been viewed as repositories of information and wisdom, and are critical pillars of the community but as the HIV/AIDS pandemic destroys family systems, the elderly increasingly have to deal with the loss of their own support while absorbing the additional responsibilities of caring for their orphaned grandchildren. Aging in Sub-Saharan Africa explores ways to promote U.S. research interests and to augment the sub-Saharan governments' capacity to address the many challenges posed by population aging. Five major themes are explored in the book such as the need for a basic definition of "older person," the need for national governments to invest more in basic research and the coordination of data collection across countries, and the need for improved dialogue between local researchers and policy makers. This book makes three major recommendations: 1) the development of a research agenda 2) enhancing research opportunity and implementation and 3) the translation of research findings.

Enzymes and Their Biotechnological Applications

Author : Pabulo H. Rampelotto
Publisher : MDPI
ISBN 13 : 3038421480
Total Pages : 467 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Enzymes and Their Biotechnological Applications by : Pabulo H. Rampelotto

Download or read book Enzymes and Their Biotechnological Applications written by Pabulo H. Rampelotto and published by MDPI. This book was released on 2018-10-02 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Enzymes and Their Biotechnological Applications" that was published in Biomolecules